Open Access

Application of 3D‑printed porous titanium interbody fusion cage vs. polyether ether ketone interbody fusion cage in anterior cervical discectomy and fusion: A systematic review and meta‑analysis update

  • Authors:
    • Wan-Jing Zhai
    • Lun Liu
    • Yu-Hao Gao
    • Shi-Lei Qin
    • Peng-Fei Han
    • Yun-Feng Xu
  • View Affiliations

  • Published online on: May 21, 2024     https://doi.org/10.3892/etm.2024.12579
  • Article Number: 290
  • Copyright: © Zhai et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The present study aimed to compare the differences between 3D‑printed porous titanium and polyether ether ketone (PEEK) interbody fusion cages for anterior cervical discectomy and fusion (ACDF). Literature on the application of 3D‑printed porous titanium and PEEK interbody fusion cages for ACDF was searched in the PubMed, Web of Science, Embase, China National Knowledge Infrastructure, Wanfang and VIP databases. A total of 1,181 articles were retrieved and 12 were finally included. The Cochrane bias risk assessment criteria and Newcastle‑Ottawa scale were used for quality evaluation and Review Manager 5.4 was used for data analysis. The 3D cage group was superior to the PEEK cage group in terms of operative time [mean difference (MD): ‑7.68; 95% confidence interval (CI): ‑11.08, ‑4.29; P<0.00001], intraoperative blood loss (MD: ‑6.17; 95%CI: ‑10.56, ‑1.78; P=0.006), hospitalization time (MD: ‑0.57; 95%CI: ‑0.86, ‑0.28: P=0.0001), postoperative complications [odds ratio (OR): 0.35; 95%CI: 0.15, 0.80; P=0.01], C2‑7 Cobb angle (MD: 2.85; 95%CI: 1.45, 4.24; P<0.0001), intervertebral space height (MD: 1.20; 95%CI: 0.54, 1.87; P=0.0004), Japanese Orthopaedic Association Assessment of Treatment (MD: 0.69; 95%CI: 0.24, 1.15; P=0.003) and visual analogue scale score (MD: ‑0.43; 95%CI: ‑0.78, ‑0.07; P=0.02). The difference was statistically significant, while there was no significant difference between the two groups in terms of fusion rate (OR: 1.74; 95%CI: 0.71, 4.27; P=0.23). The use of 3D‑printed porous titanium interbody fusion cage in ACDF has the advantages of short operation time, less bleeding loss, shorter hospitalization time and fewer postoperative complications. It can better maintain the cervical curvature and intervertebral height, relieve pain and accelerate postoperative functional recovery.
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July-2024
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Spandidos Publications style
Zhai W, Liu L, Gao Y, Qin S, Han P and Xu Y: Application of 3D‑printed porous titanium interbody fusion cage vs. polyether ether ketone interbody fusion cage in anterior cervical discectomy and fusion: A systematic review and meta‑analysis update. Exp Ther Med 28: 290, 2024.
APA
Zhai, W., Liu, L., Gao, Y., Qin, S., Han, P., & Xu, Y. (2024). Application of 3D‑printed porous titanium interbody fusion cage vs. polyether ether ketone interbody fusion cage in anterior cervical discectomy and fusion: A systematic review and meta‑analysis update. Experimental and Therapeutic Medicine, 28, 290. https://doi.org/10.3892/etm.2024.12579
MLA
Zhai, W., Liu, L., Gao, Y., Qin, S., Han, P., Xu, Y."Application of 3D‑printed porous titanium interbody fusion cage vs. polyether ether ketone interbody fusion cage in anterior cervical discectomy and fusion: A systematic review and meta‑analysis update". Experimental and Therapeutic Medicine 28.1 (2024): 290.
Chicago
Zhai, W., Liu, L., Gao, Y., Qin, S., Han, P., Xu, Y."Application of 3D‑printed porous titanium interbody fusion cage vs. polyether ether ketone interbody fusion cage in anterior cervical discectomy and fusion: A systematic review and meta‑analysis update". Experimental and Therapeutic Medicine 28, no. 1 (2024): 290. https://doi.org/10.3892/etm.2024.12579