Potential role of G protein‑coupled receptor 124 in cardiovascular and cerebrovascular disease (Review)
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- Published online on: October 23, 2024 https://doi.org/10.3892/etm.2024.12752
- Article Number: 2
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Copyright: © Lin et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
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Abstract
G protein‑coupled receptor 124 (GPR124) has a key role in regulating the proliferation and differentiation of endothelial cells, activating inflammatory bodies and promoting angiogenesis and other processes, thus affecting various pathological and physiological processes in the body. GPR124 is vital for promoting the development of the nervous system and maintaining the stability of the blood‑brain barrier, and is also associated with cardiovascular and cerebrovascular diseases and cancer. This article will elaborate on the biological information regarding GPR124 published in recent years and its possible related signaling pathways in the field of diseases and provide a reference for further revealing the role of GPR124 in the occurrence and development of diseases.
