Chronic myeloid leukemia treated with busulfan

  • Authors:
    • P Foa
    • A Iurlo
    • S Ribera
    • I DaMilano
    • S Caldiera
    • M Fornier
    • F Bertoni
    • A Maiolo
  • View Affiliations

  • Published online on: November 1, 1996     https://doi.org/10.3892/or.3.6.1067
  • Pages: 1067-1069
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Abstract

Interferon alpha is presently viewed as the first choice drug for treatment of chronic myeloid leukemia; however patients who are not eligible for this type of therapy are still treated with conventional chemotherapeutic agents as for instance hydroxyurea and/or busulfan. In a series of 23 patients with Philadelphia chromosome positive chronic myeloid leukemia who have been treated solely with busulfan, we have evaluated the relationship between total amount of drug required during the first 12 months of treatment and duration of the chronic phase. A statistically significant (p<0.005) inverse relationship between these two parameters was found, indicating that patients with low busulfan requirement during the first year of therapy have a better prognosis.

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November 1996
Volume 3 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Foa P, Iurlo A, Ribera S, DaMilano I, Caldiera S, Fornier M, Bertoni F and Maiolo A: Chronic myeloid leukemia treated with busulfan. Oncol Rep 3: 1067-1069, 1996.
APA
Foa, P., Iurlo, A., Ribera, S., DaMilano, I., Caldiera, S., Fornier, M. ... Maiolo, A. (1996). Chronic myeloid leukemia treated with busulfan. Oncology Reports, 3, 1067-1069. https://doi.org/10.3892/or.3.6.1067
MLA
Foa, P., Iurlo, A., Ribera, S., DaMilano, I., Caldiera, S., Fornier, M., Bertoni, F., Maiolo, A."Chronic myeloid leukemia treated with busulfan". Oncology Reports 3.6 (1996): 1067-1069.
Chicago
Foa, P., Iurlo, A., Ribera, S., DaMilano, I., Caldiera, S., Fornier, M., Bertoni, F., Maiolo, A."Chronic myeloid leukemia treated with busulfan". Oncology Reports 3, no. 6 (1996): 1067-1069. https://doi.org/10.3892/or.3.6.1067