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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2012 Volume 5 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Diverse functions of uterine proteoglycans in human reproduction (Review)

Kotaro Kitaya, Yoshihiro Tada, Terumi Hayashi, Sagiri Taguchi, Miyako Funabiki, Yoshitaka Nakamura, Tadahiro Yasuo
Pages: 1375-1381
Published online on: 07 March 2012

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Article Open Access

Diet and effects of diet management on quality of life and symptoms in patients with irritable bowel syndrome

Hege Østgaard, Trygve Hausken, Doris Gundersen, Magdy El-Salhy
Pages: 1382-1390
Published online on: 22 March 2012

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Article Open Access

Knockdown of endothelin A receptor expression inhibits osteosarcoma pulmonary metastasis in an orthotopic xenograft mouse model

Yong Li, Qiande Liao, Kanghua Li, Da Zhong, Xiaojun Weng, Meng Mi
Pages: 1391-1395
Published online on: 21 March 2012

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Article

Improvement of myocardial lipid accumulation and prevention of PGC-1α induction by fenofibrate

Wen-Yan Li, Chun-Xia Yao, Shu-Feng Zhang, Shu-Ling Wang, Tian-Qi Wang, Cheng-Juan Xiong, Yue-Bai Li, Ming-Xi Zang
Pages: 1396-1400
Published online on: 20 March 2012

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Article

Potential synergism of Bim with p53 in mice with Myc‑induced lymphoma in a mouse lymphoma model

Qingjuan Shang, Dianliang Zhang, Chunbao Guo, Qiu Lin, Zhenhua Guo, Chun Deng
Pages: 1401-1408
Published online on: 22 March 2012

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Article

Influence of survivin and Bcl-2 expression on the biological behavior of non-small cell lung cancer

Qin Gao, Sheng Yang, Ming-Qiang Kang
Pages: 1409-1414
Published online on: 19 March 2012

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Article

Radio-sensitization of SHG44 glioma cells by Aidi injection in vitro

Xiao-Ting Xu, Yao Song, Songbing Qin, Li-Li Wang, Ju-Ying Zhou
Pages: 1415-1418
Published online on: 14 March 2012

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Article

Puerarin inhibits caspase-3 expression in osteoblasts of diabetic rats

Junbo Liang, Haixiao Chen, Weibo Pan, Chunli Xu
Pages: 1419-1422
Published online on: 02 April 2012

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Article

Distinct activation of tumor necrosis factor-α and interleukin-6 in the spinal cord after surgical incision in rats

Yan-Ling Zhang, Jun-Mei Xu, Pei Zhou, Xiao-Lin Zhong, Ru-Ping Dai
Pages: 1423-1427
Published online on: 08 March 2012

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Article

Circulating microRNA-122 as a potential biomarker for liver injury

Xianfeng Ding, Jianv Ding, Jing Ning, Fan Yi, Jiankui Chen, Deyao Zhao, Jiaping Zheng, Zicai Liang, Zhiyuan Hu, Quan Du
Pages: 1428-1432
Published online on: 15 March 2012

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Article

High expression and nuclear localization of β-catenin in diffuse large B-cell lymphoma

Xueling Ge, Xiao Lv, Lili Feng, Xiaoqian Liu, Xin Wang
Pages: 1433-1437
Published online on: 13 March 2012

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Article

Expression of STAT3, MMP-1 and TIMP-1 in gastric cancer and correlation with pathological features

Qin-Wei Cai, Jun Li, Xue-Qin Li, Jian-Qiang Wang, Yuan Huang
Pages: 1438-1442
Published online on: 27 March 2012

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Article

Effects of Panax notoginseng flower extract on the TGF-β/Smad signal transduction pathway in heart remodeling of human chymase transgenic mice

Youhua Wang, Peigang Qian, Ping Liu, Li Wei, Min Cao, Li Zhou, Duan Zhou, Zhi-Xiu Lin
Pages: 1443-1448
Published online on: 02 April 2012

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Article

Effect of ascorbic acid and hydrogen peroxide on mouse neuroblastoma cells

Christina M. Hardaway, Ramesh B. Badisa, Karam F.A. Soliman
Pages: 1449-1452
Published online on: 02 April 2012

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Article

Quercetin inhibits human breast cancer cell proliferation and induces apoptosis via Bcl-2 and Bax regulation

Jian Duo, Guo-Guang Ying, Guo-Wen Wang, Li Zhang
Pages: 1453-1456
Published online on: 22 March 2012

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Article

Expression of miR-133 and miR-30 in chronic atrial fibrillation in canines

Hongli Li, Shufeng Li, Bo Yu, Shaowen Liu
Pages: 1457-1460
Published online on: 08 March 2012

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Article

Cyanate attenuates insulin secretion in cultured pancreatic β cells

Eunyoung Ha
Pages: 1461-1464
Published online on: 14 March 2012

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Article

MPTP-induced model of Parkinson's disease in heat shock protein 70.1 knockout mice

Hyun Kyung Park, Ah Rang Cho, Seung Chul Lee, Ju Yeon Ban
Pages: 1465-1468
Published online on: 19 March 2012

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Article

Calcium blockers inhibit cyclosporine A-induced hyperreactivity of vascular smooth muscle cells

Grzegorz Grześk, Michał Wiciński, Bartosz Malinowski, Elżbieta Grześk, Sławomir Manysiak, Grażyna Odrowąż-Sypniewska, Nasser Darvish, Maciej Bierwagen
Pages: 1469-1474
Published online on: 26 March 2012

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Article

Zbtb7 suppresses the expression of CDK2 and E2F4 in liver cancer cells: Implications for the role of Zbtb7 in cell cycle regulation

Xuefeng Yang, Xuyu Zu, Jing Tang, Wei Xiong, Yuan  Zhang, Feng Liu, Yuyang Jiang
Pages: 1475-1480
Published online on: 23 March 2012

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Article

Synergistic anticancer activity of curcumin and bleomycin: An in vitro study using human malignant testicular germ cells

Aysegul Cort, Mujgan Timur, Evrim Ozdemir, Ertan Kucuksayan, Tomris Ozben
Pages: 1481-1486
Published online on: 26 March 2012

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Article

Mast cell chymase promotes cell proliferation and expression of certain cytokines in a dose-dependent manner

Xianglin Dong, Junjie Chen, Yange Zhang, Ying Cen
Pages: 1487-1490
Published online on: 30 March 2012

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Article

Involvement of reactive oxygen species and JNK in increased expression of MCP-1 and infiltration of inflammatory cells in pressure-overloaded rat hearts

Fujun Shang, Jiepin Wang, Xiongtao Liu, Jun Li, Qiangsun Zheng, Yusheng Xue, Lianyou Zhao
Pages: 1491-1496
Published online on: 30 March 2012

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Article

Effect of hydrogen sulfide on restenosis of peripheral arteries after angioplasty

Bingbing Ma, Gangzhu Liang, Fuxian Zhang, Yizhi Chen, Huan Zhang
Pages: 1497-1502
Published online on: 02 April 2012

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Article

Antitumor activity of Chidamide in hepatocellular carcinoma cell lines

Haijuan Wang, Yi Guo, Ming Fu, Xiao Liang, Xueyan Zhang, Renzhi Wang, Chen Lin, Haili Qian
Pages: 1503-1508
Published online on: 05 April 2012

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Article

Dexamethasone inhibits TGF-β2-induced migration of human lens epithelial cells: Implications for posterior capsule opacification prevention

Jin Yao, Wen Yang, Yuan Liu, Yan-Xi Sun, Qin Jiang
Pages: 1509-1513
Published online on: 08 March 2012

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Article

Circulating miR-17-5p and miR-20a: Molecular markers for gastric cancer

Mei Wang, Hongbing Gu, Sheng Wang, Hui Qian, Wei Zhu, Ling Zhang, Chonghui Zhao, Yang Tao, Wenrong Xu
Pages: 1514-1520
Published online on: 08 March 2012

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Article

Study of a family in the province of Matera presenting with glucose-6-phosphate dehydrogenase deficiency and Gilbert's syndrome

Domenico Dell'Edera, Annunziata Anna Epifania, Andrea Tinelli, Manuela Leo, Antonio Novelli, Antonio Di Trani, Giuseppe Barrano, Marta Bertoli, Eleonora Mazzone, Michele Benedetto, Damian Simona, Antonio Malvasi
Pages: 1521-1525
Published online on: 08 March 2012

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Article

Altered expression of mitochondrial cytochrome c oxidase I and NADH dehydrogenase 4 transcripts associated with gastric tumorigenesis and tumor dedifferentiation

Jie-Tao Ma, Cheng-Bo Han, Yang Zhou, Jian-Zhu Zhao, Wei Jing, Hua-Wei Zou
Pages: 1526-1530
Published online on: 09 March 2012

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Article

Serum biomarker screening for the diagnosis of early gastric cancer using SELDI-TOF-MS

Ping Li, Dianliang Zhang, Chunbao Guo
Pages: 1531-1535
Published online on: 13 March 2012

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Article

Loss of imprinting of IGF2 correlates with hypomethylation of the H19 differentially methylated region in the tumor tissue of colorectal cancer patients

Fuliang Tian, Zhipeng Tang, Guoqi Song, Yuqin Pan, Bangshun He, Qian Bao, Shukui Wang
Pages: 1536-1540
Published online on: 13 March 2012

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Article

The orphan nuclear receptor Nur77 regulates hepatic cholesterol metabolism through the suppression of LDLR and HMGCR expression

Peng Zhang, Yanwei Hu, Junyao Yang, Lei Zheng, Qian Wang
Pages: 1541-1547
Published online on: 28 March 2012

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Article

Renal protective effect of Rosa laevigata Michx. by the inhibition of oxidative stress in streptozotocin-induced diabetic rats

Yujuan Zhou, Qianjin Liao, Yuping Luo, Zhenqi Qing, Qiuju Zhang, Guoping He
Pages: 1548-1554
Published online on: 02 April 2012

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

Maireyanmu Rouzi, Xi Sun, Luguang Sheng, Bilin Xu, Tao Lei, Jun Lu, Jie Gao
Article Number: 101
Published online on: 27 January 2026

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Article Open Access

PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
Article Number: 100
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Review Open Access

Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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Article Open Access

HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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Review

PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Review Open Access

Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Article Open Access

Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Review Open Access

Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Article Open Access

Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Review Open Access

Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Article Open Access

Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Article Open Access

Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Circular RNAs in intervertebral disc degeneration: Current insights into mechanisms and therapeutic potentials (Review)

Luyan Wang, Ke Yang, Houjun Zhu, Dachuan Wang, Feng Wang, Xianfa Du
Article Number: 111
Published online on: 05 February 2026

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T‑cadherin and its impact on human diseases (Review)

Yan Song, Xinyi Wang, Yunfei Bian
Article Number: 110
Published online on: 05 February 2026

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Review

CD20 monoclonal antibody‑rituximab for the treatment of diffuse alveolar hemorrhage in children (Review)

Xiaobo Zhang, Xiao Wu, Yan Li, Guangmin Nong
Article Number: 109
Published online on: 05 February 2026

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N6‑methyladenosine reader insulin‑like growth factor 2 mRNA‑binding protein 2 promotes abnormal proliferation of colonic epithelial cells in type 2 diabetes mellitus by regulating midkine

Jieyao Li, Qingsheng Xie, Jihao Xu
Article Number: 108
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin‑induced VEGF expression

Goutam Chakraborty, Shalini Jain, Smita Kale, Remya Raja, Santosh Kumar, Rosalin Mishra, Gopal C. Kundu
Article Number: 107
Published online on: 04 February 2026

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Review Open Access

Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Article Open Access

Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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