1
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar : PubMed/NCBI
|
2
|
Tang ZY: Hepatocellular carcinoma - cause,
treatment and metastasis. World J Gastroenterol. 7:445–454.
2001.
|
3
|
Thomas MB and Abbruzzese JL: Opportunities
for targeted therapies in hepatocellular carcinoma. J Clin Oncol.
23:8093–8108. 2005. View Article : Google Scholar : PubMed/NCBI
|
4
|
Whittaker S, Marais R and Zhu AX: The role
of signaling pathways in the development and treatment of
hepatocellular carcinoma. Oncogene. 29:4989–5005. 2010. View Article : Google Scholar : PubMed/NCBI
|
5
|
Garrett-Sinha LA, Eberspaecher H, Seldin
MF and de Crombrugghe B: A gene for a novel zinc-finger protein
expressed in differentiated epithelial cells and transiently in
certain mesenchymal cells. J Biol Chem. 271:31384–31390. 1996.
View Article : Google Scholar : PubMed/NCBI
|
6
|
Chen X, Whitney EM, Gao SY and Yang VW:
Transcriptional profiling of Krüppel-like factor 4 reveals a
function in cell cycle regulation and epithelial differentiation. J
Mol Biol. 326:665–677. 2003. View Article : Google Scholar : PubMed/NCBI
|
7
|
Hsu HT, Sung MT, Lee CC, Chang YF and Chi
CW: The role of gut-enriched Krüppel-like factor (GKLF)/KLF4 in
gastrointestinal tract-related cancers. J Cancer Res Pract.
27:191–199. 2011.
|
8
|
Zhao W, Hisamuddin IM, Nandan MO, Babbin
BA, Lamb NE and Yang VW: Identification of Krüppel-like factor 4 as
a potential tumor suppressor gene in colorectal cancer. Oncogene.
23:395–402. 2004. View Article : Google Scholar : PubMed/NCBI
|
9
|
Wei D, Gong W, Kanai M, Schlunk C, Wang L,
Yao JC, Wu TT, Huang S and Xie K: Drastic down-regulation of
Krüppel-like factor 4 expression is critical in human gastric
cancer development and progression. Cancer Res. 65:2746–2754. 2005.
View Article : Google Scholar : PubMed/NCBI
|
10
|
Wang N, Liu ZH, Ding F, Wang XQ, Zhou CN
and Wu M: Down-regulation of gut-enriched Kruppel-like factor
expression in esophageal cancer. World J Gastroenterol. 8:966–970.
2002.PubMed/NCBI
|
11
|
Hu W, Hofstetter WL, Li H, Zhou Y, He Y,
Pataer A, Wang L, Xie K, Swisher SG and Fang B: Putative
tumor-suppressive function of Kruppel-like factor 4 in primary lung
carcinoma. Clin Cancer Res. 15:5688–5695. 2009. View Article : Google Scholar : PubMed/NCBI
|
12
|
Foster KW, Ren S, Louro ID, Lobo-Ruppert
SM, McKie-Bell P, Grizzle W, Hayes MR, Broker TR, Chow LT and
Ruppert JM: Oncogene expression cloning by retroviral transduction
of adenovirus E1A-immortalized rat kidney RK3E cells:
Transformation of a host with epithelial features by c-MYC and the
zinc finger protein GKLF. Cell Growth Differ. 10:423–434.
1999.PubMed/NCBI
|
13
|
Li Q, Gao Y, Jia Z, Mishra L, Guo K, Li Z,
Le X, Wei D, Huang S and Xie K: Dysregulated Krüppel-like factor 4
and vitamin D receptor signaling contribute to progression of
hepatocellular carcinoma. Gastroenterology. 143:799–810.e1-2. 2012.
View Article : Google Scholar
|
14
|
Yori JL, Johnson E, Zhou G, Jain MK and
Keri RA: Kruppel-like factor 4 inhibits epithelial-to-mesenchymal
transition through regulation of E-cadherin gene expression. J Biol
Chem. 285:16854–16863. 2010. View Article : Google Scholar : PubMed/NCBI
|
15
|
Lin ZS, Chu HC, Yen YC, Lewis BC and Chen
YW: Krüppel-like factor 4, a tumor suppressor in hepatocellular
carcinoma cells reverts epithelial-mesenchymal transition by
suppressing slug expression. PLoS One. 7:e435932012. View Article : Google Scholar
|
16
|
Li S, Zhou Q, He H, Zhao Y and Liu Z:
Peroxisome proliferator-activated receptor γ agonists induce cell
cycle arrest through transcriptional regulation of Kruppel-like
factor 4 (KLF4). J Biol Chem. 288:4076–4084. 2013. View Article : Google Scholar : PubMed/NCBI
|
17
|
Bauvois B: New facets of matrix
metalloproteinases MMP-2 and MMP-9 as cell surface transducers:
Outside-in signaling and relationship to tumor progression. Biochim
Biophys Acta. 1825:29–36. 2012.
|
18
|
Nart D, Yaman B, Yilmaz F, Zeytunlu M,
Karasu Z and Kiliç M: Expression of matrix metalloproteinase-9 in
predicting prognosis of hepatocellular carcinoma after liver
transplantation. Liver Transpl. 16:621–630. 2010.PubMed/NCBI
|
19
|
Cui J, Dong BW, Liang P, Yu XL and Yu DJ:
Effect of c-myc, Ki-67, MMP-2 and VEGF expression on prognosis of
hepatocellular carcinoma patients undergoing tumor resection. World
J Gastroenterol. 10:1533–1536. 2004.PubMed/NCBI
|
20
|
Sakamoto Y, Mafune K, Mori M, Shiraishi T,
Imamura H, Mori M, Takayama T and Makuuchi M: Overexpression of
MMP-9 correlates with growth of small hepatocellular carcinoma. Int
J Oncol. 17:237–243. 2000.PubMed/NCBI
|
21
|
Gao ZH, Tretiakova MS, Liu WH, Gong C,
Farris PD and Hart J: Association of E-cadherin, matrix
metalloproteinases, and tissue inhibitors of metalloproteinases
with the progression and metastasis of hepatocellular carcinoma.
Mod Pathol. 19:533–540. 2006. View Article : Google Scholar : PubMed/NCBI
|
22
|
Giannelli G, Bergamini C, Marinosci F,
Fransvea E, Quaranta M, Lupo L, Schiraldi O and Antonaci S:
Clinical role of MMP-2/TIMP-2 imbalance in hepatocellular
carcinoma. Int J Cancer. 97:425–431. 2002. View Article : Google Scholar : PubMed/NCBI
|
23
|
Yang MH, Chen CL, Chau GY, Chiou SH, Su
CW, Chou TY, Peng WL and Wu JC: Comprehensive analysis of the
independent effect of twist and snail in promoting metastasis of
hepatocellular carcinoma. Hepatology. 50:1464–1474. 2009.
View Article : Google Scholar : PubMed/NCBI
|
24
|
Wei D, Kanai M, Jia Z, Le X and Xie K:
Kruppel-like factor 4 induces p27Kip1 expression in and
suppresses the growth and metastasis of human pancreatic cancer
cells. Cancer Res. 68:4631–4639. 2008. View Article : Google Scholar : PubMed/NCBI
|
25
|
Dang DT, Chen X, Feng J, Torbenson M, Dang
LH and Yang VW: Overexpression of Krüppel-like factor 4 in the
human colon cancer cell line RKO leads to reduced tumorigenicity.
Oncogene. 22:3424–3430. 2003. View Article : Google Scholar : PubMed/NCBI
|
26
|
Li H, Wang J, Xiao W, Xia D, Lang B, Yu G,
Guo X, Guan W, Wang Z, Hu Z, et al: Epigenetic alterations of
Krüppel-like factor 4 and its tumor suppressor function in renal
cell carcinoma. Carcinogenesis. 34:2262–2270. 2013. View Article : Google Scholar : PubMed/NCBI
|
27
|
Wang Y, Rosen H, Madtes DK, Shao B, Martin
TR, Heinecke JW and Fu X: Myeloperoxidase inactivates TIMP-1 by
oxidizing its N-terminal cysteine residue: An oxidative mechanism
for regulating proteolysis during inflammation. J Biol Chem.
282:31826–31834. 2007. View Article : Google Scholar : PubMed/NCBI
|
28
|
Reed MJ, Koike T, Sadoun E, Sage EH and
Puolakkainen P: Inhibition of TIMP1 enhances angiogenesis in vivo
and cell migration in vitro. Microvasc Res. 65:9–17. 2003.
View Article : Google Scholar : PubMed/NCBI
|
29
|
Ahn SM, Jeong SJ, Kim YS, Sohn Y and Moon
A: Retroviral delivery of TIMP-2 inhibits H-ras-induced migration
and invasion in MCF10A human breast epithelial cells. Cancer Lett.
207:49–57. 2004. View Article : Google Scholar : PubMed/NCBI
|
30
|
Wang J, Place RF, Huang V, Wang X, Noonan
EJ, Magyar CE, Huang J and Li LC: Prognostic value and function of
KLF4 in prostate cancer: RNAa and vector-mediated overexpression
identify KLF4 as an inhibitor of tumor cell growth and migration.
Cancer Res. 70:10182–10191. 2010. View Article : Google Scholar : PubMed/NCBI
|
31
|
Yang J and Weinberg RA:
Epithelial-mesenchymal transition: At the crossroads of development
and tumor metastasis. Dev Cell. 14:818–829. 2008. View Article : Google Scholar : PubMed/NCBI
|
32
|
Onder TT, Gupta PB, Mani SA, Yang J,
Lander ES and Weinberg RA: Loss of E-cadherin promotes metastasis
via multiple downstream transcriptional pathways. Cancer Res.
68:3645–3654. 2008. View Article : Google Scholar : PubMed/NCBI
|
33
|
Cano A, Pérez-Moreno MA, Rodrigo I,
Locascio A, Blanco MJ, del Barrio MG, Portillo F and Nieto MA: The
transcription factor snail controls epithelial-mesenchymal
transitions by repressing E-cadherin expression. Nat Cell Biol.
2:76–83. 2000. View
Article : Google Scholar : PubMed/NCBI
|
34
|
Song LB, Li J, Liao WT, Feng Y, Yu CP, Hu
LJ, Kong QL, Xu LH, Zhang X, Liu WL, et al: The polycomb group
protein Bmi-1 represses the tumor suppressor PTEN and induces
epithelial-mesenchymal transition in human nasopharyngeal
epithelial cells. J Clin Invest. 119:3626–3636. 2009. View Article : Google Scholar : PubMed/NCBI
|
35
|
Bourboulia D, Han H, Jensen-Taubman S,
Gavil N, Isaac B, Wei B, Neckers L and Stetler-Stevenson WG: TIMP-2
modulates cancer cell transcriptional profile and enhances
E-cadherin/beta-catenin complex expression in A549 lung cancer
cells. Oncotarget. 4:166–176. 2013.PubMed/NCBI
|
36
|
Hu L, Lau SH, Tzang CH, Wen JM, Wang W,
Xie D, Huang M, Wang Y, Wu MC, Huang JF, et al: Association of
Vimentin overexpression and hepatocellular carcinoma metastasis.
Oncogene. 23:298–302. 2004.
|
37
|
Kim KR, Choi HN, Lee HJ, Baek HA, Park HS,
Jang KY, Chung MJ and Moon WS: A peroxisome proliferator-activated
receptor γ antagonist induces vimentin cleavage and inhibits
invasion in high-grade hepatocellular carcinoma. Oncol Rep.
18:825–832. 2007.PubMed/NCBI
|