Open Access

Roles of ubiquitin‑specific protease 13 in normal physiology and tumors (Review)

  • Authors:
    • Yun Tao
    • Xiaohong Xu
    • Rong Shen
    • Xiaobing Miao
    • Song He
  • View Affiliations

  • Published online on: December 14, 2023     https://doi.org/10.3892/ol.2023.14191
  • Article Number: 58
  • Copyright: © Tao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Ubiquitin‑specific protease 13 (USP13) is one of the most important deubiquitinases involved in various diseases. As deubiquitinases are components of the deubiquitination process, a significant post‑translational modification, they are potential treatment targets for different diseases. With recent technological developments, the structure of USP13 and its pathological and physiological functions have been investigated. However, USP13 expression and function differ in various diseases, especially in tumors, and the associated mechanisms are complex and remain to be fully investigated. The present review summarized the recent discoveries and the current understanding of the USP13 function in tumors.
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February-2024
Volume 27 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Tao Y, Xu X, Shen R, Miao X and He S: Roles of ubiquitin‑specific protease 13 in normal physiology and tumors (Review). Oncol Lett 27: 58, 2024.
APA
Tao, Y., Xu, X., Shen, R., Miao, X., & He, S. (2024). Roles of ubiquitin‑specific protease 13 in normal physiology and tumors (Review). Oncology Letters, 27, 58. https://doi.org/10.3892/ol.2023.14191
MLA
Tao, Y., Xu, X., Shen, R., Miao, X., He, S."Roles of ubiquitin‑specific protease 13 in normal physiology and tumors (Review)". Oncology Letters 27.2 (2024): 58.
Chicago
Tao, Y., Xu, X., Shen, R., Miao, X., He, S."Roles of ubiquitin‑specific protease 13 in normal physiology and tumors (Review)". Oncology Letters 27, no. 2 (2024): 58. https://doi.org/10.3892/ol.2023.14191