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Clinical significance of serum c-erbB-2 protein in patients with primary breast cancer

  • Authors:
    • H Takahashi
    • S Sasaki
    • Y Okawa
    • K Taguchi
    • F Sasaki
    • J Uchino
    • Y Hata
    • M Fujita
    • K Nagashima
    • Y Ito
    • T Kawai

  • View Affiliations

  • Published online on: March 1, 1997     https://doi.org/10.3892/or.4.2.349
  • Pages: 349-352
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
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Abstract

We measured serum c-erbB-2 protein concentration in 167 patients with primary breast cancer. The rate of positive results was 6%. The positivity rate of serum c-erbB-2 protein did not differ among stages I, II, IIIa and IIIb. However the positivity rate on stage IV was 50% (3/6) and significantly higher than the other stages (p=0.0006). The rate of;positive results correlated significantly with lymph node status (p=0.0037). We concluded that the level of serum c-erbB-2 protein reflected the malignant characteristics of primary breast cancer and its measurement may be useful for a preoperative evaluation of primary breast cancer.

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March 1997
Volume 4 Issue 2

Print ISSN: 1021-335X
Online ISSN:1791-2431

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  • Impact Factor: 3.8
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  • CiteScore: 8.5
  • CiteScore Rank: Q1: #74/404 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.719
  • SCImago Journal Rank (SJR): 0.864
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Spandidos Publications style
Takahashi H, Sasaki S, Okawa Y, Taguchi K, Sasaki F, Uchino J, Hata Y, Fujita M, Nagashima K, Ito Y, Ito Y, et al: Clinical significance of serum c-erbB-2 protein in patients with primary breast cancer. Oncol Rep 4: 349-352, 1997.
APA
Takahashi, H., Sasaki, S., Okawa, Y., Taguchi, K., Sasaki, F., Uchino, J. ... Kawai, T. (1997). Clinical significance of serum c-erbB-2 protein in patients with primary breast cancer. Oncology Reports, 4, 349-352. https://doi.org/10.3892/or.4.2.349
MLA
Takahashi, H., Sasaki, S., Okawa, Y., Taguchi, K., Sasaki, F., Uchino, J., Hata, Y., Fujita, M., Nagashima, K., Ito, Y., Kawai, T."Clinical significance of serum c-erbB-2 protein in patients with primary breast cancer". Oncology Reports 4.2 (1997): 349-352.
Chicago
Takahashi, H., Sasaki, S., Okawa, Y., Taguchi, K., Sasaki, F., Uchino, J., Hata, Y., Fujita, M., Nagashima, K., Ito, Y., Kawai, T."Clinical significance of serum c-erbB-2 protein in patients with primary breast cancer". Oncology Reports 4, no. 2 (1997): 349-352. https://doi.org/10.3892/or.4.2.349