Open Access

Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review

  • Authors:
    • Nor Atiqah Jusril
    • Khamsah Suryati Mohd
    • Nurliana Abd Mutalib
    • Ainur Awanis Mohd Badiazaman
  • View Affiliations

  • Published online on: November 5, 2024     https://doi.org/10.3892/br.2024.1887
  • Article Number: 9
  • Copyright: © Jusril et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Propolis is a sticky substance produced by stingless bees for construction and defence of their hive. It has notable anti‑inflammatory, antioxidant, antibacterial, antifungal, anti‑hyperglycemic, and wound healing effects. The present review summarised and examined the phytochemical properties, mode of action and current research prospects of Malaysian propolis. A database search using Google Scholar, Web of Science and ScienceDirect generated 780 references; 30 relevant articles were included in the present review, of which 23 were in vitro studies and 7 were in vivo or animal studies. Propolis demonstrated antioxidant, antibacterial, antifungal, anti‑inflammatory and anti‑hyperglycemic properties, indicating potential as a wound healing agent. Despite favourable findings, due to the scarcity of studies in the literature, more in‑depth research and clinical validation on the synergistic effects, efficacy and optimum dosage of propolis are needed.
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January-2025
Volume 22 Issue 1

Print ISSN: 2049-9434
Online ISSN:2049-9442

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Spandidos Publications style
Jusril NA, Mohd KS, Abd Mutalib N and Mohd Badiazaman AA: Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review. Biomed Rep 22: 9, 2025.
APA
Jusril, N.A., Mohd, K.S., Abd Mutalib, N., & Mohd Badiazaman, A.A. (2025). Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review. Biomedical Reports, 22, 9. https://doi.org/10.3892/br.2024.1887
MLA
Jusril, N. A., Mohd, K. S., Abd Mutalib, N., Mohd Badiazaman, A. A."Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review". Biomedical Reports 22.1 (2025): 9.
Chicago
Jusril, N. A., Mohd, K. S., Abd Mutalib, N., Mohd Badiazaman, A. A."Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review". Biomedical Reports 22, no. 1 (2025): 9. https://doi.org/10.3892/br.2024.1887