α-fetoprotein-producing endometrial adenocarcinoma without an obvious hepatoid component

  • Authors:
    • Junichi Kodama
    • Noriko Seki
    • Hiroyuki Yanai
    • Tomoyuki Kusumoto
    • Keiichiro Nakamura
    • Atsuchi Hongo
    • Yugi Hiramatsu
  • View Affiliations

  • Published online on: March 1, 2010     https://doi.org/10.3892/ol_00000043
  • Pages: 243-245
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Endometrial carcinomas producing α-fetoprotein (AFP) are extremely rare. We report a case of AFP-producing, Grade 2 endometrioid adenocarcinoma without an obvious hepatoid component. A 59-year-old multiparous woman presented with abdominal swelling. The serum level of AFP was 1292.8 ng/ml. Magnetic resonance images of the pelvis showed a markedly enlarged uterus, with a tumor growing exophytically within the endometrial cavity. Total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed. The histopathological examination demonstrated a Stage IIA, Grade 2 endometrioid adenocarcinoma without an obvious hepatoid component. The endometrioid adenocarcinoma cells were partly positive for AFP immunoreactivity. The patient received adjuvant chemotherapy and was disease-free 60 months after the operation. This case confirms the existence of AFP-producing endometrioid adenocarcinomas without hepatoid features.
View Figures
View References

Related Articles

Journal Cover

March-April 2010
Volume 1 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Kodama J, Seki N, Yanai H, Kusumoto T, Nakamura K, Hongo A and Hiramatsu Y: α-fetoprotein-producing endometrial adenocarcinoma without an obvious hepatoid component . Oncol Lett 1: 243-245, 2010.
APA
Kodama, J., Seki, N., Yanai, H., Kusumoto, T., Nakamura, K., Hongo, A., & Hiramatsu, Y. (2010). α-fetoprotein-producing endometrial adenocarcinoma without an obvious hepatoid component . Oncology Letters, 1, 243-245. https://doi.org/10.3892/ol_00000043
MLA
Kodama, J., Seki, N., Yanai, H., Kusumoto, T., Nakamura, K., Hongo, A., Hiramatsu, Y."α-fetoprotein-producing endometrial adenocarcinoma without an obvious hepatoid component ". Oncology Letters 1.2 (2010): 243-245.
Chicago
Kodama, J., Seki, N., Yanai, H., Kusumoto, T., Nakamura, K., Hongo, A., Hiramatsu, Y."α-fetoprotein-producing endometrial adenocarcinoma without an obvious hepatoid component ". Oncology Letters 1, no. 2 (2010): 243-245. https://doi.org/10.3892/ol_00000043