Progress in modeling avian hyperuricemia and gout (Review)
- Authors:
- Linlin Wang
- Jialin Li
- Bo Wang
- Xianglin Yin
- Jinfeng Wei
- Hongbin Qiu
-
Affiliations: Jiamusi University, Jiamusi, Heilongjiang 154007, P.R. China, Jiamusi University, Jiamusi, Heilongjiang 154007, P.R. China - Published online on: October 14, 2024 https://doi.org/10.3892/br.2024.1879
- Article Number: 1
-
Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
This article is mentioned in:
Abstract
Huang J, Yang T, Wang Y and Zhang B: Progress and thinking on the treatment of gout disease at home and abroad. World Chin Med. 16:1–7. 2021.(In Chinese). | |
No authors listed. Dietary guide for hyperuricemia and gout patients (WS/T 560-2017). Biomed Environ Sci. 36:897–898. 2023.PubMed/NCBI View Article : Google Scholar | |
Sun LM, Xia XL and Ma HP: Research progress on the relationship between hyperuricemia and hypertension and cardiovascular diseases. Shanxi Med J. 53:286–289. 2024. | |
Jiang J, Zhang T, Liu Y, Chang Q, Zhao Y, Guo C and Xia Y: Prevalence of diabetes in patients with hyperuricemia and gout:A systematic review and meta-analysis. Curr Diab Rep. 23:103–117. 2023.PubMed/NCBI View Article : Google Scholar | |
Zhou H and Liang W: Chronic kidney disease and hyperuricemia. J Clin Internal Med. 40:374–378. 2023.(In Chinese). | |
Wang X, Hou Y, Wang X, Li Z, Wang X, Li H, Shang L, Zhou J and Zhang Y, Ren M and Zhang Y: Relationship between serum uric acid levels and different types of atrial fibrillation:An updated meta-analysis. Nutr Metab Cardiovasc Dis. 31:2756–2765. 2021.PubMed/NCBI View Article : Google Scholar | |
She D, Wang Y, Liu J, Luo N, Feng S, Li Y, Xu J, Xie S, Zhu Y, Xue Y and Zhang Z: Changes in the prevalence of hyperuricemia in clients of health examination in Eastern China, 2009 to 2019. BMC Endocr Disord. 22(202)2022.PubMed/NCBI View Article : Google Scholar | |
Tang YS, Liu H and Liu BC: Reflections on the basis of changes: the epidemiological data of hyperuricemia. Drugs and Clinic. 12:8–13. 2015.(In Chinese). | |
Liu C, Sun M and Liao M: A review of emerging goose astrovirus causing gout. Biomed Res Int. 2022(1635373)2022.PubMed/NCBI View Article : Google Scholar | |
Bulbule NR, Kapgate SS and Chawak MM: Infectious causes of gout in chickens. Adv Anim Vet Sci. 2:255–260. 2014. | |
Zhou YZ and Wu SK: Comprehensive diagnosis and treatment of a case of gout in quails. Anim Husbandry Poult Industry. 6:89–90. 2009.(In Chinese). | |
Herbert JD, Coulson JO and Coulson TD: Quantification of tissue uric acid levels in a Harris's hawk with visceral gout. Avian Dis. 55:513–515. 2011.PubMed/NCBI View Article : Google Scholar | |
Wang ZG: Diagnosis and treatment of avian gout. Jilin Anim Husbandry Vet Med. 44:89–90. 2023.(In Chinese). | |
Xing LJ: Diagnosis and treatment of duck gout. Poult Farming Poult Dis Control. 12:43–44. 2010.(In Chinese). | |
Guo HW: Etiological analysis and diagnosis and treatment of goose gout. Anim Sci Technology Information. 1:174–176. 2023.(In Chinese). | |
Liu B: The diagnosis and treatment of peacock gout. Anim Husbandry Vet Sci Tech Inf. 8:207–209. 2023.(In Chinese). | |
Chu B: Diagnosis and treatment of gout in Turkey. Chin J Poult Ind. 8(29)2003.(In Chinese). | |
McFarland DC and Coon CN: Purine metabolism studies in the high and low uric acid containing lines of chickens: De novo uric acid synthesis and xanthine dehydrogenase activities. Poult Sci. 59:2250–2255. 1980.PubMed/NCBI View Article : Google Scholar | |
Roman YM: The role of uric acid in human health: Insights from the uricase gene. J Pers Med. 13(1409)2023.PubMed/NCBI View Article : Google Scholar | |
McFarland DC and Coon CN: Purine metabolism in high- and low-uric acid lines of chickens: hypoxanthine/guanine phosphoribosyltransferase activities. Proc Soc Exp Biol Med. 173:41–47. 1983.PubMed/NCBI View Article : Google Scholar | |
Guo X, Huang K and Tang J: Clinicopathology of gout in growing layers induced by high calcium and high protein diets. Br Poult Sci. 46:641–646. 2005.PubMed/NCBI View Article : Google Scholar | |
Wu H, Wang Y, Ren Z, Li Y, Huang J, Lin Z and Zhang B: Overnutrition-induced gout: An immune response to NLRP3 inflammasome dysregulation by XOD activity increased in quail. Front Immunol. 13(1074867)2022.PubMed/NCBI View Article : Google Scholar | |
Austic RE and Cole RK: Impaired renal clearance of uric acid in chickens having hyperuricemia and articular gout. Am J Physiol. 223:525–530. 1972.PubMed/NCBI View Article : Google Scholar | |
Cole RK and Austic RE: Hereditary uricemia and articular gout in chickens. Poult Sci. 59:951–960. 1980.PubMed/NCBI View Article : Google Scholar | |
Lakshmi Namratha M, Kumar YR and Lakshman M: Pathology of visceral gout in layer chicken. Int J Recent Sci Res. 10:35546–35548. 2019.https://www.researchgate.net/publication/338898873. | |
Rahimi M, Minoosh Z and Haghighi S: Visceral urate deposition in a little bittern (Ixobrychus minutus). Vet Res Forum. 6:177–180. 2015.PubMed/NCBI | |
Lin ZJ, Zhang B, Li LY and Zhu CS: Study on oxidative stress condition of hyperuricemia quail model. J Clin Exp Med. 14:1665–1668. 2015.(In Chinese). | |
Wang Y, Lin ZJ, Huang J, Chu MZ, Ding XL, Li WJ, Mao QY and Zhang B: An integrated study of Shenling Baizhu San against hyperuricemia: Efficacy evaluation, core target identification and active component discovery. J Ethnopharmacol. 295(115450)2022.PubMed/NCBI View Article : Google Scholar | |
Wu H, Wang Y, Huang J, Li Y, Lin Z and Zhang B: Rutin ameliorates gout via reducing XOD activity,inhibiting ROS production and NLRP3 inflammasome activation in quail. Biomed Pharmacother. 158(114175)2023.PubMed/NCBI View Article : Google Scholar | |
Li F, Zhang GW, Li XH, et al: Comparison of the uric acid-lowering effect of 3,4-dihydroxy-5-nitrobenzaldehyde on mouse and quail hyperuricemia models. J Xi'an Jiaotong Univ (Med Sci). 43:827–832. 2022.(In Chinese). | |
Kuang HY, Cheng TP, Hu JB, Cao Z, Kou W and Rong J: Constructing method of chicken model with persistent hyperuricemia model. Sichuan J Zool. 4:554–558. 2008.(In Chinese). | |
Hevia P and Clifford AJ: Protein intake, uric acid metabolism and protein efficiency ratio in growing chicks. J Nutr. 107:959–964. 1977.PubMed/NCBI View Article : Google Scholar | |
Li MM, Ding XD, Rong XL, Fang TY, Qian SF, He MC, Li Y, Li JC and Wu JJ: Clinical pathological study of gosling gout induced by high protein diet. J South China Agr Univ. 40:46–52. 2019.(In Chinese). | |
Wang Z, Hu ZH, Li ST, Gui X, Feng S, Li Y, Wang X, Li J and Wu J: Study on serum metabonomics of goslings with hyperuricemia induced by high protein diet. J Nanjing Agr Univ. 44:1169–1176. 2021.(In Chinese). | |
Hong F, Zheng A, Xu P, Wang J, Xue T, Dai S, Pan S, Guo Y, Xie X, Li L, et al: High-protein diet induces hyperuricemia in a new animal model for studying human gout. Int J Mol Sci. 21(2147)2020.PubMed/NCBI View Article : Google Scholar | |
Liu W: The expression of VIP in immune organs and the investigation of hemorheology of hyperuricemia model chickens. Anhui Agr Univ, 2010 (In Chinese). | |
Wang SZ, Li FB, Wu CJ, Liu W, Yang J, Luo YX, Liu XB and Wu JJ: Serology test on experimental hyperuricemia chicken. Anim Husbandry Feed Sci. 31:10–12. 2010.(In Chinese). | |
Xi Y, Huang Y, Li Y, Yan J and Shi Z: Fermented feed supplement relieves caecal microbiota dysbiosis and kidney injury caused by high-protein diet in the development of gosling gout. Animals (Basel). 10(2139)2020.PubMed/NCBI View Article : Google Scholar | |
Lumeij JT, Sprang EP and Redig PT: Further studies on allopurinol-induced hyperuricaemia and visceral gout in red-tailed hawks (Buteo jamaicensis). Avian Pathol. 27:390–393. 1998.PubMed/NCBI View Article : Google Scholar | |
Lumeij JT and Remple JD: Plasma urea,creatinine and uric acid concentrations in relation to feeding in peregrine falcons (Falco peregrinus). Avian Pathol. 20:79–83. 1991.PubMed/NCBI View Article : Google Scholar | |
Bollman JL and Schlotthauer CF: Experimental gout in turkeys. Am J Digest Dis. 3:483–488. 1936. | |
Li D, Zhang M, Teng Zhu La A, Lyu Z, Li X, Feng Y, Liu D, Guo Y and Hu Y: Quercetin-enriched Lactobacillus aviarius alleviates hyperuricemia by hydrolase-mediated degradation of purine nucleosides. Pharmacol Res. 196(106928)2023.PubMed/NCBI View Article : Google Scholar | |
Liu RH, Shi W, Zhang YX, Zhuo M and Li XH: Selective inhibition of adenylyl cyclase subtype 1 reduces inflammatory pain in chicken of gouty arthritis. Mol Pain. 17(17448069211047863)2021.PubMed/NCBI View Article : Google Scholar | |
Li XM, Deng MX, Li QY, Jia RY and Wang J: Experimental study on clinical pathology deposition of urate in chickens. Chin J Vet Sci. 18:50–52. 1998. | |
Ren YY: Establishment of an experimental chicken hyperuricemia model. J Huaibei Professional Tech Coll. 12:133–135. 2013.(In Chinese). | |
Guo XQ, Huang KH, Chen F and Luo JB: Renal injury and apoptosis in growers with gout induced by high dietary calcium. Chin J Vet Sci. 28:1461–1463, 1479. 2008.(In Chinese). | |
Song N, Wang M, Zhong G, Zhu K, Chen P, Zhang N, Liu X and Zhang W: Bacteroides xylanisolvens possesses a potent anti-hyperuricemia effect in goslings fed on a high-protein diet. Front Microbiol. 14(1173856)2023.PubMed/NCBI View Article : Google Scholar | |
Xi YM, Yan JS, Ying SJ, et al: Effects of high protein and high calcium diet on visceral gout, renal function and intestinal microflora in goslings. Chin J of Anim Nutr. 31:612–621. 2019.(In Chinese). | |
Zheng L, Bai Y, Wan Y, Liu F, Xie Y, He J and Guo P: Ameliorative action of "daitongxiao" against hyperuricemia includes the "uric acid transporter group". Front Pharmacol. 15(1300131)2024.PubMed/NCBI View Article : Google Scholar | |
Lin ZJ, Li F and Zhang B: Advances in research on hyperuricemia in avians. Acta Lab Anim Sci Sin. 25:572–576. 2017. | |
Li CD, Gao L, You GS, et al: Effect of ultrafine powder of Mazhu powder on quail hyperuricemia. Hebei Med J. 31:490–491. 2009.(In Chinese). DOI: 10.3969/j.issn.1002-7386.2009.04.054. | |
Ding X, Peng C, Li S, Li M, Li X, Wang Z, Li Y, Wang X, Li J and Wu J: Chicken serum uric acid level is regulated by glucose transporter 9. Anim Biosci. 34:670–679. 2021.PubMed/NCBI View Article : Google Scholar | |
Zhao ZS, Kong T and Zhou BH: Establishment of chicken hyperuircemia model and its inhibition by allopurine. Chin J Vet Sci. 34:1345–1348. 2014.(In Chinese). | |
Huanga KH: Clinicopathology of Gout in growing layers induced by high calcium and high protein diets. Proceedings of the International Symposium on Metabolic Diseases in Poultry Nutrition, 2006. | |
Fu Y, Chen YS, Xia DY, Luo XD, Luo HT, Pan J, Ma WQ, Li JZ, Mo QY, Tu Q, et al: Lactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model. NPJ Biofilms Microbiomes. 10(25)2024.PubMed/NCBI View Article : Google Scholar | |
Rexhepi A, Brown C, Sherifi K and Behluli B: Visceral gout (Uricosis) and urolithiasis caused by dehydration in laying hen farm, necropsy and histopathology findings. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 21:291–294. 2015. | |
Chu MZ, Lin ZJ, Zhang B, et al: Induction of visceral gout model in quail. Chin Pharmacol Bull. 36:879–883. 2020.(In Chinese). DOI: 10.3969/j.issn.1001-1978.2020.06.026. | |
Yan M, Zheng X, Lin Y, Zheng X, Xi K, Gao Y, Wang H, Li Y and Liu C: Effects of Smilax China L. extracts on Hyperuricemia chicken model via inhibiting xanthine oxidase activity. Poult Sci. 103(103887)2024.PubMed/NCBI View Article : Google Scholar | |
Wu J, Aga L, Tang L, Li H, Wang N, Yang L, Zhang N and Wang X and Wang X: Lacticaseibacillus paracasei JS-3 isolated from "Jiangshui" ameliorates hyperuricemia by regulating gut microbiota and iTS metabolism. Foods. 13(1371)2024.PubMed/NCBI View Article : Google Scholar | |
Qi XY, Xiang LL, Xiong H, Li TL, Zhou B, Guo YX and Lu XL: A dose-effect relationship study of gouty arthritis chicken model built by high-protein diet. J Trad Chin Orthop Trauma. 27:1–6. 2015.(In Chinese). | |
Wang CY and He JH: Relationship between Hyperuricemia and hypertension, obesity, hyperlipidemia and diabetes. J Applied Med. 5:819–821. 2010.(In Chinese). | |
Lin ZJ, Zhang B, Huang SN and Li LY: Advances in research of animal models of hyperuricemia combined with abdominal obesity. Acta Lab Anim Sci Sin. 4:81–85. 2014.(In Chinese). | |
Lin Z, Zhang B, Liu X, Jin R and Zhu W: Effects of chicory inulin on serum metabolites of uric acid, lipids, glucose, and abdominal fat deposition in quails induced by purine-rich diets. J Med Food. 17:1214–1221. 2014.PubMed/NCBI View Article : Google Scholar | |
Lin ZJ, Zhang B, Liu XQ and Yang HL: Abdominal fat accumulation with hyperuricemia and hypercholesterolemia quail model induced by high fat diet. Chin Med Sci J. 24:191–194. 2009.PubMed/NCBI View Article : Google Scholar | |
Ma L, Zeng GR, Zhang MH, Deng Q, Zhang D, Pan SQ, Jiang DJ and Wang XQ: Hunan Center for Drug Safety Evaluation, Institute of Medicinal Plant Beijing Union Medical College. Lipid metabolism study quail high uric acid hematic disease animal model. Chin J Comp Med. 11:17–20+5. 2015. | |
Zhang Y, Ma LM and Wu GZ: High fat high purine diet combined oteracil potassium induced quail glucose and lipid metabolic disorders and complications. Chin J Comp Med. 1:58–64. 2016.(In Chinese). | |
Chen JK and Fan GX: Pathological study on gout induced by high calcium and low phosphorus diet in chickens. Acta Veterinaria et Zootechnica Sinica. 1:80–86. 1992.(In Chinese). | |
Jian GL, Qing YF and Zhang QB: Research status and progress of animal models of gout. Medical Review. 27:2397–2401. 2021. | |
Pegram RA and Wyatt RD: Avian gout caused by oosporein,a mycotoxin produced by Chaetomium trilaterale. Poult Sci. 60:2429–2440. 1981.PubMed/NCBI View Article : Google Scholar : (In Chinese). | |
Timurkaan N, Öngör H, Kalender H, Karabulut B, Çöven F, Çevik A, Eröksüz H and Çetinkaya B: Pathological and molecular findings of visceral gout caused by Israel variant 2 (IS/1494/06) genotype of infectious bronchitis virus in chickens. Ankara Univ Vet Fak Derg. 70:149–156. 2023. | |
Li L, Sun M, Zhang Y and Liao M: A review of the emerging poultry visceral gout disease linked to avian Astrovirus infection. Int J Mol Sci. 23(10429)2022.PubMed/NCBI View Article : Google Scholar | |
Xiang Y, Tang Z, Li Ll, et al: Progress in the study of a new type of goose astrovirus causing goslings gout. Guangdong Anim Husbandry Vet Sci Tech. 49:1–7. 2024.(In Chinese). | |
Yin D, Tian J, Yang J, Tang Y and Diao Y: Pathogenicity of novel goose-origin astrovirus causing gout in goslings. BMC Vet Res. 17(40)2021.PubMed/NCBI View Article : Google Scholar | |
Ejaz S, Kim BS and Lim CW: Gout induced by intoxication of sodium bicarbonate in Korean native broilers. Drug Chem Toxicol. 28:245–261. 2005.PubMed/NCBI View Article : Google Scholar | |
Ali R, Kamil SA, Mir MS, et al: Disease modifying activity of methanolic extract of Colchicum luteum against experimental gout in broiler chicken. Indian Journal of Natural Products and Resources (IJNPR)[Formerly Natural Product Radiance (NPR)]. 13:223–229. 2022.DOI: 10.56042/ijnpr.v13i2.41191. | |
Patel NJ, Joshi BP, Prajapati KS and Patil VM: Pathomorphological changes of aceclofenac toxicity in layer chicks. Veterinary World. 7:90–94. 2014. | |
Sandhyarani K, Madhuri D, Jeevanalatha M and Dhanalakshmi K: Histopathological changes in liver and heart of diclofenac induced visceral gout in broilers and its amelioration with ayurvet product. Pharma Innovat. 8:250–255. 2019. | |
Jiao HJ: Establishment and application of a rapid diagnostic method for chicken gout strip[D]. Hebei Normal Univ Sci Tech, 2020 (In Chinese). | |
Qiu GN, Li ZD and Miao MS: Analysis of application characteristics of hyperuricemia animal model based on data mining. Trad Chin Drug Res & Clin Pharmacol. 34:222–227. 2023.(In Chinese). | |
Cao J, Bu Y, Hao H, Liu Q, Wang T, Liu Y and Yi H: Effect and potential mechanism of Lactobacillus plantarum Q7 on hyperuricemia in vitro and in vivo. Front Nutr. 9(954545)2022.PubMed/NCBI View Article : Google Scholar | |
Cao J, Liu Q, Hao H, Bu Y, Tian X, Wang T and Yi H: Lactobacillus paracasei X11 ameliorates hyperuricemia and modulates gut microbiota in mice. Front Immunol. 13(940228)2022.PubMed/NCBI View Article : Google Scholar | |
Kang L, Miao MS, Liu HJ and Li N: Analysis of animal model based on clinical symptoms of gout. Zhongguo Zhong Yao Za Zhi. 43:4547–4552. 2018.PubMed/NCBI View Article : Google Scholar : (In Chinese). | |
Yue YS, Zhang W, Xie YF, Qin XM and Du GH: Research progress on experimental animal models of hyperuricemia. Chin Pharmacol Bull. 39:201–206. 2023.(In Chinese). | |
Liang H, Deng P, Ma YF, Wu Y, Ma ZH, Zhang W, Wu JD, Qi YZ, Pan XY and Huang FS: , et al: Advances in experimental and clinical research of the gouty arthritis treatment with Traditional Chinese Medicine. Evid Based Complement Alternat Med. 2021(8698232)2021.PubMed/NCBI View Article : Google Scholar | |
Tan WB and Li J: Evaluation of different modeling methods to establish hyperuricemia animal models. Acad J Chin PLA Med Sch. 45:12–17. 2024. | |
Meng J, Tian JZ, Wang LM, Zhao Y, Li CY, Yi Y, Zhang YS, Han JY, Pan C, Liu SY, et al: Adequate Animal Models of Hyperuricemia for Traditional Chinese Medicine Screening. Chin J Exp Trad Med Formulae. 27:46–56. 2021.(In Chinese). | |
Bian M, Wang J, Wang Y, Nie A, Zhu C, Sun Z, Zhou Z and Zhang B: Chicory ameliorates hyperuricemia via modulating gut microbiota and alleviating LPS/TLR4 axis in quail. Biomed Pharmacother. 131(110719)2020.PubMed/NCBI View Article : Google Scholar | |
Wang Z, Li Y, Liao W, Huang J, Liu Y, Li Z and Tang J: Gut microbiota remodeling: A promising therapeutic strategy to confront hyperuricemia and gout. Front Cell Infect Microbiol. 12(935723)2022.PubMed/NCBI View Article : Google Scholar | |
Lin S, Zhang T, Zhu L, Pang K, Lu S, Liao X, Ying S, Zhu L, Xu X, Wu J and Wang X: Characteristic dysbiosis in gout and the impact of a uric acid-lowering treatment, febuxostat on the gut microbiota. J Genet Genomics. 48:781–791. 2021.PubMed/NCBI View Article : Google Scholar | |
Zhang QZ, Zhang JR, Li X, Yin JL, Jin LM, Xun ZR, Xue H, Yang WQ, Zhang H, Qu J, et al: Fangyukangsuan granules ameliorate hyperuricemia and modulate gut microbiota in rats. Front Immunol. 15(1362642)2024.PubMed/NCBI View Article : Google Scholar | |
Guo Z, Zhang J, Wang Z, Ang KY, Huang S, Hou Q, Su X, Qiao J, Zheng Y, Wang L, et al: Intestinal microbiota distinguish gout patients from healthy humans. Sci Rep. 6(20602)2016.PubMed/NCBI View Article : Google Scholar | |
Huang SN, Lin ZJ, Zhang B, Geng D, Niu H, Zhu C, Wang X and Sun B: Effects of chicory on gut microflora of hyperuricemia quail. Trad Chin Drug Res Clin Pharm. 26:447–451. 2015.(In Chinese). | |
Qin DE, Liang W, Yu Y, Whelan EC, Yuan X, Wang ZL, Wu XW, Cao ZR, Hua SY, Yin L, et al: Modified Simiaowan prevents and treats gouty arthritis via the Nrf2/NLRP3 inflammasome signaling pathway. J Ethnopharmacol. 318(Pt A)(116906)2024.PubMed/NCBI View Article : Google Scholar | |
Xu MX, Wang M and Yang WW: Gold-quercetin nanoparticles prevent metabolic endotoxemia-induced kidney injury by regulating TLR4/NF-κB signaling and Nrf2 pathway in high fat diet fed mice. Int J Nanomedicine. 12:327–345. 2017.PubMed/NCBI View Article : Google Scholar | |
Xi Y, Yan J, Li M, Ying S and Shi Z: Gut microbiota dysbiosis increases the risk of visceral gout in goslings through translocation of gut-derived lipopolysaccharide. Poult Sci. 98:5361–5373. 2019.PubMed/NCBI View Article : Google Scholar | |
Si K and Wang YG: Current situation and prospect of diagnosis and treatment of gout and hyperuricemia with integrated traditional Chinese and western medicine. Chin J Clin Health. 26:606–609. 2023.(In Chinese). | |
Zhou Z and Yu D: Research progress on mechanism of gouty arthritis treated by traditional Chinese medicine. Chinese medicine information. 41:71–79. 2024.(In Chinese). | |
Lin ZJ, Liu XQ, Zhang B, Xue CM, Liu XL, Wu LL and Zhu WJ: Study on syndrome categorization of hyperuricemia quail model base on quantitative analysis. Chi J Tradit Chin Med Pharm. 26:1072–1076. 2011.(In Chinese). | |
Zhou ZZ, Xu L and Gao JD: Research progress of Hyperuricemia animal model. Med Rev. 26:1462–1466. 2020.(In Chinese). | |
Gao Y, Yu Y, Qin W, Fan N, Qi Y, Chen H and Duan W: Uricase-deficient rats with similarly stable serum uric acid to human's are sensitive model animals for studying hyperuricemia. PLoS One. 17(e0264696)2022.PubMed/NCBI View Article : Google Scholar | |
Wu X, Wakamiya M, Vaishnav S, Geske R, Montgomery C Jr, Jones P, Bradley A and Caskey CT: Hyperuricemia and urate nephropathy in urate oxidase-deficient mice. Proc Natl Acad Sci U S A. 91:742–746. 1994.PubMed/NCBI View Article : Google Scholar | |
Zhu Y, Peng X and Ling G: An update on the animal models in hyperuricaemia research. Clin Exp Rheumatol. 35:860–864. 2017.PubMed/NCBI | |
Lu J, Dalbeth N, Yin H, Li C, Merriman TR and Wei WH: Mouse models for human hyperuricaemia: A critical review. Nat Rev Rheumatol. 15:413–426. 2019.PubMed/NCBI View Article : Google Scholar | |
Xu Y, Chen P, Sun L, Yan Zou, Lixing Zhang, Wanghai Tang, Tingji Zhang, Huo J and Zhou J: Effect and mechanism of Yiqing decoction on hyperuricemia rats. Cell Mol Biol (Noisy-le-grand). 70:217–224. 2024.PubMed/NCBI View Article : Google Scholar | |
Zhou H, Yang J, Yuan X, Song X, Zhang X, Cao T and Zhang J: Hyperuricemia research progress in model construction and traditional Chinese medicine interventions. Front Pharmacol. 15(1294755)2024.PubMed/NCBI View Article : Google Scholar | |
Yu SY and Miao MS: Studies on the screening methods and mechanisms of anti-gout drugs. Chin J Trad Chin Med. 28:1875–1878. 2013.(In Chinese). | |
Wang L, Tao Y, Wang X, Gan Y, Zeng Y, Li S and Zhu Q: Aqueous extract of Phellinus igniarius ameliorates hyperuricemia and renal injury in adenine/potassium oxonate-treated mice. Biomed Pharmacother. 177(116859)2024.PubMed/NCBI View Article : Google Scholar | |
Wang M, Zhao J, Zhang N and Chen J: Astilbin improves potassium oxonate-induced hyperuricemia and kidney injury through regulating oxidative stress and inflammation response in mice. Biomed Pharmacother. 83:975–988. 2016.PubMed/NCBI View Article : Google Scholar | |
Lu J, Hou X, Yuan X, Cui L, Liu Z, Li X, Ma L, Cheng X, Xin Y, Wang C, et al: Knockout of the urate oxidase gene provides a stable mouse model of hyperuricemia associated with metabolic disorders. Kidney Int. 93:69–80. 2018.PubMed/NCBI View Article : Google Scholar | |
Aynur A, Buviayxem N, Adila A, et al: Dynamic comparison of hyperuricemia animal model in male and female rats. Advances in cardiovascular disease. 44:277–282. 2023. | |
Zhang N, Hu XY, Dong XX, et al: Research progress on animal models of hyperuricemia. Acta Kunming Med Univ. 40:129–134. 2019.(In Chinese). |