Acute myocardial infarction due to spontaneous coronary artery dissection in a young male with systemic lupus erythematosus: A case report

  • Authors:
    • Yunyi Li
    • Quan Zhou
    • Xiao Meng
  • View Affiliations

  • Published online on: April 9, 2024     https://doi.org/10.3892/etm.2024.12534
  • Article Number: 246
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Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease which typically presents in young women. Patients with SLE exhibit features of accelerated atherosclerosis. Here, the present study reported a rare case of acute myocardial infarction (AMI) in a male patient diagnosed with SLE. A 29‑year‑old male with no cardiovascular history was diagnosed with AMI and underwent coronary angiography, which showed a long‑extended spiral‑shaped dissection of the right coronary artery (RCA). The patient's autoimmune panel tested positive for antinuclear, anti‑nuclear ribonucleoprotein/Smith and anti‑Sjogren's syndrome A antibodies. The patient was diagnosed with SLE and was administered prednisone, hydroxychloroquine and calcium carbonate therapy. At the 3‑month follow‑up, a repeat coronary angiography showed no dissection in the RCA. Intravascular ultrasound and optical coherence tomography also showed an isolated atherosclerotic lesion without arterial dissection in the RCA. To the best of our knowledge, this is the first reported case of a male patient with SLE who developed myocardial infarction caused by spontaneous coronary artery dissection (SCAD). The present report may provide new insights into possible future treatments for SCAD. SCAD should be considered in patients with SLE and AMI, particularly in young patients without cardiovascular risk factors. Early diagnosis of SCAD is important to provide accurate therapy that differs from the treatment of AMI caused by atherosclerosis.
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June-2024
Volume 27 Issue 6

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Li Y, Zhou Q and Meng X: Acute myocardial infarction due to spontaneous coronary artery dissection in a young male with systemic lupus erythematosus: A case report. Exp Ther Med 27: 246, 2024.
APA
Li, Y., Zhou, Q., & Meng, X. (2024). Acute myocardial infarction due to spontaneous coronary artery dissection in a young male with systemic lupus erythematosus: A case report. Experimental and Therapeutic Medicine, 27, 246. https://doi.org/10.3892/etm.2024.12534
MLA
Li, Y., Zhou, Q., Meng, X."Acute myocardial infarction due to spontaneous coronary artery dissection in a young male with systemic lupus erythematosus: A case report". Experimental and Therapeutic Medicine 27.6 (2024): 246.
Chicago
Li, Y., Zhou, Q., Meng, X."Acute myocardial infarction due to spontaneous coronary artery dissection in a young male with systemic lupus erythematosus: A case report". Experimental and Therapeutic Medicine 27, no. 6 (2024): 246. https://doi.org/10.3892/etm.2024.12534