Open Access

Role of MRI‑based radiomics in locally advanced rectal cancer (Review)

  • Authors:
    • Siyu Zhang
    • Mingrong Yu
    • Dan Chen
    • Peidong Li
    • Bin Tang
    • Jie Li
  • View Affiliations

  • Published online on: December 21, 2021     https://doi.org/10.3892/or.2021.8245
  • Article Number: 34
  • Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Colorectal cancer is the third most common type of cancer, with high morbidity and mortality rates. In particular, locally advanced rectal cancer (LARC) is difficult to treat and has a high recurrence rate. Neoadjuvant chemoradiotherapy (NCRT) is one of the standard treatment programs of LARC. If the response to treatment and prognosis in patients with LARC can be predicted, it will guide clinical decision‑making. Radiomics is characterized by the extraction of high‑dimensional quantitative features from medical imaging data, followed by data analysis and model construction, which can be used for tumor diagnosis, staging, prediction of treatment response and prognosis. In recent years, a number of studies have assessed the role of radiomics in NCRT for LARC. MRI‑based radiomics provides valuable data and is expected to become an imaging biomarker for predicting treatment response and prognosis. The potential of radiomics to guide personalized medicine is widely recognized; however, current limitations and challenges prevent its application to clinical decision‑making. The present review summarizes the applications, limitations and prospects of MRI‑based radiomics in LARC.
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February-2022
Volume 47 Issue 2

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Copy and paste a formatted citation
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Spandidos Publications style
Zhang S, Yu M, Chen D, Li P, Tang B and Li J: Role of MRI‑based radiomics in locally advanced rectal cancer (Review). Oncol Rep 47: 34, 2022.
APA
Zhang, S., Yu, M., Chen, D., Li, P., Tang, B., & Li, J. (2022). Role of MRI‑based radiomics in locally advanced rectal cancer (Review). Oncology Reports, 47, 34. https://doi.org/10.3892/or.2021.8245
MLA
Zhang, S., Yu, M., Chen, D., Li, P., Tang, B., Li, J."Role of MRI‑based radiomics in locally advanced rectal cancer (Review)". Oncology Reports 47.2 (2022): 34.
Chicago
Zhang, S., Yu, M., Chen, D., Li, P., Tang, B., Li, J."Role of MRI‑based radiomics in locally advanced rectal cancer (Review)". Oncology Reports 47, no. 2 (2022): 34. https://doi.org/10.3892/or.2021.8245