Synchronous thyroid medullary cancer and thyroid hemiagenesis: A case report

Li,Chunyang; Zhang,Chengbin; Ma,Chao; Wang,Yonghui; Duan,Quanhong

doi:10.3892/etm.2025.12827

Synchronous thyroid medullary cancer and thyroid hemiagenesis: A case report

Authors:
- Chunyang Li
- Chengbin Zhang
- Chao Ma
- Yonghui Wang
- Quanhong Duan
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Affiliations: Department of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong 261041, P.R. China, Department of Surgery, Hongshagou Town Hospital, Anqiu, Weifang, Shandong 261041, P.R. China, Department of Thyroid and Breast Surgery, Anqiu People's Hospital, Weifang, Shandong 261041, P.R. China, Department of Thyroid and Breast Surgery, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China
Published online on: February 18, 2025 https://doi.org/10.3892/etm.2025.12827
Article Number: 77
Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Thyroid hemiagenesis (TH) is a rare, congenital malformation defined as the absence of one thyroid lobe with or without an isthmus. By contrast, medullary thyroid cancer (MTC) is a rare thyroid malignancy, arises from parafollicular C cells. In the current study, a 33‑year‑old man presented with a small mass on the left side of the neck. Ultrasonography indicated a hyperechoic nodule in the left lobe of the thyroid gland and the right thyroid lobe could not be visualized. The patient underwent fine‑needle aspiration cytology and MTC was suspected. The patient underwent total thyroidectomy, bilateral central lymph node dissection and left cervical compartment dissection. L‑thyroxine (100 µg/per day) commenced immediately following thyroidectomy. During follow‑up (monitored every 3 months), the patient remained healthy with no evidence of recurrence.

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