INDUCTION OF BREAST NEOPLASIA AND LUNG GRANULOMAS IN MICE BY AN ANTIFUNGAL DRUG (GRISEOFULVIN)

  • Authors:
    • MM ELMOFTY
    • MH SHWAIREB
    • AE ESSAWY
    • AM RIZK
    • HM ABDELKERIM
  • View Affiliations

  • Published online on: November 1, 1994     https://doi.org/10.3892/or.1.6.1079
  • Pages: 1079-1081
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Abstract

Infiltrating duct carcinomas were induced in the mammary glands of 7 out of 60 experimental female mice force-fed with the antifungal drug griseofulvin, at a daily dose lever of 0.3 mg/30g body weight, for 12 months. The first mammary gland tumor appeared 8 months after the initiation of feeding. Other pathological changes such as bronchocentric granulomas appeared in some male and female treated animals (16.5%).

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November 1994
Volume 1 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
ELMOFTY M, SHWAIREB M, ESSAWY A, RIZK A and ABDELKERIM H: INDUCTION OF BREAST NEOPLASIA AND LUNG GRANULOMAS IN MICE BY AN ANTIFUNGAL DRUG (GRISEOFULVIN). Oncol Rep 1: 1079-1081, 1994.
APA
ELMOFTY, M., SHWAIREB, M., ESSAWY, A., RIZK, A., & ABDELKERIM, H. (1994). INDUCTION OF BREAST NEOPLASIA AND LUNG GRANULOMAS IN MICE BY AN ANTIFUNGAL DRUG (GRISEOFULVIN). Oncology Reports, 1, 1079-1081. https://doi.org/10.3892/or.1.6.1079
MLA
ELMOFTY, M., SHWAIREB, M., ESSAWY, A., RIZK, A., ABDELKERIM, H."INDUCTION OF BREAST NEOPLASIA AND LUNG GRANULOMAS IN MICE BY AN ANTIFUNGAL DRUG (GRISEOFULVIN)". Oncology Reports 1.6 (1994): 1079-1081.
Chicago
ELMOFTY, M., SHWAIREB, M., ESSAWY, A., RIZK, A., ABDELKERIM, H."INDUCTION OF BREAST NEOPLASIA AND LUNG GRANULOMAS IN MICE BY AN ANTIFUNGAL DRUG (GRISEOFULVIN)". Oncology Reports 1, no. 6 (1994): 1079-1081. https://doi.org/10.3892/or.1.6.1079