Open Access

[Retracted] 5‑Fluorouracil‑induced apoptosis in colorectal cancer cells is caspase‑9‑dependent and mediated by activation of protein kinase C‑δ

  • Authors:
    • Nizar M. Mhaidat
    • Mohammed Bouklihacene
    • Rick F. Thorne
  • View Affiliations

  • Published online on: April 14, 2025     https://doi.org/10.3892/ol.2025.15042
  • Article Number: 296
  • Copyright : © Mhaidat et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

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Article

Following the publication of the above paper, concerns were raised about the presentation of data in Figs. 6 and 9. In Fig. 6 (and Fig. 9, which shared the same control β‑actin protein bands), it was drawn to the Editor’s attention that the leftmost pair of the β‑actin bands shown for the HCT116 experimental gels were strikingly similar to the rightmost β‑actin bands featured for the SW480 gels; furthermore, in Fig. 9, the phosphorylated (P)‑PKCε and PKCε panels for both the HCT116 and SW480 experiments also looked remarkably similar. Upon investigating this matter independently in the Editorial Office, the Editor of Oncology Letters has decided that this paper should be retracted from the Journal on the grounds of a lack of confidence in the presented data, with probable errors having been made in compiling the data in these figures. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. [Oncology Letters 8: 699‑704, 2014; DOI: 10.3892/ol.2014.2211]

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Spandidos Publications style
Mhaidat NM, Bouklihacene M and Thorne RF: [Retracted] 5‑Fluorouracil‑induced apoptosis in colorectal cancer cells is caspase‑9‑dependent and mediated by activation of protein kinase C‑δ. Oncol Lett 29: 296, 2025.
APA
Mhaidat, N.M., Bouklihacene, M., & Thorne, R.F. (2025). [Retracted] 5‑Fluorouracil‑induced apoptosis in colorectal cancer cells is caspase‑9‑dependent and mediated by activation of protein kinase C‑δ. Oncology Letters, 29, 296. https://doi.org/10.3892/ol.2025.15042
MLA
Mhaidat, N. M., Bouklihacene, M., Thorne, R. F."[Retracted] 5‑Fluorouracil‑induced apoptosis in colorectal cancer cells is caspase‑9‑dependent and mediated by activation of protein kinase C‑δ". Oncology Letters 29.6 (2025): 296.
Chicago
Mhaidat, N. M., Bouklihacene, M., Thorne, R. F."[Retracted] 5‑Fluorouracil‑induced apoptosis in colorectal cancer cells is caspase‑9‑dependent and mediated by activation of protein kinase C‑δ". Oncology Letters 29, no. 6 (2025): 296. https://doi.org/10.3892/ol.2025.15042