1
|
Ferlay J, Soerjomataram I, Dikshit R, Eser
S, Mathers C, Rebelo M, Parkin DM, Forman D and Bray F: Cancer
incidence and mortality worldwide: Sources, methods and major
patterns in GLOBOCAN 2012. Int J Cancer. 136:359–386. 2015.
View Article : Google Scholar
|
2
|
Bang YJ, Kim YW, Yang HK, Chung HC, Park
YK, Lee KH, Lee KW, Kim YH, Noh SI, Cho JY, et al CLASSIC trial
investigators: Adjuvant capecitabine and oxaliplatin for gastric
cancer after D2 gastrectomy (CLASSIC): A phase 3 open-label,
randomised controlled trial. Lancet. 379:315–321. 2012. View Article : Google Scholar : PubMed/NCBI
|
3
|
Sasako M, Sakuramoto S, Katai H, Kinoshita
T, Furukawa H, Yamaguchi T, Nashimoto A, Fujii M, Nakajima T and
Ohashi Y: Five-year outcomes of a randomized phase III trial
comparing adjuvant chemotherapy with S-1 versus surgery alone in
stage II or III gastric cancer. J Clin Oncol. 29:4387–4393. 2011.
View Article : Google Scholar : PubMed/NCBI
|
4
|
Aggarwal BB, Bhardwaj A, Aggarwal RS,
Seeram NP, Shishodia S and Takada Y: Role of resveratrol in
prevention and therapy of cancer: Preclinical and clinical studies.
Anticancer Res. 24:2783–2840. 2004.PubMed/NCBI
|
5
|
Piotrowska H, Kucinska M and Murias M:
Biological activity of piceatannol: Leaving the shadow of
resveratrol. Mutat Res. 750:60–82. 2012. View Article : Google Scholar
|
6
|
Kucinska M, Piotrowska H, Luczak MW,
Mikula-Pietrasik J, Ksiazek K, Wozniak M, Wierzchowski M, Dudka J,
Jäger W and Murias M: Effects of hydroxylated resveratrol analogs
on oxidative stress and cancer cells death in human acute T cell
leukemia cell line: Prooxidative potential of hydroxylated
resveratrol analogs. Chem Biol Interact. 209:96–110. 2014.
View Article : Google Scholar : PubMed/NCBI
|
7
|
Kim JE, Lee JI, Jin DH, Lee WJ, Park GB,
Kim S, Kim YS, Wu TC, Hur DY and Kim D: Sequential treatment of HPV
E6 and E7-expressing TC-1 cells with bortezomib and celecoxib
promotes apoptosis through p-p38 MAPK-mediated downregulation of
cyclin D1 and CDK2. Oncol Rep. 31:2429–2437. 2014.PubMed/NCBI
|
8
|
Zhang J, Wei J, Lu J, Tong Z, Liao B, Yu
B, Zheng F, Huang X, Chen Z, Fang Y, et al: Overexpression of Rab25
contributes to metastasis of bladder cancer through induction of
epithelial- mesenchymal transition and activation of
Akt/GSK-3β/Snail signaling. Carcinogenesis. 34:2401–2408. 2013.
View Article : Google Scholar : PubMed/NCBI
|
9
|
Mirzoeva OK, Hann B, Hom YK, Debnath J,
Aftab D, Shokat K and Korn WM: Autophagy suppression promotes
apoptotic cell death in response to inhibition of the PI3K-mTOR
pathway in pancreatic adenocarcinoma. J Mol Med Berl. 89:877–889.
2011. View Article : Google Scholar : PubMed/NCBI
|
10
|
Yan-nan B, Zhao-yan Y, Li-xi L, Jiang Y,
Qing-jie X and Yong Z: MicroRNA-21 accelerates hepatocyte
proliferation in vitro via PI3K/Akt signaling by targeting PTEN.
Biochem Biophys Res Commun. 443:802–807. 2014. View Article : Google Scholar
|
11
|
Sansal I and Sellers WR: The biology and
clinical relevance of the PTEN tumor suppressor pathway. J Clin
Oncol. 22:2954–2963. 2004. View Article : Google Scholar : PubMed/NCBI
|
12
|
Maehama T and Dixon JE: The tumor
suppressor, PTEN/MMAC1, dephosphorylates the lipid second
messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem.
273:13375–13378. 1998. View Article : Google Scholar : PubMed/NCBI
|
13
|
Lu Y, Lin YZ, LaPushin R, Cuevas B, Fang
X, Yu SX, Davies MA, Khan H, Furui T, Mao M, et al: The
PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and
induces apoptosis and anoikis in breast cancer cells. Oncogene.
18:7034–7045. 1999. View Article : Google Scholar : PubMed/NCBI
|
14
|
Weng L, Brown J and Eng C: PTEN induces
apoptosis and cell cycle arrest through
phosphoinositol-3-kinase/Akt-dependent and -independent pathways.
Hum Mol Genet. 10:237–242. 2001. View Article : Google Scholar : PubMed/NCBI
|
15
|
Louis KS and Siegel AC: Cell viability
analysis using trypan blue: Manual and automated methods. Methods
Mol Biol. 740:7–12. 2011. View Article : Google Scholar : PubMed/NCBI
|
16
|
Yu XJ, Han QB, Wen ZS, Ma L, Gao J and
Zhou GB: Gambogenic acid induces G1 arrest via GSK3β-dependent
cyclin D1 degradation and triggers autophagy in lung cancer cells.
Cancer Lett. 322:185–194. 2012. View Article : Google Scholar : PubMed/NCBI
|
17
|
Riles WL, Erickson J, Nayyar S, Atten MJ,
Attar BM and Holian O: Resveratrol engages selective apoptotic
signals in gastric adenocarcinoma cells. World J Gastroenterol.
12:5628–5634. 2006.PubMed/NCBI
|
18
|
Yang W, Zhang Y, Li Y, Wu Z and Zhu D:
Myostatin induces cyclin D1 degradation to cause cell cycle arrest
through a phosphatidylinositol 3-kinase/AKT/GSK-3 beta pathway and
is antagonized by insulin-like growth factor 1. J Biol Chem.
282:3799–3808. 2007. View Article : Google Scholar
|
19
|
Coupland VH, Allum W, Blazeby JM, Mendall
MA, Hardwick RH, Linklater KM, Møller H and Davies EA: Incidence
and survival of oesophageal and gastric cancer in England between
1998 and 2007, a population-based study. BMC Cancer. 12:112012.
View Article : Google Scholar : PubMed/NCBI
|
20
|
Kunz PL, Gubens M, Fisher GA, Ford JM,
Lichtensztajn DY and Clarke CA: Long-term survivors of gastric
cancer: A California population-based study. J Clin Oncol.
30:3507–3515. 2012. View Article : Google Scholar : PubMed/NCBI
|
21
|
Zheng L, Wu C, Xi P, Zhu M, Zhang L, Chen
S, Li X, Gu J and Zheng Y: The survival and the long-term trends of
patients with gastric cancer in Shanghai, China. BMC Cancer.
14:3002014. View Article : Google Scholar : PubMed/NCBI
|
22
|
Ito Y, Nakayama T, Miyashiro I, Ioka A and
Tsukuma H: Conditional survival for longer-term survivors from
2000–2004 using population-based cancer registry data in Osaka,
Japan. BMC Cancer. 13:3042013. View Article : Google Scholar
|
23
|
Ge J, Liu Y, Li Q, Guo X, Gu L, Ma ZG and
Zhu YP: Resveratrol induces apoptosis and autophagy in T-cell acute
lymphoblastic leukemia cells by inhibiting Akt/mTOR and activating
p38-MAPK. Biomed Environ Sci. 26:902–911. 2013.PubMed/NCBI
|
24
|
Meng LY, Liu HR, Shen Y, Yu YQ and Tao X:
Cochinchina momordica seed extract induces G2/M arrest and
apoptosis in human breast cancer MDA-MB-231 cells by modulating the
PI3K/Akt pathway. Asian Pac J Cancer Prev. 12:3483–3488.
2011.PubMed/NCBI
|
25
|
Zhang F, Liu J and Shi JS:
Anti-inflammatory activities of resveratrol in the brain: Role of
resveratrol in microglial activation. Eur J Pharmacol. 636:1–7.
2010. View Article : Google Scholar : PubMed/NCBI
|
26
|
Orsu P, Murthy BV and Akula A:
Cerebroprotective potential of resveratrol through anti-oxidant and
anti-inflammatory mechanisms in rats. J Neural Transm.
120:1217–1223. 2013. View Article : Google Scholar : PubMed/NCBI
|
27
|
Tomé-Carneiro J, Larrosa M, Yáñez-Gascón
MJ, Dávalos A, Gil-Zamorano J, Gonzálvez M, García-Almagro FJ, Ruiz
Ros JA, Tomás-Barberán FA, Espín JC, et al: One-year
supplementation with a grape extract containing resveratrol
modulates inflammatory-related microRNAs and cytokines expression
in peripheral blood mononuclear cells of type 2 diabetes and
hypertensive patients with coronary artery disease. Pharmacol Res.
72:69–82. 2013. View Article : Google Scholar : PubMed/NCBI
|
28
|
Kauffmann-Zeh A, Rodriguez-Viciana P,
Ulrich E, Gilbert C, Coffer P, Downward J and Evan G: Suppression
of c-Myc-induced apoptosis by Ras signalling through PI(3)K and
PKB. Nature. 385:544–548. 1997. View
Article : Google Scholar : PubMed/NCBI
|
29
|
Liang J and Slingerland JM: Multiple roles
of the PI3K/PKB (Akt) pathway in cell cycle progression. Cell
Cycle. 2:339–345. 2003. View Article : Google Scholar : PubMed/NCBI
|
30
|
Ji Q, Liu X, Fu X, Zhang L, Sui H, Zhou L,
Sun J, Cai J, Qin J, Ren J, et al: Resveratrol inhibits invasion
and metastasis of colorectal cancer cells via MALAT1 mediated
Wnt/β-catenin signal pathway. PLoS One. 8:e787002013. View Article : Google Scholar
|
31
|
Baldin V, Lukas J, Marcote MJ, Pagano M
and Draetta G: Cyclin D1 is a nuclear protein required for cell
cycle progression in G1. Genes Dev. 7:812–821. 1993. View Article : Google Scholar : PubMed/NCBI
|
32
|
Choi YJ, Li X, Hydbring P, Sanda T,
Stefano J, Christie AL, Signoretti S, Look AT, Kung AL, von Boehmer
H, et al: The requirement for cyclin D function in tumor
maintenance. Cancer Cell. 22:438–451. 2012. View Article : Google Scholar : PubMed/NCBI
|
33
|
Chen XL, Ren KH, He HW and Shao RG:
Involvement of PI3K/KT/GSK3beta pathway in tetrandrine-induced G1
arrest and apoptosis. Cancer Biol Ther. 7:1073–1078. 2008.
View Article : Google Scholar : PubMed/NCBI
|
34
|
Pontano LL and Diehl JA: DNA
damage-dependent cyclin D1 proteolysis: GSK3beta holds the smoking
gun. Cell Cycle. 8:824–827. 2009. View Article : Google Scholar : PubMed/NCBI
|
35
|
Ashford AL, Oxley D, Kettle J, Hudson K,
Guichard S, Cook SJ and Lochhead PA: A novel DYRK1B inhibitor AZ191
demonstrates that DYRK1B acts independently of GSK3β to
phosphorylate cyclin D1 at Thr(286), not Thr(288). Biochem J.
457:43–56. 2014. View Article : Google Scholar
|
36
|
Garcia-Echeverria C and Sellers WR: Drug
discovery approaches targeting the PI3K/Akt pathway in cancer.
Oncogene. 27:5511–5526. 2008. View Article : Google Scholar : PubMed/NCBI
|
37
|
Osaki M, Oshimura M and Ito H: PI3K-Akt
pathway: Its functions and alterations in human cancer. Apoptosis.
9:667–676. 2004. View Article : Google Scholar : PubMed/NCBI
|
38
|
Fresno Vara JA, Casado E, de Castro J,
Cejas P, Belda-Iniesta C and González-Barón M: PI3K/Akt signalling
pathway and cancer. Cancer Treat Rev. 30:193–204. 2004. View Article : Google Scholar : PubMed/NCBI
|
39
|
Weng LP, Brown JL and Eng C: PTEN
coordinates G(1) arrest by down-regulating cyclin D1 via its
protein phosphatase activity and up-regulating p27 via its lipid
phosphatase activity in a breast cancer model. Hum Mol Genet.
10:599–604. 2001. View Article : Google Scholar : PubMed/NCBI
|
40
|
Huang W, Chang HY, Fei T, Wu H and Chen
YG: GSK3 beta mediates suppression of cyclin D2 expression by tumor
suppressor PTEN. Oncogene. 26:2471–2482. 2007. View Article : Google Scholar
|
41
|
Zhao H, Yang J, Fan T, Li S and Ren X:
RhoE functions as a tumor suppressor in esophageal squamous cell
carcinoma and modulates the PTEN/PI3K/Akt signaling pathway. Tumour
Biol. 33:1363–1374. 2012. View Article : Google Scholar : PubMed/NCBI
|