1
|
Bray F, Ferlay J, Soerjomataram I, Siegel
RL, Torre LA and Jemal A: Global cancer statistics 2018: GLOBOCAN
estimates of incidence and mortality worldwide for 36 cancers in
185 countries. CA Cancer J Clin. 68:394–424. 2018. View Article : Google Scholar : PubMed/NCBI
|
2
|
Wang J, Wang T, Yang YY, Chai YL, Shi F
and Liu ZI: Patient age, tumor appearance and tumor size are risk
factors for early recurrence of cervical cancer. Mol Clin Oncol.
3:363–366. 2015. View Article : Google Scholar : PubMed/NCBI
|
3
|
Galluzzi L and Green DR:
Autophagy-independent functions of the autophagy machinery. Cell.
177:1682–1699. 2019. View Article : Google Scholar : PubMed/NCBI
|
4
|
White E: Deconvoluting the
context-dependent role for autophagy in cancer. Nat Rev Cancer.
12:401–410. 2012. View
Article : Google Scholar : PubMed/NCBI
|
5
|
Amaravadi R, Kimmelman AC and White E:
Recent insights into the function of autophagy in cancer. Genes
Dev. 30:1913–1930. 2016. View Article : Google Scholar : PubMed/NCBI
|
6
|
Guo W, Wang H, Yang Y, Guo S, Zhang W, Liu
Y, Yi X, Ma J, Zhao T, Liu L, et al: Down-regulated miR-23a
contributes to the metastasis of cutaneous melanoma by promoting
autophagy. Theranostics. 7:2231–2249. 2017. View Article : Google Scholar : PubMed/NCBI
|
7
|
Gao L, Lv G, Li R, Liu WT, Zong C, Ye F,
Li XY, Yang X, Jiang JH, Hou XJ, et al: Glycochenodeoxycholate
promotes hepatocellular carcinoma invasion and migration by
AMPK/mTOR dependent autophagy activation. Cancer Lett. 454:215–223.
2019. View Article : Google Scholar : PubMed/NCBI
|
8
|
Wang S, Zhu M, Wang Q, Hou Y, Li L, Weng
H, Zhao Y, Chen D, Ding H, Guo J and Li M: Alpha-fetoprotein
inhibits autophagy to promote malignant behaviour in hepatocellular
carcinoma cells by activating PI3K/AKT/mTOR signalling. Cell Death
Dis. 9:10272018. View Article : Google Scholar : PubMed/NCBI
|
9
|
Zhan J and Zhang H: Kindlins: Roles in
development and cancer progression. Int J Biochem Cell Biol.
98:93–103. 2018. View Article : Google Scholar : PubMed/NCBI
|
10
|
Ou YW, Zhao ZT, Wu CY, Xu BN, Song YM and
Zhan QM: Mig-2 attenuates cisplatin-induced apoptosis of human
glioma cells in vitro through AKT/JNK and AKT/p38 signaling
pathways. Acta Pharmacol Sin. 35:1199–1206. 2014. View Article : Google Scholar : PubMed/NCBI
|
11
|
Sossey-Alaoui K, Pluskota E, Bialkowska K,
Szpak D, Parker Y, Morrison CD, Lindner DJ, Schiemann WP and Plow
EF: Kindlin-2 regulates the growth of breast cancer tumors by
activating CSF-1-mediated macrophage infiltration. Cancer Res.
77:5129–5141. 2017. View Article : Google Scholar : PubMed/NCBI
|
12
|
Yoshida N, Masamune A, Hamada S, Kikuta K,
Takikawa T, Motoi F, Unno M and Shimosegawa T: Kindlin-2 in
pancreatic stellate cells promotes the progression of pancreatic
cancer. Cancer Lett. 390:103–114. 2017. View Article : Google Scholar : PubMed/NCBI
|
13
|
Heras-Sandoval D, Pérez-Rojas JM,
Hernández-Damián J and Pedraza-Chaverri J: The role of
PI3K/AKT/mTOR pathway in the modulation of autophagy and the
clearance of protein aggregates in neurodegeneration. Cell Signal.
26:2694–2701. 2014. View Article : Google Scholar : PubMed/NCBI
|
14
|
Rabanal-Ruiz Y, Otten EG and Korolchuk VI:
mTORC1 as the main gateway to autophagy. Essays Biochem.
61:565–584. 2017. View Article : Google Scholar : PubMed/NCBI
|
15
|
Aran D, Camarda R, Odegaard J, Paik H,
Oskotsky B, Krings G, Goga A, Sirota M and Butte AJ: Comprehensive
analysis of normal adjacent to tumor transcriptomes. Nat Commun.
8:10772017. View Article : Google Scholar : PubMed/NCBI
|
16
|
Lee YY, Kim TJ, Kim JY, Choi CH, Do IG,
Song SY, Sohn I, Jung SH, Bae DS, Lee JW and Kim BG: Genetic
profiling to predict recurrence of early cervical cancer. Gynecol
Oncol. 131:650–654. 2013. View Article : Google Scholar : PubMed/NCBI
|
17
|
Medina-Martinez I, Barrón V,
Roman-Bassaure E, Juárez-Torres E, Guardado-Estrada M, Espinosa AM,
Bermudez M, Fernández F, Venegas-Vega C, Orozco L, et al: Impact of
gene dosage on gene expression, biological processes and survival
in cervical cancer: A genome-wide follow-up study. PLoS One.
9:e978422014. View Article : Google Scholar : PubMed/NCBI
|
18
|
Tang Z, Li C, Kang B, Gao G, Li C and
Zhang Z: GEPIA: A web server for cancer and normal gene expression
profiling and interactive analyses. Nucleic Acids Res. 45:W98–W102.
2017. View Article : Google Scholar : PubMed/NCBI
|
19
|
Ogłuszka M, Orzechowska M, Jędroszka D,
Witas P and Bednarek AK: Evaluate Cutpoints: Adaptable continuous
data distribution system for determining survival in kaplan-meier
estimator. Comput Methods Programs Biomed. 177:133–139. 2019.
View Article : Google Scholar : PubMed/NCBI
|
20
|
Tanida I, Ueno T and Kominami E: LC3 and
autophagy. Methods Mol Biol. 445:77–88. 2008. View Article : Google Scholar : PubMed/NCBI
|
21
|
Moscat J and Diaz-Meco MT: p62 at the
crossroads of autophagy, apoptosis, and cancer. Cell.
137:1001–1004. 2009. View Article : Google Scholar : PubMed/NCBI
|
22
|
Mizushima N, Yoshimori T and Levine B:
Methods in mammalian autophagy research. Cell. 140:313–326. 2010.
View Article : Google Scholar : PubMed/NCBI
|
23
|
Janku F, McConkey DJ, Hong DS and Kurzrock
R: Autophagy as a target for anticancer therapy. Nat Rev Clin
Oncol. 8:528–539. 2011. View Article : Google Scholar : PubMed/NCBI
|
24
|
Saiki S, Sasazawa Y, Imamichi Y, Kawajiri
S, Fujimaki T, Tanida I, Kobayashi H, Sato F, Sato S, Ishikawa K,
et al: Caffeine induces apoptosis by enhancement of autophagy via
PI3K/Akt/mTOR/p70S6K inhibition. Autophagy. 7:176–187. 2011.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Guo B, Gao J, Zhan J and Zhang H:
Kindlin-2 interacts with and stabilizes EGFR and is required for
EGF-induced breast cancer cell migration. Cancer Lett. 361:271–281.
2015. View Article : Google Scholar : PubMed/NCBI
|
26
|
Shen Z, Ye Y, Kauttu T, Seppänen H,
Vainionpää S, Wang S, Mustonen H and Puolakkainen P: Novel focal
adhesion protein kindlin-2 promotes the invasion of gastric cancer
cells through phosphorylation of integrin β1 and β3. J Surg Oncol.
108:106–112. 2013. View Article : Google Scholar : PubMed/NCBI
|
27
|
An Z, Dobra K, Lock JG, Strömblad S,
Hjerpe A and Zhang H: Kindlin-2 is expressed in malignant
mesothelioma and is required for tumor cell adhesion and migration.
Int J Cancer. 127:1999–2008. 2010. View Article : Google Scholar : PubMed/NCBI
|
28
|
Ren C, Du J, Xi C, Yu Y, Hu A, Zhan J, Guo
H, Fang W, Liu C and Zhang H: Kindlin-2 inhibits serous epithelial
ovarian cancer peritoneal dissemination and predicts patient
outcomes. Biochem Biophys Res Commun. 446:187–194. 2014. View Article : Google Scholar : PubMed/NCBI
|
29
|
Shi X and Wu C: A suppressive role of
mitogen inducible gene-2 in mesenchymal cancer cell invasion. Mol
Cancer Res. 6:715–724. 2008. View Article : Google Scholar : PubMed/NCBI
|
30
|
White E, Mehnert JM and Chan CS:
Autophagy, metabolism, and cancer. Clin Cancer Res. 21:5037–5046.
2015. View Article : Google Scholar : PubMed/NCBI
|
31
|
White E: The role for autophagy in cancer.
J Clin Invest. 125:42–46. 2015. View
Article : Google Scholar : PubMed/NCBI
|
32
|
Hsin MC, Hsieh YH, Wang PH, Ko JL, Hsin IL
and Yang SF: Hispolon suppresses metastasis via autophagic
degradation of cathepsin S in cervical cancer cells. Cell Death
Dis. 8:e30892017. View Article : Google Scholar : PubMed/NCBI
|
33
|
Chen Y, Zhuang H, Chen X, Shi Z and Wang
X: Spermidine-induced growth inhibition and apoptosis via
autophagic activation in cervical cancer. Oncol Rep. 39:2845–2854.
2018.PubMed/NCBI
|
34
|
Kenific CM, Thorburn A and Debnath J:
Autophagy and metastasis: Another double-edged sword. Curr Opin
Cell Biol. 22:241–245. 2010. View Article : Google Scholar : PubMed/NCBI
|
35
|
Dower CM, Wills CA, Frisch SM and Wang HG:
Mechanisms and context underlying the role of autophagy in cancer
metastasis. Autophagy. 14:1110–1128. 2018. View Article : Google Scholar : PubMed/NCBI
|
36
|
Zhang M, Liu S, Chua MS, Li H, Luo D, Wang
S, Zhang S, Han B and Sun C: SOCS5 inhibition induces autophagy to
impair metastasis in hepatocellular carcinoma cells via the
PI3K/Akt/mTOR pathway. Cell Death Dis. 10:6122019. View Article : Google Scholar : PubMed/NCBI
|
37
|
Zhang Y, Fan Y, Huang S, Wang G, Han R,
Lei F, Luo A, Jing X, Zhao L, Gu S and Zhao X: Thymoquinone
inhibits the metastasis of renal cell cancer cells by inducing
autophagy via AMPK/mTOR signaling pathway. Cancer Sci.
109:3865–3873. 2018. View Article : Google Scholar : PubMed/NCBI
|
38
|
Chu CA, Lee CT, Lee JC, Wang YW, Huang CT,
Lan SH, Lin PC, Lin BW, Tian YF, Liu HS and Chow NH: MiR-338-5p
promotes metastasis of colorectal cancer by inhibition of
phosphatidylinositol 3-kinase, catalytic subunit type 3-mediated
autophagy pathway. EBioMedicine. 43:270–281. 2019. View Article : Google Scholar : PubMed/NCBI
|
39
|
Porta C, Paglino C and Mosca A: Targeting
PI3K/Akt/mTOR signaling in cancer. Front Oncol. 4:642014.
View Article : Google Scholar : PubMed/NCBI
|
40
|
Mabuchi S, Kuroda H, Takahashi R and
Sasano T: The PI3K/AKT/mTOR pathway as a therapeutic target in
ovarian cancer. Gynecol Oncol. 137:173–179. 2015. View Article : Google Scholar : PubMed/NCBI
|
41
|
Slomovitz BM and Coleman RL: The
PI3K/AKT/mTOR pathway as a therapeutic target in endometrial
cancer. Clin Cancer Res. 18:5856–5864. 2012. View Article : Google Scholar : PubMed/NCBI
|
42
|
Lee JJ, Loh K and Yap YS: PI3K/Akt/mTOR
inhibitors in breast cancer. Cancer Biol Med. 12:342–354.
2015.PubMed/NCBI
|