1
|
Jemal A, Siegel R, Ward E, Hao Y, Xu J,
Murray T and Thun MJ: Cancer statistics, 2008. CA Cancer J Clin.
58:71–96. 2008. View Article : Google Scholar : PubMed/NCBI
|
2
|
Siegel R, Naishadham D and Jemal A: Cancer
statistics, 2012. CA Cancer J Clin. 62:10–29. 2012. View Article : Google Scholar : PubMed/NCBI
|
3
|
Marwitz S, Depner S, Dvornikov D, Merkle
R, Szczygieł M, Müller-Decker K, Lucarelli P, Wäsch M, Mairbäurl H,
Rabe KF, et al: Downregulation of the TGFβ pseudoreceptor BAMBI in
non-small cell lung cancer enhances TGFβ signaling and invasion.
Cancer Res. 76:3785–3801. 2016. View Article : Google Scholar : PubMed/NCBI
|
4
|
Xie Z and Klionsky DJ: Autophagosome
formation: core machinery and adaptations. Nat Cell Biol.
9:1102–1109. 2007. View Article : Google Scholar : PubMed/NCBI
|
5
|
Mizushima N: Physiological functions of
autophagy. Curr Top Microbiol Immunol. 335:71–84. 2009.PubMed/NCBI
|
6
|
Suzuki K, Kirisako T, Kamada Y, Mizushima
N, Noda T and Ohsumi Y: The pre-autophagosomal structure organized
by concerted functions of APG genes is essential for autophagosome
formation. EMBO J. 20:5971–5981. 2001. View Article : Google Scholar : PubMed/NCBI
|
7
|
Yue Z, Jin S, Yang C, Levine AJ and Heintz
N: Beclin 1, an autophagy gene essential for early embryonic
development, is a haploinsufficient tumor suppressor. Proc Natl
Acad Sci USA. 100:15077–15082. 2003. View Article : Google Scholar : PubMed/NCBI
|
8
|
Son YO, Pratheeshkumar P, Roy RV, Hitron
JA, Wang L, Zhang Z and Shi X: Nrf2/p62 signaling in apoptosis
resistance and its role in cadmium-induced carcinogenesis. J Biol
Chem. 289:28660–28675. 2014. View Article : Google Scholar : PubMed/NCBI
|
9
|
Masuda GO, Yashiro M, Kitayama K, Miki Y,
Kasashima H, Kinoshita H, Morisaki T, Fukuoka T, Hasegawa T,
Sakurai K, et al: Clinicopathological correlations of
autophagy-related proteins LC3, Beclin 1 and p62 in gastric cancer.
Anticancer Res. 36:129–136. 2016.PubMed/NCBI
|
10
|
Deng Q, Wang Z, Wang L, Zhang L, Xiang X,
Wang Z and Chong T: Lower mRNA and protein expression levels of LC3
and Beclin1, markers of autophagy, were correlated with progression
of renal clear cell carcinoma. Jpn J Clin Oncol. 43:1261–1268.
2013. View Article : Google Scholar : PubMed/NCBI
|
11
|
Ding Y, Kim JK, Kim SI, Na HJ, Jun SY, Lee
SJ and Choi ME: TGF-{beta}1 protects against mesangial cell
apoptosis via induction of autophagy. J Biol Chem. 285:37909–37919.
2010. View Article : Google Scholar : PubMed/NCBI
|
12
|
Korah J, Canaff L and Lebrun JJ: The
retinoblastoma tumor suppressor protein (pRb)/E2 promoter binding
factor 1 (E2F1) pathway as a novel mediator of TGFβ-induced
autophagy. J Biol Chem. 291:2043–2054. 2016. View Article : Google Scholar : PubMed/NCBI
|
13
|
Kiyono K, Suzuki HI, Matsuyama H,
Morishita Y, Komuro A, Kano MR, Sugimoto K and Miyazono K:
Autophagy is activated by TGF-beta and potentiates
TGF-beta-mediated growth inhibition in human hepatocellular
carcinoma cells. Cancer Res. 69:8844–8852. 2009. View Article : Google Scholar : PubMed/NCBI
|
14
|
Onichtchouk D, Chen YG, Dosch R, Gawantka
V, Delius H, Massagué J and Niehrs C: Silencing of TGF-beta
signalling by the pseudoreceptor BAMBI. Nature. 401:480–485. 1999.
View Article : Google Scholar : PubMed/NCBI
|
15
|
Seki E, De Minicis S, Osterreicher CH,
Kluwe J, Osawa Y, Brenner DA and Schwabe RF: TLR4 enhances TGF-beta
signaling and hepatic fibrosis. Nat Med. 13:1324–1332. 2007.
View Article : Google Scholar : PubMed/NCBI
|
16
|
Vijaya. Yadav AK: In vitro anthelmintic
assessment of selected phytochemicals against Hymenolepis
diminuta, a zoonotic tapeworm. J Parasit Dis. 40:1082–1086.
2016. View Article : Google Scholar : PubMed/NCBI
|
17
|
Dey YN, Sharma G, Wanjari MM, Kumar D,
Lomash V and Jadhav AD: Beneficial effect of Amorphophallus
paeoniifolius tuber on experimental ulcerative colitis in rats.
Pharm Biol. 55:53–62. 2016. View Article : Google Scholar : PubMed/NCBI
|
18
|
Cheng D, Guo Z and Zhang S: Effect of
β-sitosterol on the expression of HPV E6 and p53 in cervical
carcinoma cells. Contemp Oncol (Pozn). 19:36–42. 2015.PubMed/NCBI
|
19
|
Jo GH, Bögler O, Chwae YJ, Yoo H, Lee SH,
Park JB, Kim YJ, Kim JH and Gwak HS: Radiation-induced autophagy
contributes to cell death and induces apoptosis partly in malignant
glioma cells. Cancer Res Treat. 47:221–241. 2015. View Article : Google Scholar : PubMed/NCBI
|
20
|
Shu CW, Chang HT, Wu CS, Chen CH, Wu S,
Chang HW, Kuo SY, Fu E, Liu PF and Hsieh YD: RelA-mediated BECN1
expression is required for reactive oxygen species-induced
autophagy in oral cancer cells exposed to low-power laser
irradiation. PLoS One. 11:e01605862016. View Article : Google Scholar : PubMed/NCBI
|
21
|
Toge M, Yokoyama S, Kato S, Sakurai H,
Senda K, Doki Y, Hayakawa Y, Yoshimura N and Saiki I: Critical
contribution of MCL-1 in EMT-associated chemo-resistance in A549
non-small cell lung cancer. Int J Oncol. 46:1844–1848.
2015.PubMed/NCBI
|
22
|
Lee JG, Shin JH, Shim HS, Lee CY, Kim DJ,
Kim YS and Chung KY: Autophagy contributes to the chemo-resistance
of non-small cell lung cancer in hypoxic conditions. Respir Res.
16:1382015. View Article : Google Scholar : PubMed/NCBI
|
23
|
Ju LL, Zhao CY, Ye KF, Yang H and Zhang J:
Expression and clinical implication of Beclin1, HMGB1, p62,
survivin, BRCA1 and ERCC1 in epithelial ovarian tumor tissues. Eur
Rev Med Pharmacol Sci. 20:1993–2003. 2016.PubMed/NCBI
|
24
|
Jiang K, Liu M, Lin G, Mao B, Cheng W, Liu
H, Gal J, Zhu H, Yuan Z, Deng W, et al: Tumor suppressor Spred2
interaction with LC3 promotes autophagosome maturation and induces
autophagy-dependent cell death. Oncotarget. 7:25652–25667.
2016.PubMed/NCBI
|
25
|
Ghavami S, Cunnington RH, Gupta S, Yeganeh
B, Filomeno KL, Freed DH, Chen S, Klonisch T, Halayko AJ, Ambrose
E, et al: Autophagy is a regulator of TGF-β1-induced fibrogenesis
in primary human atrial myofibroblasts. Cell Death Dis.
6:e16962015. View Article : Google Scholar : PubMed/NCBI
|
26
|
Ding Y, Kim S, Lee SY, Koo JK, Wang Z and
Choi ME: Autophagy regulates TGF-β expression and suppresses kidney
fibrosis induced by unilateral ureteral obstruction. J Am Soc
Nephrol. 25:2835–2846. 2014. View Article : Google Scholar : PubMed/NCBI
|
27
|
Pan CC, Kumar S, Shah N, Bloodworth JC,
Hawinkels LJ, Mythreye K, Hoyt DG and Lee NY: Endoglin regulation
of Smad2 function mediates Beclin1 expression and endothelial
autophagy. J Biol Chem. 290:14884–14892. 2015. View Article : Google Scholar : PubMed/NCBI
|
28
|
Guido C, Whitaker-Menezes D, Capparelli C,
Balliet R, Lin Z, Pestell RG, Howell A, Aquila S, Andò S,
Martinez-Outschoorn U, et al: Metabolic reprogramming of
cancer-associated fibroblasts by TGF-β drives tumor growth:
connecting TGF-β signaling with ‘Warburg-like’ cancer metabolism
and L-lactate production. Cell Cycle. 11:3019–3035. 2012.
View Article : Google Scholar : PubMed/NCBI
|
29
|
Khin SS, Kitazawa R, Win N, Aye TT, Mori
K, Kondo T and Kitazawa S: BAMBI gene is epigenetically silenced in
subset of high-grade bladder cancer. Int J Cancer. 125:328–338.
2009. View Article : Google Scholar : PubMed/NCBI
|
30
|
Jiang Z, Guerrero-Netro HM, Juengel JL and
Price CA: Divergence of intracellular signaling pathways and early
response genes of two closely related fibroblast growth factors,
FGF8 and FGF18, in bovine ovarian granulosa cells. Mol Cell
Endocrinol. 375:97–105. 2013. View Article : Google Scholar : PubMed/NCBI
|
31
|
Shoja MH, Reddy ND, Nayak PG, Srinivasan
KK and Rao CM: Glycosmis pentaphylla (Retz.) DC arrests cell
cycle and induces apoptosis via caspase-3/7 activation in breast
cancer cells. J Ethnopharmacol. 168:50–60. 2015. View Article : Google Scholar : PubMed/NCBI
|
32
|
Sayeed Bin MS and Ameen SS:
Beta-sitosterol: a promising but orphan nutraceutical to fight
against cancer. Nutr Cancer. 67:1214–1220. 2015.PubMed/NCBI
|
33
|
Baskar AA, Al Numair KS, Gabriel Paulraj
M, Alsaif MA, Muamar MA and Ignacimuthu S: β-Sitosterol prevents
lipid peroxidation and improves antioxidant status and
histoarchitecture in rats with 1,2-dimethylhydrazine-induced colon
cancer. J Med Food. 15:335–343. 2012. View Article : Google Scholar : PubMed/NCBI
|
34
|
Yu Y, Bo Z, Chao H and Minghua Z: A study
on the anticancer activity of ethanol extract of Aristolochia
mollissima Hance on osteosarcoma HOS cells. Afr J Tradit
Complement Altern Med. 10:551–554. 2013. View Article : Google Scholar : PubMed/NCBI
|
35
|
Li C and Wang MH: Aristolochia
debilis Sieb. et Zucc. induces apoptosis and reactive oxygen
species in the HT-29 human colon cancer cell line. Cancer Biother
Radiopharm. 28:717–724. 2013. View Article : Google Scholar : PubMed/NCBI
|
36
|
Sook SH, Lee HJ, Kim JH, Sohn EJ, Jung JH,
Kim B, Kim JH, Jeong SJ and Kim SH: Reactive oxygen
species-mediated activation of AMP-activated protein kinase and
c-Jun N-terminal kinase plays a critical role in
beta-sitosterol-induced apoptosis in multiple myeloma U266 cells.
Phytother Res. 28:387–394. 2014. View Article : Google Scholar : PubMed/NCBI
|
37
|
Akhurst RJ and Derynck R: TGF-beta
signaling in cancer - a double-edged sword. Trends Cell Biol.
11:S44–S51. 2001. View Article : Google Scholar : PubMed/NCBI
|
38
|
Kumai T, Oikawa K, Aoki N, Kimura S,
Harabuchi Y, Celis E and Kobayashi H: Tumor-derived TGF-beta and
prostaglandin E2 attenuate anti-tumor immune responses in head and
neck squamous cell carcinoma treated with EGFR inhibitor. J Transl
Med. 12:2652014. View Article : Google Scholar : PubMed/NCBI
|
39
|
Moustakas A and Heldin CH: The regulation
of TGFbeta signal transduction. Development. 136:3699–3714. 2009.
View Article : Google Scholar : PubMed/NCBI
|
40
|
Chen Y, Zou L, Zhang Y, Chen Y, Xing P,
Yang W, Li F, Ji X, Liu F and Lu X: Transforming growth factor-β1
and α-smooth muscle actin in stromal fibroblasts are associated
with a poor prognosis in patients with clinical stage I–IIIA
nonsmall cell lung cancer after curative resection. Tumour Biol.
35:6707–6713. 2014. View Article : Google Scholar : PubMed/NCBI
|
41
|
Yang H, Wang L, Zhao J, Chen Y, Lei Z, Liu
X, Xia W, Guo L and Zhang HT: TGF-β-activated SMAD3/4 complex
transcriptionally upregulates N-cadherin expression in non-small
cell lung cancer. Lung Cancer. 87:249–257. 2015. View Article : Google Scholar : PubMed/NCBI
|
42
|
Zu L, Xue Y, Wang J, Fu Y, Wang X, Xiao G,
Hao M, Sun X, Wang Y, Fu G, et al: The feedback loop between
miR-124 and TGF-β pathway plays a significant role in non-small
cell lung cancer metastasis. Carcinogenesis. 37:333–343. 2016.
View Article : Google Scholar : PubMed/NCBI
|
43
|
Shangguan L, Ti X, Krause U, Hai B, Zhao
Y, Yang Z and Liu F: Inhibition of TGF-β/Smad signaling by BAMBI
blocks differentiation of human mesenchymal stem cells to
carcinoma-associated fibroblasts and abolishes their protumor
effects. Stem Cells. 30:2810–2819. 2012. View Article : Google Scholar : PubMed/NCBI
|
44
|
Fan Y, Li X, Xiao W, Fu J, Harris RC,
Lindenmeyer M, Cohen CD, Guillot N, Baron MH, Wang N, et al: BAMBI
elimination enhances alternative TGF-β signaling and glomerular
dysfunction in diabetic mice. Diabetes. 64:2220–2233. 2015.
View Article : Google Scholar : PubMed/NCBI
|