1
|
Cheng H and Leblond CP: Origin,
differentiation and renewal of the four main epithelial cell types
in the mouse small intestine. V Unitarian Theory of the origin of
the four epithelial cell types. Am J Anat. 141:537–561. 1974.
View Article : Google Scholar : PubMed/NCBI
|
2
|
Barker N, van Es JH, Kuipers J, Kujala P,
van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H,
Peters PJ, et al: Identification of stem cells in small intestine
and colon by marker gene Lgr5. Nature. 449:1003–1007. 2007.
View Article : Google Scholar : PubMed/NCBI
|
3
|
Potten CS: Extreme sensitivity of some
intestinal crypt cells to X and gamma irradiation. Nature.
269:518–521. 1977. View
Article : Google Scholar : PubMed/NCBI
|
4
|
Sangiorgi E and Capecchi MR: Bmi1 is
expressed in vivo in intestinal stem cells. Nat Genet. 40:915–920.
2008. View
Article : Google Scholar : PubMed/NCBI
|
5
|
Takeda N, Jain R, LeBoeuf MR, Wang Q, Lu
MM and Epstein JA: Interconversion between intestinal stem cell
populations in distinct niches. Science. 334:1420–1424. 2011.
View Article : Google Scholar : PubMed/NCBI
|
6
|
Montgomery RK, Carlone DL, Richmond CA,
Farilla L, Kranendonk ME, Henderson DE, Baffour-Awuah NY, Ambruzs
DM, Fogli LK, Algra S, et al: Mouse telomerase reverse
transcriptase (mTert) expression marks slowly cycling intestinal
stem cells. Proc Natl Acad Sci USA. 108:179–184. 2011. View Article : Google Scholar :
|
7
|
Powell AE, Wang Y, Li Y, Poulin EJ, Means
AL, Washington MK, Higginbotham JN, Juchheim A, Prasad N, Levy SE,
et al: The pan-ErbB negative regulator Lrig1 is an intestinal stem
cell marker that functions as a tumor suppressor. Cell.
149:146–158. 2012. View Article : Google Scholar : PubMed/NCBI
|
8
|
Sato T, van Es JH, Snippert HJ, Stange DE,
Vries RG, van den Born M, Barker N, Shroyer NF, van de Wetering M
and Clevers H: Paneth cells constitute the niche for Lgr5 stem
cells in intestinal crypts. Nature. 469:415–418. 2011. View Article : Google Scholar
|
9
|
Korinek V, Barker N, Moerer P, van
Donselaar E, Huls G, Peters PJ and Clevers H: Depletion of
epithelial stem-cell compartments in the small intestine of mice
lacking Tcf-4. Nat Genet. 19:379–383. 1998. View Article : Google Scholar : PubMed/NCBI
|
10
|
Pellegrinet L, Rodilla V, Liu Z, Chen S,
Koch U, Espinosa L, Kaestner KH, Kopan R, Lewis J and Radtke F:
Dll1- and dll4-mediated notch signaling are required for
homeostasis of intestinal stem cells. Gastroenterology.
140:1230–1240. e1231–1237. 2011. View Article : Google Scholar : PubMed/NCBI
|
11
|
Sato T, Vries RG, Snippert HJ, van de
Wetering M, Barker N, Stange DE, van Es JH, Abo A, Kujala P, Peters
PJ, et al: Single Lgr5 stem cells build crypt-villus structures in
vitro without a mesenchymal niche. Nature. 459:262–265. 2009.
View Article : Google Scholar : PubMed/NCBI
|
12
|
Haramis AP, Begthel H, van den Born M, van
Es J, Jonkheer S, Offerhaus GJ and Clevers H: De novo crypt
formation and juvenile polyposis on BMP inhibition in mouse
intestine. Science. 303:1684–1686. 2004. View Article : Google Scholar : PubMed/NCBI
|
13
|
Ivanov S, Liao SY, Ivanova A,
Danilkovitch-Miagkova A, Tarasova N, Weirich G, Merrill MJ,
Proescholdt MA, Oldfield EH, Lee J, et al: Expression of
hypoxia-inducible cell-surface transmembrane carbonic anhydrases in
human cancer. Am J Pathol. 158:905–919. 2001. View Article : Google Scholar : PubMed/NCBI
|
14
|
Liao SY, Lerman MI and Stanbridge EJ:
Expression of trans-membrane carbonic anhydrases, CAIX and CAXII,
in human development. BMC Dev Biol. 9:222009. View Article : Google Scholar
|
15
|
Hussain SA, Ganesan R, Reynolds G, Gross
L, Stevens A, Pastorek J, Murray PG, Perunovic B, Anwar MS,
Billingham L, et al: Hypoxia-regulated carbonic anhydrase IX
expression is associated with poor survival in patients with
invasive breast cancer. Br J Cancer. 96:104–109. 2007. View Article : Google Scholar : PubMed/NCBI
|
16
|
Ilie M, Mazure NM, Hofman V, Ammadi RE,
Ortholan C, Bonnetaud C, Havet K, Venissac N, Mograbi B, Mouroux J,
et al: High levels of carbonic anhydrase IX in tumour tissue and
plasma are biomarkers of poor prognostic in patients with non-small
cell lung cancer. Br J Cancer. 102:1627–1635. 2010. View Article : Google Scholar : PubMed/NCBI
|
17
|
Saarnio J, Parkkila S, Parkkila AK,
Haukipuro K, Pastoreková S, Pastorek J, Kairaluoma MI and Karttunen
TJ: Immunohistochemical study of colorectal tumors for expression
of a novel transmembrane carbonic anhydrase, MN/CA IX, with
potential value as a marker of cell proliferation. Am J Pathol.
153:279–285. 1998. View Article : Google Scholar : PubMed/NCBI
|
18
|
Jubb AM, Turley H, Moeller HC, Steers G,
Han C, Li JL, Leek R, Tan EY, Singh B, Mortensen NJ, et al:
Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in
colon cancer. Br J Cancer. 101:1749–1757. 2009. View Article : Google Scholar : PubMed/NCBI
|
19
|
Korkeila E, Talvinen K, Jaakkola PM, Minn
H, Syrjänen K, Sundström J and Pyrhönen S: Expression of carbonic
anhydrase IX suggests poor outcome in rectal cancer. Br J Cancer.
100:874–880. 2009. View Article : Google Scholar : PubMed/NCBI
|
20
|
Sato T, Stange DE, Ferrante M, Vries RG,
Van Es JH, Van den Brink S, Van Houdt WJ, Pronk A, Van Gorp J,
Siersema PD, et al: Long-term expansion of epithelial organoids
from human colon, adenoma, adenocarcinoma, and Barrett's
epithelium. Gastroenterology. 141:1762–1772. 2011. View Article : Google Scholar : PubMed/NCBI
|
21
|
Rothenberg ME, Nusse Y, Kalisky T, Lee JJ,
Dalerba P, Scheeren F, Lobo N, Kulkarni S, Sim S, Qian D, et al:
Identification of a cKit(+) colonic crypt base secretory cell that
supports Lgr5(+) stem cells in mice. Gastroenterology.
142:1195–1205 e1196. 2012. View Article : Google Scholar : PubMed/NCBI
|
22
|
Gracz AD, Fuller MK, Wang F, Li L,
Stelzner M, Dunn JC, Martin MG and Magness ST: Brief report: CD24
and CD44 mark human intestinal epithelial cell populations with
characteristics of active and facultative stem cells. Stem Cells.
31:2024–2030. 2013. View Article : Google Scholar : PubMed/NCBI
|
23
|
Smith PD, Smythies LE, Shen R,
Greenwell-Wild T, Gliozzi M and Wahl SM: Intestinal macrophages and
response to microbial encroachment. Mucosal Immunol. 4:31–42. 2011.
View Article : Google Scholar
|
24
|
Jho EH, Zhang T, Domon C, Joo CK, Freund
JN and Costantini F: Wnt/beta-catenin/Tcf signaling induces the
transcription of Axin2, a negative regulator of the signaling
pathway. Mol Cell Biol. 22:1172–1183. 2002. View Article : Google Scholar : PubMed/NCBI
|
25
|
Kang K, Peng X, Zhang X, Wang Y, Zhang L,
Gao L, Weng T, Zhang H, Ramchandran R, Raj JU, et al: MicroRNA-124
suppresses the transactivation of nuclear factor of activated T
cells by targeting multiple genes and inhibits the proliferation of
pulmonary artery smooth muscle cells. J Biol Chem. 288:25414–25427.
2013. View Article : Google Scholar : PubMed/NCBI
|
26
|
Barathova M, Takacova M, Holotnakova T,
Gibadulinova A, Ohradanova A, Zatovicova M, Hulikova A, Kopacek J,
Parkkila S, Supuran CT, et al: Alternative splicing variant of the
hypoxia marker carbonic anhydrase IX expressed independently of
hypoxia and tumour phenotype. Br J Cancer. 98:129–136. 2008.
View Article : Google Scholar
|
27
|
Radu I: Morphological aspects of endocrine
cells in human fetal gastrointestinal mucosa. Microscopical,
electronmicroscopical and immunohistochemical studies. Rom J
Morphol Embryol. 40:93–98. 1994.PubMed/NCBI
|
28
|
Rindi G, Leiter AB, Kopin AS, Bordi C and
Solcia E: The ‘normal’ endocrine cell of the gut: Changing concepts
and new evidences. Ann NY Acad Sci. 1014:1–12. 2004. View Article : Google Scholar
|
29
|
Buczacki SJ, Zecchini HI, Nicholson AM,
Russell R, Vermeulen L, Kemp R and Winton DJ: Intestinal
label-retaining cells are secretory precursors expressing Lgr5.
Nature. 495:65–69. 2013. View Article : Google Scholar : PubMed/NCBI
|
30
|
Hattori T, Takei N, Mizuno Y, Kato K and
Kohsaka S: Neurotrophic and neuroprotective effects of
neuron-specific enolase on cultured neurons from embryonic rat
brain. Neurosci Res. 21:191–198. 1995. View Article : Google Scholar : PubMed/NCBI
|
31
|
Leppilampi M, Karttunen TJ, Kivelä J, Gut
MO, Pastoreková S, Pastorek J and Parkkila S: Gastric pit cell
hyperplasia and glandular atrophy in carbonic anhydrase IX knockout
mice: Studies on two strains C57/BL6 and BALB/C. Transgenic Res.
14:655–663. 2005. View Article : Google Scholar : PubMed/NCBI
|
32
|
Gatenby RA and Gillies RJ: A
microenvironmental model of carcinogenesis. Nat Rev Cancer.
8:56–61. 2008. View Article : Google Scholar
|
33
|
Wykoff CC, Beasley NJ, Watson PH, Turner
KJ, Pastorek J, Sibtain A, Wilson GD, Turley H, Talks KL, Maxwell
PH, et al: Hypoxia-inducible expression of tumor-associated
carbonic anhydrases. Cancer Res. 60:7075–7083. 2000.
|
34
|
Kaluz S, Kaluzová M, Chrastina A, Olive
PL, Pastoreková S, Pastorek J, Lerman MI and Stanbridge EJ: Lowered
oxygen tension induces expression of the hypoxia marker MN/carbonic
anhydrase IX in the absence of hypoxia-inducible factor 1 alpha
stabilization: A role for phosphatidylinositol 3′-kinase. Cancer
Res. 62:4469–4477. 2002.PubMed/NCBI
|
35
|
Kaluz S, Kaluzová M and Stanbridge EJ:
Expression of the hypoxia marker carbonic anhydrase IX is
critically dependent on SP1 activity. Identification of a novel
type of hypoxia-responsive enhancer. Cancer Res. 63:917–922.
2003.PubMed/NCBI
|
36
|
Swietach P, Hulikova A, Vaughan-Jones RD
and Harris AL: New insights into the physiological role of carbonic
anhydrase IX in tumour pH regulation. Oncogene. 29:6509–6521. 2010.
View Article : Google Scholar : PubMed/NCBI
|
37
|
Kim BR, Shin HJ, Kim JY, Byun HJ, Lee JH,
Sung YK and Rho SB: Dickkopf-1 (DKK-1) interrupts FAK/PI3K/mTOR
pathway by interaction of carbonic anhydrase IX (CA9) in
tumorigenesis. Cell Signal. 24:1406–1413. 2012. View Article : Google Scholar : PubMed/NCBI
|
38
|
Rasheed S, Harris AL, Tekkis PP, Turley H,
Silver A, McDonald PJ, Talbot IC, Glynne-Jones R, Northover JM and
Guenther T: Assessment of microvessel density and carbonic
anhydrase-9 (CA-9) expression in rectal cancer. Pathol Res Pract.
205:1–9. 2009. View Article : Google Scholar
|
39
|
Svastová E, Zilka N, Zat'ovicová M,
Gibadulinová A, Ciampor F, Pastorek J and Pastoreková S: Carbonic
anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via
interaction with beta-catenin. Exp Cell Res. 290:332–345. 2003.
View Article : Google Scholar : PubMed/NCBI
|
40
|
Shin HJ, Rho SB, Jung DC, Han IO, Oh ES
and Kim JY: Carbonic anhydrase IX (CA9) modulates tumor-associated
cell migration and invasion. J Cell Sci. 124:1077–1087. 2011.
View Article : Google Scholar : PubMed/NCBI
|
41
|
Lou Y, McDonald PC, Oloumi A, Chia S,
Ostlund C, Ahmadi A, Kyle A, Auf dem Keller U, Leung S, Huntsman D,
et al: Targeting tumor hypoxia: Suppression of breast tumor growth
and metastasis by novel carbonic anhydrase IX inhibitors. Cancer
Res. 71:3364–3376. 2011. View Article : Google Scholar : PubMed/NCBI
|
42
|
Lock FE, McDonald PC, Lou Y, Serrano I,
Chafe SC, Ostlund C, Aparicio S, Winum JY, Supuran CT and Dedhar S:
Targeting carbonic anhydrase IX depletes breast cancer stem cells
within the hypoxic niche. Oncogene. 32:5210–5219. 2013. View Article : Google Scholar
|
43
|
Sansone P, Storci G, Tavolari S, Guarnieri
T, Giovannini C, Taffurelli M, Ceccarelli C, Santini D, Paterini P,
Marcu KB, et al: IL-6 triggers malignant features in mammospheres
from human ductal breast carcinoma and normal mammary gland. J Clin
Invest. 117:3988–4002. 2007. View Article : Google Scholar : PubMed/NCBI
|
44
|
Proescholdt MA, Merrill MJ, Stoerr EM,
Lohmeier A, Pohl F and Brawanski A: Function of carbonic anhydrase
IX in glioblastoma multiforme. Neuro Oncol. 14:1357–1366. 2012.
View Article : Google Scholar : PubMed/NCBI
|
45
|
Chia SK, Wykoff CC, Watson PH, Han C, Leek
RD, Pastorek J, Gatter KC, Ratcliffe P and Harris AL: Prognostic
significance of a novel hypoxia-regulated marker, carbonic
anhydrase IX, in invasive breast carcinoma. J Clin Oncol.
19:3660–3668. 2001.PubMed/NCBI
|
46
|
Driessen A, Landuyt W, Pastorekova S,
Moons J, Goethals L, Haustermans K, Nafteux P, Penninckx F, Geboes
K, Lerut T, et al: Expression of carbonic anhydrase IX (CA IX), a
hypoxia-related protein, rather than vascular-endothelial growth
factor (VEGF), a pro-angiogenic factor, correlates with an
extremely poor prognosis in esophageal and gastric adenocarcinomas.
Ann Surg. 243:334–340. 2006. View Article : Google Scholar : PubMed/NCBI
|
47
|
Bui MH, Seligson D, Han KR, Pantuck AJ,
Dorey FJ, Huang Y, Horvath S, Leibovich BC, Chopra S, Liao SY, et
al: Carbonic anhydrase IX is an independent predictor of survival
in advanced renal clear cell carcinoma: Implications for prognosis
and therapy. Clin Cancer Res. 9:802–811. 2003.PubMed/NCBI
|
48
|
Malentacchi F, Vinci S, Della Melina A,
Kuncova J, Villari D, Giannarini G, Nesi G, Selli C and Orlando C:
Splicing variants of carbonic anhydrase IX in bladder cancer and
urine sediments. Urol Oncol. 30:278–284. 2012. View Article : Google Scholar
|
49
|
Beasley NJ, Wykoff CC, Watson PH, Leek R,
Turley H, Gatter K, Pastorek J, Cox GJ, Ratcliffe P and Harris AL:
Carbonic anhydrase IX, an endogenous hypoxia marker, expression in
head and neck squamous cell carcinoma and its relationship to
hypoxia, necrosis, and microvessel density. Cancer Res.
61:5262–5267. 2001.PubMed/NCBI
|
50
|
Tokunaga T, Tomita A, Sugimoto K, Shimada
K, Iriyama C, Hirose T, Shirahata-Adachi M, Suzuki Y, Mizuno H,
Kiyoi H, et al: De novo diffuse large B-cell lymphoma with a CD20
immunohistochemistry-positive and flow cytometry-negative
phenotype: Molecular mechanisms and correlation with rituximab
sensitivity. Cancer Sci. 105:35–43. 2014. View Article : Google Scholar
|