Right eye metastasis of small‑cell lung carcinoma: A case report

Zhu,Pei; Wang,Mingxing; Sun,Qingming; Dong,Wanhui

doi:10.3892/etm.2024.12607

Right eye metastasis of small‑cell lung carcinoma: A case report

Authors:
- Pei Zhu
- Mingxing Wang
- Qingming Sun
- Wanhui Dong
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Affiliations: Department of Medical Oncology, Lu'an Hospital Affiliated To Anhui University of Chinese Medicine, Lu'an, Anhui 237006, P.R. China
Published online on: June 14, 2024 https://doi.org/10.3892/etm.2024.12607
Article Number: 318
Copyright: © Zhu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The incidence of eye metastasis from primary malignant tumors is low. Predominantly, these primary malignant tumors consist of breast and lung carcinoma. Ocular metastatic carcinoma is often clinically overlooked. In clinical practice, it is rare for small‑cell lung carcinoma (SCLC) to metastasize to the right eye. Early detection and treatment via the monitoring of clinical symptoms and auxiliary examinations of the eye are of great significance in preserving the patient's vision and improving their quality of life. Such treatments include radiotherapy or enucleation of the eyeball. A 54‑year‑old male patient with SCLC experienced a decline in vision and blurred vision during his systemic treatment using combined enverolumab and etoposide and cisplatin. Upon examination, including fundus photography, ocular B‑scan and magnetic resonance imaging, a right eye metastasis was suspected. Within a short period of time, the patient experienced significant pain and blindness in the right eye, which required surgical removal of the right eyeball. Postoperative pathology confirmed metastasis. After six cycles of treatment, the primary lesion in the lung reduced in size. By reporting this case of SCLC metastasis to the right eye, we aim to provide a reference for the clinical diagnosis and treatment of ocular metastatic carcinoma.

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