1
|
Katoh Y and Katoh M: Comparative genomics
on SLIT1, SLIT2, and SLIT3 orthologs. Oncol Rep. 14:1351–1355.
2005.PubMed/NCBI
|
2
|
Brose K, Bland KS, Wang KH, Arnott D,
Henzel W, Goodman CS, Tessier-Lavigne M and Kidd T: Slit proteins
bind Robo receptors and have an evolutionarily conserved role in
repulsive axon guidance. Cell. 96:795–806. 1999. View Article : Google Scholar : PubMed/NCBI
|
3
|
Patel K, Nash JA, Itoh A, Liu Z,
Sundaresan V and Pini A: Slit proteins are not dominant
chemorepellents for olfactory tract and spinal motor axons.
Development. 128:5031–5037. 2001.PubMed/NCBI
|
4
|
Condac E, Strachan H, Gutierrez-Sanchez G,
Brainard B, Giese C, Heiss C, Johnson D, Azadi P, Bergmann C,
Orlando R, et al: The C-terminal fragment of axon guidance molecule
Slit3 binds heparin and neutralizes heparin’s anticoagulant
activity. Glycobiology. 22:1183–1192. 2012. View Article : Google Scholar : PubMed/NCBI
|
5
|
Wu JY, Feng L, Park HT, Havlioglu N, Wen
L, Tang H, Bacon KB, Jiang Zh, Zhang Xc and Rao Y: The neuronal
repellent Slit inhibits leukocyte chemotaxis induced by chemotactic
factors. Nature. 410:948–952. 2001. View
Article : Google Scholar : PubMed/NCBI
|
6
|
Shyamsundar R, Kim YH, Higgins JP,
Montgomery K, Jorden M, Sethuraman A, van de Rijn M, Botstein D,
Brown PO and Pollack JR: A DNA microarray survey of gene expression
in normal human tissues. Genome Biol. 6:R222005. View Article : Google Scholar : PubMed/NCBI
|
7
|
Dallol A, Da Silva NF, Viacava P, Minna
JD, Bieche I, Maher ER and Latif F: SLIT2, a human homologue of the
Drosophila Slit2 gene, has tumor suppressor activity and is
frequently inactivated in lung and breast cancers. Cancer Res.
62:5874–5880. 2002.PubMed/NCBI
|
8
|
Dickinson RE, Dallol A, Bieche I, Krex D,
Morton D, Maher ER and Latif F: Epigenetic inactivation of SLIT3
and SLIT1 genes in human cancers. Br J Cancer. 91:2071–2078. 2004.
View Article : Google Scholar : PubMed/NCBI
|
9
|
Dallol A, Krex D, Hesson L, Eng C, Maher
ER and Latif F: Frequent epigenetic inactivation of the SLIT2 gene
in gliomas. Oncogene. 22:4611–4616. 2003. View Article : Google Scholar : PubMed/NCBI
|
10
|
Dunwell TL, Dickinson RE, Stankovic T,
Dallol A, Weston V, Austen B, Catchpoole D, Maher ER and Latif F:
Frequent epigenetic inactivation of the SLIT2 gene in chronic and
acute lymphocytic leukemia. Epigenetics. 4:265–269. 2009.
View Article : Google Scholar : PubMed/NCBI
|
11
|
Chen WF, Gao WD, Li QL, Zhou PH, Xu MD and
Yao LQ: SLIT2 inhibits cell migration in colorectal cancer through
the AKT-GSK3β signaling pathway. Int J Colorectal Dis. 28:933–940.
2013. View Article : Google Scholar : PubMed/NCBI
|
12
|
Kim HK, Zhang H, Li H, Wu TT, Swisher S,
He D, Wu L, Xu J, Elmets CA, Athar M, et al: Slit2 inhibits growth
and metastasis of fibrosarcoma and squamous cell carcinoma.
Neoplasia. 10:1411–1420. 2008. View Article : Google Scholar : PubMed/NCBI
|
13
|
Göhrig A, Detjen KM, Hilfenhaus G, Körner
JL, Welzel M, Arsenic R, Schmuck R, Bahra M, Wu JY, Wiedenmann B,
et al: Axon guidance factor SLIT2 inhibits neural invasion and
metastasis in pancreatic cancer. Cancer Res. 74:1529–1540. 2014.
View Article : Google Scholar : PubMed/NCBI
|
14
|
Werbowetski-Ogilvie TE, Seyed Sadr M,
Jabado N, Angers-Loustau A, Agar NY, Wu J, Bjerkvig R, Antel JP,
Faury D, Rao Y, et al: Inhibition of medulloblastoma cell invasion
by Slit. Oncogene. 25:5103–5112. 2006.PubMed/NCBI
|
15
|
Dallol A, Morton D, Maher ER and Latif F:
SLIT2 axon guidance molecule is frequently inactivated in
colorectal cancer and suppresses growth of colorectal carcinoma
cells. Cancer Res. 63:1054–1058. 2003.PubMed/NCBI
|
16
|
Qiu H, Zhu J, Yu J, Pu H and Dong R: SLIT2
is epigenetically silenced in ovarian cancers and suppresses growth
when activated. Asian Pac J Cancer Prev. 12:791–795.
2011.PubMed/NCBI
|
17
|
Marlow R, Strickland P, Lee JS, Wu X,
Pebenito M, Binnewies M, Le EK, Moran A, Macias H, Cardiff RD, et
al: SLITs suppress tumor growth in vivo by silencing Sdf1/Cxcr4
within breast epithelium. Cancer Res. 68:7819–7827. 2008.
View Article : Google Scholar : PubMed/NCBI
|
18
|
Wang B, Xiao Y, Ding BB, Zhang N, Yuan X,
Gui L, Qian KX, Duan S, Chen Z, Rao Y, et al: Induction of tumor
angiogenesis by Slit-Robo signaling and inhibition of cancer growth
by blocking Robo activity. Cancer Cell. 4:19–29. 2003. View Article : Google Scholar : PubMed/NCBI
|
19
|
Wang LJ, Zhao Y, Han B, Ma YG, Zhang J,
Yang DM, Mao JW, Tang FT, Li WD, Yang Y, et al: Targeting
Slit-Roundabout signaling inhibits tumor angiogenesis in
chemical-induced squamous cell carcinogenesis. Cancer Sci.
99:510–517. 2008. View Article : Google Scholar : PubMed/NCBI
|
20
|
Qi C, Lan H, Ye J, Li W, Wei P, Yang Y,
Guo S, Lan T, Li J, Zhang Q, et al: Slit2 promotes tumor growth and
invasion in chemically induced skin carcinogenesis. Lab Invest.
94:766–776. 2014. View Article : Google Scholar : PubMed/NCBI
|
21
|
Zhou WJ, Geng ZH, Chi S, Zhang W, Niu XF,
Lan SJ, Ma L, Yang X, Wang LJ, Ding YQ, et al: Slit-Robo signaling
induces malignant transformation through Hakai-mediated E-cadherin
degradation during colorectal epithelial cell carcinogenesis. Cell
Res. 21:609–626. 2011. View Article : Google Scholar : PubMed/NCBI
|
22
|
Yang XM, Han HX, Sui F, Dai YM, Chen M and
Geng JG: Slit-Robo signaling mediates lymphangiogenesis and
promotes tumor lymphatic metastasis. Biochem Biophys Res Commun.
396:571–577. 2010. View Article : Google Scholar : PubMed/NCBI
|
23
|
Liu J, Zhang L, Wang D, Shen H, Jiang M,
Mei P, Hayden PS, Sedor JR and Hu H: Congenital diaphragmatic
hernia, kidney agenesis and cardiac defects associated with
Slit3-deficiency in mice. Mech Dev. 120:1059–1070. 2003. View Article : Google Scholar : PubMed/NCBI
|
24
|
Yuan W, Rao Y, Babiuk RP, Greer JJ, Wu JY
and Ornitz DM: A genetic model for a central (septum transversum)
congenital diaphragmatic hernia in mice lacking Slit3. Proc Natl
Acad Sci USA. 100:5217–5222. 2003. View Article : Google Scholar : PubMed/NCBI
|
25
|
Zhang B, Dietrich UM, Geng JG, Bicknell R,
Esko JD and Wang L: Repulsive axon guidance molecule Slit3 is a
novel angiogenic factor. Blood. 114:4300–4309. 2009. View Article : Google Scholar : PubMed/NCBI
|
26
|
Paul JD, Coulombe KL, Toth PT, Zhang Y,
Marsboom G, Bindokas VP, Smith DW, Murry CE and Rehman J:
SLIT3-ROBO4 activation promotes vascular network formation in human
engineered tissue and angiogenesis in vivo. J Mol Cell Cardiol.
64:124–131. 2013. View Article : Google Scholar : PubMed/NCBI
|
27
|
Narayan G, Goparaju C, Arias-Pulido H,
Kaufmann AM, Schneider A, Dürst M, Mansukhani M, Pothuri B and
Murty VV: Promoter hypermethylation-mediated inactivation of
multiple Slit-Robo pathway genes in cervical cancer progression.
Mol Cancer. 5:162006. View Article : Google Scholar : PubMed/NCBI
|
28
|
Nones K, Waddell N, Song S, Patch AM,
Miller D, Johns A, Wu J, Kassahn KS, Wood D, Bailey P, et al:
Genome-wide DNA methylation patterns in pancreatic ductal
adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2
and MET signaling. Int J Cancer. 135:1110–1118. 2014. View Article : Google Scholar : PubMed/NCBI
|
29
|
Dammann R, Strunnikova M, Schagdarsurengin
U, Rastetter M, Papritz M, Hattenhorst UE, Hofmann HS, Silber RE,
Burdach S and Hansen G: CpG island methylation and expression of
tumour-associated genes in lung carcinoma. Eur J Cancer.
41:1223–1236. 2005. View Article : Google Scholar : PubMed/NCBI
|
30
|
Denk AE, Braig S, Schubert T and
Bosserhoff AK: Slit3 inhibits activator protein 1-mediated
migration of malignant melanoma cells. Int J Mol Med. 28:721–726.
2011.PubMed/NCBI
|
31
|
Schubert T, Denk AE, Ruedel A, Kaufmann S,
Hustert E, Bastone P and Bosserhoff AK: Fragments of SLIT3 inhibit
cellular migration. Int J Mol Med. 30:1133–1137. 2012.PubMed/NCBI
|
32
|
Guan H, Wei G, Wu J, Fang D, Liao Z, Xiao
H, Li M and Li Y: Down-regulation of miR-218-2 and its host gene
SLIT3 cooperate to promote invasion and progression of thyroid
cancer. J Clin Endocrinol Metab. 98:E1334–E1344. 2013. View Article : Google Scholar : PubMed/NCBI
|
33
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2−ΔΔCT method. Methods. 25:402–408. 2001. View Article : Google Scholar
|
34
|
Bhattacharjee A, Richards WG, Staunton J,
Li C, Monti S, Vasa P, Ladd C, Beheshti J, Bueno R, Gillette M, et
al: Classification of human lung carcinomas by mRNA expression
profiling reveals distinct adenocarcinoma subclasses. Proc Natl
Acad Sci USA. 98:13790–13795. 2001. View Article : Google Scholar : PubMed/NCBI
|
35
|
Hou J, Aerts J, den Hamer B, van Ijcken W,
den Bakker M, Riegman P, van der Leest C, van der Spek P, Foekens
JA, Hoogsteden HC, et al: Gene expression-based classification of
non-small cell lung carcinomas and survival prediction. PLoS One.
5:e103122010. View Article : Google Scholar : PubMed/NCBI
|
36
|
Towner RA, Jensen RL, Vaillant B, Colman
H, Saunders D, Giles CB and Wren JD: Experimental validation of 5
in-silico predicted glioma biomarkers. Neuro Oncol. 15:1625–1634.
2013. View Article : Google Scholar : PubMed/NCBI
|
37
|
Lin ZY and Chuang WL: Genes responsible
for the characteristics of primary cultured invasive phenotype
hepatocellular carcinoma cells. Biomed Pharmacother. 66:454–458.
2012. View Article : Google Scholar : PubMed/NCBI
|
38
|
Chen G, Gharib TG, Huang CC, Taylor JM,
Misek DE, Kardia SL, Giordano TJ, Iannettoni MD, Orringer MB,
Hanash SM, et al: Discordant protein and mRNA expression in lung
adenocarcinomas. Mol Cell Proteomics. 1:304–313. 2002. View Article : Google Scholar : PubMed/NCBI
|
39
|
Hu H: Chemorepulsion of neuronal migration
by Slit2 in the developing mammalian forebrain. Neuron. 23:703–711.
1999. View Article : Google Scholar : PubMed/NCBI
|
40
|
Niclou SP, Jia L and Raper JA: Slit2 is a
repellent for retinal ganglion cell axons. J Neurosci.
20:4962–4974. 2000.PubMed/NCBI
|
41
|
Nguyen Ba-Charvet KT, Brose K, Ma L, Wang
KH, Marillat V, Sotelo C, Tessier-Lavigne M and Chédotal A:
Diversity and specificity of actions of Slit2 proteolytic fragments
in axon guidance. J Neurosci. 21:4281–4289. 2001.PubMed/NCBI
|
42
|
Bagri A, Marín O, Plump AS, Mak J,
Pleasure SJ, Rubenstein JL and Tessier-Lavigne M: Slit proteins
prevent midline crossing and determine the dorsoventral position of
major axonal pathways in the mammalian forebrain. Neuron.
33:233–248. 2002. View Article : Google Scholar : PubMed/NCBI
|
43
|
Prasad A, Fernandis AZ, Rao Y and Ganju
RK: Slit proteinmediated inhibition of CXCR4-induced chemotactic
and chemoinvasive signaling pathways in breast cancer cells. J Biol
Chem. 279:9115–9124. 2004. View Article : Google Scholar
|
44
|
Lim R, Barker G and Lappas M: SLIT3 is
increased in supracervical human foetal membranes and in labouring
myometrium and regulates pro-inflammatory mediators. Am J Reprod
Immunol. 71:297–311. 2014. View Article : Google Scholar
|
45
|
Autiero M, De Smet F, Claes F and
Carmeliet P: Role of neural guidance signals in blood vessel
navigation. Cardiovasc Res. 65:629–638. 2005. View Article : Google Scholar : PubMed/NCBI
|