Endobronchial lipoma with obstructive pneumonia: A case report

Wang,Yinjiao; Du,Peng

doi:10.3892/ol.2024.14699

Endobronchial lipoma with obstructive pneumonia: A case report

Authors:
- Yinjiao Wang
- Peng Du
View Affiliations

Affiliations: Department of Radiology, The Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221000, P.R. China
Published online on: September 26, 2024 https://doi.org/10.3892/ol.2024.14699
Article Number: 566
Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

Endobronchial lipoma (EL) is a rare benign lung tumor, and its incidence rate only accounts for a tiny proportion of all lung tumors. EL has non‑specific clinical symptoms and signs, and chest computed tomography is helpful in diagnosis. When fat density nodules are found in the bronchial lumen with no enhancement, EL should be considered. Once this disease is diagnosed, bronchoscopic intervention therapy is the first choice for treatment, and patients generally have a good prognosis. The present report describes the diagnosis and treatment processes of a patient with EL. The patient sought medical attention due to recurrent fever, cough and white sputum for >1 month. The chest CT revealed a hypodensity nodule at the bronchial opening of the basal segment of the lower lobe of the left lung, with the margins showing foci of punctate calcification. The patient underwent a bronchoscopy and the pathological diagnosis was EL. In the present study, a literature review analysis is also included to provide a reference for the diagnosis and treatment of this disease.

View Figures

View References

1	Kim KS and Yang HS: Unusual locations of lipoma: Differential diagnosis of head and neck mass. Aust Fam Physician. 43:867–870. 2014.PubMed/NCBI
2	Emekli E and Gündoğdu E: A case of incidentally detected bladder lipoma and a review of the literature. Curr Med Imaging. 18:86–90. 2022. View Article : Google Scholar : PubMed/NCBI
3	Anbazhakan L, Ullah A, Munagala R, Bechara R, Elhelf I, Patel N and Karim NA: Endobronchial lipoma. Autops Case Rep. 12:e20213772022. View Article : Google Scholar : PubMed/NCBI
4	Griffeth EM, Whitson B, Huard D and Brown BR: Endobronchial lipoma: Case report and literature review. Am J Med Sci. 361:111–117. 2021. View Article : Google Scholar : PubMed/NCBI
5	Chen H, Wang S, Zhou J and Liu S: Endobronchial lipoma presenting as recurrent pneumonia. QJM. 113:834–835. 2020. View Article : Google Scholar : PubMed/NCBI
6	Kawasaki Y, Yamamoto K, Suda T, Saito D and Matsumoto I: Benign endobronchial lipoma causing repeated pneumonia. Respirol Case Rep. 11:e012372023. View Article : Google Scholar : PubMed/NCBI
7	Jiang H, Xin T, Pu W, Wang Y, Yan Y, Nan Y, Pan L and Jin F: Clinical characteristics, diagnosis, treatment and prognosis of endobronchial lipoma. Shaanxi Med J. 51:1206–1209. 2022.
8	Jaurrieta Largo S, de Vega Sánchez B and Disdier Vicente C: Endobronchial lipoma excision by cryotherapy and flexible bronchoscopy. Arch Bronconeumol (Engl Ed). 55:4902019. View Article : Google Scholar : PubMed/NCBI
9	Mertoğlu A, Tellioğlu E and Yücel N: Multiple endobronchial hamartoma. Clin Respir J. 11:263–266. 2017. View Article : Google Scholar : PubMed/NCBI
10	Razzaghi A and Anastakis DJ: Lipofibromatous hamartoma: Review of early diagnosis and treatment. Can J Surg. 48:394–399. 2005.PubMed/NCBI
11	Liew CJ, Tham KY, Poh AC and Tee A: Endobronchial lipoma. Singapore Med J. 58:510–511. 2017. View Article : Google Scholar : PubMed/NCBI
12	Rama Rao PS and Wallis J: Endobronchial lipoma. Eur J Cardiothorac Surg. 19:5122001. View Article : Google Scholar : PubMed/NCBI
13	Wang Y, Teng Y, Li J, Lin T, Lu N and Yuan Y: Endobronchial lipoma with tracheobronchial aspergillosis: A case report. Medicine (Baltimore). 100:e243812021. View Article : Google Scholar : PubMed/NCBI
14	Pavlov PV, Kiryukhin AP, Puzakov KB, Rzayev RT and Derinov AA: Endobronchial lipoma: A rare cause of subsegmental bronchial obstruction. Respirol Case Rep. 8:e005052019. View Article : Google Scholar : PubMed/NCBI
15	Skubitz KM, Cheng EY, Clohisy DR, Thompson RC and Skubitz AP: Differential gene expression in liposarcoma, lipoma, and adipose tissue. Cancer Invest. 23:105–118. 2005. View Article : Google Scholar : PubMed/NCBI
16	Yee EJ, Stewart CL, Clay MR and McCarter MM: Lipoma and its doppelganger: The atypical lipomatous tumor/well-differentiated liposarcoma. Surg Clin North Am. 102:637–656. 2022. View Article : Google Scholar : PubMed/NCBI
17	Manor E, Sion-Vardy N, Joshua BZ and Bodner L: Oral lipoma: Analysis of 58 new cases and review of the literature. Ann Diagn Pathol. 15:257–261. 2011. View Article : Google Scholar : PubMed/NCBI
18	Schmidt J, Bremmer F, Brockmann K, Kaulfuß S and Wollnik B: Progressive frontal intraosseous lipoma: Detection of the mosaic AKT1 variant discloses Proteus syndrome. Clin Genet. 102:239–241. 2022. View Article : Google Scholar : PubMed/NCBI
19	Weiss SW: Lipomatous tumors. Monogr Pathol. 38:207–239. 1996.PubMed/NCBI
20	Sugiyama K, Washimi K, Sato S, Hiruma T, Sakai M, Okubo Y, Miyagi Y and Yokose T: Differential diagnosis of lipoma and atypical lipomatous tumor/well-differentiated liposarcoma by cytological analysis. Diagn Cytopathol. 50:112–122. 2022. View Article : Google Scholar : PubMed/NCBI
21	Ida CM, Wang X, Erickson-Johnson MR, Wenger DE, Blute ML, Nascimento AG and Oliveira AM: Primary retroperitoneal lipoma: A soft tissue pathology heresy?: Report of a case with classic histologic, cytogenetics, and molecular genetic features. Am J Surg Pathol. 32:951–954. 2008. View Article : Google Scholar : PubMed/NCBI
22	Rubin BP and Dal Cin P: The genetics of lipomatous tumors. Semin Diagn Pathol. 18:286–293. 2001.PubMed/NCBI
23	Harris K, Dhillon S, Huang M, Kumar A and Qiu J: Endobronchial lipoma: Bronchoscopy, imaging and pathology. Ther Adv Respir Dis. 8:162–164. 2014. View Article : Google Scholar : PubMed/NCBI
24	Xu Q, Wu F, Ouyang X and Huang H: High frequency electric coagulation snare and high frequency electric coagulation in treatment of endobronchial lipoma: A case report and literature review. Int J Respir. 36:1710–1713. 2016.
25	Akella P, Jindal V, Bhandari BS and Siddiqui AD: Meta-analysis of a master mimicker: Endobronchial lipoma. Chin Clin Oncol. 9:112020. View Article : Google Scholar : PubMed/NCBI
26	Leichtle SW, McCabe V and Gupta A: Obstructing endobronchial lipoma. Ann Thorac Surg. 97:7142014. View Article : Google Scholar : PubMed/NCBI
27	Chen J, Xin T, Pan L, Li Y, Qian W, Wei J, Yan Y, Wang Y, Jin F and Jiang H: Endobronchial lipoma: A rare cause of bronchial stenosis or obstruction. Can Respir J. 2023:27994362023. View Article : Google Scholar : PubMed/NCBI
28	Muraoka M, Oka T, Akamine S, Nagayasu T, Iseki M, Suyama N and Ayabe H: Endobronchial lipoma: Review of 64 cases reported in Japan. Chest. 123:293–296. 2003. View Article : Google Scholar : PubMed/NCBI
29	Yang Y, Liu J, Chen S, Yang G, Mao G, Han X and Wang J: An unexpected encounter and outcome between endobronchial lipoma and carcinoma: A case report and literature review. Ther Adv Respir Dis. 17:175346662312085752023. View Article : Google Scholar : PubMed/NCBI
30	Dy RV, Patel S, Harris K and Mador MJ: Endobronchial lipoma causing progressive dyspnea. Respir Med Case Rep. 22:95–97. 2017.PubMed/NCBI
31	Sivapalan P, Gottlieb M, Christensen M and Clementsen PF: An obstructing endobronchial lipoma simulating COPD. Eur Clin Respir J. 1:10.3402/ecrj.v1.25664. 2014. View Article : Google Scholar : PubMed/NCBI
32	Moran CA, Suster S and Koss MN: Endobronchial lipomas: A clinicopathologic study of four cases. Mod Pathol. 7:212–214. 1994.PubMed/NCBI
33	Pollefliet C, Peters K, Janssens A, Luijks A, Van Bouwel E, Van Marck E and Germonpre P: Endobronchial lipomas: Rare benign lung tumors, two case reports. J Thorac Oncol. 4:658–660. 2009. View Article : Google Scholar : PubMed/NCBI
34	Huisman C, van Kralingen KW, Postmus PE and Sutedja TG: Endobronchial lipoma: A series of three cases and the role of electrocautery. Respiration. 67:689–692. 2000. View Article : Google Scholar : PubMed/NCBI
35	On R, Kushima H, Ishii H and Watanabe K: Endobronchial lipoma: The diagnostic benefit of computed tomography findings. Intern Med. 57:285–286. 2018. View Article : Google Scholar : PubMed/NCBI
36	Guelbenzu Zazpe JJ, Ramírez Gil E and Vilá Mayo E: Talking about endobronchial lipoma. Arch Bronconeumol. 51:251–252. 2015.(In English, Spanish). View Article : Google Scholar : PubMed/NCBI
37	Nussbaumer-Ochsner Y, Rassouli F, Uhlmann F and Thurnheer R: Endobronchial lipoma mimicking bronchial carcinoid tumour. Thorax. 70:8092015. View Article : Google Scholar : PubMed/NCBI
38	Einarsdottir H, Söderlund V, Larson O, Jenner G and Bauer HC: MR imaging of lipoma and liposarcoma. Acta Radiol. 40:64–68. 1999. View Article : Google Scholar : PubMed/NCBI
39	Elsayed H, Traify R, McKeon D and Poullis M: An endobronchial lipoma: Diagnosis remains a challenge. J Bronchology Interv Pulmonol. 17:95–96. 2010. View Article : Google Scholar : PubMed/NCBI
40	Basoglu A, Celik B, Akdag AO and Sengul AT: Endobronchial lipoma: A rare cause of bronchial occlusion. Interact Cardiovasc Thorac Surg. 3:263–264. 2004. View Article : Google Scholar : PubMed/NCBI
41	Martinez Trevino EF, Sohail M, Mijares-Rojas IA, Qaddorah S and Levenson A: Endobronchial obstruction: A case of well-differentiated liposarcoma. Cureus. 16:e577312024.PubMed/NCBI
42	Chetta A and Calzetta L: Bronchial asthma: An update. Minerva Med. 113:1–3. 2022. View Article : Google Scholar : PubMed/NCBI
43	Nakahama H, Hanada S, Takada K, Ishikawa N, Hirata N, Moriguchi S, Murase K, Miyamoto A, Fujii T, Ubukata K, et al: Obstructive pneumonia caused by Gordonia bronchialis with a bronchial foreign body. Int J Infect Dis. 124:157–158. 2022. View Article : Google Scholar : PubMed/NCBI
44	Zhang H, Yang J, Zhao W, Zhou J, He S, Shang Y and Cheng Q: Clinical features and risk factors of plastic bronchitis caused by refractory Mycoplasma pneumoniae pneumonia in children: A practical nomogram prediction model. Eur J Pediatr. 182:1239–1249. 2023. View Article : Google Scholar : PubMed/NCBI
45	Insler JE, Seder CW, Furlan K, Mir F, Reddy VB and Gattuso P: Benign endobronchial tumors: A clinicopathologic review. Front Surg. 8:6446562021. View Article : Google Scholar : PubMed/NCBI
46	Cao D, Sun Y and Yang S: Endobronchial lipoma: An unusual cause of bronchial obstruction. Case Rep Med. 2011:9398082011. View Article : Google Scholar : PubMed/NCBI
47	Triviño A, Mora-Cabezas M, Vallejo-Benitez A, García-Escudero A and González-Cámpora R: Endobronchial lipoma: A rare cause of bronchial occlusion. Arch Bronconeumol. 49:494–496. 2013.(In English, Spanish). View Article : Google Scholar : PubMed/NCBI
48	Rooijakkers M, Wynants J and Aumann J: Endobronchial lipoma, an extremely rare benign tumour of the lung, mimicking asthma bronchiale. Acta Clin Belg. 69:74–75. 2014. View Article : Google Scholar : PubMed/NCBI
49	Irani F, Kumar B, Reddy P, Narwal-Chadha R, Kasmani R and Tita J: An endobronchial lipoma mimicking asthma and malignancy. Prim Care Respir J. 19:281–283. 2010. View Article : Google Scholar : PubMed/NCBI