Open Access

Epileptic seizures as an initial symptom for Sturge‑Weber syndrome type III: A report of two cases

  • Authors:
    • Yaping Wang
    • Guifu Geng
    • Wandong Hu
    • Huan Zhang
    • Yong Liu
    • Zaifen Gao
    • Hongwei Zhang
    • Jianguo Shi
  • View Affiliations

  • Published online on: May 24, 2024     https://doi.org/10.3892/etm.2024.12588
  • Article Number: 299
  • Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Sturge‑Weber syndrome (SWS) type III, a rare neurocutaneous disorder, presents diagnostic challenges due to its variable clinical manifestations. The present study focuses on enhancing the understanding of this syndrome by conducting a detailed analysis of two pediatric cases and providing a comprehensive review of the existing literature. The cases, managed at the Children's Hospital Affiliated to Shandong University (Jinan, China), highlight the diverse clinical presentations and successful management strategies for SWS type III. In the first case, a 4‑year‑old male patient exhibited paroxysmal hemiplegia, epileptic seizures and cerebral angiographic findings indicative of left pia mater and venous malformation. The second case involved a 2.5‑year‑old male patient presenting with recurrent seizures and angiographic findings on the right side. Both cases underscore the importance of considering epileptic seizures, acquired and transient hemiplegia and cognitive impairments in the diagnosis of SWS type III. The present study provides insights into the effective use of both pharmacological and surgical interventions, drawing from the positive outcomes observed in these cases. The findings emphasize the need for heightened awareness and a meticulous approach in diagnosing and treating SWS type III, contributing to the better management and prognosis of this condition.
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July-2024
Volume 28 Issue 1

Print ISSN: 1792-0981
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Spandidos Publications style
Wang Y, Geng G, Hu W, Zhang H, Liu Y, Gao Z, Zhang H and Shi J: Epileptic seizures as an initial symptom for Sturge‑Weber syndrome type III: A report of two cases. Exp Ther Med 28: 299, 2024
APA
Wang, Y., Geng, G., Hu, W., Zhang, H., Liu, Y., Gao, Z. ... Shi, J. (2024). Epileptic seizures as an initial symptom for Sturge‑Weber syndrome type III: A report of two cases. Experimental and Therapeutic Medicine, 28, 299. https://doi.org/10.3892/etm.2024.12588
MLA
Wang, Y., Geng, G., Hu, W., Zhang, H., Liu, Y., Gao, Z., Zhang, H., Shi, J."Epileptic seizures as an initial symptom for Sturge‑Weber syndrome type III: A report of two cases". Experimental and Therapeutic Medicine 28.1 (2024): 299.
Chicago
Wang, Y., Geng, G., Hu, W., Zhang, H., Liu, Y., Gao, Z., Zhang, H., Shi, J."Epileptic seizures as an initial symptom for Sturge‑Weber syndrome type III: A report of two cases". Experimental and Therapeutic Medicine 28, no. 1 (2024): 299. https://doi.org/10.3892/etm.2024.12588