1
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI
|
2
|
Chang YY, Lin PC, Lin HH, Lin JK, Chen WS,
Jiang JK, Yang SH, Liang WY and Chang SC: Mutation spectra of RAS
gene family in colorectal cancer. Am J Surg. 212:537–544.e3. 2016.
View Article : Google Scholar : PubMed/NCBI
|
3
|
Pollock CB, Shirasawa S, Sasazuki T, Kolch
W and Dhillon AS: Oncogenic K-RAS is required to maintain changes
in cytoskeletal organization, adhesion, and motility in colon
cancer cells. Cancer Res. 65:1244–1250. 2005. View Article : Google Scholar : PubMed/NCBI
|
4
|
Bäumer S, Bäumer N, Appel N, Terheyden L,
Fremerey J, Schelhaas S, Wardelmann E, Buchholz F, Berdel WE and
Müller-Tidow C: Antibody-mediated delivery of anti-KRAS-siRNA in
vivo overcomes therapy resistance in colon cancer. Clin Cancer Res.
21:1383–1394. 2015. View Article : Google Scholar : PubMed/NCBI
|
5
|
Pereira AA, Rego JF, Morris V, Overman MJ,
Eng C, Garrett CR, Boutin AT, Ferrarotto R, Lee M, Jiang ZQ, et al:
Association between KRAS mutation and lung metastasis in advanced
colorectal cancer. Br J Cancer. 112:424–428. 2015. View Article : Google Scholar : PubMed/NCBI
|
6
|
Feng Y, Bommer GT, Zhao J, Green M, Sands
E, Zhai Y, Brown K, Burberry A, Cho KR and Fearon ER: Mutant KRAS
promotes hyperplasia and alters differentiation in the colon
epithelium but does not expand the presumptive stem cell pool.
Gastroenterology. 141:11003–1013.e1. –10. 2011. View Article : Google Scholar
|
7
|
Yoshida M, Taguchi A, Kawana K, Adachi K,
Kawata A, Ogishima J, Nakamura H, Fujimoto A, Sato M, Inoue T, et
al: Modification of the tumor microenvironment in KRAS or
c-MYC-induced ovarian cancer-associated peritonitis. PLoS One.
11:e01603302016. View Article : Google Scholar : PubMed/NCBI
|
8
|
Sparmann A and Bar-Sagi D: Ras-induced
interleukin-8 expression plays a critical role in tumor growth and
angiogenesis. Cancer Cell. 6:447–458. 2004. View Article : Google Scholar : PubMed/NCBI
|
9
|
Pylayeva-Gupta Y, Lee KE, Hajdu CH, Miller
G and Bar-Sagi D: Oncogenic Kras-induced GM-CSF production promotes
the development of pancreatic neoplasia. Cancer Cell. 21:836–847.
2012. View Article : Google Scholar : PubMed/NCBI
|
10
|
Quante M, Varga J, Wang TC and Greten FR:
The gastrointestinal tumor microenvironment. Gastroenterology.
145:63–78. 2013. View Article : Google Scholar : PubMed/NCBI
|
11
|
Augsten M, Hägglöf C, Peña C and Ostman A:
A digest on the role of the tumor microenvironment in
gastrointestinal cancers. Cancer Microenviron. 3:167–176. 2010.
View Article : Google Scholar : PubMed/NCBI
|
12
|
Hanahan D and Coussens LM: Accessories to
the crime: Functions of cells recruited to the tumor
microenvironment. Cancer Cell. 21:309–322. 2012. View Article : Google Scholar : PubMed/NCBI
|
13
|
Tahara E: Abnormal growth factor/cytokine
network in gastric cancer. Cancer Microenviron. 1:85–91. 2008.
View Article : Google Scholar : PubMed/NCBI
|
14
|
Avgustinova A, Iravani M, Robertson D,
Fearns A, Gao Q, Klingbeil P, Hanby AM, Speirs V, Sahai E, Calvo F,
et al: Tumour cell-derived Wnt7a recruits and activates fibroblasts
to promote tumour aggressiveness. Nat Commun. 7:103052016.
View Article : Google Scholar : PubMed/NCBI
|
15
|
Chivukula RR, Shi G, Acharya A, Mills EW,
Zeitels LR, Anandam JL, Abdelnaby AA, Balch GC, Mansour JC, Yopp
AC, et al: An essential mesenchymal function for miR-143/145 in
intestinal epithelial regeneration. Cell. 157:1104–1116. 2014.
View Article : Google Scholar : PubMed/NCBI
|
16
|
Powell DW, Adegboyega PA, Di Mari JF and
Mifflin RC: Epithelial cells and their neighbors I. Role of
intestinal myofibroblasts in development, repair, and cancer. Am J
Physiol Gastrointest Liver Physiol. 289:G2–G7. 2005. View Article : Google Scholar : PubMed/NCBI
|
17
|
Vermeulen L, De Sousa E, Melo F, van der
Heijden M, Cameron K, de Jong JH, Borovski T, Tuynman JB, Todaro M,
Merz C, Rodermond H, et al: Wnt activity defines colon cancer stem
cells and is regulated by the microenvironment. Nat Cell Biol.
12:468–476. 2010. View
Article : Google Scholar : PubMed/NCBI
|
18
|
Murata T, Mizushima H, Chinen I, Moribe H,
Yagi S, Hoffman RM, Kimura T, Yoshino K, Ueda Y, Enomoto T, et al:
HB-EGF and PDGF mediate reciprocal interactions of carcinoma cells
with cancer-associated fibroblasts to support progression of
uterine cervical cancers. Cancer Res. 71:6633–6642. 2011.
View Article : Google Scholar : PubMed/NCBI
|
19
|
Zhu L, Cheng X, Ding Y, Shi J, Jin H, Wang
H, Wu Y, Ye J, Lu Y, Wang TC, et al: Bone marrow-derived
myofibroblasts promote colon tumorigenesis through the
IL-6/JAK2/STAT3 pathway. Cancer Lett. 343:80–89. 2014. View Article : Google Scholar : PubMed/NCBI
|
20
|
Clapéron A, Mergey M, Aoudjehane L,
Ho-Bouldoires TH, Wendum D, Prignon A, Merabtene F, Firrincieli D,
Desbois-Mouthon C, Scatton O, et al: Hepatic myofibroblasts promote
the progression of human cholangiocarcinoma through activation of
epidermal growth factor receptor. Hepatology. 58:2001–2011. 2013.
View Article : Google Scholar : PubMed/NCBI
|
21
|
Lewis MP, Lygoe KA, Nystrom ML, Anderson
WP, Speight PM, Marshall JF and Thomas GJ: Tumour-derived TGF-beta1
modulates myofibroblast differentiation and promotes
HGF/SF-dependent invasion of squamous carcinoma cells. Br J Cancer.
90:822–832. 2004. View Article : Google Scholar : PubMed/NCBI
|
22
|
Martin M, Wei H and Lu T: Targeting
microenvironment in cancer therapeutics. Oncotarget. 7:52575–52583.
2016.PubMed/NCBI
|
23
|
Kawasaki H, Ohama T, Hori M and Sato K:
Establishment of mouse intestinal myofibroblast cell lines. World J
Gastroenterol. 19:2629–2637. 2013. View Article : Google Scholar : PubMed/NCBI
|
24
|
Iwamoto T, Yamada K, Shimizu M and Totsuka
M: Establishment of intestinal epithelial cell lines from adult
mouse small and large intestinal crypts. Biosci Biotechnol Biochem.
75:925–929. 2011. View Article : Google Scholar : PubMed/NCBI
|
25
|
Yabe R, Miura A, Usui T, Mudrak I, Ogris
E, Ohama T and Sato K: Protein phosphatase methyl-esterase PME-1
protects protein phosphatase 2A from ubiquitin/proteasome
degradation. PLoS One. 10:e01452262015. View Article : Google Scholar : PubMed/NCBI
|
26
|
Fujiwara N, Kawasaki H, Yabe R,
Christensen DJ, Vitek MP, Mizuno T, Sato K and Ohama T: A potential
therapeutic application of SET/I2PP2A inhibitor OP449 for canine
T-cell lymphoma. J Vet Med Sci. 75:349–354. 2013. View Article : Google Scholar : PubMed/NCBI
|
27
|
Usui T, Morita T, Okada M and Yamawaki H:
Histone deacetylase 4 controls neointimal hyperplasia via
stimulating proliferation and migration of vascular smooth muscle
cells. Hypertension. 63:397–403. 2014. View Article : Google Scholar : PubMed/NCBI
|
28
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
29
|
Le Rolle AF, Chiu TK, Zeng Z, Shia J,
Weiser MR, Paty PB and Chiu VK: Oncogenic KRAS activates an
embryonic stem cell-like program in human colon cancer initiation.
Oncotarget. 7:2159–2174. 2016.PubMed/NCBI
|
30
|
Hammond DE, Mageean CJ, Rusilowicz EV,
Wickenden JA, Clague MJ and Prior IA: Differential reprogramming of
isogenic colorectal cancer cells by distinct activating KRAS
mutations. J Proteome Res. 14:1535–1546. 2015. View Article : Google Scholar : PubMed/NCBI
|
31
|
Vinante F and Rigo A: Heparin-binding
epidermal growth factor-like growth factor/diphtheria toxin
receptor in normal and neoplastic hematopoiesis. Toxins (Basel).
5:1180–1201. 2013. View Article : Google Scholar : PubMed/NCBI
|
32
|
Rao GH, Liu HM, Li BW, Hao JJ, Yang YL,
Wang MR, Wang XH, Wang J, Jin HJ, Du L, et al: Establishment of a
human colorectal cancer cell line P6C with stem cell properties and
resistance to chemotherapeutic drugs. Acta Pharmacol Sin.
34:793–804. 2013. View Article : Google Scholar : PubMed/NCBI
|
33
|
Rowehl RA, Burke S, Bialkowska AB, Pettet
DW III, Rowehl L, Li E, Antoniou E, Zhang Y, Bergamaschi R, Shroyer
KR, et al: Establishment of highly tumorigenic human colorectal
cancer cell line (CR4) with properties of putative cancer stem
cells. PLoS One. 9:e990912014. View Article : Google Scholar : PubMed/NCBI
|
34
|
Hung CF, Rohani MG, Lee SS, Chen P and
Schnapp LM: Role of IGF-1 pathway in lung fibroblast activation.
Respir Res. 14:1022013. View Article : Google Scholar : PubMed/NCBI
|
35
|
Theiss AL, Simmons JG, Jobin C and Lund
PK: Tumor necrosis factor (TNF) alpha increases collagen
accumulation and proliferation in intestinal myofibroblasts via TNF
receptor 2. J Biol Chem. 280:36099–36109. 2005. View Article : Google Scholar : PubMed/NCBI
|
36
|
Jobson TM, Billington CK and Hall IP:
Regulation of proliferation of human colonic subepithelial
myofibroblasts by mediators important in intestinal inflammation. J
Clin Invest. 101:2650–2657. 1998. View
Article : Google Scholar : PubMed/NCBI
|
37
|
Yotsumoto F, Tokunaga E, Oki E, Maehara Y,
Yamada H, Nakajima K, Nam SO, Miyata K, Koyanagi M, Doi K, et al:
Molecular hierarchy of heparin-binding EGF-like growth
factor-regulated angiogenesis in triple-negative breast cancer. Mol
Cancer Res. 11:506–517. 2013. View Article : Google Scholar : PubMed/NCBI
|
38
|
Yahata Y, Shirakata Y, Tokumaru S, Yang L,
Dai X, Tohyama M, Tsuda T, Sayama K, Iwai M, Horiuchi M, et al: A
novel function of angiotensin II in skin wound healing. Induction
of fibroblast and keratinocyte migration by angiotensin II via
heparin-binding epidermal growth factor (EGF)-like growth
factor-mediated EGF receptor transactivation. J Biol Chem.
281:13209–13216. 2006. View Article : Google Scholar : PubMed/NCBI
|
39
|
Kim JM, Bak EJ, Chang JY, Kim ST, Park WS,
Yoo YJ and Cha JH: Effects of HB-EGF and epiregulin on wound
healing of gingival cells in vitro. Oral Dis. 17:785–793. 2011.
View Article : Google Scholar : PubMed/NCBI
|
40
|
Faria JA, de Andrade C, Goes AM, Rodrigues
MA and Gomes DA: Effects of different ligands on epidermal growth
factor receptor (EGFR) nuclear translocation. Biochem Biophys Res
Commun. 478:39–45. 2016. View Article : Google Scholar : PubMed/NCBI
|
41
|
Kastanis GJ, Hernandez-Nazara Z, Nieto N,
Rincón-Sanchez AR, Popratiloff A, Dominguez-Rosales JA, Lechuga CG
and Rojkind M: The role of dystroglycan in PDGF-BB-dependent
migration of activated hepatic stellate cells/myofibroblasts. Am J
Physiol Gastrointest Liver Physiol. 301:G464–G474. 2011. View Article : Google Scholar : PubMed/NCBI
|
42
|
Shi H, Lin B, Huang Y, Wu J, Zhang H, Lin
C, Wang Z, Zhu J, Zhao Y, Fu X, et al: Basic fibroblast growth
factor promotes melanocyte migration via activating
PI3K/Akt-Rac1-FAK-JNK and ERK signaling pathways. IUBMB Life.
68:735–747. 2016. View Article : Google Scholar : PubMed/NCBI
|
43
|
Chun J and Kim YS: Platycodin D inhibits
migration, invasion, and growth of MDA-MB-231 human breast cancer
cells via suppression of EGFR-mediated Akt and MAPK pathways. Chem
Biol Interact. 205:212–221. 2013. View Article : Google Scholar : PubMed/NCBI
|
44
|
Ong BA, Vega KJ and Houchen CW: Intestinal
stem cells and the colorectal cancer microenvironment. World J
Gastroenterol. 20:1898–1909. 2014. View Article : Google Scholar : PubMed/NCBI
|