Open Access

Radical trachelectomy: The first step of fertility preservation in young women with cervical cancer (Review)

  • Authors:
    • Salvatore Gizzo
    • Emanuele Ancona
    • Carlo Saccardi
    • Tito Silvio Patrelli
    • Roberto Berretta
    • Omar Anis
    • Marco Noventa
    • Anna Bertocco
    • Simone Fagherazzi
    • Michela Longone
    • Lucia Vendemiati
    • Donato D'Antona
    • Giovanni Battista Nardelli
  • View Affiliations

  • Published online on: September 19, 2013     https://doi.org/10.3892/or.2013.2736
  • Pages: 2545-2554
  • Copyright: © Gizzo et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY_NC 3.0].

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Abstract

Radical trachelectomy (RT) can be performed vaginally or abdominally (laparotomic, laparoscopic or robotic). The aim of this systematic review was to compare all techniques in terms of surgical complications, disease recurrence and subsequent fertility/pregnancy outcomes. A total of 1293 RTs were analyzed (FIGO-stage: IA1-IIA). The most frequent surgical complications do not differ from the ones of radical hysterectomy. The recurrence risk is approximately 3% (range 0-16.8%). The majority of women conceive spontaneously: 284 pregnancies with 173 live births. The most frequent pregnancy complication was miscarriage and chorioamnionitis. RT appears to be a safe option for eligible women who intend to maintain their future pregnancy desire.
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December 2013
Volume 30 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Gizzo S, Ancona E, Saccardi C, Patrelli TS, Berretta R, Anis O, Noventa M, Bertocco A, Fagherazzi S, Longone M, Longone M, et al: Radical trachelectomy: The first step of fertility preservation in young women with cervical cancer (Review). Oncol Rep 30: 2545-2554, 2013.
APA
Gizzo, S., Ancona, E., Saccardi, C., Patrelli, T.S., Berretta, R., Anis, O. ... Nardelli, G.B. (2013). Radical trachelectomy: The first step of fertility preservation in young women with cervical cancer (Review). Oncology Reports, 30, 2545-2554. https://doi.org/10.3892/or.2013.2736
MLA
Gizzo, S., Ancona, E., Saccardi, C., Patrelli, T. S., Berretta, R., Anis, O., Noventa, M., Bertocco, A., Fagherazzi, S., Longone, M., Vendemiati, L., D'Antona, D., Nardelli, G. B."Radical trachelectomy: The first step of fertility preservation in young women with cervical cancer (Review)". Oncology Reports 30.6 (2013): 2545-2554.
Chicago
Gizzo, S., Ancona, E., Saccardi, C., Patrelli, T. S., Berretta, R., Anis, O., Noventa, M., Bertocco, A., Fagherazzi, S., Longone, M., Vendemiati, L., D'Antona, D., Nardelli, G. B."Radical trachelectomy: The first step of fertility preservation in young women with cervical cancer (Review)". Oncology Reports 30, no. 6 (2013): 2545-2554. https://doi.org/10.3892/or.2013.2736