Open Access

Hyperbaric oxygen therapy enhances restoration of physical functional in patients with recurrent glioma: A case report

  • Authors:
    • Tengteng Cai
    • Tao Jin
    • Yun Guan
    • Wei Zou
    • Xin Wang
    • Yulian Zhu
  • View Affiliations

  • Published online on: October 2, 2024     https://doi.org/10.3892/ol.2024.14716
  • Article Number: 583
  • Copyright: © Cai et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Patients with recurrent glioblastoma often opt for hypofractionated stereotactic radiosurgery, which can cause various adverse reactions. The pharmacological interventions used to manage these adverse reactions are usually unsatisfactory. The present study reports the case of a patient with recurrent glioblastoma who underwent hyperbaric oxygen therapy followed by immediate hypofractionated stereotactic radiosurgery. Grip strength, isokinetic muscle testing and gait analysis were evaluated during the treatment period, spanning an interval of 7 days in March 2023. Assessments before and after treatment revealed improvements in all three parameters compared with pre‑treatment levels. In summary, combining hyperbaric oxygen therapy with hypofractionated stereotactic radiosurgery may enhance muscle strength in patients with recurrent glioblastoma. This treatment approach can lead to significant improvements in gait parameters, promoting better motor coordination. Furthermore, the combined therapy could offer a promising alternative for managing muscle weakness and mobility issues after glioblastoma recurrence.
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December-2024
Volume 28 Issue 6

Print ISSN: 1792-1074
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Spandidos Publications style
Cai T, Jin T, Guan Y, Zou W, Wang X and Zhu Y: Hyperbaric oxygen therapy enhances restoration of physical functional in patients with recurrent glioma: A case report. Oncol Lett 28: 583, 2024.
APA
Cai, T., Jin, T., Guan, Y., Zou, W., Wang, X., & Zhu, Y. (2024). Hyperbaric oxygen therapy enhances restoration of physical functional in patients with recurrent glioma: A case report. Oncology Letters, 28, 583. https://doi.org/10.3892/ol.2024.14716
MLA
Cai, T., Jin, T., Guan, Y., Zou, W., Wang, X., Zhu, Y."Hyperbaric oxygen therapy enhances restoration of physical functional in patients with recurrent glioma: A case report". Oncology Letters 28.6 (2024): 583.
Chicago
Cai, T., Jin, T., Guan, Y., Zou, W., Wang, X., Zhu, Y."Hyperbaric oxygen therapy enhances restoration of physical functional in patients with recurrent glioma: A case report". Oncology Letters 28, no. 6 (2024): 583. https://doi.org/10.3892/ol.2024.14716