Overall survival with and without laryngeal function preservation in 580 patients with hypopharyngeal squamous cell carcinoma

  • Authors:
    • Jieyu Zhou
    • Yongmei Li
    • Dongmin Wei
    • Ye Qian
    • Wenming Li
    • Dayu Liu
    • Guojun Li
    • Xinliang Pan
    • Dapeng Lei
  • View Affiliations

  • Published online on: September 28, 2015     https://doi.org/10.3892/or.2015.4313
  • Pages: 3196-3202
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The aims of the present study were to review the experience of different surgical reconstruction methods for hypopharyngeal squamous cell carcinoma (HSCC) and compared the survival of patients with and without laryngeal function (LF) preservation. The clinical characteristics of 580 patients were retrospectively obtained and analyzed. Survival curves were analyzed using the Kaplan‑Meier method for survival and Cox models for hazard ratios (HRs) with 95% confidence intervals (CIs). LF was preserved in 403 cases and not preserved in 177 cases. The 3‑ and 5‑year survival rates were 70.9 and 52.7%, respectively, in the LF preservation group and 48.4 and 30.5%, respectively, in the no LF preservation group. Compared with the patients without LF preservation, patients with LF preservation had a significantly reduced risk of overall death (HR=0.63, 95% CI: 0.50-0.80). LF preservation positively affects the prognosis of patients with HSCC.
View Figures
View References

Related Articles

Journal Cover

December-2015
Volume 34 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Zhou J, Li Y, Wei D, Qian Y, Li W, Liu D, Li G, Pan X and Lei D: Overall survival with and without laryngeal function preservation in 580 patients with hypopharyngeal squamous cell carcinoma. Oncol Rep 34: 3196-3202, 2015.
APA
Zhou, J., Li, Y., Wei, D., Qian, Y., Li, W., Liu, D. ... Lei, D. (2015). Overall survival with and without laryngeal function preservation in 580 patients with hypopharyngeal squamous cell carcinoma. Oncology Reports, 34, 3196-3202. https://doi.org/10.3892/or.2015.4313
MLA
Zhou, J., Li, Y., Wei, D., Qian, Y., Li, W., Liu, D., Li, G., Pan, X., Lei, D."Overall survival with and without laryngeal function preservation in 580 patients with hypopharyngeal squamous cell carcinoma". Oncology Reports 34.6 (2015): 3196-3202.
Chicago
Zhou, J., Li, Y., Wei, D., Qian, Y., Li, W., Liu, D., Li, G., Pan, X., Lei, D."Overall survival with and without laryngeal function preservation in 580 patients with hypopharyngeal squamous cell carcinoma". Oncology Reports 34, no. 6 (2015): 3196-3202. https://doi.org/10.3892/or.2015.4313