Open Access

Progress in modeling avian hyperuricemia and gout (Review)

  • Authors:
    • Linlin Wang
    • Jialin Li
    • Bo Wang
    • Xianglin Yin
    • Jinfeng Wei
    • Hongbin Qiu
  • View Affiliations

  • Published online on: October 14, 2024     https://doi.org/10.3892/br.2024.1879
  • Article Number: 1
  • Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Human organ tissue is vulnerable to hyperuricemia (HUA), which negatively impacts quality of life, particularly when it progresses to gout. Chicken uric acid formation and metabolism are similar to human uric acid metabolism; therefore, theoretically, the genesis and progression of human HUA and gout may be similar to those of poultry models. The present review explored HUA and gout and the progress of poultry‑induced HUA and gout models. The present study reviewed procedures of modelling chicken gout and HUA and the detection indices and current concerns regarding these models. Notably, In the production of poultry hyperuricemia model, the combined method of water and food induction has a higher success rate and stability. Compared with mice induced HUA and gout models, poultry induced HUA and gout models had less kidney damage, and the models were stable and long‑lasting.
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January-2025
Volume 22 Issue 1

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Copy and paste a formatted citation
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Spandidos Publications style
Wang L, Li J, Wang B, Yin X, Wei J and Qiu H: Progress in modeling avian hyperuricemia and gout (Review). Biomed Rep 22: 1, 2025.
APA
Wang, L., Li, J., Wang, B., Yin, X., Wei, J., & Qiu, H. (2025). Progress in modeling avian hyperuricemia and gout (Review). Biomedical Reports, 22, 1. https://doi.org/10.3892/br.2024.1879
MLA
Wang, L., Li, J., Wang, B., Yin, X., Wei, J., Qiu, H."Progress in modeling avian hyperuricemia and gout (Review)". Biomedical Reports 22.1 (2025): 1.
Chicago
Wang, L., Li, J., Wang, B., Yin, X., Wei, J., Qiu, H."Progress in modeling avian hyperuricemia and gout (Review)". Biomedical Reports 22, no. 1 (2025): 1. https://doi.org/10.3892/br.2024.1879