1
|
Beiki O, Hall P, Ekbom A and Moradi T:
Breast cancer incidence and case fatality among 4.7 million women
in relation to social and ethnic background: A population-based
cohort study. Breast Cancer Res. 14:R52012. View Article : Google Scholar : PubMed/NCBI
|
2
|
Malfettone A, Saponaro C, Paradiso A,
Simone G and Mangia A: Peritumoral vascular invasion and NHERF1
expression define an immunophenotype of grade 2 invasive breast
cancer associated with poor prognosis. BMC Cancer. 12:1062012.
View Article : Google Scholar : PubMed/NCBI
|
3
|
Cowin P and Welch DR: Breast cancer
progression: Controversies and consensus in the molecular
mechanisms of metastasis and EMT. J Mammary Gland Biol Neoplasia.
12:99–102. 2007. View Article : Google Scholar
|
4
|
Naithani R, Huma LC, Moriarty RM,
McCormick DL and Mehta RG: Comprehensive review of cancer
chemopreventive agents evaluated in experimental carcinogenesis
models and clinical trials. Curr Med Chem. 15:1044–1071. 2008.
View Article : Google Scholar : PubMed/NCBI
|
5
|
Verschoyle RD, Steward WP and Gescher AJ:
Putative cancer chemopreventive agents of dietary origin-how safe
are they? Nutr Cancer. 59:152–162. 2007. View Article : Google Scholar : PubMed/NCBI
|
6
|
Basnet P and Skalko-Basnet N: Curcumin: An
anti-inflammatory molecule from a curry spice on the path to cancer
treatment. Molecules. 16:4567–4598. 2011. View Article : Google Scholar : PubMed/NCBI
|
7
|
Takeichi M: Morphogenetic roles of classic
cadherins. Curr Opin Cell Biol. 7:619–627. 1995. View Article : Google Scholar : PubMed/NCBI
|
8
|
Kotb AM, Hierholzer A and Kemler R:
Replacement of E-cadherin by N-cadherin in the mammary gland leads
to fibrocystic changes and tumor formation. Breast Cancer Res.
13:R1042011. View
Article : Google Scholar : PubMed/NCBI
|
9
|
Radice GL, Rayburn H, Matsunami H, Knudsen
KA, Takeichi M and Hynes RO: Developmental defects in mouse embryos
lacking N-cadherin. Dev Biol. 181:64–78. 1997. View Article : Google Scholar : PubMed/NCBI
|
10
|
Ozawa M, Baribault H and Kemler R: The
cytoplasmic domain of the cell adhesion molecule uvomorulin
associates with three independent proteins structurally related in
different species. EMBO J. 8:1711–1717. 1989.PubMed/NCBI
|
11
|
Hoschuetzky H, Aberle H and Kemler R:
Beta-catenin mediates the interaction of the cadherin-catenin
complex with epidermal growth factor receptor. J Cell Biol.
127:1375–1380. 1994. View Article : Google Scholar : PubMed/NCBI
|
12
|
Williams EJ, Furness J, Walsh FS and
Doherty P: Activation of the FGF receptor underlies neurite
outgrowth stimulated by L1, N-CAM, and N-cadherin. Neuron.
13:583–594. 1994. View Article : Google Scholar : PubMed/NCBI
|
13
|
Ilyas M and Tomlinson IP: The interactions
of APC, E-cadherin and beta-catenin in tumour development and
progression. J Pathol. 182:128–137. 1997. View Article : Google Scholar : PubMed/NCBI
|
14
|
Morin PJ, Sparks AB, Korinek V, Barker N,
Clevers H, Vogelstein B and Kinzler KW: Activation of
beta-catenin-Tcf signaling in colon cancer by mutations in
beta-catenin or APC. Science. 275:1787–1790. 1997. View Article : Google Scholar : PubMed/NCBI
|
15
|
Nieto MA: The snail superfamily of
zinc-finger transcription factors. Nat Rev Mol Cell Biol.
3:155–166. 2002. View
Article : Google Scholar : PubMed/NCBI
|
16
|
Barrallo-Gimeno A and Nieto MA: The Snail
genes as inducers of cell movement and survival: Implications in
development and cancer. Development. 132:3151–3161. 2005.
View Article : Google Scholar : PubMed/NCBI
|
17
|
Hemavathy K, Guru SC, Harris J, Chen JD
and Ip YT: Human Slug is a repressor that localizes to sites of
active transcription. Mol Cell Biol. 20:5087–5095. 2000. View Article : Google Scholar : PubMed/NCBI
|
18
|
Wu WS, Heinrichs S, Xu D, Garrison SP,
Zambetti GP, Adams JM and Look AT: Slug antagonizes p53-mediated
apoptosis of hematopoietic progenitors by repressing puma. Cell.
123:641–653. 2005. View Article : Google Scholar : PubMed/NCBI
|
19
|
O’Bryan JP, Frye RA, Cogswell PC, Neubauer
A, Kitch B, Prokop C, Espinosa R III, Le Beau MM, Earp HS and Liu
ET: axl, a transforming gene isolated from primary human myeloid
leukemia cells, encodes a novel receptor tyrosine kinase. Mol Cell
Biol. 11:5016–5031. 1991. View Article : Google Scholar
|
20
|
Bose R, Molina H, Patterson AS, Bitok JK,
Periaswamy B, Bader JS, Pandey A and Cole PA: Phosphoproteomic
analysis of Her2/neu signaling and inhibition. Proc Natl Acad Sci
USA. 103:9773–9778. 2006. View Article : Google Scholar : PubMed/NCBI
|
21
|
Hafizi S and Dahlbäck B: Gas6 and protein
S. Vitamin K-dependent ligands for the Axl receptor tyrosine kinase
subfamily. FEBS J. 273:5231–5244. 2006. View Article : Google Scholar : PubMed/NCBI
|
22
|
Hutterer M, Knyazev P, Abate A, Reschke M,
Maier H, Stefanova N, Knyazeva T, Barbieri V, Reindl M, Muigg A, et
al: Axl and growth arrest-specific gene 6 are frequently
overexpressed in human gliomas and predict poor prognosis in
patients with glioblastoma multiforme. Clin Cancer Res. 14:130–138.
2008. View Article : Google Scholar : PubMed/NCBI
|
23
|
Li Y, Ye X, Tan C, Hongo JA, Zha J, Liu J,
Kallop D, Ludlam MJ and Pei L: Axl as a potential therapeutic
target in cancer: Role of Axl in tumor growth, metastasis and
angiogenesis. Oncogene. 28:3442–3455. 2009. View Article : Google Scholar : PubMed/NCBI
|
24
|
Zhang YX, Knyazev PG, Cheburkin YV, Sharma
K, Knyazev YP, Orfi L, Szabadkai I, Daub H, Kéri G and Ullrich A:
AXL is a potential target for therapeutic intervention in breast
cancer progression. Cancer Res. 68:1905–1915. 2008. View Article : Google Scholar : PubMed/NCBI
|
25
|
Yang J, Mani SA, Donaher JL, Ramaswamy S,
Itzykson RA, Come C, Savagner P, Gitelman I, Richardson A and
Weinberg RA: Twist, a master regulator of morphogenesis, plays an
essential role in tumor metastasis. Cell. 117:927–939. 2004.
View Article : Google Scholar : PubMed/NCBI
|
26
|
Casas E, Kim J, Bendesky A, Ohno-Machado
L, Wolfe CJ and Yang J: Snail2 is an essential mediator of
Twist1-induced epithelial mesenchymal transition and metastasis.
Cancer Res. 71:245–254. 2011. View Article : Google Scholar : PubMed/NCBI
|
27
|
Eckert MA, Lwin TM, Chang AT, Kim J, Danis
E, Ohno-Machado L and Yang J: Twist1-induced invadopodia formation
promotes tumor metastasis. Cancer Cell. 19:372–386. 2011.
View Article : Google Scholar : PubMed/NCBI
|
28
|
Low-Marchelli JM, Ardi VC, Vizcarra EA,
van Rooijen N, Quigley JP and Yang J: Twist1 induces CCL2 and
recruits macrophages to promote angiogenesis. Cancer Res.
73:662–671. 2013. View Article : Google Scholar : PubMed/NCBI
|
29
|
Sommers CL, Skerker JM, Chrysogelos SA,
Bosseler M and Gelmann EP: Regulation of vimentin gene
transcription in human breast cancer cell lines. Cell Growth
Differ. 5:839–846. 1994.PubMed/NCBI
|
30
|
Manabe R, Oh-e N and Sekiguchi K:
Alternatively spliced EDA segment regulates fibronectin-dependent
cell cycle progression and mitogenic signal transduction. J Biol
Chem. 274:5919–5924. 1999. View Article : Google Scholar : PubMed/NCBI
|
31
|
Ohnishi T, Hiraga S, Izumoto S, Matsumura
H, Kanemura Y, Arita N and Hayakawa T: Role of
fibronectin-stimulated tumor cell migration in glioma invasion in
vivo: Clinical significance of fibronectin and fibronectin receptor
expressed in human glioma tissues. Clin Exp Metastasis. 16:729–741.
1998. View Article : Google Scholar
|
32
|
Sakai T, Johnson KJ, Murozono M, Sakai K,
Magnuson MA, Wieloch T, Cronberg T, Isshiki A, Erickson HP and
Fässler R: Plasma fibronectin supports neuronal survival and
reduces brain injury following transient focal cerebral ischemia
but is not essential for skin-wound healing and hemostasis. Nat
Med. 7:324–330. 2001. View
Article : Google Scholar : PubMed/NCBI
|
33
|
Moursi AM, Damsky CH, Lull J, Zimmerman D,
Doty SB, Aota S and Globus RK: Fibronectin regulates calvarial
osteoblast differentiation. J Cell Sci. 109:1369–1380.
1996.PubMed/NCBI
|
34
|
Johansson S, Svineng G, Wennerberg K,
Armulik A and Lohikangas L: Fibronectin-integrin interactions.
Front Biosci. 2:d126–d146. 1997. View
Article : Google Scholar : PubMed/NCBI
|
35
|
Sottile J and Hocking DC: Fibronectin
polymerization regulates the composition and stability of
extracellular matrix fibrils and cell-matrix adhesions. Mol Biol
Cell. 13:3546–3559. 2002. View Article : Google Scholar : PubMed/NCBI
|
36
|
Goerges AL and Nugent MA: pH regulates
vascular endothelial growth factor binding to fibronectin: A
mechanism for control of extracellular matrix storage and release.
J Biol Chem. 279:2307–2315. 2004. View Article : Google Scholar
|
37
|
Vannier C, Mock K, Brabletz T and Driever
W: Zeb1 regulates E-cadherin and Epcam (epithelial cell adhesion
molecule) expression to control cell behavior in early zebrafish
development. J Biol Chem. 288:18643–18659. 2013. View Article : Google Scholar : PubMed/NCBI
|
38
|
Verschueren K, Remacle JE, Collart C,
Kraft H, Baker BS, Tylzanowski P, Nelles L, Wuytens G, Su MT,
Bodmer R, et al: SIP1, a novel zinc finger/homeodomain repressor,
interacts with Smad proteins and binds to 5′-CACCT sequences in
candidate target genes. J Biol Chem. 274:20489–20498. 1999.
View Article : Google Scholar : PubMed/NCBI
|
39
|
Remacle JE, Kraft H, Lerchner W, Wuytens
G, Collart C, Verschueren K, Smith JC and Huylebroeck D: New mode
of DNA binding of multi-zinc finger transcription factors: deltaEF1
family members bind with two hands to two target sites. EMBO J.
18:5073–5084. 1999. View Article : Google Scholar : PubMed/NCBI
|
40
|
Francis NJ and Kingston RE: Mechanisms of
transcriptional memory. Nat Rev Mol Cell Biol. 2:409–421. 2001.
View Article : Google Scholar : PubMed/NCBI
|
41
|
Cao R, Wang L, Wang H, Xia L,
Erdjument-Bromage H, Tempst P, Jones RS and Zhang Y: Role of
histone H3 lysine 27 methylation in Polycomb-group silencing.
Science. 298:1039–1043. 2002. View Article : Google Scholar : PubMed/NCBI
|
42
|
Chang CJ and Hung MC: The role of EZH2 in
tumour progression. Br J Cancer. 106:243–247. 2012. View Article : Google Scholar :
|
43
|
Min J, Zaslavsky A, Fedele G, McLaughlin
SK, Reczek EE, De Raedt T, Guney I, Strochlic DE, Macconaill LE,
Beroukhim R, et al: An oncogene-tumor suppressor cascade drives
metastatic prostate cancer by coordinately activating Ras and
nuclear factor-kappaB. Nat Med. 16:286–294. 2010. View Article : Google Scholar : PubMed/NCBI
|
44
|
Bracken AP, Pasini D, Capra M, Prosperini
E, Colli E and Helin K: EZH2 is downstream of the pRB-E2F pathway,
essential for proliferation and amplified in cancer. EMBO J.
22:5323–5335. 2003. View Article : Google Scholar : PubMed/NCBI
|
45
|
Shi B, Liang J, Yang X, Wang Y, Zhao Y, Wu
H, Sun L, Zhang Y, Chen Y, Li R, et al: Integration of estrogen and
Wnt signaling circuits by the polycomb group protein EZH2 in breast
cancer cells. Mol Cell Biol. 27:5105–5119. 2007. View Article : Google Scholar : PubMed/NCBI
|
46
|
Xu K, Wu ZJ, Groner AC, He HH, Cai C, Lis
RT, Wu X, Stack EC, Loda M, Liu T, et al: EZH2 oncogenic activity
in castration-resistant prostate cancer cells is
Polycomb-independent. Science. 338:1465–1469. 2012. View Article : Google Scholar : PubMed/NCBI
|
47
|
Lee ST, Li Z, Wu Z, Aau M, Guan P,
Karuturi RK, Liou YC and Yu Q: Context-specific regulation of NF-κB
target gene expression by EZH2 in breast cancers. Mol Cell.
43:798–810. 2011. View Article : Google Scholar : PubMed/NCBI
|
48
|
Asangani IA, Ateeq B, Cao Q, Dodson L,
Pandhi M, Kunju LP, Mehra R, Lonigro RJ, Siddiqui J, Palanisamy N,
et al: Characterization of the EZH2-MMSET histone methyltransferase
regulatory axis in cancer. Mol Cell. 49:80–93. 2013. View Article : Google Scholar :
|
49
|
Takeda K and Akira S: STAT family of
transcription factors in cytokine-mediated biological responses.
Cytokine Growth Factor Rev. 11:199–207. 2000. View Article : Google Scholar : PubMed/NCBI
|
50
|
Zhou P, Jiang W, Weghorst CM and Weinstein
IB: Overexpression of cyclin D1 enhances gene amplification. Cancer
Res. 56:36–39. 1996.PubMed/NCBI
|
51
|
Arnold A and Papanikolaou A: Cyclin D1 in
breast cancer pathogenesis. J Clin Oncol. 23:4215–4224. 2005.
View Article : Google Scholar : PubMed/NCBI
|
52
|
Stylianou S, Clarke RB and Brennan K:
Aberrant activation of notch signaling in human breast cancer.
Cancer Res. 66:1517–1525. 2006. View Article : Google Scholar : PubMed/NCBI
|
53
|
Mungamuri SK, Yang X, Thor AD and
Somasundaram K: Survival signaling by Notch1: Mammalian target of
rapamycin (mTOR)-dependent inhibition of p53. Cancer Res.
66:4715–4724. 2006. View Article : Google Scholar : PubMed/NCBI
|
54
|
Lee CW, Simin K, Liu Q, Plescia J, Guha M,
Khan A, Hsieh CC and Altieri DC: A functional Notch-survivin gene
signature in basal breast cancer. Breast Cancer Res. 10:R972008.
View Article : Google Scholar : PubMed/NCBI
|
55
|
Dickson BC, Mulligan AM, Zhang H, et al:
High-level JAG1 mRNA and protein predict poor outcome in breast
cancer. Mod Pathol. 20:685–693. 2007. View Article : Google Scholar : PubMed/NCBI
|
56
|
Calaf GM and Hei TK: Establishment of a
radiation- and estrogen-induced breast cancer model.
Carcinogenesis. 21:769–776. 2000. View Article : Google Scholar : PubMed/NCBI
|
57
|
Jagtap S, Meganathan K, Wagh V, Winkler J,
Hescheler J and Sachinidis A: Chemoprotective mechanism of the
natural compounds, epigallocatechin-3-O-gallate, quercetin and
curcumin against cancer and cardiovascular diseases. Curr Med Chem.
16:1451–1462. 2009. View Article : Google Scholar : PubMed/NCBI
|
58
|
Calaf GM, Echiburú-Chau C, Wen G, Balajee
AS and Roy D: Effect of curcumin on irradiated and
estrogen-transformed human breast cell lines. Int J Oncol.
40:436–442. 2012.
|
59
|
Weissenberger J, Priester M, Bernreuther
C, Rakel S, Glatzel M, Seifert V and Kögel D: Dietary curcumin
attenuates glioma growth in a syngeneic mouse model by inhibition
of the JAK1,2/STAT3 signaling pathway. Clin Cancer Res.
16:5781–5795. 2010. View Article : Google Scholar : PubMed/NCBI
|
60
|
Calaf GM, Echiburú-Chau C, Roy D, Chai Y,
Wen G and Balajee AS: Protective role of curcumin in oxidative
stress of breast cells. Oncol Rep. 26:1029–1035. 2011.PubMed/NCBI
|
61
|
Tiwari N, Gheldof A, Tatari M and
Christofori G: EMT as the ultimate survival mechanism of cancer
cells. Semin Cancer Biol. 22:194–207. 2012. View Article : Google Scholar : PubMed/NCBI
|
62
|
Mulholland DJ, Kobayashi N, Ruscetti M,
Zhi A, Tran LM, Huang J, Gleave M and Wu H: Pten loss and RAS/MAPK
activation cooperate to promote EMT and metastasis initiated from
prostate cancer stem/progenitor cells. Cancer Res. 72:1878–1889.
2012. View Article : Google Scholar : PubMed/NCBI
|
63
|
Moreno-Bueno G, Portillo F and Cano A:
Transcriptional regulation of cell polarity in EMT and cancer.
Oncogene. 27:6958–6969. 2008. View Article : Google Scholar : PubMed/NCBI
|
64
|
Creighton CJ, Chang JC and Rosen JM:
Epithelial-mesenchymal transition (EMT) in tumor-initiating cells
and its clinical implications in breast cancer. J Mammary Gland
Biol Neoplasia. 15:253–260. 2010. View Article : Google Scholar : PubMed/NCBI
|
65
|
Vuoriluoto K, Haugen H, Kiviluoto S,
Mpindi JP, Nevo J, Gjerdrum C, Tiron C, Lorens JB and Ivaska J:
Vimentin regulates EMT induction by Slug and oncogenic H-Ras and
migration by governing Axl expression in breast cancer. Oncogene.
30:1436–1448. 2011. View Article : Google Scholar
|
66
|
Hardy KM, Booth BW, Hendrix MJ, Salomon DS
and Strizzi L: ErbB/EGF signaling and EMT in mammary development
and breast cancer. J Mammary Gland Biol Neoplasia. 15:191–199.
2010. View Article : Google Scholar : PubMed/NCBI
|
67
|
Vincan E and Barker N: The upstream
components of the Wnt signalling pathway in the dynamic EMT and MET
associated with colorectal cancer progression. Clin Exp Metastasis.
25:657–663. 2008. View Article : Google Scholar : PubMed/NCBI
|
68
|
Javle MM, Gibbs JF, Iwata KK, Pak Y,
Rutledge P, Yu J, Black JD, Tan D and Khoury T:
Epithelial-mesenchymal transition (EMT) and activated extracellular
signal-regulated kinase (p-Erk) in surgically resected pancreatic
cancer. Ann Surg Oncol. 14:3527–3533. 2007. View Article : Google Scholar : PubMed/NCBI
|
69
|
Yin T, Wang C, Liu T, Zhao G and Zhou F:
Implication of EMT induced by TGF-beta1 in pancreatic cancer. J
Huazhong Univ Sci Technolog Med Sci. 26:700–702. 2006. View Article : Google Scholar
|
70
|
Pinho SS, Oliveira P, Cabral J, Carvalho
S, Huntsman D, Gärtner F, Seruca R, Reis CA and Oliveira C: Loss
and recovery of Mgat3 and GnT-III Mediated E-cadherin
N-glycosylation is a mechanism involved in
epithelial-mesenchymal-epithelial transitions. PLoS One.
7:e331912012. View Article : Google Scholar : PubMed/NCBI
|
71
|
Ivaska J: Vimentin: Central hub in EMT
induction? Small GTPases. 2:51–53. 2011. View Article : Google Scholar : PubMed/NCBI
|
72
|
Wu Y and Zhou BP: Snail: More than EMT.
Cell Adhes Migr. 4:199–203. 2010. View Article : Google Scholar
|
73
|
Fendrich V, Waldmann J, Feldmann G,
Schlosser K, König A, Ramaswamy A, Bartsch DK and Karakas E: Unique
expression pattern of the EMT markers Snail, Twist and E-cadherin
in benign and malignant parathyroid neoplasia. Eur J Endocrinol.
160:695–703. 2009. View Article : Google Scholar : PubMed/NCBI
|
74
|
Mukhopadhyay A, Banerjee S, Stafford LJ,
Xia C, Liu M and Aggarwal BB: Curcumin-induced suppression of cell
proliferation correlates with down-regulation of cyclin D1
expression and CDK4-mediated retinoblastoma protein
phosphorylation. Oncogene. 21:8852–8861. 2002. View Article : Google Scholar : PubMed/NCBI
|
75
|
Kumaravel M, Sankar P and Rukkumani R:
Antiproliferative effect of an analog of curcumin
bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione in human breast
cancer cells. Eur Rev Med Pharmacol Sci. 16:1900–1907.
2012.PubMed/NCBI
|
76
|
Lin SS, Lai KC, Hsu SC, Yang JS, Kuo CL,
Lin JP, Ma YS, Wu CC and Chung JG: Curcumin inhibits the migration
and invasion of human A549 lung cancer cells through the inhibition
of matrix metalloproteinase-2 and -9 and vascular endothelial
growth factor (VEGF). Cancer Lett. 285:127–133. 2009. View Article : Google Scholar : PubMed/NCBI
|
77
|
Huang T, Chen Z and Fang L: Curcumin
inhibits LPS-induced EMT through downregulation of NF-κB-Snail
signaling in breast cancer cells. Oncol Rep. 29:117–124. 2013.
|