1
|
Zong WX, Rabinowitz JD and White E:
Mitochondria and cancer. Mol Cell. 61:667–676. 2016. View Article : Google Scholar : PubMed/NCBI
|
2
|
Rangaraju V, Lewis TJ Jr, Hirabayashi Y,
Bergami M, Motori E, Cartoni R, Kwon SK and Courchet J: Pleiotropic
mitochondria: The influence of mitochondria on neuronal development
and disease. J Neurosci. 39:8200–8208. 2019. View Article : Google Scholar : PubMed/NCBI
|
3
|
Tilokani L, Nagashima S, Paupe V and
Prudent J: Mitochondrial dynamics: Overview of molecular
mechanisms. Essays Biochem. 62:341–360. 2018. View Article : Google Scholar : PubMed/NCBI
|
4
|
Schmitt K, Grimm A, Dallmann R,
Oettinghaus B, Restelli LM, Witzig M, Ishihara N, Mihara K,
Ripperger JA, Albrecht U, et al: Circadian control of DRP1 activity
regulates mitochondrial dynamics and bioenergetics. Cell Metab.
27:657–666.e5. 2018. View Article : Google Scholar : PubMed/NCBI
|
5
|
Zhou BH, Wei SS, Jia LS, Zhang Y, Miao CY
and Wang HW: Drp1/Mff signaling pathway is involved in
fluoride-induced abnormal fission of hepatocyte mitochondria in
mice. Sci Total Environ. 725:1381922020. View Article : Google Scholar : PubMed/NCBI
|
6
|
Ma Y, Wang L and Jia R: The role of
mitochondrial dynamics in human cancers. Am J Cancer Res.
10:1278–1293. 2020.PubMed/NCBI
|
7
|
Chauhan SS, Toth RK, Jensen CC, Casillas
AL, Kashatus DF and Warfel NA: PIM kinases alter mitochondrial
dynamics and chemosensitivity in lung cancer. Oncogene.
39:2597–2611. 2020. View Article : Google Scholar : PubMed/NCBI
|
8
|
Zhou D, Ren K, Wang M, Wang J, Li E, Hou
C, Su Y, Jin Y, Zou Q, Zhou P and Liu X: Long non-coding RNA
RACGAP1P promotes breast cancer invasion and metastasis via
miR-345-5p/RACGAP1-mediated mitochondrial fission. Mol Oncol.
15:543–559. 2021. View Article : Google Scholar : PubMed/NCBI
|
9
|
Kamradt ML, Jung JU, Pflug KM, Lee DW,
Fanniel V and Sitcheran R: NIK promotes metabolic adaptation of
glioblastoma cells to bioenergetic stress. Cell Death Dis.
12:2712021. View Article : Google Scholar : PubMed/NCBI
|
10
|
Zhang BY, Zhang L, Chen YM, Qiao X, Zhao
SL, Li P, Liu JF, Wen X and Yang J: Corosolic acid inhibits
colorectal cancer cells growth as a novel HER2/HER3
heterodimerization inhibitor. Br J Pharmacol. 178:1475–1491. 2021.
View Article : Google Scholar : PubMed/NCBI
|
11
|
Courtois S, de Luxán-Delgado B,
Penin-Peyta L, Royo-García A, Parejo-Alonso B, Jagust P, Alcalá S,
Rubiolo JA, Sánchez L, Sainz B Jr, et al: Inhibition of
mitochondrial dynamics preferentially targets pancreatic cancer
cells with enhanced tumorigenic and invasive potential. Cancers
(Basel). 13:6982021. View Article : Google Scholar : PubMed/NCBI
|
12
|
Zhou TJ, Zhang SL, He CY, Zhuang QY, Han
PY, Jiang SW, Yao H, Huang YJ, Ling WH, Lin YC and Lin ZN:
Downregulation of mitochondrial cyclooxygenase-2 inhibits the
stemness of nasopharyngeal carcinoma by decreasing the activity of
dynamin-related protein 1. Theranostics. 7:1389–1406. 2017.
View Article : Google Scholar : PubMed/NCBI
|
13
|
Ferraz LS, Costa RTD, Costa CAD, Ribeiro
CAJ, Arruda DC, Maria-Engler SS and Rodrigues T: Targeting
mitochondria in melanoma: Interplay between MAPK signaling pathway
and mitochondrial dynamics. Biochem Pharmacol. 178:1141042020.
View Article : Google Scholar : PubMed/NCBI
|
14
|
Qian W, Wang J and Van Houten B: The role
of dynamin-related protein 1 in cancer growth: A promising
therapeutic target? Expert Opin Ther Targets. 17:997–1001. 2013.
View Article : Google Scholar : PubMed/NCBI
|
15
|
Luza S, Opazo CM, Bousman CA, Pantelis C,
Bush AI and Everall IP: The ubiquitin proteasome system and
schizophrenia. Lancet Psychiatry. 7:528–537. 2020. View Article : Google Scholar : PubMed/NCBI
|
16
|
Zhu D, Xu R, Huang X, Tang Z, Tian Y,
Zhang J and Zheng X: Deubiquitinating enzyme OTUB1 promotes cancer
cell immunosuppression via preventing ER-associated degradation of
immune checkpoint protein PD-L1. Cell Death Differ. 28:1773–1789.
2021. View Article : Google Scholar : PubMed/NCBI
|
17
|
Park HB, Kim JW and Baek KH: Regulation of
Wnt signaling through ubiquitination and deubiquitination in
cancers. Int J Mol Sci. 21:39042020. View Article : Google Scholar : PubMed/NCBI
|
18
|
Sun T, Liu Z and Yang Q: The role of
ubiquitination and deubiquitination in cancer metabolism. Mol
Cancer. 19:1462020. View Article : Google Scholar : PubMed/NCBI
|
19
|
Sukenik S, Braunstein I and Stanhill A: An
arsenite relay between PSMD14 and AIRAP enables revival of
proteasomal DUB activity. Biomolecules. 11:13172021. View Article : Google Scholar : PubMed/NCBI
|
20
|
Lv J, Zhang S, Wu H, Lu J, Lu Y, Wang F,
Zhao W, Zhan P, Lu J, Fang Q, et al: Deubiquitinase PSMD14 enhances
hepatocellular carcinoma growth and metastasis by stabilizing GRB2.
Cancer Lett. 469:22–34. 2020. View Article : Google Scholar : PubMed/NCBI
|
21
|
Luo G, Hu N, Xia X, Zhou J and Ye C: RPN11
deubiquitinase promotes proliferation and migration of breast
cancer cells. Mol Med Rep. 16:331–338. 2017. View Article : Google Scholar : PubMed/NCBI
|
22
|
Yu W, Li J, Wang Q, Wang B, Zhang L, Liu
Y, Tang M, Xu G, Yang Z, Wang X, et al: Targeting POH1 inhibits
prostate cancer cell growth and enhances the suppressive efficacy
of androgen deprivation and docetaxel. Prostate. 79:1304–1315.
2019. View Article : Google Scholar : PubMed/NCBI
|
23
|
Zhang L, Xu H, Ma C, Zhang J, Zhao Y, Yang
X, Wang S and Li D: Upregulation of deubiquitinase PSMD14 in lung
adenocarcinoma (LUAD) and its prognostic significance. J Cancer.
11:2962–2971. 2020. View Article : Google Scholar : PubMed/NCBI
|
24
|
Byrne A, McLaren RP, Mason P, Chai L,
Dufault MR, Huang Y, Liang B, Gans JD, Zhang M, Carter K, et al:
Knockdown of human deubiquitinase PSMD14 induces cell cycle arrest
and senescence. Exp Cell Res. 316:258–271. 2010. View Article : Google Scholar : PubMed/NCBI
|
25
|
Jing C, Duan Y, Zhou M, Yue K, Zhuo S, Li
X, Liu D, Ye B, Lai Q, Li L, et al: Blockade of deubiquitinating
enzyme PSMD14 overcomes chemoresistance in head and neck squamous
cell carcinoma by antagonizing E2F1/Akt/SOX2-mediated stemness.
Theranostics. 11:2655–2669. 2021. View Article : Google Scholar : PubMed/NCBI
|
26
|
Zhi T, Jiang K, Xu X, Yu T, Zhou F, Wang
Y, Liu N and Zhang J: ECT2/PSMD14/PTTG1 axis promotes the
proliferation of glioma through stabilizing E2F1. Neuro Oncol.
21:462–473. 2019. View Article : Google Scholar : PubMed/NCBI
|
27
|
Jing C, Li X, Zhou M, Zhang S, Lai Q, Liu
D, Ye B, Li L, Wu Y, Li H, et al: The PSMD14 inhibitor Thiolutin as
a novel therapeutic approach for esophageal squamous cell carcinoma
through facilitating SNAIL degradation. Theranostics. 11:5847–5862.
2021. View Article : Google Scholar : PubMed/NCBI
|
28
|
Rao X, Huang X, Zhou Z and Lin X: An
improvement of the 2ˆ(−delta delta CT) method for quantitative
real-time polymerase chain reaction data analysis. Biostat
Bioinforma Biomath. 3:71–85. 2013.PubMed/NCBI
|
29
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
30
|
Asmamaw MD, Liu Y, Zheng YC, Shi XJ and
Liu HM: Skp2 in the ubiquitin-proteasome system: A comprehensive
review. Med Res Rev. 40:1920–1949. 2020. View Article : Google Scholar : PubMed/NCBI
|
31
|
Wang J and Maldonado MA: The
ubiquitin-proteasome system and its role in inflammatory and
autoimmune diseases. Cell Mol Immunol. 3:255–261. 2006.PubMed/NCBI
|
32
|
Singh SR, Meyer-Jens M, Alizoti E, Bacon
WC, Davis G, Osinska H, Gulick J, Reischmann-Düsener S, Orthey E,
McLendon PM, et al: A high-throughput screening identifies ZNF418
as a novel regulator of the ubiquitin-proteasome system and
autophagy-lysosomal pathway. Autophagy. 17:3124–3139. 2021.
View Article : Google Scholar : PubMed/NCBI
|
33
|
Narayanan S, Cai CY, Assaraf YG, Guo HQ,
Cui Q, Wei L, Huang JJ, Ashby CR Jr and Chen ZS: Targeting the
ubiquitin-proteasome pathway to overcome anti-cancer drug
resistance. Drug Resist Updat. 48:1006632020. View Article : Google Scholar : PubMed/NCBI
|
34
|
Yerlikaya A, Kanbur E, Stanley BA and
Tümer E: The ubiquitin-proteasome pathway and epigenetic
modifications in cancer. Anticancer Agents Med Chem. 21:20–32.
2021. View Article : Google Scholar : PubMed/NCBI
|
35
|
Sakai W, Yuasa-Sunagawa M, Kusakabe M,
Kishimoto A, Matsui T, Kaneko Y, Akagi JI, Huyghe N, Ikura M, Ikura
T, et al: Functional impacts of the ubiquitin-proteasome system on
DNA damage recognition in global genome nucleotide excision repair.
Sci Rep. 10:197042020. View Article : Google Scholar : PubMed/NCBI
|
36
|
Zhu R, Liu Y, Zhou H, Li L, Li Y, Ding F,
Cao X and Liu Z: Deubiquitinating enzyme PSMD14 promotes tumor
metastasis through stabilizing SNAIL in human esophageal squamous
cell carcinoma. Cancer Lett. 418:125–134. 2018. View Article : Google Scholar : PubMed/NCBI
|
37
|
Seo D, Jung SM, Park JS, Lee J, Ha J, Kim
M and Park SH: The deubiquitinating enzyme PSMD14 facilitates tumor
growth and chemoresistance through stabilizing the ALK2 receptor in
the initiation of BMP6 signaling pathway. EbioMedicine. 49:55–71.
2019. View Article : Google Scholar : PubMed/NCBI
|
38
|
Fire A, Xu S, Montgomery MK, Kostas SA,
Driver SE and Mello CC: Potent and specific genetic interference by
double-stranded RNA in Caenorhabditis elegans. Nature. 391:806–811.
1998. View Article : Google Scholar : PubMed/NCBI
|
39
|
Yao T and Cohen RE: A cryptic protease
couples deubiquitination and degradation by the proteasome. Nature.
419:403–407. 2002. View Article : Google Scholar : PubMed/NCBI
|
40
|
Vyas S, Zaganjor E and Haigis MC:
Mitochondria and cancer. Cell. 166:555–566. 2016. View Article : Google Scholar : PubMed/NCBI
|
41
|
Dai W and Jiang L: Dysregulated
mitochondrial dynamics and metabolism in obesity, diabetes, and
cancer. Front Endocrinol (Lausanne). 10:5702019. View Article : Google Scholar : PubMed/NCBI
|
42
|
Chan DC: Mitochondrial dynamics and its
involvement in disease. Annu Rev Pathol. 15:235–259. 2020.
View Article : Google Scholar : PubMed/NCBI
|
43
|
Rodrigues T and Ferraz LS: Therapeutic
potential of targeting mitochondrial dynamics in cancer. Biochem
Pharmacol. 182:1142822020. View Article : Google Scholar : PubMed/NCBI
|
44
|
Deng X, Liu J, Liu L, Sun X, Huang J and
Dong J: Drp1-mediated mitochondrial fission contributes to
baicalein-induced apoptosis and autophagy in lung cancer via
activation of AMPK signaling pathway. Int J Biol Sci. 16:1403–1416.
2020. View Article : Google Scholar : PubMed/NCBI
|
45
|
Moghaddam FD, Mortazavi P, Hamedi S,
Nabiuni M and Roodbari NH: Apoptotic effects of melittin on 4T1
breast cancer cell line is associated with up regulation of Mfn1
and Drp1 mRNA expression. Anticancer Agents Med Chem. 20:790–799.
2020. View Article : Google Scholar : PubMed/NCBI
|
46
|
Zhan L, Cao H, Wang G, Lyu Y, Sun X, An J,
Wu Z, Huang Q, Liu B and Xing J: Drp1-mediated mitochondrial
fission promotes cell proliferation through crosstalk of p53 and
NF-κB pathways in hepatocellular carcinoma. Oncotarget.
7:65001–65011. 2016. View Article : Google Scholar : PubMed/NCBI
|
47
|
Hu J, Zhang Y, Jiang X, Zhang H, Gao Z, Li
Y, Fu R, Li L, Li J, Cui H and Gao N: ROS-mediated activation and
mitochondrial translocation of CaMKII contributes to Drp1-dependent
mitochondrial fission and apoptosis in triple-negative breast
cancer cells by isorhamnetin and chloroquine. J Exp Clin Cancer
Res. 38:2252019. View Article : Google Scholar : PubMed/NCBI
|
48
|
Mitra K, Wunder C, Roysam B, Lin G and
Lippincott-Schwartz J: A hyperfused mitochondrial state achieved at
G1-S regulates cyclin E buildup and entry into S phase. Proc Natl
Acad Sci USA. 106:11960–11965. 2009. View Article : Google Scholar : PubMed/NCBI
|
49
|
Liang J, Yang Y, Bai L, Li F and Li E:
DRP1 upregulation promotes pancreatic cancer growth and metastasis
through increased aerobic glycolysis. J Gastroenterol Hepatol.
35:885–895. 2020. View Article : Google Scholar : PubMed/NCBI
|
50
|
Kitamura S, Yanagi T, Imafuku K, Hata H,
Abe R and Shimizu H: Drp1 regulates mitochondrial morphology and
cell proliferation in cutaneous squamous cell carcinoma. J Dermatol
Sci. 88:298–307. 2017. View Article : Google Scholar : PubMed/NCBI
|
51
|
Xie Q, Wu Q, Horbinski CM, Flavahan WA,
Yang K, Zhou W, Dombrowski SM, Huang Z, Fang X, Shi Y, et al:
Mitochondrial control by DRP1 in brain tumor initiating cells. Nat
Neurosci. 18:501–510. 2015. View Article : Google Scholar : PubMed/NCBI
|
52
|
Zhao J, Zhang J, Yu M, Xie Y, Huang Y,
Wolff DW, Abel PW and Tu Y: Mitochondrial dynamics regulates
migration and invasion of breast cancer cells. Oncogene.
32:4814–4824. 2013. View Article : Google Scholar : PubMed/NCBI
|
53
|
Rehman J, Zhang HJ, Toth PT, Zhang Y,
Marsboom G, Hong Z, Salgia R, Husain AN, Wietholt C and Archer SL:
Inhibition of mitochondrial fission prevents cell cycle progression
in lung cancer. FASEB J. 26:2175–2186. 2012. View Article : Google Scholar : PubMed/NCBI
|