Metastatic papillary thyroid carcinoma in the soft tissue of the breast in a male patient: A case report

Maráčková,Veronika; Vomáčková,Katherine; Skanderová,Daniela; Mathew,Eva; Urbánková,Markéta; Veverková,Lucia

doi:10.3892/ol.2024.14841

Metastatic papillary thyroid carcinoma in the soft tissue of the breast in a male patient: A case report

Authors:
- Veronika Maráčková
- Katherine Vomáčková
- Daniela Skanderová
- Eva Mathew
- Markéta Urbánková
- Lucia Veverková
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Affiliations: Department of Radiology, University Hospital Olomouc, Olomouc 77900, Czech Republic, Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc 77515, Czech Republic, Department of Clinical and Molecular Pathology, University Hospital Olomouc, Olomouc 77900, Czech Republic
Published online on: December 10, 2024 https://doi.org/10.3892/ol.2024.14841
Article Number: 95
Copyright: © Maráčková et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Papillary thyroid carcinoma (PTC) represents ~80% of all thyroid cancers, most frequently presenting in women in the third and fourth decade of life. The first clinical manifestation of PTC commonly includes a palpable mass in the thyroid area or cervical lymphadenopathy in cases of metastatic disease. Hematogenous distant metastases are a sign of an advanced stage of the tumour. The present study reported an extremely rare occurrence of solitary metastasis of a PTC in the left breast of a 63‑year‑old male patient, mimicking primary male breast cancer (MBC). The presence of a male breast lesion that did not follow the typical imaging criteria for MBC aroused suspicion of a different primary origin. The combination of imaging methods, laboratory findings and fine‑needle aspiration techniques enabling cytological and histopathological examination, with the use of a wide panel of immunohistochemical markers, is crucial to establishing a definitive and correct diagnosis.

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