Open Access

Chidamide in combination with azacitidine for an elderly patient with peripheral T cell lymphoma‑not otherwise specified: A case report

  • Authors:
    • Heng Liu
    • Feng Xue
    • Rui Zhou
    • Hongjuan Tian
    • Junfeng Mao
    • Tao Wu
  • View Affiliations

  • Published online on: May 28, 2024     https://doi.org/10.3892/ol.2024.14474
  • Article Number: 341
  • Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Peripheral T cell lymphoma (PTCL) is a type of aggressive non‑Hodgkin's lymphoma with poor prognosis. PTCL‑not otherwise specified (PTCL‑NOS) is one of its most common pathological types. PTCL is not sensitive to conventional chemotherapy regimens and treatment is particularly limited in elderly patients due to their poor tolerance to chemotherapy. The present report shares the treatment experience of one elderly PTCL‑NOS case, which achieved complete remission by reduced‑intensity chemotherapy with chidamide in combination with azacitidine following the onset of organ failure and chemotherapy insensitivity. The 9‑month follow‑up showed sustained remission and the long‑term efficacy of this regimen is also promising.
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August-2024
Volume 28 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Liu H, Xue F, Zhou R, Tian H, Mao J and Wu T: Chidamide in combination with azacitidine for an elderly patient with peripheral T cell lymphoma‑not otherwise specified: A case report. Oncol Lett 28: 341, 2024
APA
Liu, H., Xue, F., Zhou, R., Tian, H., Mao, J., & Wu, T. (2024). Chidamide in combination with azacitidine for an elderly patient with peripheral T cell lymphoma‑not otherwise specified: A case report. Oncology Letters, 28, 341. https://doi.org/10.3892/ol.2024.14474
MLA
Liu, H., Xue, F., Zhou, R., Tian, H., Mao, J., Wu, T."Chidamide in combination with azacitidine for an elderly patient with peripheral T cell lymphoma‑not otherwise specified: A case report". Oncology Letters 28.2 (2024): 341.
Chicago
Liu, H., Xue, F., Zhou, R., Tian, H., Mao, J., Wu, T."Chidamide in combination with azacitidine for an elderly patient with peripheral T cell lymphoma‑not otherwise specified: A case report". Oncology Letters 28, no. 2 (2024): 341. https://doi.org/10.3892/ol.2024.14474