1
|
Nault JC, Sutter O, Nahon P, Ganne-Carrié
N and Séror O: Percutaneous treatment of hepatocellular carcinoma:
State of the art and innovations. J Hepatol. Oct 13–2017.(Epub
ahead of print).
|
2
|
Kim E, Kim D, Lee JS, Yoe J, Park J, Kim
CJ, Jeong D, Kim S and Lee Y: Capicua suppresses hepatocellular
carcinoma progression by controlling ETV4-MMP1 axis. Hepatology.
67:2287–2301. 2018. View Article : Google Scholar : PubMed/NCBI
|
3
|
Shen Q, Eun JW, Lee K, Kim HS, Yang HD,
Kim SY, Lee EK, Kim T, Kang K, Kim S, et al: BANF1, PLOD3, SF3B4 as
early-stage cancer decision markers and drivers of hepatocellular
carcinoma. Hepatology. 67:1360–1377. 2018. View Article : Google Scholar : PubMed/NCBI
|
4
|
Finn RS, Zhu AX, Farah W, Almasri J, Zaiem
F, Prokop LJ, Murad MH and Mohammed K: Therapies for advanced stage
hepatocellular carcinoma with macrovascular invasion or metastatic
disease: A systematic review and meta-analysis. Hepatology.
67:422–435. 2018. View Article : Google Scholar : PubMed/NCBI
|
5
|
Dietrich P, Koch A, Fritz V, Hartmann A,
Bosserhoff AK and Hellerbrand C: Wild type Kirsten rat sarcoma is a
novel microRNA-622-regulated therapeutic target for hepatocellular
carcinoma and contributes to sorafenib resistance. Gut.
67:1328–1341. 2018. View Article : Google Scholar : PubMed/NCBI
|
6
|
Ray EM and Sanoff HK: Optimal therapy for
patients with hepatocellular carcinoma and resistance or
intolerance to sorafenib: Challenges and solutions. J Hepatocell
Carcinoma. 4:131–138. 2017. View Article : Google Scholar : PubMed/NCBI
|
7
|
Saccoccia F, Angelucci F, Boumis G,
Carotti D, Desiato G, Miele AE and Bellelli A: Thioredoxin
reductase and its inhibitors. Curr Protein Pept Sci. 15:621–646.
2014. View Article : Google Scholar : PubMed/NCBI
|
8
|
Zhang J, Li X, Han X, Liu R and Fang J:
Targeting the thioredoxin system for cancer therapy. Trends
Pharmacol Sci. 38:794–808. 2017. View Article : Google Scholar : PubMed/NCBI
|
9
|
Cheng X, Holenya P, Can S, Alborzinia H,
Rubbiani R, Ott I and Wölfl S: A TrxR inhibiting gold(I) NHC
complex induces apoptosis through ASK1-p38-MAPK signaling in
pancreatic cancer cells. Mol Cancer. 13:2212014. View Article : Google Scholar : PubMed/NCBI
|
10
|
Hellfritsch J, Kirsch J, Schneider M,
Fluege T, Wortmann M, Frijhoff J, Dagnell M, Fey T, Esposito I,
Kölle P, et al: Knockout of mitochondrial thioredoxin reductase
stabilizes prolyl hydroxylase 2 and inhibits tumor growth and
tumor-derived angiogenesis. Antioxid Redox Signal. 22:938–950.
2015. View Article : Google Scholar : PubMed/NCBI
|
11
|
Harris IS, Treloar AE, Inoue S, Sasaki M,
Gorrini C, Lee KC, Yung KY, Brenner D, Knobbe-Thomsen CB, Cox MA,
et al: Glutathione and thioredoxin antioxidant pathways synergize
to drive cancer initiation and progression. Cancer Cell.
27:211–222. 2015. View Article : Google Scholar : PubMed/NCBI
|
12
|
Benhar M, Shytaj IL, Stamler JS and
Savarino A: Dual targeting of the thioredoxin and glutathione
systems in cancer and HIV. J Clin Invest. 126:1630–1639. 2016.
View Article : Google Scholar : PubMed/NCBI
|
13
|
Zhang D, Xu Z, Yuan J, Zhao YX, Qiao ZY,
Gao YJ, Yu GA, Li J and Wang H: Synthesis and molecular recognition
studies on small-molecule inhibitors for thioredoxin reductase. J
Med Chem. 57:8132–8139. 2014. View Article : Google Scholar : PubMed/NCBI
|
14
|
Rubbiani R, Kitanovic I, Alborzinia H, Can
S, Kitanovic A, Onambele LA, Stefanopoulou M, Geldmacher Y,
Sheldrick WS, Wolber G, et al: Benzimidazol-2-ylidene gold(I)
complexes are thioredoxin reductase inhibitors with multiple
antitumor properties. J Med Chem. 53:8608–8618. 2010. View Article : Google Scholar : PubMed/NCBI
|
15
|
Li C, Peng Y, Mao B and Qian K:
Thioredoxin reductase: A novel, independent prognostic marker in
patients with hepatocellular carcinoma. Oncotarget. 6:17792–17804.
2015.PubMed/NCBI
|
16
|
Zheng X, Ma W, Sun R, Yin H, Lin F, Liu Y,
Xu W and Zeng H: Butaselen prevents hepatocarcinogenesis and
progression through inhibiting thioredoxin reductase activity.
Redox Biol. 14:237–249. 2018. View Article : Google Scholar : PubMed/NCBI
|
17
|
López-Terrada D, Cheung SW, Finegold MJ
and Knowles BB: Hep G2 is a hepatoblastoma-derived cell line. Hum
Pathol. 40:1512–1515. 2009. View Article : Google Scholar
|
18
|
Sutton BM, McGusty E, Walz DT and
DiMartino MJ: Oral gold. Antiarthritic properties of
alkylphosphinegold coordination complexes. J Med Chem.
15:1095–1098. 1972. View Article : Google Scholar : PubMed/NCBI
|
19
|
Yang Y, Zheng B, Han Q, Zhang C, Tian Z
and Zhang J: Targeting blockage of STAT3 inhibits hepatitis B
virus-related hepatocellular carcinoma. Cancer Biol Ther.
17:449–456. 2016. View Article : Google Scholar : PubMed/NCBI
|
20
|
Chen W, Zou P, Zhao Z, Weng Q, Chen X,
Ying S, Ye Q, Wang Z, Ji J and Liang G: Selective killing of
gastric cancer cells by a small molecule via targeting TrxR1 and
ROS-mediated ER stress activation. Oncotarget. 7:16593–16609.
2016.PubMed/NCBI
|
21
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
22
|
Yang Y, Han Q, Hou Z, Zhang C, Tian Z and
Zhang J: Exosomes mediate hepatitis B virus (HBV) transmission and
NK-cell dysfunction. Cell Mol Immunol. 14:465–475. 2017. View Article : Google Scholar : PubMed/NCBI
|
23
|
Arambula JF, McCall R, Sidoran KJ, Magda
D, Mitchell NA, Bielawski CW, Lynch VM, Sessler JL and Arumugam K:
Targeting antioxidant pathways with ferrocenylated N-heterocyclic
carbene supported gold(I) complexes in A549 lung cancer cells. Chem
Sci. 7:1245–1256. 2016. View Article : Google Scholar : PubMed/NCBI
|
24
|
Gan P, Gao Z, Zhao X and Qi G: Surfactin
inducing mitochondria-dependent ROS to activate MAPKs, NF-κB and
inflammasomes in macrophages for adjuvant activity. Sci Rep.
6:393032016. View Article : Google Scholar : PubMed/NCBI
|
25
|
Kim J, Kundu M, Viollet B and Guan KL:
AMPK and mTOR regulate autophagy through direct phosphorylation of
Ulk1. Nat Cell Biol. 13:132–141. 2011. View
Article : Google Scholar : PubMed/NCBI
|
26
|
Din FV, Valanciute A, Houde VP, Zibrova D,
Green KA, Sakamoto K, Alessi DR and Dunlop MG: Aspirin inhibits
mTOR signaling, activates AMP-activated protein kinase, and induces
autophagy in colorectal cancer cells. Gastroenterology.
142(1504–1515): e3. 2012.PubMed/NCBI
|
27
|
Jin R, Gao Y, Zhang S, Teng F, Xu X, Aili
A, Wang Y, Sun X, Pang X, Ge Q and Zhang Y: Trx1/TrxR1 system
regulates post-selected DP thymocytes survival by modulating
ASK1-JNK/p38 MAPK activities. Immunol Cell Biol. 93:744–752. 2015.
View Article : Google Scholar : PubMed/NCBI
|
28
|
Zhang M, Harashima N, Moritani T, Huang W
and Harada M: The roles of ROS and caspases in TRAIL-induced
apoptosis and necroptosis in human pancreatic cancer cells. PLoS
One. 10:e01273862015. View Article : Google Scholar : PubMed/NCBI
|
29
|
Tsuchiya A, Kaku Y, Nakano T and Nishizaki
T: Diarachidonoylphosphoethanolamine induces apoptosis of malignant
pleural mesothelioma cells through a Trx/ASK1/p38 MAPK pathway. J
Pharmacol Sci. 129:160–168. 2015. View Article : Google Scholar : PubMed/NCBI
|
30
|
Zhang X, Qin J, Zou J, Lv Z, Tan B, Shi J,
Zhao Y, Ren H, Liu M, Qian M and Du B: Extracellular ADP
facilitates monocyte recruitment in bacterial infection via ERK
signaling. Cell Mol Immunol. 15:58–73. 2018. View Article : Google Scholar : PubMed/NCBI
|
31
|
Yokoi K, Kobayashi A, Motoyama H, Kitazawa
M, Shimizu A, Notake T, Yokoyama T, Matsumura T, Takeoka M and
Miyagawa SI: Survival pathway of cholangiocarcinoma via AKT/mTOR
signaling to escape RAF/MEK/ERK pathway inhibition by sorafenib.
Oncol Rep. 39:843–850. 2018.PubMed/NCBI
|
32
|
An H and Harper JW: Systematic analysis of
ribophagy in human cells reveals bystander flux during selective
autophagy. Nat Cell Biol. 20:135–143. 2018. View Article : Google Scholar : PubMed/NCBI
|
33
|
Nagakannan P and Eftekharpour E:
Differential redox sensitivity of cathepsin B and L holds the key
to autophagy-apoptosis interplay after Thioredoxin reductase
inhibition in nutritionally stressed SH-SY5Y cells. Free Radic Biol
Med. 108:819–831. 2017. View Article : Google Scholar : PubMed/NCBI
|
34
|
Lin YX, Gao YJ, Wang Y, Qiao ZY, Fan G,
Qiao SL, Zhang RX, Wang L and Wang H: pH-sensitive polymeric
nanoparticles with gold(I) compound payloads synergistically induce
cancer cell death through modulation of autophagy. Mol Pharm.
12:2869–2878. 2015. View Article : Google Scholar : PubMed/NCBI
|
35
|
Huang SY, Chien CC, Hseu RS, Huang VYJ,
Chiang SY, Huang CJ, Chen SK, Tsai RY, Lin HT and Cheng YC:
Ganoderma microsporum immunomodulatory protein induces apoptosis
and potentiates mitomycin C-induced apoptosis in urinary bladder
urothelial carcinoma cells. J Cell Biochem. 119:4592–4606. 2018.
View Article : Google Scholar : PubMed/NCBI
|
36
|
Wang X, Dong H, Li Q, Li Y and Hong A:
Thioredoxin induces Tregs to generate an immunotolerant tumor
microenvironment in metastatic melanoma. Oncoimmunology.
4:e10274712015. View Article : Google Scholar : PubMed/NCBI
|