Open Access

Imatinib‑induced gynecomastia: A case report

  • Authors:
    • Xiao-Lan Li
    • Min Li
    • Sheng-Ke Tu
    • Hong-Jie Fan
    • Zi-Wei Shi
    • Ling-Zhi Wang
    • Juan Tian
    • Kui Song
  • View Affiliations

  • Published online on: September 11, 2024     https://doi.org/10.3892/etm.2024.12714
  • Article Number: 425
  • Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Chronic myeloid leukemia is a myeloproliferative neoplasm characterized by the unregulated and abnormal proliferation of both mature and immature granulocytes, which results in the proliferation of peripheral blood leukocytes. Imatinib, a tyrosine kinase inhibitor, is the first‑line treatment for patients diagnosed with chronic myeloid leukemia. However, despite its favorable safety profile, imatinib use is associated with a number of side effects. Gynecomastia is a rare adverse effect of imatinib treatment and may be associated with an imbalance in sex hormones. The present study reports the case of a patient with chronic myeloid leukemia diagnosed with gynecomastia after imatinib treatment. The aim of the present report was to highlight to clinicians this adverse reaction to imatinib treatment and investigate a treatment strategy with fewer side effects.
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November-2024
Volume 28 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
Li X, Li M, Tu S, Fan H, Shi Z, Wang L, Tian J and Song K: Imatinib‑induced gynecomastia: A case report. Exp Ther Med 28: 425, 2024.
APA
Li, X., Li, M., Tu, S., Fan, H., Shi, Z., Wang, L. ... Song, K. (2024). Imatinib‑induced gynecomastia: A case report. Experimental and Therapeutic Medicine, 28, 425. https://doi.org/10.3892/etm.2024.12714
MLA
Li, X., Li, M., Tu, S., Fan, H., Shi, Z., Wang, L., Tian, J., Song, K."Imatinib‑induced gynecomastia: A case report". Experimental and Therapeutic Medicine 28.5 (2024): 425.
Chicago
Li, X., Li, M., Tu, S., Fan, H., Shi, Z., Wang, L., Tian, J., Song, K."Imatinib‑induced gynecomastia: A case report". Experimental and Therapeutic Medicine 28, no. 5 (2024): 425. https://doi.org/10.3892/etm.2024.12714