1
|
Wang SS, Cen X, Liang XH and Tang YL:
Macrophage migration inhibitory factor: A potential driver and
biomarker for head and neck squamous cell carcinoma. Oncotarget.
8:10650–10661. 2017.PubMed/NCBI
|
2
|
Kang H, Kiess A and Chung CH: Emerging
biomarkers in head and neck cancer in the era of genomics. Nat Rev
Clin Oncol. 12:11–26. 2015. View Article : Google Scholar : PubMed/NCBI
|
3
|
Birt DF and Bresnick E: Chemoprevention by
nonnutrient components of vegetables and fruits. Springer US;
1991
|
4
|
Aggarwal BB and Shishodia S: Molecular
targets of dietary agents for prevention and therapy of cancer.
Biochem Pharmacol. 71:1397–1421. 2006. View Article : Google Scholar : PubMed/NCBI
|
5
|
Wijeratne SS, Abou-Zaid MM and Shahidi F:
Antioxidant polyphenols in almond and its coproducts. J Agric Food
Chem. 54:312–318. 2006. View Article : Google Scholar : PubMed/NCBI
|
6
|
Brown J, O'Prey J and Harrison PR:
Enhanced sensitivity of human oral tumours to the flavonol, morin,
during cancer progression: Involvement of the Akt and stress kinase
pathways. Carcinogenesis. 24:171–177. 2003. View Article : Google Scholar : PubMed/NCBI
|
7
|
Sivaramakrishnan V and Niranjali DS: Morin
regulates the expression of NF-kappaB-p65, COX-2 and matrix
metalloproteinases in diethylnitrosamine induced rat hepatocellular
carcinoma. Chem Biol Interact. 180:353–359. 2009. View Article : Google Scholar : PubMed/NCBI
|
8
|
Sivaramakrishnan V and Devaraj SN: Morin
fosters apoptosis in experimental hepatocellular carcinogenesis
model. Chem Biol Interact. 183:284–292. 2010. View Article : Google Scholar : PubMed/NCBI
|
9
|
Madankumar P, Naveenkumar P, Manikandan S,
Devaraj H and Niranjalidevaraj S: Morin ameliorates chemically
induced liver fibrosis in vivo and inhibits stellate cell
proliferation in vitro by suppressing Wnt/β-catenin signaling.
Toxicol Appl Pharmacol. 277:210–220. 2014. View Article : Google Scholar : PubMed/NCBI
|
10
|
Madankumar P, Naveenkumar P, Devaraj H and
Niranjalidevaraj S: Morin, a dietary flavonoid, exhibits
anti-fibrotic effect and induces apoptosis of activated hepatic
stellate cells by suppressing canonical NF-κB signaling. Biochimie.
110:107–118. 2015. View Article : Google Scholar : PubMed/NCBI
|
11
|
Kuo HM, Chang LS, Lin YL, Lu HF, Yang JS,
Lee JH and Chung JG: Morin inhibits the growth of human leukemia
HL-60 cells via cell cycle arrest and induction of apoptosis
through mitochondria dependent pathway. Anticancer Res. 27:395–405.
2007.PubMed/NCBI
|
12
|
Gupta SC, Phromnoi K and Aggarwal BB:
Morin inhibits STAT3 tyrosine 705 phosphorylation in tumor cells
through activation of protein tyrosine phosphatase SHP1. Biochem
Pharmacol. 85:898–912. 2013. View Article : Google Scholar : PubMed/NCBI
|
13
|
Saucedo LJ and Edgar BA: Filling out the
Hippo pathway. Nat Rev Mol Cell Biol. 8:613–621. 2007. View Article : Google Scholar : PubMed/NCBI
|
14
|
Bichsel SJ, Tamaskovic R, Stegert MR and
Hemmings BA: Mechanism of activation of NDR (nuclear Dbf2-related)
protein kinase by the hMOB1 protein. J Biol Chem. 279:35228–35235.
2004. View Article : Google Scholar : PubMed/NCBI
|
15
|
Pan D: The hippo signaling pathway in
development and cancer. Dev Cell. 19:491–505. 2010. View Article : Google Scholar : PubMed/NCBI
|
16
|
Oka T, Mazack V and Sudol M: Mst2 and Lats
kinases regulate apoptotic function of yes kinase-associated
protein (YAP). J Biol Chem. 283:27534–27546. 2008. View Article : Google Scholar : PubMed/NCBI
|
17
|
Huang J, Wu S, Barrera J, Matthews K and
Pan D: The hippo signaling pathway coordinately regulates cell
proliferation and apoptosis by inactivating Yorkie, the
Drosophila homolog of YAP. Cell. 122:421–434. 2005.
View Article : Google Scholar : PubMed/NCBI
|
18
|
Yu FX and Guan KL: The Hippo pathway:
Regulators and regulations. Genes Dev. 27:355–371. 2013. View Article : Google Scholar : PubMed/NCBI
|
19
|
Halder G and Johnson RL: Hippo signaling:
Growth control and beyond. Development. 138:9–22. 2011. View Article : Google Scholar : PubMed/NCBI
|
20
|
Zhao B, Tumaneng K and Guan KL: The Hippo
pathway in organ size control, tissue regeneration and stem cell
self-renewal. Nat Cell Biol. 13:877–883. 2011. View Article : Google Scholar : PubMed/NCBI
|
21
|
Zeng Q and Hong W: The emerging role of
the hippo pathway in cell contact inhibition, organ size control,
and cancer development in mammals. Cancer Cell. 13:188–192. 2008.
View Article : Google Scholar : PubMed/NCBI
|
22
|
Yu FX, Zhao B and Guan KL: Hippo pathway
in organ size control, tissue homeostasis, and cancer. Cell.
163:811–828. 2015. View Article : Google Scholar : PubMed/NCBI
|
23
|
Cordenonsi M, Zanconato F, Azzolin L,
Forcato M, Rosato A, Frasson C, Inui M, Montagner M, Parenti AR,
Poletti A, et al: The Hippo transducer TAZ confers cancer stem
cell-related traits on breast cancer cells. Cell. 147:759–772.
2011. View Article : Google Scholar : PubMed/NCBI
|
24
|
Overholtzer M, Zhang J, Smolen GA, Muir B,
Li W, Sgroi DC, Deng CX, Brugge JS and Haber DA: Transforming
properties of YAP, a candidate oncogene on the chromosome 11q22
amplicon. Proc Natl Acad Sci USA. 103:12405–12410. 2006. View Article : Google Scholar : PubMed/NCBI
|
25
|
Steinhardt AA, Gayyed MF, Klein AP, Dong
J, Maitra A, Pan D, Montgomery EA and Anders RA: Expression of
Yes-associated protein in common solid tumors. Hum Pathol.
39:1582–1589. 2008. View Article : Google Scholar : PubMed/NCBI
|
26
|
Fernandez-L A, Northcott PA, Dalton J,
Fraga C, Ellison D, Angers S, Taylor MD and Kenney AM: YAP1 is
amplified and up-regulated in hedgehog-associated medulloblastomas
and mediates Sonic hedgehog-driven neural precursor proliferation.
Genes Dev. 23:2729–2741. 2009. View Article : Google Scholar : PubMed/NCBI
|
27
|
Song Y, Li L, Ou Y, Gao Z, Li E, Li X,
Zhang W, Wang J, Xu L, Zhou Y, et al: Identification of genomic
alterations in oesophageal squamous cell cancer. Nature. 509:91–95.
2014. View Article : Google Scholar : PubMed/NCBI
|
28
|
Mohseni M, Sun J, Lau A, Curtis S,
Goldsmith J, Fox VL, Wei C, Frazier M, Samson O, Wong KK, et al: A
genetic screen identifies an LKB1-MARK signalling axis controlling
the Hippo-YAP pathway. Nat Cell Biol. 16:108–117. 2014. View Article : Google Scholar : PubMed/NCBI
|
29
|
Perumal N, Perumal M, Kannan A, Subramani
K, Halagowder D and Sivasithamparam N: Morin impedes Yap nuclear
translocation and fosters apoptosis through suppression of
Wnt/β-catenin and NF-κB signaling in Mst1 overexpressed HepG2
cells. Exp Cell Res. 15:124–141. 2017. View Article : Google Scholar
|
30
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2−ΔΔCT method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
31
|
Gutiérrez RM, Mitchell S and Solis RV:
Psidium guajava: A review of its traditional uses,
phytochemistry and pharmacology. J Ethnopharmacol. 117:1–27. 2008.
View Article : Google Scholar : PubMed/NCBI
|
32
|
Jin H, Lee WS, Eun SY, Jung JH, Park HS,
Kim G, Choi YH, Ryu CH, Jung JM, Hong SC, et al: Morin, a flavonoid
from Moraceae, suppresses growth and invasion of the highly
metastatic breast cancer cell line MDA-MB-231 partly through
suppression of the Akt pathway. Int J Oncol. 45:1629–1637. 2014.
View Article : Google Scholar : PubMed/NCBI
|
33
|
Park C, Lee WS, Go SI, Nagappan A, Han MH,
Hong SH, Kim GS, Kim GY, Kwon TK, Ryu CH, et al: Morin, a flavonoid
from moraceae, induces apoptosis by induction of BAD protein in
human leukemic cells. Int J Mol Sci. 16:645–659. 2014. View Article : Google Scholar : PubMed/NCBI
|
34
|
Hu J, Guo X and Yang L: Morin inhibits
proliferation and self-renewal of CD133+ melanoma cells
by upregulating miR-216a. J Pharmacol Sci. 136:114–120. 2018.
View Article : Google Scholar : PubMed/NCBI
|
35
|
Hoque A and Xu XC: Basic and translational
research on dietary phytochemicals and cancer prevention. Targeting
Cellular Signaling for Cancer Prevention and Therapy by
Phytochemicals. 127–156. 2013. View Article : Google Scholar
|
36
|
Singh MP, Chauhan AK and Sun CK: Morin
hydrate ameliorates cisplatin-induced ER stress, inflammation and
autophagy in HEK-293 cells and mice kidney via PARP-1 regulation.
Int Immunopharmacol. 56:156–167. 2018. View Article : Google Scholar : PubMed/NCBI
|
37
|
Thangarajan S, Vedagiri A, Somasundaram S,
Sakthimanogaran R and Murugesan M: Neuroprotective effect of morin
on lead acetate-induced apoptosis by preventing cytochrome c
translocation via regulation of Bax/Bcl-2 ratio. Neurotoxicol
Teratol. 66:35–45. 2018. View Article : Google Scholar : PubMed/NCBI
|
38
|
Ling P, Lu TJ, Yuan CJ and Lai MD:
Biosignaling of mammalian Ste20-related kinases. Cell Signal.
20:1237–1247. 2008. View Article : Google Scholar : PubMed/NCBI
|
39
|
Song H, Mak KK, Topol L, Yun K, Hu J,
Garrett L, Chen Y, Park O, Chang J, Simpson RM, et al: Mammalian
Mst1 and Mst2 kinases play essential roles in organ size control
and tumor suppression. Proc Natl Acad Sci USA. 107:1431–1436. 2010.
View Article : Google Scholar : PubMed/NCBI
|
40
|
Xie M, Zhang L, He CS, Hou JH, Lin SX, Hu
ZH, Xu F and Zhao HY: Prognostic significance of TAZ expression in
resected non-small cell lung cancer. J Thorac Oncol. 7:799–807.
2012. View Article : Google Scholar : PubMed/NCBI
|
41
|
Su LL, Ma WX, Yuan JF, Shao Y, Xiao W and
Jiang SJ: Expression of Yes-associated protein in non-small cell
lung cancer and its relationship with clinical pathological
factors. Chin Med J. 125:4003–4008. 2012.PubMed/NCBI
|
42
|
Noguchi S, Saito A, Horie M, Mikami Y,
Suzuki HI, Morishita Y, Ohshima M, Abiko Y, Mattsson JS, König H,
et al: An integrative analysis of the tumorigenic role of TAZ in
human non-small cell lung cancer. Clin Cancer Res. 20:4660–4672.
2014. View Article : Google Scholar : PubMed/NCBI
|
43
|
Perra A, Kowalik MA, Ghiso E,
Ledda-Columbano GM, Di Tommaso L, Angioni MM, Raschioni C, Testore
E, Roncalli M, Giordano S, et al: YAP activation is an early event
and a potential therapeutic target in liver cancer development. J
Hepatol. 61:1088–1096. 2014. View Article : Google Scholar : PubMed/NCBI
|
44
|
Morvaridi S, Dhall D, Greene MI, Pandol SJ
and Wang Q: Role of YAP and TAZ in pancreatic ductal adenocarcinoma
and in stellate cells associated with cancer and chronic
pancreatitis. Sci Rep. 5:167592015. View Article : Google Scholar : PubMed/NCBI
|
45
|
Diep CH, Zucker KM, Hostetter G, Watanabe
A, Hu C, Munoz RM, Von Hoff DD and Han H: Down-regulation of yes
associated protein 1 expression reduces cell proliferation and
clonogenicity of pancreatic cancer cells. PLoS One. 7:e327832012.
View Article : Google Scholar : PubMed/NCBI
|
46
|
Zhang W, Nandakumar N, Shi Y, Manzano M,
Smith A, Graham G, Gupta S, Vietsch EE, Laughlin SZ, Wadhwa M, et
al: Downstream of mutant KRAS, the transcription regulator YAP is
essential for neoplastic progression to pancreatic ductal
adenocarcinoma. Sci Signal. 7:ra422014. View Article : Google Scholar : PubMed/NCBI
|