1
|
Gelbart WM, Lewontin RC, Wessler SR,
Suzuki DT, Miller JH and Griffiths AJF: An Introduction to Genetic
Analysis, 8th edition. W.H.Freeman & Co Ltd. 2004.
|
2
|
Bray F, Ferlay J, Soerjomataram I, Siegel
RL, Torre LA and Jemal A: Global cancer statistics 2018: GLOBOCAN
estimates of incidence and mortality worldwide for 36 cancers in
185 countries. CA Cancer J Clin. 68:394–424. 2018.PubMed/NCBI View Article : Google Scholar
|
3
|
Arem H and Loftfield E: Cancer
epidemiology: A survey of modifiable risk factors for prevention
and survivorship. Am J Lifestyle Med. 12:200–210. 2017.PubMed/NCBI View Article : Google Scholar
|
4
|
Theodoratou E, Timofeeva M, Li X, Meng X
and Ioannidis JPA: Nature, nurture, and cancer risks: Genetic and
nutritional contributions to cancer. Annu Rev Nutr. 37:293–320.
2017.PubMed/NCBI View Article : Google Scholar
|
5
|
Wu S, Zhu W, Thompson P and Hannun YA:
Evaluating intrinsic and non-intrinsic cancer risk factors. Nat
Commun. 9(3490)2018.PubMed/NCBI View Article : Google Scholar
|
6
|
Tripathi KD: Essentials of Medical
Pharmacology, 7th edition. Jaypee Brothers Medical Publishers (P)
Ltd, 2013.
|
7
|
Steward WP and Brown K: Cancer
chemoprevention: A rapidly evolving field. Br J Cancer.
109(17)2013.PubMed/NCBI View Article : Google Scholar
|
8
|
Aggarwal BB, Takada Y and Oommen OV: From
chemoprevention to chemotherapy: Common targets and common goals.
Expert Opin Investig Drugs. 13:1327–1338. 2004.PubMed/NCBI View Article : Google Scholar
|
9
|
Patterson SL, Colbert Maresso K and Hawk
E: Cancer chemoprevention: Successes and failures. Clin Chem.
59:94–101. 2013.PubMed/NCBI View Article : Google Scholar
|
10
|
Sauter ER: Breast cancer prevention:
current approaches and future directions. Eur J Breast Health.
14:64–71. 2018.PubMed/NCBI View Article : Google Scholar
|
11
|
de Melo FHM, Oliveira JS, Sartorelli VOB
and Montor WR: Cancer chemoprevention: Classic and epigenetic
mechanisms inhibiting tumorigenesis. What have we learned so far?
Front Oncol. 8(644)2018.PubMed/NCBI View Article : Google Scholar
|
12
|
Heller MC, Keoleian GA and Willett WC:
Toward a life cycle-based, diet-level framework for food
environmental impact and nutritional quality assessment: A critical
review. Environ Sci Technol. 47:12632–12647. 2013.PubMed/NCBI View Article : Google Scholar
|
13
|
Zhou Y, Zheng J, Li Y, Xu DP, Li S, Chen
YM and Li HB: Natural polyphenols for prevention and treatment of
cancer. Nutrients. 8(E515)2016.PubMed/NCBI View Article : Google Scholar
|
14
|
Costea T, Hudiță A, Ciolac OA, Gălățeanu
B, Ginghină O, Costache M, Ganea C and Mocanu MM: Chemoprevention
of colorectal cancer by dietary compounds. Int J Mol Sci.
19(E3787)2018.PubMed/NCBI View Article : Google Scholar
|
15
|
Petrick JL, Steck SE, Bradshaw PT, Trivers
KF, Abrahamson PE, Engel LS, He K, Chow WH, Mayne ST, Risch HA, et
al: Dietary intake of flavonoids and oesophageal and gastric
cancer: Incidence and survival in the United States of America
(USA). Br J Cancer. 112:1291–1300. 2015.PubMed/NCBI View Article : Google Scholar
|
16
|
Wang ZJ, Ohnaka K, Morita M, Toyomura K,
Kono S, Ueki T, Tanaka M, Kakeji Y, Maehara Y, Okamura T, et al:
Dietary polyphenols and colorectal cancer risk: The Fukuoka
colorectal cancer study. World J Gastroenterol. 19:2683–2690.
2013.PubMed/NCBI View Article : Google Scholar
|
17
|
Koosha S, Alshawsh MA, Looi CY, Seyedan A
and Mohamed Z: An association map on the effect of flavonoids on
the signaling pathways in colorectal cancer. Int J Med Sci.
13:374–385. 2016.PubMed/NCBI View Article : Google Scholar
|
18
|
Yan X, Qi M, Li P, Zhan Y and Shao H:
Apigenin in cancer therapy: Anti-cancer effects and mechanisms of
action. Cell Biosci. 7(50)2017.PubMed/NCBI View Article : Google Scholar
|
19
|
Lin CH, Chang CY, Lee KR, Lin HJ, Chen TH
and Wan L: Flavones inhibit breast cancer proliferation through the
Akt/FOXO3a signaling pathway. BMC Cancer. 15(958)2015.PubMed/NCBI View Article : Google Scholar
|
20
|
Amawi H, Ashby CR Jr and Tiwari AK: Cancer
chemoprevention through dietary flavonoids : What's limiting? Chin
J Cancer. 36(50)2017.PubMed/NCBI View Article : Google Scholar
|
21
|
Moga MA, Dimienescu OG, Arvatescu CA,
Mironescu A, Dracea L and Ples L: The role of natural polyphenols
in the prevention and treatment of cervical cancer-an overview.
Molecules. 21(E1055)2016.PubMed/NCBI View Article : Google Scholar
|
22
|
Landis-Piwowar KR, Milacic V and Dou QP:
Relationship between the methylation status of dietary flavonoids
and their growth-inhibitory and apoptosis-inducing activities in
human cancer cells. J Cell Biochem. 105:514–523. 2008.PubMed/NCBI View Article : Google Scholar
|
23
|
Ryu S, Lim W, Bazer FW and Song G: Chrysin
induces death of prostate cancer cells by inducing ROS and ER
stress. J Cell Physiol. 232:3786–3797. 2017.PubMed/NCBI View Article : Google Scholar
|
24
|
Lim W, Ryu S, Bazer FW, Kim SM and Song G:
Chrysin attenuates progression of ovarian cancer cells by
regulating signaling cascades and mitochondrial dysfunction. J Cell
Physiol. 233:3129–3140. 2018.PubMed/NCBI View Article : Google Scholar
|
25
|
Granato M, Gilardini Montani MS,
Santarelli R, D'Orazi G, Faggioni A and Cirone M: Apigenin, by
activating p53 and inhibiting STAT3, modulates the balance between
pro-apoptotic and pro-survival pathways to induce PEL cell death. J
Exp Clin Cancer Res. 36(167)2017.PubMed/NCBI View Article : Google Scholar
|
26
|
Romagnolo DF, Donovan MG, Papoutsis AJ,
Doetschman TC and Selmin OI: Genistein prevents BRCA1 CpG
methylation and proliferation in human breast cancer cells with
activated aromatic hydrocarbon receptor. Curr Dev Nutr.
1(e000562)2017.PubMed/NCBI View Article : Google Scholar
|
27
|
Souza RP, Bonfim-Mendonça PS, Gimenes F,
Ratti BA, Kaplum V, Bruschi ML, Nakamura CV, Silva SO, Maria-Engler
SS and Consolaro ME: Oxidative stress triggered by apigenin induces
apoptosis in a comprehensive panel of human cervical cancer-derived
cell lines. Oxid Med Cell Longev. 2017(1512745)2017.PubMed/NCBI View Article : Google Scholar
|
28
|
Sung B, Chung HY and Kim ND: Role of
apigenin in cancer prevention via the induction of apoptosis and
autophagy. J Cancer Prev. 21:216–226. 2016.PubMed/NCBI View Article : Google Scholar
|
29
|
Ci Y, Qiao J and Han M: Molecular
mechanisms and metabolomics of natural polyphenols interfering with
breast cancer metastasis. Molecules. 21(E1634)2016.PubMed/NCBI View Article : Google Scholar
|
30
|
Xue C, Chen Y, Hu DN, Iacob C, Lu C and
Huang Z: Chrysin induces cell apoptosis in human uveal melanoma
cells via intrinsic apoptosis. Oncol Lett. 12:4813–4820.
2016.PubMed/NCBI View Article : Google Scholar
|
31
|
Xu Y, Tong Y, Ying J, Lei Z, Wan L, Zhu X,
Ye F, Mao P, Wu X, Pan R, et al: Chrysin induces cell growth
arrest, apoptosis, and ER stress and inhibits the activation of
STAT3 through the generation of ROS in bladder cancer cells. Oncol
Lett. 15:9117–9125. 2018.PubMed/NCBI View Article : Google Scholar
|
32
|
Chylińska-Wrzos P, Lis-Sochocka M and
Jodlowska-Jedrych B: Chrysin and its potential antineoplastic
effect. Eur J Biol Res. 7:245–254. 2017.
|
33
|
Ronnekleiv-Kelly SM, Nukaya M, Díaz-Díaz
CJ, Megna BW, Carney PR, Geiger PG and Kennedy GD: Aryl hydrocarbon
receptor-dependent apoptotic cell death induced by the flavonoid
chrysin in human colorectal cancer cells. Cancer Lett. 370:91–99.
2016.PubMed/NCBI View Article : Google Scholar
|
34
|
Zhang Q, Ma S, Liu B, Liu J, Zhu R and Li
M: Chrysin induces cell apoptosis via activation of the
p53/Bcl-2/caspase-9 pathway in hepatocellular carcinoma cells. Exp
Ther Med. 12:469–474. 2016.PubMed/NCBI View Article : Google Scholar
|
35
|
Xu D, Jin J, Yu H, Zhao Z, Ma D, Zhang C
and Jiang H: Chrysin inhibited tumor glycolysis and induced
apoptosis in hepatocellular carcinoma by targeting hexokinase-2. J
Exp Clin Cancer Res. 36(44)2017.PubMed/NCBI View Article : Google Scholar
|
36
|
Wang J, Wang H, Sun K, Wang X, Pan H, Zhu
J, Ji X and Li X: Chrysin suppresses proliferation, migration, and
invasion in glioblastoma cell lines via mediating the ERK/Nrf2
signaling pathway. Drug Des Devel Ther. 12:721–733. 2018.PubMed/NCBI View Article : Google Scholar
|
37
|
Yu XM, Phan T, Patel PN, Jaskula-Sztul R
and Chen H: Chrysin activates Notch1 signaling and suppresses tumor
growth of anaplastic thyroid carcinoma in vitro and in vivo.
Cancer. 119:774–781. 2013.PubMed/NCBI View Article : Google Scholar
|
38
|
Tuorkey MJ: Molecular targets of luteolin
in cancer. Eur J Cancer Prev. 25:65–76. 2016.PubMed/NCBI View Article : Google Scholar
|
39
|
Ham S, Kim KH, Kwon TH, Bak Y, Lee DH,
Song YS, Park SH, Park YS, Kim MS, Kang JW, et al: Luteolin induces
intrinsic apoptosis via inhibition of E6/E7 oncogenes and
activation of extrinsic and intrinsic signaling pathways in
HPV-18-associated cells. Oncol Rep. 31:2683–2691. 2014.PubMed/NCBI View Article : Google Scholar
|
40
|
Chen P, Zhang JY, Sha BB, Ma YE, Hu T, Ma
YC, Sun H, Shi JX, Dong ZM and Li P: Luteolin inhibits cell
proliferation and induces cell apoptosis via down-regulation of
mitochondrial membrane potential in esophageal carcinoma cells EC1
and KYSE450. Oncotarget. 8:27471–27480. 2017.PubMed/NCBI View Article : Google Scholar
|
41
|
Wang H, Luo Y, Qiao T, Wu Z and Huang Z:
Luteolin sensitizes the antitumor effect of cisplatin in
drug-resistant ovarian cancer via induction of apoptosis and
inhibition of cell migration and invasion. J Ovarian Res.
11(93)2018.PubMed/NCBI View Article : Google Scholar
|
42
|
Liao Y, Xu Y, Cao M, Huan Y, Zhu L, Jiang
Y, Shen W and Zhu G: Luteolin induces apoptosis and autophagy in
mouse macrophage ANA-1 cells via the Bcl-2 pathway. J Immunol Res.
2018(4623919)2018.PubMed/NCBI View Article : Google Scholar
|
43
|
Zang M, Hu L, Fan ZY, Wang HX, Zhu ZL, Cao
S, Wu XY, Li JF, Su LP, Li C, et al: Luteolin suppresses gastric
cancer progression by reversing epithelial-mesenchymal transition
via suppression of the Notch signaling pathway. J Transl Med.
15(52)2017.PubMed/NCBI View Article : Google Scholar
|
44
|
Hong Z, Cao X, Li N, Zhang Y, Lan L, Zhou
Y, Pan X, Shen L, Yin Z and Luo L: Luteolin is effective in the
non-small cell lung cancer model with L858R/T790M EGF receptor
mutation and erlotinib resistance. Br J Pharmacol. 171:2842–2853.
2014.PubMed/NCBI View Article : Google Scholar
|
45
|
Liu H, Dong Y, Gao Y, Du Z, Wang Y, Cheng
P, Chen A and Huang H: The fascinating effects of baicalein on
cancer: A review. Int J Mol Sci. 17(E1681)2016.PubMed/NCBI View Article : Google Scholar
|
46
|
Wang Y, Xia J, Tang X, Tang L, Mao X,
Zhang Y and Yu X: Baicalein promotes the apoptosis of HeLa cells by
inhibiting ERK1/2 expression. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
J. 32:1507–1512. 2016.(In Chinese). PubMed/NCBI
|
47
|
Choi EO, Park C, Hwang HJ, Hong SH, Kim
GY, Cho EJ, Kim WJ and Choi YH: Baicalein induces apoptosis via
ROS-dependent activation of caspases in human bladder cancer 5637
cells. Int J Oncol. 49:1009–1018. 2016.PubMed/NCBI View Article : Google Scholar
|
48
|
Yan W, Ma X, Zhao X and Zhang S: Baicalein
induces apoptosis and autophagy of breast cancer cells via
inhibiting PI3K/AKT pathway in vivo and vitro. Drug Des Devel Ther.
12:3961–3972. 2018.PubMed/NCBI View Article : Google Scholar
|
49
|
Peng Y, Guo C, Yang Y, Li F, Zhang Y,
Jiang B and Li Q: Baicalein induces apoptosis of human cervical
cancer HeLa cells in vitro. Mol Med Rep. 11:2129–2134.
2015.PubMed/NCBI View Article : Google Scholar
|
50
|
Ma X, Yan W, Dai Z, Gao X, Ma Y, Xu Q,
Jiang J and Zhang S: Baicalein suppresses metastasis of breast
cancer cells by inhibiting EMT via downregulation of SATB1 and
Wnt/β-catenin pathway. Drug Des Devel Ther. 10:1419–1441.
2016.PubMed/NCBI View Article : Google Scholar
|
51
|
Yu X, Liu Y, Wang Y, Mao X, Zhang Y and
Xia J: Baicalein induces cervical cancer apoptosis through the
NF-κB signaling pathway. Mol Med Rep. 17:5088–5094. 2018.PubMed/NCBI View Article : Google Scholar
|
52
|
Cathcart MC, Useckaite Z, Drakeford C,
Semik V, Lysaght J, Gately K, O'Byrne KJ and Pidgeon GP:
Anti-cancer effects of baicalein in non-small cell lung cancer
in-vitro and in-vivo. BMC Cancer. 16(707)2016.PubMed/NCBI View Article : Google Scholar
|
53
|
Wang Y, Han E, Xing Q, Yan J, Arrington A,
Wang C, Tully D, Kowolik CM, Lu DM, Frankel PH, et al: Baicalein
upregulates DDIT4 expression which mediates mTOR inhibition and
growth inhibition in cancer cells. Cancer Lett. 358:170–179.
2015.PubMed/NCBI View Article : Google Scholar
|
54
|
King JC, Lu QY, Li G, Moro A, Takahashi H,
Chen M, Go VL, Reber HA, Eibl G and Hines OJ: Evidence for
activation of mutated p53 by apigenin in human pancreatic cancer.
Biochim Biophys Acta. 1823:593–604. 2012.PubMed/NCBI View Article : Google Scholar
|
55
|
Shi MD, Shiao CK, Lee YC and Shih YW:
Apigenin, a dietary flavonoid, inhibits proliferation of human
bladder cancer T-24 cells via blocking cell cycle progression and
inducing apoptosis. Cancer Cell Int. 15(33)2015.PubMed/NCBI View Article : Google Scholar
|
56
|
Maeda Y, Takahashi H, Nakai N, Yanagita T,
Ando N, Okubo T, Saito K, Shiga K, Hirokawa T, Hara M, et al:
Apigenin induces apoptosis by suppressing Bcl-xl and Mcl-1
simultaneously via signal transducer and activator of transcription
3 signaling in colon cancer. Int J Oncol. 52:1661–1673.
2018.PubMed/NCBI View Article : Google Scholar
|
57
|
Masuelli L, Benvenuto M, Mattera R, Di
Stefano E, Zago E, Taffera G, Tresoldi I, Giganti MG, Frajese GV,
Berardi G, et al: In vitro and in vivo anti-tumoral effects of the
flavonoid apigenin in malignant mesothelioma. Front Pharmacol.
8(373)2017.PubMed/NCBI View Article : Google Scholar
|
58
|
Subhasitanont P, Chokchaichamnankit D,
Chiablaem K, Keeratichamroen S, Ngiwsara L, Paricharttanakul NM,
Lirdprapamongkol K, Weeraphan C, Svasti J and Srisomsap C: Apigenin
inhibits growth and induces apoptosis in human cholangiocarcinoma
cells. Oncol Lett. 14:4361–4371. 2017.PubMed/NCBI View Article : Google Scholar
|
59
|
Vrhovac Madunic I, Madunić J, Antunović M,
Paradžik M, Garaj-Vrhovac V, Breljak D, Marijanović I and Gajski G:
Apigenin, a dietary flavonoid, induces apoptosis, DNA damage, and
oxidative stress in human breast cancer MCF-7 and MDA MB-231 cells.
Naunyn Schmiedebergs Arch Pharmacol. 391:537–550. 2018.PubMed/NCBI View Article : Google Scholar
|
60
|
Shukla S, Kanwal R, Shankar E, Datt M,
Chance MR, Fu P, MacLennan GT and Gupta S: Apigenin blocks IKKα
activation and suppresses prostate cancer progression. Oncotarget.
6:31216–31232. 2015.PubMed/NCBI View Article : Google Scholar
|
61
|
Shukla S, Bhaskaran N, Babcook MA, Fu P,
Maclennan GT and Gupta S: Apigenin inhibits prostate cancer
progression in TRAMP mice via targeting PI3K/Akt/FoxO pathway.
Carcinogenesis. 35:452–460. 2014.PubMed/NCBI View Article : Google Scholar
|