|
1
|
Momparler RL: Epigenetic therapy of cancer
with 5-aza-2′-deoxycytidine (decitabine). Semin Oncol. 32:443–451.
2005.
|
|
2
|
Gassmann P, Enns A and Haier J: Role of
tumor cell adhesion and migration in organ-specific metastasis
formation. Onkologie. 27:577–582. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Soler AP, Miller RD, Laughlin KV, Carp NZ,
Klurfeld DM and Mullin JM: Increased tight junctional permeability
is associated with the development of colon cancer. Carcinogenesis.
20:1425–1431. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Schneeberger EE and Lynch RD: The tight
junction: a multifunctional complex. Am J Physiol Cell Physiol.
286:1213–1228. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Ruffer C and Gerke V: The C-terminal
cytoplasmic tail of claudins 1 and 5 but not its PDZ-binding motif
is required for apical localization at epithelial and endothelial
tight junctions. Eur J Cell Biol. 83:135–144. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Morin PJ: Claudin proteins in human
cancer: promising new targets for diagnosis and therapy. Cancer
Res. 65:9603–9606. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Rangel LB, Agarwal R, D’Souza T, Pizer ES,
Alò PL, Lancaster WD, Gregoire L, Schwartz DR, Cho KR and Morin PJ:
Tight junction proteins claudin-3 and claudin-4 are frequently
overexpressed in ovarian cancer but not in ovarian cystadenomas.
Clin Cancer Res. 9:2567–2575. 2003.PubMed/NCBI
|
|
8
|
Mees ST, Mennigen R, Spieker T, Rijcken E,
Senninger N, Haier J and Bruewer M: Expression of tight and
adherens junction proteins in ulcerative colitis associated
colorectal carcinoma: upregulation of claudin-1, claudin-3,
claudin-4 and beta-catenin. Int J Colorectal Dis. 24:361–368. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Ouban A and Ahmed AA: Claudins in human
cancer: a review. Histol Histopathol. 25:83–90. 2010.
|
|
10
|
Jung H, Jun KH, Jung JH, Chin HM and Park
WB: The expression of claudin-1, claudin-2, claudin-3, and
claudin-4 in gastric cancer tissue. J Surg Res. 167:e185–191. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Agarwal R, D’Souza T and Morin PJ:
Claudin-3 and claudin-4 expression in ovarian epithelial cells
enhances invasion and is associated with increased matrix
metalloproteinase-2 activity. Cancer Res. 65:7378–7385. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Sun C, Yi T, Song X, Li S, Qi X, Chen X,
Lin H, He X, Li Z, Wei Y and Zhao X: Efficient inhibition of
ovarian cancer by short hairpin RNA targeting claudin-3. Oncol Rep.
26:193–200. 2011.PubMed/NCBI
|
|
13
|
Yoon CH, Kim MJ, Park MJ, Park IC, Hwang
SG, An S, Choi YH, Yoon G and Lee SJ: Claudin-1 acts through
c-Abl-protein kinase Cdelta (PKCδ) signaling and has a causal role
in the acquisition of invasive capacity in human liver cells. J
Biol Chem. 285:226–233. 2010.PubMed/NCBI
|
|
14
|
Duffy MI, Maguire TM, Hill A, McDermott E
and O’Higgins N: Metalloproteinases: role in breast carcinogenesis,
invasion and metastasis. Breast Cancer Res. 2:252–257. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Vihinen P, Ala-aho R and Kähäri VM: Matrix
metalloproteinases as therapeutic targets in cancer. Curr Cancer
Drug Targets. 5:203–220. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Schwartz GK: Invasion and metastases in
gastric cancer: in vitro and in vivo models with clinical
correlations. Semin Oncol. 23:316–324. 1996.PubMed/NCBI
|
|
17
|
Yasui W, Oue N, Aung PP, Matsumura S,
Shutoh M and Nakayama H: Molecular-pathological prognostic factors
of gastric cancer: a review. Gastric Cancer. 8:86–94. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Patra SK and Bettuzzi S: Epigenetic
DNA-(cytosine-5-carbon) modifications: 5-aza-2′-deoxycytidine and
DNA-demethylation. Biochemistry (Mosc). 74:613–619. 2009.PubMed/NCBI
|
|
19
|
Jubb AM, Bell SM and Quirke P: Methylation
and colorectal cancer. J Pathol. 195:111–134. 2001. View Article : Google Scholar
|
|
20
|
Claus R, Almstedt M and Lübbert M:
Epigenetic treatment of hematopoietic malignancies: in vivo targets
of demethylating agents. Semin Oncol. 32:511–520. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Feinberg AP and Vogelstein B:
Hypomethylation distinguishes genes of some human cancers from
their normal counterparts. Nature. 301:89–92. 1983. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Goelz SE, Vogelstein B, Hamilton SR and
Feinberg AP: Hypomethylation of DNA from benign and malignant human
colon neoplasms. Science. 228:187–190. 1985. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Gomyo Y, Sasaki J, Branch C, Roth JA and
Mukhopadhyay T: 5-aza-2′-deoxycytidine upregulates caspase-9
expression cooperating with p53-induced apoptosis in human lung
cancer cells. Oncogene. 23:6779–6787. 2004.
|
|
24
|
Schnekenburger M, Grandjenette C, Ghelfi
J, Karius T, Foliguet B, Dicato M and Diederich M: Sustained
exposure to the DNA demethylating agent, 2′-deoxy-5-azacytidine,
leads to apoptotic cell death in chronic myeloid leukemia by
promoting differentiation, senescence, and autophagy. Biochem
Pharmacol. 81:364–378. 2011.PubMed/NCBI
|
|
25
|
Zhu W, Fu A, Hu J, Wang T, Luo Y, Peng M,
Ma Y, Wei Y and Chen L: 5-Formylhonokiol exerts anti-angiogenesis
activity via inactivating the ERK signaling pathway. Exp Mol Med.
43:146–152. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Grant-Tschudy KS and Wira CR: Effect of
oestradiol on mouse uterine epithelial cell tumour necrosis
factor-alpha release is mediated through uterine stromal cells.
Immunology. 115:99–107. 2005. View Article : Google Scholar
|
|
27
|
Song HY, Ju SM, Goh AR, Kwon DJ, Choi SY
and Park J: Suppression of TNF-alpha-induced MMP-9 expression by a
cell-permeable superoxide dismutase in keratinocytes. BMB Rep.
44:462–467. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Shukla S, Maclennan GT, Hartman DJ, Fu P,
Resnick MI and Gupta S: Activation of PI3K-Akt signaling pathway
promotes prostate cancer cell invasion. Int J Cancer.
121:1424–1432. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Chen JS, Wang Q, Fu XH, Huang XH, Chen XL,
Cao LQ, Chen LZ, Tan HX, Li W, Bi J and Zhang LJ: Involvement of
PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in
hepatocellular carcinoma: association with MMP-9. Hepatol Res.
39:177–186. 2009. View Article : Google Scholar
|
|
30
|
Matrisian LM: The matrix-degrading
metalloproteinases. Bioessays. 14:455–463. 1992. View Article : Google Scholar
|
|
31
|
Mook OR, Frederiks WM and Van Noorden CJ:
The role of gelatinases in colorectal cancer progression and
metastasis. Biochim Biophys Acta. 1705:69–89. 2004.PubMed/NCBI
|
|
32
|
Uzui H, Harpf A, Liu M, Doherty TM, Shukla
A and Chai N: Increased expression of membrane type 3-matrix
metalloproteinase in human atherosclerotic plaque: role of
activated macrophages and inflammatory cytokines. Circulation.
106:3024–3030. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Lambert E, Dasse E, Haye B and Petitfrere
E: TIMPs as multifacial proteins. Crit Rev Oncol Hematol.
49:187–198. 2004. View Article : Google Scholar
|
|
34
|
Martin TA and Jiang WG: Loss of tight
junction barrier function and its role in cancer metastasis.
Biochim Biophys Acta. 1788:872–891. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Latorre IJ, Roh MH, Frese KK, Weiss RS,
Margolis B and Javier RT: Viral oncoprotein-induced mislocalization
of select PDZ proteins disrupts tight junctions and causes polarity
defects in epithelial cells. J Cell Sci. 118:4283–4293. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Gitter AH, Bendfeldt K, Schmitz H,
Schulzke JD, Bentzel CJ and Fromm M: Epithelial barrier defects in
HT-29/B6 colonic cell monolayers induced by tumor necrosis factor.
Ann N Y Acad Sci. 915:193–203. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Verghese GM, Gutknecht MF and Caughey GH:
Prostasin regulates epithelial monolayer function: cell-specific
Gpld1-mediated secretion and functional role for GPI anchor. Am J
Physiol Cell Physiol. 291:1258–1270. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Van Deun K, Pasmans F, Van Immerseel F,
Ducatelle R and Haesebrouck F: Butyrate protects Caco-2 cells from
Campylobacter jejuni invasion and translocation. Br J Nutr.
100:480–484. 2008.PubMed/NCBI
|
|
39
|
Kim SO, Choi BT, Choi IW, Cheong J, Kim
GY, Kwon TK, Kim ND and Choi YH: Anti-invasive activity of histone
deacetylase inhibitors via the induction of Egr-1 and the
modulation of tight junction-related proteins in human
hepatocarcinoma cells. BMB Rep. 42:655–660. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Kim SO, Kwon JI, Jeong YK, Kim GY, Kim ND
and Choi YH: Induction of Egr-1 is associated with anti-metastatic
and anti-invasive ability of β-lapachone in human hepatocarcinoma
cells. Biosci Biotechnol Biochem. 71:2169–2176. 2007.PubMed/NCBI
|
|
41
|
Shin DY, Kim GY, Kim JI, Yoon MK, Kwon TK,
Lee SJ, Choi YW, Kang HS, Yoo YH and Choi YH: Anti-invasive
activity of diallyl disulfide through tightening of tight junctions
and inhibition of matrix metalloproteinase activities in LNCaP
prostate cancer cells. Toxicol In Vitro. 24:1569–1576. 2010.
View Article : Google Scholar
|
|
42
|
Mullin JM, Agostino N, Rendon-Huerta E and
Thornton JJ: Keynote review: epithelial and endothelial barriers in
human disease. Drug Discov Today. 10:395–408. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Kominsky SL, Vali M, Korz D, Gabig TG,
Weitzman SA, Argani P and Sukumar S: Clostridium perfringens
enterotoxin elicits rapid and specific cytolysis of breast
carcinoma cells mediated through tight junction proteins claudin 3
and 4. Am J Pathol. 164:1627–1633. 2004. View Article : Google Scholar
|
|
44
|
Kominsky SL, Argani P, Korz D, Evron E,
Raman V, Garrett E, Rein A, Sauter G, Kallioniemi OP and Sukumar S:
Loss of the tight junction protein claudin-7 correlates with
histological grade in both ductal carcinoma in situ and invasive
ductal carcinoma of the breast. Oncogene. 22:2021–2033. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Tokés AM, Kulka J, Paku S, Szik A, Páska
C, Novák PK, Szilák L, Kiss A, Bögi K and Schaff Z: Claudin-1, -3
and -4 proteins and mRNA expression in benign and malignant breast
lesions: a research study. Breast Cancer Res. 7:296–305.
2005.PubMed/NCBI
|
|
46
|
Cunningham SC, Kamangar F, Kim MP, Hammoud
S, Haque R, Iacobuzio-Donahue CA, Maitra A, Ashfaq R, Hustinx S,
Heitmiller RE, et al: Claudin-4, mitogen activated protein kinase
kinase 4, and stratifin are markers of gastric adenocarcinoma
precursor lesions. Cancer Epidemiol Biomarkers Prev. 15:281–287.
2004. View Article : Google Scholar
|
|
47
|
Michl P, Barth C, Buchholz M, Lerch MM,
Rolke M, Holzmann KH, Menke A, Fensterer H, Giehl K, Löhr M, et al:
Claudin-4 expression decreases invasiveness and metastatic
potential of pancreatic cancer. Cancer Res. 63:6265–6271.
2003.PubMed/NCBI
|
|
48
|
Miyamori H, Takino T, Kobayashi Y, Tokai
H, Itoh Y, Seiki M and Sato H: Claudin promotes activation of
pro-matrix metalloproteinase-2 mediated by membrane-type matrix
metalloproteinases. J Biol Chem. 276:28204–28211. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Ip YC, Cheung ST, Lee YT, Ho JC and Fan
ST: Inhibition of hepatocellular carcinoma invasion by suppression
of claudin-10 in HLE cells. Mol Cancer Ther. 6:2858–2867. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Reddy KB, Nabha SM and Atanaskova N: Role
of MAP kinase in tumor progression and invasion. Cancer Metastasis
Rev. 22:395–403. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Samuels Y and Ericson K: Oncogenic PI3K
and its role in cancer. Curr Opin Oncol. 18:77–82. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Thiery JP, Acloque H, Huang RY and Nieto
MA: Epithelial-mesenchymal transitions in development and disease.
Cell. 139:871–890. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Yilmaz M and Christofori G: EMT, the
cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev.
28:15–33. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Chakraborti S, Mandal M, Das S, Mandal A
and Chakraborti T: Regulation of matrix metalloproteinases: an
overview. Mol Cell Biochem. 253:269–285. 2003. View Article : Google Scholar : PubMed/NCBI
|
