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Mutational analysis of the PTEN/MMAC1 tumour suppressor gene in primary human malignant mesotheliomas

  • Authors:
    • Thilo Papp
    • Holger Schipper
    • Heidi Pemsel
    • Marcus Unverricht
    • Klaus-Michael Muller
    • Thorsten Wiethege
    • Dietmar Schiffmann
    • Qamar Rahman

  • View Affiliations

  • Published online on: November 1, 2001     https://doi.org/10.3892/or.8.6.1375
  • Pages: 1375-1379
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Abstract

Eighteen primary human malignant mesotheliomas obtained from 18 patients were screened for point mutations and microdeletions/insertions in all exons of the tumour suppressor gene PTEN/MMAC1 by SSCP analysis. No mutation could be found. Our preliminary data indicate that disarrangements of PTEN/MMAC1 are at least not frequently involved in mesothelioma formation.

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November-December 2001
Volume 8 Issue 6

Print ISSN: 1021-335X
Online ISSN:1791-2431

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  • Journal Metrics
  • Impact Factor: 3.8
  • Ranked Oncology
    (total number of cites)
  • CiteScore: 8.5
  • CiteScore Rank: Q1: #74/404 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.719
  • SCImago Journal Rank (SJR): 0.864
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Spandidos Publications style
Papp T, Schipper H, Pemsel H, Unverricht M, Muller K, Wiethege T, Schiffmann D and Rahman Q: Mutational analysis of the PTEN/MMAC1 tumour suppressor gene in primary human malignant mesotheliomas. Oncol Rep 8: 1375-1379, 2001.
APA
Papp, T., Schipper, H., Pemsel, H., Unverricht, M., Muller, K., Wiethege, T. ... Rahman, Q. (2001). Mutational analysis of the PTEN/MMAC1 tumour suppressor gene in primary human malignant mesotheliomas. Oncology Reports, 8, 1375-1379. https://doi.org/10.3892/or.8.6.1375
MLA
Papp, T., Schipper, H., Pemsel, H., Unverricht, M., Muller, K., Wiethege, T., Schiffmann, D., Rahman, Q."Mutational analysis of the PTEN/MMAC1 tumour suppressor gene in primary human malignant mesotheliomas". Oncology Reports 8.6 (2001): 1375-1379.
Chicago
Papp, T., Schipper, H., Pemsel, H., Unverricht, M., Muller, K., Wiethege, T., Schiffmann, D., Rahman, Q."Mutational analysis of the PTEN/MMAC1 tumour suppressor gene in primary human malignant mesotheliomas". Oncology Reports 8, no. 6 (2001): 1375-1379. https://doi.org/10.3892/or.8.6.1375