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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2005 Volume 16 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Repetitive and safe transgene expression in rat liver is achievable by adenoviral infusion into the common bile duct

Shigeki Kuriyama, Hitoshi Yoshiji, Kentaro Tominaga, Hirohisa Tsujinoue, Toshiya Nakatani, Tatsuhiro Tsujimoto, Hirotsugu Okuda, Takemi Akahane, Akihiro Deguchi, Seiji Nakai, Tsutomu Masaki, Naohito Uchida
Pages: 503-508
Published online on: 01 October 2005

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Article

Human chondrocytes differentially express matrix modulators during in vitro expansion for tissue engineering

Ulrich Reinhart Goessler, Karen Bieback, Peter Bugert, Ramin Naim, Carsten Schafer, Haneen Sadick, Karl Hormann, Frank Riedel
Pages: 509-515
Published online on: 01 October 2005

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Article

Neolignans from Saururus chinensis inhibit PC-3 prostate cancer cell growth via apoptosis and senescence-like mechanisms

Seo-Young Song, Inkyoung Lee, Chaehwa Park, Hyeon Lee, Jong-Cheon Hahm, Won Ki Kang
Pages: 517-523
Published online on: 01 October 2005

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Article

Transient expression of keratin 19 is induced in originally negative interfollicular epidermal cells by adhesion of suspended cells

Barbora DvoRánková, Karel Smetana, Martin Chovanec, LukáS Lacina, Jirí Stork, Zuzana Plzáková, Mariana GaloviCová, Hans-Joachim Gabius
Pages: 525-531
Published online on: 01 October 2005

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Article

Dealcoholized red wine containing known amounts of resveratrol suppresses atherosclerosis in hypercholesterolemic rabbits without affecting plasma lipid levels

Zhirong Wang, Jiangang Zou, Kejiang Cao, Tze-Chen Hsieh, Yuanzhu Huang, Joseph M. Wu
Pages: 533-540
Published online on: 01 October 2005

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Article

Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinase in uterine endometrial carcinoma and a correlation between expression of matrix metalloproteinase-7 and prognosis

Fumiko Misugi, Toshiyuki Sumi, Eri Okamoto, Hiroyuki Nobeyama, Kanae Hattori, Hiroyuki Yoshida, Yoshinari Matsumoto, Tomoyo Yasui, Ken-ichi Honda, Osamu Ishiko
Pages: 541-546
Published online on: 01 October 2005

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Article

cDNA microarray-based analysis of differentially expressed genes in transgenic brains expressing NSE-controlled APPsw

Seung W. Jee, Jung S. Cho, Jae H. Oh, Sun B. Shim, Dae Y. Hwang, Su H. Lee, Youn S. Song, Seok H. Lee, Yong K. Kim
Pages: 547-552
Published online on: 01 October 2005

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Article

Molecular modeling of O6-methylguanine-DNA methyltransferase mutant proteins encoded by single nucleotide polymorphisms

Sonja M. Schwarzl, Jeremy C. Smith, Bernd Kaina, Thomas Efferth
Pages: 553-557
Published online on: 01 October 2005

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Article

The expression of P53 protein and infection of human papilloma virus in conjunctival and eyelid neoplasms

Yasuyoshi Yabu, Joanna Reszec
Pages: 559-564
Published online on: 01 October 2005

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Article

Inhibition of bacillus Calmette-Guérin-induced nitric oxide in bladder tumor cells may improve BCG treatment

Valeria Alvarez, Catalina Lodillinsky, Sol Umerez, Eduardo Sandes, Ana María Eiján
Pages: 565-571
Published online on: 01 October 2005

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Article

Beta-2 adrenergic receptor genotypes and haplotypes in different ethnic groups

Taylor J. Maxwell, Margaret-Mary Ameyaw, Stuart Pritchard, Nadia Thornton, Gbolahan Folayan, Jessie Githang'a, Anne Indalo, Mohammed Tariq, Abeer Mobarek, David A. Evans, David Ofori-Adjei, Alan R. Templeton, Howard L. McLeod
Pages: 573-580
Published online on: 01 October 2005

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Article

Expression of HOX homeobox genes in the adult human colonic mucosa (and colorectal cancer?)

Giancarlo Freschi, Antonio Taddei, Paolo Bechi, Antonio Faiella, Massimo Gulisano, Clemente Cillo, Giorgio Bucciarelli, Edoardo Boncinelli
Pages: 581-587
Published online on: 01 October 2005

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Article

Chromosomal organization and localization of the novel class IV human histone deacetylase 11 gene

Susanne Voelter-Mahlknecht, Anthony D. Ho, Ulrich Mahlknecht
Pages: 589-598
Published online on: 01 October 2005

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Article

Expression of matrix metalloproteinase 2 and its tissue inhibitor in oral squamous cell carcinoma

Zi-Bin Gao, Yu-Qin Duan, Li Zhang, Da-Wei Chen, Ping-Tian Ding
Pages: 599-603
Published online on: 01 October 2005

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Article

SDevelopment of dextran sulfate sodium-induced colitis is aggravated in mice genetically deficient for complement C5

Yasuyuki Deguchi, Akira Andoh, Osamu Inatomi, Yoshio Araki, Kazunori Hata, Tomoyuki Tsujikawa, Katsuyuki Kitoh, Yoshihide Fujiyama
Pages: 605-608
Published online on: 01 October 2005

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Article

Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus erythematosus

Hiroki Mitoma, Takahiko Horiuchi, Yasutaka Kimoto, Hiroshi Tsukamoto, Ayumi Uchino, Yasuhiro Tamimoto, Yugo Miyagi, Mine Harada
Pages: 609-615
Published online on: 01 October 2005

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Article

Bleomycin stimulates targeted gene repair directed by single-stranded oligodeoxynucleotides in BHK-21 cells

Takayuki Suzuki, Atsushi Murai, Tatsuo Muramatsu
Pages: 615-620
Published online on: 01 October 2005

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Review

Integrative medical therapy: Examination of meditation's therapeutic and global medicinal outcomes via nitric oxide (Review)

George B. Stefano, Tobias Esch
Pages: 621-630
Published online on: 01 October 2005

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Article

Evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease

Makoto Nakamuta, Motoyuki Kohjima, Shusuke Morizono, Kazuhiro Kotoh, Tsuyoshi Yoshimoto, Izuru Miyagi, Munechika Enjoji
Pages: 631-635
Published online on: 01 October 2005

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Article

Overexpression of regucalcin suppresses cell proliferation of cloned normal rat kidney proximal tubular epithelial NRK52E cells

Taeko Nakagawa, Natumi Sawada, Masayoshi Yamaguchi
Pages: 637-643
Published online on: 01 October 2005

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Article

Differential expression of cyclins A, B1, D3 and E in G1 phase of the cell cycle between the synchronized and asynchronously growing MOLT-4 cells

Chunzhao Yu, Junbo Hu, Yongdong Feng, Deding Tao, Jianhong Wu, Jichao Qin, Shuangyou Liu, Manchao Zhang, Gangduo Wang, Xiping Li, Jinshun Zhao, Hong Ding, Eddie Reed, Qingdi Q. Li, Jianping Gong
Pages: 645-651
Published online on: 01 October 2005

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Article

Inhibitory effect of dipeptide alcohol derivatives containing mercapto group on eukaryotic DNA polymerase α

Ikuo Kato, Isoko Kuriyama, Naoki Asano, Kyoko Ikeda, Hiromi Yoshida, Yoshiyuki Mizushina
Pages: 653-659
Published online on: 01 October 2005

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Article

All-trans retinoic acid regulates CXCL16/SR-PSOX expression

Dick Wågsäter, Yuri Shelikine, Allan Sirsjö
Pages: 661-665
Published online on: 01 October 2005

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Article

Effect of processed Scutellaria baicalensis on dextran sulfate sodium-induced colitis in mice

Yeon-A Choi, Ok-Hwa Kang, Hye-Jung Park, Jin Tae, Dae-Ki Kim, Chon Sik Kang, Suck-Chei Choi, Ki-Jung Yun, Suck-Jun Choi, Yong-Ho Nah, Young-Ho Kim, Ki-Hwan Bae, Young-Mi Lee
Pages: 667-672
Published online on: 01 October 2005

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Article

Reduced prepulse inhibition of startle in STAT6-deficient mice

Kazunori Yukawa, Tetsuji Tanaka, Kyoko Owada-Makabe, Yuji Tsubota, Tao Bai, Masanobu Maeda, Kiyoshi Takeda, Shizuo Akira, Hiroyuki Iso
Pages: 673-675
Published online on: 01 October 2005

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Article

Epigallocatechin-3-gallate, a polyphenol component of green tea, suppresses both collagen production and collagenase activity in hepatic stellate cells

Makoto Nakamuta, Nobuhiko Higashi, Motoyuki Kohjima, Marie Fukushima, Satoshi Ohta, Kazuhiro Kotoh, Naoya Kobayashi, Munechika Enjoji
Pages: 677-681
Published online on: 01 October 2005

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Article

Immune deficiency enhances expression of recombinant human antibody in mice after nonviral in vivo gene transfer

Kohji Kitaguchi, Mikako Toda, Masataka Takekoshi, Fumiko Maeda, Tatsuo Muramatsu, Atsushi Murai
Pages: 683-688
Published online on: 01 October 2005

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Article

Albumin regulates Runx2 and α1 (I) collagen mRNA expression in osteoblastic cells: Comparison with insulin-like growth factor-I

Koichi Ishida, Masayoshi Yamaguchi
Pages: 689-694
Published online on: 01 October 2005

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Article

Intracisternal des-acyl ghrelin inhibits food intake and non-nutrient gastric emptying in conscious rats

Chih-Yen Chen, Yee Chao, Full-Young Chang, Eileen Jea Chien, Shou-Dong Lee, Ming-Luen Doong
Pages: 695-699
Published online on: 01 October 2005

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Article

Expression pattern and subcellular localization of five splice isoforms of human PXK

Xianqiong Zou, Guanzhou Qiu, Chunjing Chen, Maoqing Wu, Yuehua Hu, Huarui Zheng, Xin Li, Shaohua Gu, Chaoneng Ji, Yumin Mao
Pages: 701-707
Published online on: 01 October 2005

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Article

XRCC1 polymorphism and lung cancer risk in relation to tobacco smoking

Joachim Schneider, Vera Classen, Ulrike Bernges, Monika Philipp
Pages: 709-716
Published online on: 01 October 2005

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Article

Liver X receptor and retinoic X receptor agonists modulate the expression of genes involved in lipid metabolism in human endothelial cells

G. D. Norata, M. Ongari, P. Uboldi, F. Pellegatta, A. L. Catapano
Pages: 717-722
Published online on: 01 October 2005

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Article

The potential lymphangiogenic effects of hepatocyte growth factor/scatter factor in vitro and in vivo

Wen G. Jiang, Gaynor Davies, Tracey A. Martin, Christian Parr, Gareth Watkins, Robert E. Mansel, Malcolm D. Mason
Pages: 723-728
Published online on: 01 October 2005

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Article

Different effects of bile acids, ursodeoxycholic acid and deoxycholic acid, on cell growth and cell death in human colonic adenocarcinoma cells

Katsuya Shiraki, Takeshi Ito, Kazushi Sugimoto, Hiroyuki Fuke, Tomoko Inoue, Kazumi Miyashita, Takenari Yamanaka, Masahiro Suzuki, Kazuo Nabeshima, Takeshi Nakano, Koujiro Takase
Pages: 729-733
Published online on: 01 October 2005

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Article

The chlorophyllin-induced cell cycle arrest and apoptosis in human breast cancer MCF-7 cells is associated with ERK deactivation and Cyclin D1 depletion

Lawrence C.-M. Chiu, Carrie K.-L. Kong, Vincent E.-C. Ooi
Pages: 735-740
Published online on: 01 October 2005

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Article

Analysis on the mechanism of Helicobacter pylori-induced apoptosis in gastric cancer cell line BGC-823

Yongchang Chen, Ying Wang, Wenrong Xu, Zhijian Zhang
Pages: 741-745
Published online on: 01 October 2005

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Article

GLP-1 signalling and effects on glucose metabolism in myocytes from type 2 diabetic patients

Nieves González, Verónica Sancho, Antonio Martín-Duce, Pilar Tornero-Esteban, Isabel Valverde, Willy J. Malaisse, María L. Villanueva-Pe?acarrillo
Pages: 747-752
Published online on: 01 October 2005

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Article

Failure of interferon-γ and tumor necrosis factor in mediating anemia of chronic disease in a mouse model of protracted septic peritonitis

Thomas E.O. Schubert, Bernd Echtenacher, Ferdinand Hofstädter, Daniela N. Männel
Pages: 753-758
Published online on: 01 October 2005

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Article

The methionine synthase polymorphism c.2756A↷G (D919G) is relevant for disease-free longevity

Michael Linnebank, Klaus Fliessbach, Heike Kolsch, Marcella Rietschel, Ullrich Wullner
Pages: 759-761
Published online on: 01 October 2005

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Article

Reverse transcription-polymerase chain reaction in situ hybridization for SYT-SSX fusion gene transcripts in synovial sarcomas

Shigeto Kawauchi, Toshiro Fukuda, Yasuyo Chochi, Tomoko Kondo, Atsunori Oga, Kohsuke Sasaki
Pages: 763-766
Published online on: 01 October 2005

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Article

Comparative genomics on FGF7, FGF10, FGF22 orthologs, and identification of fgf25

Yuriko Katoh, Masaru Katoh
Pages: 767-770
Published online on: 01 October 2005

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Article

Mutational analysis of the DAL-1/4.1B tumour-suppressor gene locus in meningiomas

Victor Martinez-Glez, M. Josefa Bello, Carmen Franco-Hernandez, Jose M. De Campos, Alberto Isla, Jesus Vaquero, Juan A. Rey
Pages: 771-774
Published online on: 01 October 2005

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Review Open Access

Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Article Open Access

Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Review Open Access

Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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Correction Open Access

[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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