1
|
Kujala E, Mäkitie T and Kivelä T: Very
long-term prognosis of patients with malignant uveal melanoma.
Invest Ophth Vis Sci. 44:4651–4659. 2003. View Article : Google Scholar : PubMed/NCBI
|
2
|
Augsburger JJ, Correa ZM and Shaikh AH:
Effectiveness of treatments for metastatic uveal melanoma. Am J
Ophthalmol. 148:119–127. 2009. View Article : Google Scholar : PubMed/NCBI
|
3
|
Smit KN, Jager MJ, de Klein A and Kiliҫ E:
Uveal melanoma: Towards a molecular understanding. Prog Retin Eye
Res. 75:1008002020. View Article : Google Scholar : PubMed/NCBI
|
4
|
Onken MD, Worley LA, Ehlers JP and Harbour
JW: Gene expression profiling in uveal melanoma reveals two
molecular classes and predicts metastatic death. Cancer Res.
64:7205–7209. 2004. View Article : Google Scholar : PubMed/NCBI
|
5
|
Zhang X, Bai XC and Chen ZJ: Structures
and mechanisms in the cGAS-STING innate immunity pathway. Immunity.
53:43–53. 2020. View Article : Google Scholar : PubMed/NCBI
|
6
|
Falahat R, Perez-Villarroel P, Mailloux
AW, Zhu G, Pilon-Thomas S, Barber GN and Mulé JJ: STING signaling
in melanoma cells shapes antigenicity and can promote antitumor
T-cell activity. Cancer Immunol Res. 7:1837–1848. 2019. View Article : Google Scholar : PubMed/NCBI
|
7
|
Xia T, Konno H, Ahn J and Barber GN:
Deregulation of STING signaling in colorectal carcinoma constrains
DNA damage responses and correlates with tumorigenesis. Cell Rep.
14:282–297. 2016. View Article : Google Scholar : PubMed/NCBI
|
8
|
Pantelidou C, Sonzogni O, De Oliveria
Taveira M, Mehta AK, Kothari A, Wang D, Visal T, Li MK, Pinto J,
Castrillon JA, et al: PARP inhibitor efficacy depends on
CD8+ T-cell recruitment via intratumoral STING pathway
activation in BRCA-deficient models of triple-negative breast
cancer. Cancer Discov. 9:722–737. 2019. View Article : Google Scholar : PubMed/NCBI
|
9
|
Liang D, Xiao-Feng H, Guan-Jun D, Er-Ling
H, Sheng C, Ting-Ting W, Qin-Gang H, Yan-Hong N and Ya-Yi H:
Activated STING enhances Tregs infiltration in the HPV-related
carcinogenesis of tongue squamous cells via the c-jun/CCL22 signal.
Biochim Biophys Acta. 1852:2494–2503. 2015. View Article : Google Scholar : PubMed/NCBI
|
10
|
Ahn J, Xia T, Konno H, Konno K, Ruiz P and
Barber GN: Inflammation-driven carcinogenesis is mediated through
STING. Nat Commun. 5:51662014. View Article : Google Scholar : PubMed/NCBI
|
11
|
Cai H, Yan L, Liu N, Xu M and Cai H: IFI16
promotes cervical cancer progression by upregulating PD-L1 in
immunomicroenvironment through STING-TBK1-NF-kB pathway. Biomed
Pharmacother. 123:1097902020. View Article : Google Scholar : PubMed/NCBI
|
12
|
Dai E, Han L, Liu J, Xie Y, Zeh HJ, Kang
R, Bai L and Tang D: Ferroptotic damage promotes pancreatic
tumorigenesis through a TMEM173/STING-dependent DNA sensor pathway.
Nat Commun. 11:63392020. View Article : Google Scholar : PubMed/NCBI
|
13
|
Bakhoum SF, Ngo B, Laughney AM, Cavallo
JA, Murphy CJ, Ly P, Shah P, Sriram RK, Watkins TBK, Taunk NK, et
al: Chromosomal instability drives metastasis through a cytosolic
DNA response. Nature. 553:467–472. 2018. View Article : Google Scholar : PubMed/NCBI
|
14
|
Tang Z, Li C, Kang B, Gao G, Li C and
Zhang Z: GEPIA: A web server for cancer and normal gene expression
profiling and interactive analyses. Nucleic Acids Res. 45:W98–W102.
2017. View Article : Google Scholar : PubMed/NCBI
|
15
|
Hamm M, Ha S and Rustandi RR: Automated
capillary Western dot blot method for the identity of a 15-valent
pneumococcal conjugate vaccine. Anal Biochem. 478:33–39. 2015.
View Article : Google Scholar : PubMed/NCBI
|
16
|
Wang J, Valdez A and Chen Y: Evaluation of
automated Wes system as an analytical and characterization tool to
support monoclonal antibody drug product development. J Pharm
Biomed Anal. 139:263–268. 2017. View Article : Google Scholar : PubMed/NCBI
|
17
|
Borcherding DC, Amin NV, He K, Zhang X,
Lyu Y, Dehner C, Bhatia H, Gothra A, Daud L, Ruminski P, et al: MEK
inhibition synergizes with TYK2 inhibitors in NF1-associated
malignant peripheral nerve sheath tumors. Clin Cancer Res.
29:1592–1604. 2023. View Article : Google Scholar : PubMed/NCBI
|
18
|
Neelature SS and Smalley K: MEK-ing the
most of it: Strategies to Co-target Gαq and MAPK in uveal melanoma.
Clin Cancer Res. 27:1217–1219. 2021. View Article : Google Scholar : PubMed/NCBI
|
19
|
Szalai E, Wells JR, Ward L and
Grossniklaus HE: Uveal melanoma nuclear BRCA1-associated Protein-1
immunoreactivity is an indicator of metastasis. Ophthalmology.
125:203–209. 2018. View Article : Google Scholar : PubMed/NCBI
|
20
|
Wang J, Yi S, Zhou J, Zhang Y and Guo F:
The NF-κB subunit RelB regulates the migration and invasion
abilities and the radio-sensitivity of prostate cancer cells. Int J
Oncol. 49:381–392. 2016. View Article : Google Scholar : PubMed/NCBI
|
21
|
Wang X, Belguise K, Kersual N, Kirsch KH,
Mineva ND, Galtier F, Chalbos D and Sonenshein GE: Oestrogen
signalling inhibits invasive phenotype by repressing RelB and its
target BCL2. Nat Cell Biol. 9:470–478. 2007. View Article : Google Scholar : PubMed/NCBI
|
22
|
Deng L, Liang H, Xu M, Yang X, Burnette B,
Arina A, Li XD, Mauceri H, Beckett M, Darga T, et al:
STING-dependent cytosolic DNA sensing promotes radiation-induced
type I interferon-dependent antitumor immunity in immunogenic
tumors. Immunity. 41:843–852. 2014. View Article : Google Scholar : PubMed/NCBI
|
23
|
Ding L, Wang Q, Martincuks A, Kearns MJ,
Jiang T, Lin Z, Cheng X, Qian C, Xie S, Kim HJ, et al: STING
agonism overcomes STAT3-mediated immunosuppression and adaptive
resistance to PARP inhibition in ovarian cancer. J Immunother
Cancer. 11:e0056272023. View Article : Google Scholar : PubMed/NCBI
|
24
|
He L, Xiao X, Yang X, Zhang Z, Wu L and
Liu Z: STING signaling in tumorigenesis and cancer therapy: A
friend or foe? Cancer Lett. 402:203–212. 2017. View Article : Google Scholar : PubMed/NCBI
|
25
|
Viculin J, Degoricija M, Vilović K, Gabela
I, Franković L, Vrdoljak E and Korac-Prlic J: Elevated tumor
cell-intrinsic STING expression in advanced laryngeal cancer.
Cancers (Basel). 15:35102023. View Article : Google Scholar : PubMed/NCBI
|
26
|
Song S, Peng P, Tang Z, Zhao J, Wu W, Li
H, Shao M, Li L, Yang C, Duan F, et al: Decreased expression of
STING predicts poor prognosis in patients with gastric cancer. Sci
Rep. 7:398582017. View Article : Google Scholar : PubMed/NCBI
|
27
|
Lu C, Guan J, Lu S, Jin Q, Rousseau B, Lu
T, Stephens D, Zhang H, Zhu J, Yang M, et al: DNA sensing in
mismatch Repair-deficient tumor cells is essential for Anti-tumor
immunity. Cancer Cell. 39:96–108. 2021. View Article : Google Scholar : PubMed/NCBI
|
28
|
Parkes EE, Humphries MP, Gilmore E, Sidi
FA, Bingham V, Phyu SM, Craig S, Graham C, Miller J, Griffin D, et
al: The clinical and molecular significance associated with STING
signaling in breast cancer. NPJ Breast Cancer. 7:812021. View Article : Google Scholar : PubMed/NCBI
|
29
|
Zhang Y, Zhai Q, Feng X, Chen D, Lu Y, Hu
J, Xie H, Zhou L, Wu J and Zheng S: Cancer cell-intrinsic STING is
associated with CD8 + T-cell infiltration and might serve as a
potential immunotherapeutic target in hepatocellular carcinoma.
Clin Transl Oncol. 23:1314–1324. 2021. View Article : Google Scholar : PubMed/NCBI
|
30
|
Kol A, Lubbers JM, Terwindt ALJ, Workel
HH, Plat A, Wisman GBA, Bart J, Nijman HW and De Bruyn M: Combined
STING levels and CD103+ T cell infiltration have significant
prognostic implications for patients with cervical cancer.
Oncoimmunology. 10:19363912021. View Article : Google Scholar : PubMed/NCBI
|
31
|
Cheradame L, Guerrera IC, Gaston J,
Schmitt A, Jung V, Goudin N, Pouillard M, Radosevic-Robin N,
Modesti M, Judde JG, et al: STING protects breast cancer cells from
intrinsic and genotoxic-induced DNA instability via a
non-canonical, cell-autonomous pathway. Oncogene. 40:6627–6640.
2021. View Article : Google Scholar : PubMed/NCBI
|
32
|
Huvila J, Cochrane DR, Ta M, Chow C,
Greening K, Leung S, Karnezis AN, DiFeo A and Huntsman DG: STING
pathway expression in low-grade serous carcinoma of the ovary: An
unexpected therapeutic opportunity? J Pathol Clin Res. 7:548–555.
2021. View Article : Google Scholar : PubMed/NCBI
|
33
|
Zhang H, You Q and Xu X: Targeting
stimulator of interferon genes (STING): A medicinal chemistry
perspective. J Med Chem. 63:3785–3816. 2020. View Article : Google Scholar : PubMed/NCBI
|
34
|
Chen Q, Boire A, Jin X, Valiente M, Er EE,
Lopez-Soto A, Jacob L, Patwa R, Shah H, Xu K, et al:
Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP
transfer. Nature. 533:493–498. 2016. View Article : Google Scholar : PubMed/NCBI
|
35
|
Niederkorn JY: Immune escape mechanisms of
intraocular tumors. Prog Retin Eye Res. 28:329–347. 2009.
View Article : Google Scholar : PubMed/NCBI
|
36
|
Bakhoum MF, Francis JH, Agustinus A,
Earlie EM, Di Bona M, Abramson DH, Duran M, Masilionis I, Molina E,
Shoushtari AN, et al: Loss of polycomb repressive complex 1
activity and chromosomal instability drive uveal melanoma
progression. Nat Commun. 12:54022021. View Article : Google Scholar : PubMed/NCBI
|
37
|
Hitchman TD, Bayshtok G, Ceraudo E, Moore
AR, Lee C, Jia R, Wang N, Pachai MR, Shoushtari AN, Francis JH, et
al: Combined inhibition of Gα(q) and MEK enhances therapeutic
efficacy in uveal melanoma. Clin Cancer Res. 27:1476–1490. 2021.
View Article : Google Scholar : PubMed/NCBI
|
38
|
Wagner EF and Nebreda AR: Signal
integration by JNK and p38 MAPK pathways in cancer development. Nat
Rev Cancer. 9:537–549. 2009. View Article : Google Scholar : PubMed/NCBI
|
39
|
Hsieh Y, Wu T, Huang C, Hsieh Y, Hwang J
and Liu J: p38 mitogen-activated protein kinase pathway is involved
in protein kinase C alpha-regulated invasion in human
hepatocellular carcinoma cells. Cancer Res. 67:4320–4327. 2007.
View Article : Google Scholar : PubMed/NCBI
|
40
|
Junttila MR, Ala-Aho R, Jokilehto T,
Peltonen J, Kallajoki M, Grenman R, Jaakkola P, Westermarck J and
Kähäri V-M: p38alpha and p38delta mitogen-activated protein kinase
isoforms regulate invasion and growth of head and neck squamous
carcinoma cells. Oncogene. 26:5267–5279. 2007. View Article : Google Scholar : PubMed/NCBI
|
41
|
Demuth T, Reavie LB, Rennert JL, Nakada M,
Nakada S, Hoelzinger DB, Beaudry CE, Henrichs AN, Anderson EM and
Berens ME: MAP-ing glioma invasion: mitogen-activated protein
kinase kinase 3 and p38 drive glioma invasion and progression and
predict patient survival. Mol Cancer Ther. 6:1212–1222. 2007.
View Article : Google Scholar : PubMed/NCBI
|
42
|
Li J-K, Chen C, Liu J-Y, Shi J-Z, Liu S-P,
Liu B, Wu D-S, Fang Z-Y, Bao Y, Jiang M-M, et al: Long noncoding
RNA MRCCAT1 promotes metastasis of clear cell renal cell carcinoma
via inhibiting NPR3 and activating p38-MAPK signaling. Mol Cancer.
16:1112017. View Article : Google Scholar : PubMed/NCBI
|
43
|
Huang Q, Lan F, Wang X, Yu Y, Ouyang X,
Zheng F, Han J, Lin Y, Xie Y, Xie F, et al: IL-1β-induced
activation of p38 promotes metastasis in gastric adenocarcinoma via
upregulation of AP-1/c-fos, MMP2 and MMP9. Mol Cancer. 13:182014.
View Article : Google Scholar : PubMed/NCBI
|
44
|
Hu DN, Chen M, Zhang DY, Ye F, McCormick
SA and Chan CC: Interleukin-1beta increases baseline expression and
secretion of interleukin-6 by human uveal melanocytes in vitro via
the p38 MAPK/NF-kappaB pathway. Invest Ophthalmol Vis Sci.
52:3767–3774. 2011. View Article : Google Scholar : PubMed/NCBI
|
45
|
Gong C, Shen J, Fang Z, et al: Abnormally
expressed JunB transactivated by IL-6/STAT3 signaling promotes
uveal melanoma aggressiveness via epithelial-mesenchymal
transition. Biosci Rep. 38:2018. View Article : Google Scholar
|
46
|
Tao H, Tan J, Zhang H, Ren H, Cai Z, Liu
H, Wen B, Du J, Li G, Chen S, et al: cGAS-STING pathway activation
and systemic anti-tumor immunity induction via photodynamic
nanoparticles with potent toxic platinum DNA intercalator against
uveal melanoma. Adv Sci (Weinh). e23028952023. View Article : Google Scholar : PubMed/NCBI
|