1
|
Weidinger S and Novak N: Atopic
dermatitis. Lancet. 387:1109–1122. 2016.PubMed/NCBI View Article : Google Scholar
|
2
|
Newsom M, Bashyam AM, Balogh EA, Feldman
SR and Strowd LC: New and emerging systemic treatments for atopic
dermatitis. Drugs. 80:1041–1052. 2020.PubMed/NCBI View Article : Google Scholar
|
3
|
Bieber T: Atopic dermatitis: An expanding
therapeutic pipeline for a complex disease. Nat Rev Drug Discov.
21:21–40. 2022.PubMed/NCBI View Article : Google Scholar
|
4
|
Zhou G, Huang Y and Chu M: Clinical trials
of antibody drugs in the treatments of atopic dermatitis. Front Med
(Lausanne). 10(1229539)2023.PubMed/NCBI View Article : Google Scholar
|
5
|
Hong J, Buddenkotte J, Berger TG and
Steinhoff M: Management of itch in atopic dermatitis. Semin Cutan
Med Surg. 30:71–86. 2011.PubMed/NCBI View Article : Google Scholar
|
6
|
Kychygina A, Cassagne M, Tauber M, Galiacy
S, Paul C, Fournié P and Simon M: Dupilumab-associated adverse
events during treatment of allergic diseases. Clin Rev Allergy
Immunol. 62:519–533. 2022.PubMed/NCBI View Article : Google Scholar
|
7
|
Gong T, Liu L, Jiang W and Zhou R:
DAMP-sensing receptors in sterile inflammation and inflammatory
diseases. Nat Rev Immunol. 20:95–112. 2020.PubMed/NCBI View Article : Google Scholar
|
8
|
Tamagawa-Mineoka R: Toll-like receptors:
Their roles in pathomechanisms of atopic dermatitis. Front Immunol.
14(1239244)2023.PubMed/NCBI View Article : Google Scholar
|
9
|
Akira S, Uematsu S and Takeuchi O:
Pathogen recognition and innate immunity. Cell. 124:783–801.
2006.PubMed/NCBI View Article : Google Scholar
|
10
|
Garcia-Manero G, Jabbour EJ, Konopleva MY,
Daver NG, Borthakur G, DiNardo CD, Bose P, Patel P, Komrokji RS,
Shastri A, et al: A clinical study of tomaralimab (OPN-305), a
toll-like receptor 2 (TLR-2) antibody, in heavily pre-treated
transfusion dependent patients with lower risk myelodysplastic
syndromes (MDS) that have received and failed on prior
hypomethylating agent (HMA) therapy. Blood. 132(798)2018.
|
11
|
Yeo H, Ahn SS, Ou S, Yun SJ, Lim Y, Koh D,
Lee YH and Shin SY: The EGR1-Artemin axis in keratinocytes enhances
the innervation of epidermal sensory neurons during skin
inflammation induced by house dust mite extract from
Dermatophagoidesfarinae. J Invest Dermatol. 144:1817–1828.e17.
2024.PubMed/NCBI View Article : Google Scholar
|
12
|
Riedl R, Kühn A, Rietz D, Hebecker B,
Glowalla KG, Peltner LK, Jordan PM, Werz O, Lorkowski S, Wiegand C
and Wallert M: Establishment and characterization of mild atopic
dermatitis in the DNCB-induced mouse model. Int J Mol Sci.
24(12325)2023.PubMed/NCBI View Article : Google Scholar
|
13
|
Toyama S, Moniaga CS, Nakae S, Kurosawa M,
Ogawa H, Tominaga M and Takamori K: Regulatory T cells exhibit
interleukin-33-dependent migratory behavior during skin barrier
disruption. Int J Mol Sci. 22(7443)2021.PubMed/NCBI View Article : Google Scholar
|
14
|
Paci A, Desnoyer A, Delahousse J, Blondel
L, Maritaz C, Chaput N, Mir O and Broutin S:
Pharmacokinetic/pharmacodynamic relationship of therapeutic
monoclonal antibodies used in oncology: Part 1, monoclonal
antibodies, antibody-drug conjugates and bispecific T-cell
engagers. Eur J Cancer. 128:107–118. 2020.PubMed/NCBI View Article : Google Scholar
|
15
|
Tao Z, Liu W, Chen Q, Zhang L, She K, Zhao
G, Liang L, Chen X, Yang Y, Song Q and Lu F: Blocking Th2 signaling
pathway alleviates the clinical symptoms and inflammation in
allergic conjunctivitis. Invest Ophthalmol Vis Sci.
64(30)2023.PubMed/NCBI View Article : Google Scholar
|
16
|
Yeo H, Ahn SS, Lee JY, Jung E, Jeong M,
Kang GS, Ahn S, Lee Y, Koh D, Lee YH, et al: Disrupting the DNA
binding of EGR-1 with a small-molecule inhibitor ameliorates 2,
4-dinitrochlorobenzene-induced skin inflammation. J Invest
Dermatol. 141:1851–1855. 2021.PubMed/NCBI View Article : Google Scholar
|
17
|
Yeo H, Lee YH, Koh D, Lim Y and Shin SY:
Chrysin inhibits NF-κB-dependent CCL5 transcription by targeting
IκB kinase in the atopic dermatitis-like inflammatory
microenvironment. Int J Mol Sci. 21(7348)2020.PubMed/NCBI View Article : Google Scholar
|
18
|
Yeo H, Lee YH, Ahn SS, Jung E, Lim Y and
Shin SY: Chrysin inhibits TNFα-induced TSLP expression through
downregulation of EGR1 expression in keratinocytes. Int J Mol Sci.
22(4350)2021.PubMed/NCBI View Article : Google Scholar
|
19
|
Ahn SS, Lee YH, Yeo H, Jung E, Lim Y and
Shin SY: Saikosaponin A and saikosaponin C reduce TNF-α-induced
TSLP expression through inhibition of MAPK-mediated EGR1 expression
in HaCaT keratinocytes. Int J Mol Sci. 23(4857)2022.PubMed/NCBI View Article : Google Scholar
|
20
|
Ahn SS, Yeo H, Jung E, Lim Y, Lee YH and
Shin SY: FRA1:c-JUN:HDAC1 complex down-regulates filaggrin
expression upon TNFα and IFNγ stimulation in keratinocytes. Proc
Natl Acad Sci USA. 119(e2123451119)2022.PubMed/NCBI View Article : Google Scholar
|
21
|
Sandilands A, Sutherland C, Irvine AD and
McLean WHI: Filaggrin in the frontline: Role in skin barrier
function and disease. J Cell Sci. 122:1285–1294. 2009.PubMed/NCBI View Article : Google Scholar
|
22
|
Cabanillas B and Novak N: Atopic
dermatitis and filaggrin. Curr Opin Immunol. 42:1–8.
2016.PubMed/NCBI View Article : Google Scholar
|
23
|
Liu YJ: Thymic stromal lymphopoietin:
Master switch for allergic inflammation. J Exp Med. 203:269–273.
2006.PubMed/NCBI View Article : Google Scholar
|
24
|
Brandt EB and Sivaprasad U: Th2 cytokines
and atopic dermatitis. J Clin Cell Immunol. 2(110)2011.PubMed/NCBI View Article : Google Scholar
|
25
|
Ando T, Matsumoto K, Namiranian S,
Yamashita H, Glatthorn H, Kimura M, Dolan BR, Lee JJ, Galli SJ,
Kawakami Y, et al: Mast cells are required for full expression of
allergen/SEB-induced skin inflammation. J Invest Dermatol.
133:2695–2705. 2013.PubMed/NCBI View Article : Google Scholar
|
26
|
Girolomoni G and Pastore S: The role of
keratinocytes in the pathogenesis of atopic dermatitis. J Am Acad
Dermatol. 45 (1 Suppl):S25–S28. 2001.PubMed/NCBI View Article : Google Scholar
|
27
|
Imai Y: Interleukin-33 in atopic
dermatitis. J Dermatol Sci. 96:2–7. 2019.PubMed/NCBI View Article : Google Scholar
|
28
|
Bianchi ME and Beltrame M: Upwardly mobile
proteins. Workshop: the role of HMG proteins in chromatin
structure, gene expression and neoplasia. EMBO Rep. 1:109–114.
2000.PubMed/NCBI View Article : Google Scholar
|
29
|
Scaffidi P, Misteli T and Bianchi ME:
Release of chromatin protein HMGB1 by necrotic cells triggers
inflammation. Nature. 418:191–195. 2002.PubMed/NCBI View Article : Google Scholar
|
30
|
Yu M, Wang H, Ding A, Golenbock DT, Latz
E, Czura CJ, Fenton MJ, Tracey KJ and Yang H: HMGB1 signals through
toll-like receptor (TLR) 4 and TLR2. Shock. 26:174–179.
2006.PubMed/NCBI View Article : Google Scholar
|
31
|
Kawai T and Akira S: The role of
pattern-recognition receptors in innate immunity: Update on
Toll-like receptors. Nat Immunol. 11:373–384. 2010.PubMed/NCBI View
Article : Google Scholar
|
32
|
Travers JB, Kozman A, Mousdicas N, Saha C,
Landis M, Al-Hassani M, Yao W, Yao Y, Hyatt AM, Sheehan MP, et al:
Infected atopic dermatitis lesions contain pharmacologic amounts of
lipoteichoic acid. J Allergy Clin Immunol. 125:146–152.e1-e2.
2010.PubMed/NCBI View Article : Google Scholar
|
33
|
Kaesler S, Volz T, Skabytska Y, Köberle M,
Hein U, Chen KM, Guenova E, Wölbing F, Röcken M and Biedermann T:
Toll-like receptor 2 ligands promote chronic atopic dermatitis
through IL-4-mediated suppression of IL-10. J Allergy Clin Immunol.
134:92–99. 2014.PubMed/NCBI View Article : Google Scholar
|
34
|
Werfel T, Allam JP, Biedermann T, Eyerich
K, Gilles S, Guttman-Yassky E, Hoetzenecker W, Knol E, Simon HU,
Wollenberg A, et al: Cellular and molecular immunologic mechanisms
in patients with atopic dermatitis. J Allergy Clin Immunol.
138:336–349. 2016.PubMed/NCBI View Article : Google Scholar
|
35
|
Ebina-Shibuya R and Leonard WJ: Role of
thymic stromal lymphopoietin in allergy and beyond. Nat Rev
Immunol. 23:24–37. 2023.PubMed/NCBI View Article : Google Scholar
|
36
|
Wilson SR, Thé L, Batia LM, Beattie K,
Katibah GE, McClain SP, Pellegrino M, Estandian DM and Bautista DM:
The epithelial cell-derived atopic dermatitis cytokine TSLP
activates neurons to induce itch. Cell. 155:285–295.
2013.PubMed/NCBI View Article : Google Scholar
|
37
|
Gibbs BF, Patsinakidis N and Raap U: Role
of the pruritic cytokine IL-31 in autoimmune skin diseases. Front
Immunol. 10(1383)2019.PubMed/NCBI View Article : Google Scholar
|
38
|
Meng J, Moriyama M, Feld M, Buddenkotte J,
Buhl T, Szöllösi A, Zhang J, Miller P, Ghetti A, Fischer M, et al:
New mechanism underlying IL-31-induced atopic dermatitis. J Allergy
Clin Immunol. 141:1677–1689.e8. 2018.PubMed/NCBI View Article : Google Scholar
|
39
|
McFadden J, Dearman R, White J, Basketter
D and Kimber I: The hapten-atopy hypothesis II: The ‘cutaneous
hapten paradox’. Clin Exp Allergy. 41:327–337. 2011.PubMed/NCBI View Article : Google Scholar
|
40
|
Park JS, Gamboni-Robertson F, He Q,
Svetkauskaite D, Kim JY, Strassheim D, Sohn JW, Yamada S, Maruyama
I, Banerjee A, et al: High mobility group box 1 protein interacts
with multiple Toll-like receptors. Am J Physiol Cell Physiol.
290:C917–C924. 2006.PubMed/NCBI View Article : Google Scholar
|
41
|
Venereau E, Casalgrandi M, Schiraldi M,
Antoine DJ, Cattaneo A, De Marchis F, Liu J, Antonelli A, Preti A,
Raeli L, et al: Mutually exclusive redox forms of HMGB1 promote
cell recruitment or proinflammatory cytokine release. J Exp Med.
209:1519–1528. 2012.PubMed/NCBI View Article : Google Scholar
|