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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2020 Volume 21 Issue 4

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Genetic variations associated with pharmacoresistant epilepsy (Review)

Noemí Cárdenas‑Rodríguez, Liliana Carmona‑Aparicio, Diana L. Pérez‑Lozano, Daniel Ortega‑Cuellar, Saúl Gómez‑Manzo, Iván Ignacio‑Mejía
Pages: 1685-1701
Published online on: 24 February 2020

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Pyrosequencing analysis of IRS1 methylation levels in schizophrenia with tardive dyskinesia

Yanli Li, Kesheng Wang, Ping Zhang, Junchao Huang, Ying Liu, Zhiren Wang, Yongke Lu, Shuping Tan, Fude Yang, Yunlong Tan
Pages: 1702-1708
Published online on: 12 February 2020

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Long non‑coding RNA H19 protects H9c2 cells against hypoxia‑induced injury by activating the PI3K/AKT and ERK/p38 pathways

Linhui Yuan, Leitao Yu, Jing Zhang, Zhidong Zhou, Chang Li, Bin Zhou, Xiaolan Hu, Guohai Xu, Yanhua Tang
Pages: 1709-1716
Published online on: 06 February 2020

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Conditional knockout of pyruvate dehydrogenase in mouse pancreatic β‑cells causes morphological and functional changes

Xiao Wang, Shuchang Lai, Yanshi Ye, Yuanyuan Hu, Daoyan Pan, Xiaochun Bai, Jie Shen
Pages: 1717-1726
Published online on: 20 February 2020

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Circular RNA expression profiling identifies specific circular RNAs in tongue squamous cell carcinoma

Tai Wei, Peng Ye, Guang‑Yan Yu, Zu‑Yan Zhang
Pages: 1727-1738
Published online on: 06 February 2020

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Suppression of CLEC3A inhibits osteosarcoma cell proliferation and promotes their chemosensitivity through the AKT1/mTOR/HIF1α signaling pathway

Chong Ren, Runsang Pan, Lisong Hou, Huaping Wu, Junkang Sun, Wenguang Zhang, Xiaobin Tian, Houping Chen
Pages: 1739-1748
Published online on: 13 February 2020

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Expression of genes involved in neurogenesis, and neuronal precursor cell proliferation and development: Novel pathways of human ovarian granulosa cell differentiation and transdifferentiation capability in vitro

Maciej Brązert, Wiesława Kranc, Piotr Celichowski, Maurycy Jankowski, Hanna Piotrowska‑Kempisty, Leszek Pawelczyk, Małgorzata Bruska, Maciej Zabel, Michał Nowicki, Bartosz Kempisty
Pages: 1749-1760
Published online on: 31 January 2020

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Long non‑coding RNA MALAT1 regulates cholesterol accumulation in ox‑LDL‑induced macrophages via the microRNA‑17‑5p/ABCA1 axis

Limin Liu, Lili Tan, Jian Yao, Lin Yang
Pages: 1761-1770
Published online on: 13 February 2020

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Identification of a novel anti‑heat shock cognate 71 kDa protein antibody in patients with Kawasaki disease

Yabin Zhou, Jiawen Cui, Huimin Hu, Yongqiang Wen, Zhongdong Du, Hongwu Du
Pages: 1771-1778
Published online on: 04 February 2020

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HER4 promotes the progression of colorectal cancer by promoting epithelial‑mesenchymal transition

Xiaojing Jia, Huien Wang, Zhongxin Li, Jing Yan, Yan Guo, Wujie Zhao, Lixia Gao, Bin Wang, Yitao Jia
Pages: 1779-1788
Published online on: 04 February 2020

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Effects of combined treatment with PD‑L1 Ig and CD40L mAb on immune tolerance in the CBA/J x DBA/2 mouse model

Guanfei Li, Lihua Yang, Dan Li, Jinhong Zhang, Ling Du, Libin Xia, Yunhua Liu, Wanqin Hu
Pages: 1789-1798
Published online on: 06 February 2020

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SHARPIN regulates cell proliferation of cutaneous basal cell carcinoma via inactivation of the transcriptional factors GLI2 and c‑JUN

Yao Yang, Yan‑Hua Liang, Yan Zheng, Ling‑Jie Tang, Si‑Tong Zhou, Jing‑Na Zhu
Pages: 1799-1808
Published online on: 07 February 2020

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Ginkgo biloba extract protects diabetic rats against cerebral ischemia‑reperfusion injury by suppressing oxidative stress and upregulating the expression of glutamate transporter 1

Miao Yan, Mei Li, Shuling Gu, Zheng Sun, Tengfei Ma, Xing Ma
Pages: 1809-1818
Published online on: 19 February 2020

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Astragalus polysaccharide inhibits breast cancer cell migration and invasion by regulating epithelial‑mesenchymal transition via the Wnt/β‑catenin signaling pathway

Shuo Yang, Shuqin Sun, Wanqun Xu, Bangxu Yu, Guimei Wang, Haibo Wang
Pages: 1819-1832
Published online on: 12 February 2020

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Adipose‑derived mesenchymal stem cells ameliorate dibutyltin dichloride‑induced chronic pancreatitis by inhibiting the PI3K/AKT/mTOR signaling pathway

Xiangxiang Xu, Huajun Yu, Linxiao Sun, Chenlei Zheng, Yunfeng Shan, Zhenxu Zhou, Cheng Wang, Bicheng Chen
Pages: 1833-1840
Published online on: 21 February 2020

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Single‑strained DNA aptamers mask RhD antigenic epitopes on human RhD+ red blood cells to escape alloanti‑RhD immunological recognition

Yinze Zhang, Hua Xu, Xin Wang, Lin Wang, Ruiqi Liu, Lu Li, Huayou Zhou
Pages: 1841-1848
Published online on: 12 February 2020

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TNF‑α‑mediated epithelial‑to‑mesenchymal transition regulates expression of immune checkpoint molecules in hepatocellular carcinoma

Ritu Shrestha, Kim R. Bridle, Darrell H.G. Crawford, Aparna Jayachandran
Pages: 1849-1860
Published online on: 19 February 2020

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Gli3 is a novel downstream target of miR‑200a with an anti‑fibrotic role for progression of liver fibrosis in vivo and in vitro

Li Li, Jianghua Ran, Lan Li, Gang Chen, Shengning Zhang, Yingjia Wang
Pages: 1861-1871
Published online on: 21 February 2020

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Regulatory mechanism of NOV/CCN3 in the inflammation and apoptosis of lung epithelial alveolar cells upon lipopolysaccharide stimulation

Hai‑Ping Zhu, Hui‑Ya Huang, Deng‑Min Wu, Nian Dong, Li Dong, Cheng‑Shui Chen, Chao‑Lei Chen, Yu‑Guo Chen
Pages: 1872-1880
Published online on: 09 September 2019

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Exosomes from adipose‑derived stem cells promote chondrogenesis and suppress inflammation by upregulating miR‑145 and miR‑221

Chen Zhao, Jin‑Yang Chen, Wen‑Ming Peng, Bo Yuan, Qing Bi, You‑Jia Xu
Pages: 1881-1889
Published online on: 07 February 2020

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Circular RNA hsa_circ_0001380 in peripheral blood as a potential diagnostic biomarker for active pulmonary tuberculosis

Hou‑Long Luo, Ying Peng, Hong Luo, Jun‑Ai Zhang, Gan‑Bin Liu, Huan Xu, Gui‑Xian Huang, Yin‑Fu Sun, Ji Huang, Bi‑Ying Zheng, Ji‑Xin Zhong, Jun‑Fa Xu
Pages: 1890-1896
Published online on: 20 February 2020

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In vitro fertilization and embryo transfer alter human placental function through trophoblasts in early pregnancy

Liang Zhao, Lifang Sun, Xiuli Zheng, Jingfang Liu, Rong Zheng, Rui Yang, Ying Wang
Pages: 1897-1909
Published online on: 31 January 2020

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AIF knockdown induce apoptosis and mitochondrial dysfunction in cochlear spiral ganglion neurons in vitro

Liang Zong, Jiandong Zhao, Wenming Wu, Jialing Wang, Deliang Huang, Mingbo Liu
Pages: 1910-1920
Published online on: 31 January 2020

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Identification of key microRNAs and target genes for the diagnosis of bone nonunion

Yuan Xiong, Faqi Cao, Lang Chen, Chenchen Yan, Wu Zhou, Yanyan Chen, Yori Endo, Xingzhu Leng, Bobin Mi, Guohui Liu
Pages: 1921-1933
Published online on: 21 February 2020

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Glucagon‑like peptide‑1 analogue exendin‑4 modulates serotonin transporter expression in intestinal epithelial cells

Xiufang Cui, Xiaojing Zhao, Ying Wang, Yan Yang, Hongjie Zhang
Pages: 1934-1940
Published online on: 06 February 2020

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TET2 is involved in DNA hydroxymethylation, cell proliferation and inflammatory response in keratinocytes

Xinxin Liu, Xin Wang, Nian Liu, Ke Zhu, Song Zhang, Xiaoru Duan, Yuqiong Huang, Zilin Jin, Himanshu Jaypaul, Yan Wu, Hongxiang Chen
Pages: 1941-1949
Published online on: 18 February 2020

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Article

Upregulation of long non‑coding RNA CCEPR is associated with poor prognosis and contributes to the progression of ovarian cancer through regulating the Wnt/β‑catenin signaling pathway

Zhen Chen, Yingjun Zhu, Xiaodong Fan, Yabo Liu, Qingqing Feng
Pages: 1950-1958
Published online on: 06 February 2020

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Article

Inhibition of heat shock protein 90 attenuates post‑angioplasty intimal hyperplasia

Mohammed M. Kassem, Furqan Muqri, Mary Dacosta, David Bruch, Vivian Gahtan, Kristopher G. Maier
Pages: 1959-1964
Published online on: 20 February 2020

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Article

A novel corona core‑shell nanoparticle for enhanced intracellular drug delivery

Jianwei Jiang, Xiaoming Zhong, Hongyan Zhang, Chunlei Wang
Pages: 1965-1972
Published online on: 24 February 2020

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Article

Association between KCNQ2, TCF4 and RGS18 polymorphisms and silent brain infarction based on whole‑exome sequencing

Jung Oh Kim, Kee Ook Lee, Hyun Woo Kim, Han Sung Park, Jinkwon Kim, Jung Hoon Sung, Doyeun Oh, Ok Joon Kim, Nam Keun Kim
Pages: 1973-1983
Published online on: 05 February 2020

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Retraction Open Access

[Retracted] Differential miRNAomics of the synovial membrane in knee osteoarthritis induced by bilateral anterior cruciate ligament transection in rats

Jiangtao Zhou, Yina Zhao, Guangwen Wu, Bingbing Lin, Zuanfang Li, Xianxiang Liu
Pages: 1984-1984
Published online on: 14 February 2020

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

Maireyanmu Rouzi, Xi Sun, Luguang Sheng, Bilin Xu, Tao Lei, Jun Lu, Jie Gao
Article Number: 101
Published online on: 27 January 2026

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PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
Article Number: 100
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Review Open Access

Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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Review

PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Article Open Access

Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Review Open Access

Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Review Open Access

Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Circular RNAs in intervertebral disc degeneration: Current insights into mechanisms and therapeutic potentials (Review)

Luyan Wang, Ke Yang, Houjun Zhu, Dachuan Wang, Feng Wang, Xianfa Du
Article Number: 111
Published online on: 05 February 2026

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T‑cadherin and its impact on human diseases (Review)

Yan Song, Xinyi Wang, Yunfei Bian
Article Number: 110
Published online on: 05 February 2026

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Review

CD20 monoclonal antibody‑rituximab for the treatment of diffuse alveolar hemorrhage in children (Review)

Xiaobo Zhang, Xiao Wu, Yan Li, Guangmin Nong
Article Number: 109
Published online on: 05 February 2026

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Article Open Access

N6‑methyladenosine reader insulin‑like growth factor 2 mRNA‑binding protein 2 promotes abnormal proliferation of colonic epithelial cells in type 2 diabetes mellitus by regulating midkine

Jieyao Li, Qingsheng Xie, Jihao Xu
Article Number: 108
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin‑induced VEGF expression

Goutam Chakraborty, Shalini Jain, Smita Kale, Remya Raja, Santosh Kumar, Rosalin Mishra, Gopal C. Kundu
Article Number: 107
Published online on: 04 February 2026

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Review Open Access

Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Article Open Access

Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Article Open Access

Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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