1
|
Döhner H, Weisdorf DJ and Bloomfield CD:
Acute myeloid leukemia. N Engl J Med. 373:1136–1152. 2015.
View Article : Google Scholar : PubMed/NCBI
|
2
|
Thomas D and Majeti R: Biology and
relevance of human acute myeloid leukemia stem cells. Blood.
129:1577–1585. 2017. View Article : Google Scholar : PubMed/NCBI
|
3
|
Ho TC, LaMere M, Stevens BM, Ashton JM,
Myers JR, O'Dwyer KM, Liesveld JL, Mendler JH, Guzman M,
Morrissette JD, et al: Evolution of acute myelogenous leukemia stem
cell properties after treatment and progression. Blood.
128:1671–1678. 2016. View Article : Google Scholar : PubMed/NCBI
|
4
|
Rothe K, Porter V and Jiang X: Current
outlook on autophagy in human leukemia: Foe in cancer stem cells
and drug resistance, friend in new therapeutic interventions. Int J
Mol Sci. 20:4612019. View Article : Google Scholar
|
5
|
Hansen M, Rubinsztein DC and Walker DW:
Autophagy as a promoter of longevity: Insights from model
organisms. Nat Rev Mol Cell Biol. 19:579–593. 2018. View Article : Google Scholar : PubMed/NCBI
|
6
|
Larrue C, Saland E, Boutzen H, Vergez F,
David M, Joffre C, Hospital MA, Tamburini J, Delabesse E, Manenti
S, et al: Proteasome inhibitors induce FLT3-ITD degradation through
autophagy in AML cells. Blood. 127:882–892. 2016. View Article : Google Scholar : PubMed/NCBI
|
7
|
Jin J, Britschgi A, Schläfli AM, Humbert
M, Shan-Krauer D, Batliner J, Federzoni EA, Ernst M, Torbett BE,
Yousefi S, et al: Low autophagy (ATG) gene expression is associated
with an immature AML blast cell phenotype and can be restored
during AML differentiation therapy. Oxid Med Cell Longev.
2018:14827952018. View Article : Google Scholar : PubMed/NCBI
|
8
|
Mohamadimaram M, Allahbakhshian Farsani M,
Mirzaeian A, Shahsavan S, Hajifathali A, Parkhihdeh S and Mohammadi
MH: Evaluation of ATG7 and light chain 3 (LC3) autophagy genes
expression in AML patients. Iran J Pharm Res. 18:1060–1066.
2019.PubMed/NCBI
|
9
|
Rudat S, Pfaus A, Cheng YY, Holtmann J,
Ellegast JM, Bühler C, Marcantonio DD, Martinez E, Göllner S,
Wickenhauser C, et al: RET-mediated autophagy suppression as
targetable co-dependence in acute myeloid leukemia. Leukemia.
32:2189–2202. 2018. View Article : Google Scholar : PubMed/NCBI
|
10
|
Hu X, Mei S, Meng W, Xue S, Jiang L, Yang
Y, Hui L, Chen Y and Guan MX: CXCR4-mediated signaling regulates
autophagy and influences acute myeloid leukemia cell survival and
drug resistance. Cancer Lett. 425:1–12. 2018. View Article : Google Scholar : PubMed/NCBI
|
11
|
Heydt Q, Larrue C, Saland E, Bertoli S,
Sarry JE, Besson A, Manenti S, Joffre C and Mansat-De Mas V:
Oncogenic FLT3-ITD supports autophagy via ATF4 in acute myeloid
leukemia. Oncogene. 37:787–797. 2018. View Article : Google Scholar : PubMed/NCBI
|
12
|
Siriboonpiputtana T, Zeisig BB, Zarowiecki
M, Fung TK, Mallardo M, Tsai CT, Lau PNI, Hoang QC, Veiga P, Barnes
J, et al: Transcriptional memory of cells of origin overrides
β-catenin requirement of MLL cancer stem cells. EMBO J.
36:3139–3155. 2017. View Article : Google Scholar : PubMed/NCBI
|
13
|
Zhang Y, Xia F, Liu X, Yu Z, Xie L, Liu L,
Chen C, Jiang H, Hao X, He X, et al: JAM3 maintains
leukemia-initiating cell self-renewal through
LRP5/AKT/β-catenin/CCND1 signaling. J Clin Invest. 128:1737–1751.
2018. View
Article : Google Scholar : PubMed/NCBI
|
14
|
Thorne CA, Hanson AJ, Schneider J, Tahinci
E, Orton D, Cselenyi CS, Jernigan KK, Meyers KC, Hang BI, Waterson
AG, et al: Small-molecule inhibition of Wnt signaling through
activation of casein kinase 1α. Nat Chem Biol. 6:829–836. 2010.
View Article : Google Scholar : PubMed/NCBI
|
15
|
Chang CH, Kuo CJ, Ito T, Su YY, Jiang ST,
Chiu MH, Lin YH, Nist A, Mernberger M, Stiewe T, et al: CK1α
ablation in keratinocytes induces p53-dependent, sunburn-protective
skin hyperpigmentation. Proc Natl Acad Sci USA. 114:E8035–E8044.
2017. View Article : Google Scholar : PubMed/NCBI
|
16
|
Elyada E, Pribluda A, Goldstein RE,
Morgenstern Y, Brachya G, Cojocaru G, Snir-Alkalay I, Burstain I,
Haffner-Krausz R, Jung S, et al: CKIα ablation highlights a
critical role for p53 in invasiveness control. Nature. 470:409–413.
2011. View Article : Google Scholar : PubMed/NCBI
|
17
|
Rodriguez-Blanco J, Li B, Long J, Shen C,
Yang F, Orton D, Collins S, Kasahara N, Ayad NG, McCrea HJ, et al:
A CK1α activator penetrates the brain and shows efficacy against
drug-resistant metastatic medulloblastoma. Clin Cancer Res.
25:1379–1388. 2019. View Article : Google Scholar : PubMed/NCBI
|
18
|
Minzel W, Venkatachalam A, Fink A, Hung E,
Brachya G, Burstain I, Shaham M, Rivlin A, Omer I, Zinger A, et al:
Small molecules co-targeting CKIα and the transcriptional kinases
CDK7/9 control AML in preclinical models. Cell. 175:171–185.e125.
2018. View Article : Google Scholar : PubMed/NCBI
|
19
|
Cheong JK, Zhang F, Chua PJ, Bay BH,
Thorburn A and Virshup DM: Casein kinase 1α-dependent feedback loop
controls autophagy in RAS-driven cancers. J Clin Invest.
125:1401–1418. 2015. View
Article : Google Scholar : PubMed/NCBI
|
20
|
Liu J, Xia H, Kim M, Xu L, Li Y, Zhang L,
Cai Y, Norberg HV, Zhang T, Furuya T, et al: Beclin1 controls the
levels of p53 by regulating the deubiquitination activity of USP10
and USP13. Cell. 147:223–234. 2011. View Article : Google Scholar : PubMed/NCBI
|
21
|
Rena G, Bain J, Elliott M and Cohen P:
D4476, a cell-permeant inhibitor of CK1, suppresses the
site-specific phosphorylation and nuclear exclusion of FOXO1a. EMBO
Rep. 5:60–65. 2004. View Article : Google Scholar : PubMed/NCBI
|
22
|
Chandrashekar DS, Bashel B, Balasubramanya
SAH, Creighton CJ, Ponce-Rodriguez I, Chakravarthi BVSK and
Varambally S: UALCAN: A portal for facilitating tumor subgroup gene
expression and survival analyses. Neoplasia. 19:649–658. 2017.
View Article : Google Scholar : PubMed/NCBI
|
23
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
24
|
Qian S, Han Y, Shi Y, Xu W, Zhu Y, Jiang
S, Chen Y, Yu Z, Zhang S, Yang Y, et al: Benzene induces
haematotoxicity by promoting deacetylation and autophagy. J Cell
Mol Med. 23:1022–1033. 2019. View Article : Google Scholar : PubMed/NCBI
|
25
|
Li XX, Guo H, Zhou JD, Wu DH, Ma JC, Wen
XM, Zhang W, Xu ZJ, Lin J and Jun Q: Overexpression of CTNNB1:
Clinical implication in Chinese de novo acute myeloid leukemia.
Pathol Res Pract. 214:361–367. 2018. View Article : Google Scholar : PubMed/NCBI
|
26
|
Petherick KJ, Williams AC, Lane JD,
Ordóñez-Morán P, Huelsken J, Collard TJ, Smartt HJ, Batson J, Malik
K, Paraskeva C and Greenhough A: Autolysosomal β-catenin
degradation regulates Wnt-autophagy-p62 crosstalk. EMBO J.
32:1903–1916. 2013. View Article : Google Scholar : PubMed/NCBI
|
27
|
Hardie DG, Scott JW, Pan DA and Hudson ER:
Management of cellular energy by the AMP-activated protein kinase
system. FEBS Lett. 546:113–120. 2003. View Article : Google Scholar : PubMed/NCBI
|
28
|
Wang F, Song W, Zhao H, Ma Y, Li Y, Zhai
D, Pi J, Si Y, Xu J, Dong L, et al: The RNA-binding protein QKI5
regulates primary miR-124-1 processing via a distal RNA motif
during erythropoiesis. Cell Res. 27:416–439. 2017. View Article : Google Scholar : PubMed/NCBI
|
29
|
Huang X, Wu Z, Mei Y and Wu M: XIAP
inhibits autophagy via XIAP-Mdm2-p53 signalling. EMBO J.
32:2204–2216. 2013. View Article : Google Scholar : PubMed/NCBI
|
30
|
Chae YB and Kim MM: Activation of p53 by
spermine mediates induction of autophagy in HT1080 cells. Int J
Biol Macromol. 63:56–63. 2014. View Article : Google Scholar : PubMed/NCBI
|
31
|
Sui X, Jin L, Huang X, Geng S, He C and Hu
X: p53 signaling and autophagy in cancer: A revolutionary strategy
could be developed for cancer treatment. Autophagy. 7:565–571.
2011. View Article : Google Scholar : PubMed/NCBI
|
32
|
Järås M, Miller PG, Chu LP, Puram RV, Fink
EC, Schneider RK, Al-Shahrour F, Peña P, Breyfogle LJ, Hartwell KA,
et al: Csnk1a1 inhibition has p53-dependent therapeutic efficacy in
acute myeloid leukemia. J Exp Med. 211:605–612. 2014. View Article : Google Scholar : PubMed/NCBI
|
33
|
Chen L, Li C, Pan Y and Chen J: Regulation
of p53-MDMX interaction by casein kinase 1 alpha. Mol Cell Biol.
25:6509–6520. 2005. View Article : Google Scholar : PubMed/NCBI
|
34
|
Schittek B and Sinnberg T: Biological
functions of casein kinase 1 isoforms and putative roles in
tumorigenesis. Mol Cancer. 13:2312014. View Article : Google Scholar : PubMed/NCBI
|
35
|
Richter J, Kretz AL, Lemke J, Fauler M,
Werner JU, Paschke S, Leithäuser F, Henne-Bruns D, Hillenbrand A
and Knippschild U: CK1α overexpression correlates with poor
survival in colorectal cancer. BMC Cancer. 18:1402018. View Article : Google Scholar : PubMed/NCBI
|
36
|
Carrino M, Quotti Tubi L, Fregnani A,
Canovas Nunes S, Barilà G, Trentin L, Zambello R, Semenzato G,
Manni S and Piazza F: Prosurvival autophagy is regulated by protein
kinase CK1 alpha in multiple myeloma. Cell Death Discov. 5:982019.
View Article : Google Scholar : PubMed/NCBI
|
37
|
Duran A, Amanchy R, Linares JF, Joshi J,
Abu-Baker S, Porollo A, Hansen M, Moscat J and Diaz-Meco MT: p62 is
a key regulator of nutrient sensing in the mTORC1 pathway. Mol
Cell. 44:134–146. 2011. View Article : Google Scholar : PubMed/NCBI
|
38
|
Ma R, Zhang Y, Wang W, Wu J, Yang Q, Xu W,
Jiang S, Han Y, Yu K and Zhang S: Inhibition of autophagy enhances
the antitumour activity of tigecycline in multiple myeloma. J Cell
Mol Med. 22:5955–5963. 2018. View Article : Google Scholar : PubMed/NCBI
|
39
|
Kojima K, Konopleva M, Samudio IJ, Schober
WD, Bornmann WG and Andreeff M: Concomitant inhibition of MDM2 and
Bcl-2 protein function synergistically induce mitochondrial
apoptosis in AML. Cell Cycle. 5:2778–2786. 2006. View Article : Google Scholar : PubMed/NCBI
|
40
|
Huart AS, MacLaine NJ, Meek DW and Hupp
TR: CK1alpha plays a central role in mediating MDM2 control of p53
and E2F-1 protein stability. J Biol Chem. 284:32384–32394. 2009.
View Article : Google Scholar : PubMed/NCBI
|
41
|
Perry ME, Piette J, Zawadzki JA, Harvey D
and Levine AJ: The mdm-2 gene is induced in response to UV light in
a p53-dependent manner. Proc Natl Acad Sci USA. 90:11623–11627.
1993. View Article : Google Scholar : PubMed/NCBI
|