|
1
|
Jemal A, Siegel R, Ward E, et al: Cancer
statistics, 2006. CA Cancer J Clin. 56:106–130. 2006. View Article : Google Scholar
|
|
2
|
Renehan AG, Tyson M, Egger M, Heller RF
and Zwahlen M: Body-mass index and incidence of cancer: a
systematic review and meta-analysis of prospective observational
studies. Lancet. 371:569–578. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Calle EE and Thun MJ: Obesity and cancer.
Oncogene. 23:6365–6378. 2004. View Article : Google Scholar
|
|
4
|
Amemori S, Ootani A, Aoki S, et al:
Adipocytes and preadipocytes promote the proliferation of colon
cancer cells in vitro. Am J Physiol Gastrointest Liver Physiol.
292:G923–G929. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Halaas JL, Gajiwala KS, Maffei M, et al:
Weight-reducing effects of the plasma protein encoded by the obese
gene. Science. 269:543–546. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Huang L and Li C: Leptin: a
multifunctional hormone. Cell Res. 10:81–92. 2000. View Article : Google Scholar
|
|
7
|
Somasundar P, McFadden DW, Hileman SM and
Vona-Davis L: Leptin is a growth factor in cancer. J Surg Res.
116:337–349. 2004. View Article : Google Scholar
|
|
8
|
Zhang F, Chen Y, Heiman M and Dimarchi R:
Leptin: structure, function and biology. Vitam Horm. 71:345–372.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Garofalo C and Surmacz E: Leptin and
cancer. J Cell Physiol. 207:12–22. 2006. View Article : Google Scholar
|
|
10
|
Pai R, Lin C, Tran T and Tarnawski A:
Leptin activates STAT and ERK2 pathways and induces gastric cancer
cell proliferation. Biochem Biophys Res Commun. 331:984–992. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Rose DP, Komninou D and Stephenson GD:
Obesity, adipocytokines, and insulin resistance in breast cancer.
Obes Rev. 5:153–165. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Choi JH, Park SH, Leung PC and Choi KC:
Expression of leptin receptors and potential effects of leptin on
the cell growth and activation of mitogen-activated protein kinases
in ovarian cancer cells. J Clin Endocrinol Metab. 90:207–210. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Somasundar P, Frankenberry KA, Skinner H,
et al: Prostate cancer cell proliferation is influenced by leptin.
J Surg Res. 118:71–82. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Sharma D, Saxena NK, Vertino PM and Anania
FA: Leptin promotes the proliferative response and invasiveness in
human endometrial cancer cells by activating multiple
signal-transduction pathways. Endocr Relat Cancer. 13:629–640.
2006. View Article : Google Scholar
|
|
15
|
Stattin P, Palmqvist R, Söderberg S, et
al: Plasma leptin and colorectal cancer risk: a prospective study
in Northern Sweden. Oncol Rep. 10:2015–2021. 2003.PubMed/NCBI
|
|
16
|
Stattin P, Lukanova A, Biessy C, et al:
Obesity and colon cancer: Does leptin provide a link? Int J Cancer.
109:149–152. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Fenton JI, Hursting SD, Perkins SN and
Hord NG: Leptin induces an Apc genotype-associated colon epithelial
cell chemokine production pattern associated with macrophage
chemotaxis and activation. Carcinogenesis. 28:455–464. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Fenton JI, Lavigne JA, Perkins SN, et al:
Microarray analysis reveals that leptin induces autocrine/paracrine
cascades to promote survival and proliferation of colon epithelial
cells in an Apc genotype-dependent fashion. Mol Carcinog.
47:9–21. 2008. View
Article : Google Scholar
|
|
19
|
Yu F, Yao H, Zhu P, et al: let-7
regulates self renewal and tumorigenicity of breast cancer cells.
Cell. 131:1109–1123. 2007. View Article : Google Scholar
|
|
20
|
Yamaguchi H, Wyckoff J and Condeelis J:
Cell migration in tumors. Curr Opin Cell Biol. 17:559–564. 2005.
View Article : Google Scholar
|
|
21
|
Paik SS, Jang SM, Jang KS, Lee KH, Choi D
and Jang SJ: Leptin expression correlates with favorable
clinicopathologic phenotype and better prognosis in colorectal
adenocarcinoma. Ann Surg Oncol. 16:297–303. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Koda M, Sulkowska M, Kanczuga-Koda L,
Surmacz E and Sulkowski S: Overexpression of the obesity hormone
leptin in human colorectal cancer. J Clin Pathol. 60:902–906. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Liu H, Wan D, Pan Z, et al: Expression and
biological significance of leptin, leptin receptor, VEGF, and CD34
in colorectal carcinoma. Cell Biochem Biophys. 60:241–244. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Bolukbas FF, Kilic H, Bolukbas C, et al:
Serum leptin concentration and advanced gastrointestinal cancers: a
case controlled study. BMC Cancer. 4:292004. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Sălăgeanu A, Tucureanu C, Lerescu L, et
al: Serum levels of adipokines resistin and leptin in patients with
colon cancer. J Med Life. 3:416–420. 2010.PubMed/NCBI
|
|
26
|
Scopelliti A, Cammareri P, Catalano V,
Saladino V, Todaro M and Stassi G: Therapeutic implications of
cancer initiating cells. Expert Opin Biol Ther. 9:1005–1016. 2009.
View Article : Google Scholar
|
|
27
|
Bartucci M, Svensson S, Ricci-Vitiani L,
et al: Obesity hormone leptin induces growth and interferes with
the cytotoxic effects of 5-fluorouracil in colorectal tumor stem
cells. Endocr Relat Cancer. 17:823–833. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Singh SK, Hawkins C, Clarke ID, et al:
Identification of human brain tumour initiating cells. Nature.
432:396–401. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Dey D, Saxena M, Paranjape AN, et al:
Phenotypic and functional characterization of human mammary
stem/progenitor cells in long term culture. PLoS One. 4:e53292009.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Todaro M, Alea MP, Di Stefano AB, et al:
Colon cancer stem cells dictate tumor growth and resist cell death
by production of interleukin-4. Cell Stem Cell. 1:389–402. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Fan X, Ouyang N, Teng H and Yao H:
Isolation and characterization of spheroid cells from the HT29
colon cancer cell line. Int J Colorectal Dis. 26:1279–1285. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Kanwar SS, Yu Y, Nautiyal J, Patel BB and
Majumdar AP: The Wnt/β-catenin pathway regulates growth and
maintenance of colonospheres. Mol Cancer. 9:2122010.
|
|
33
|
O’Brien CA, Pollett A, Gallinger S and
Dick JE: A human colon cancer cell capable of initiating tumour
growth in immunodeficient mice. Nature. 445:106–110.
2007.PubMed/NCBI
|
|
34
|
Uchiyama T, Takahashi H, Sugiyama M, et
al: Leptin receptor is involved in STAT3 activation in human
colorectal adenoma. Cancer Sci. 102:367–372. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Vécsey-Semjén B, Becker KF, Sinski A, et
al: Novel colon cancer cell lines leading to better understanding
of the diversity of respective primary cancers. Oncogene.
21:4646–4662. 2002.PubMed/NCBI
|
