Journal Articles
Review
Neutrophils in cancer development and progression: Roles, mechanisms, and implications (Review)
Xu Zhang, Wen Zhang, Xiao Yuan, Min Fu, Hui Qian, Wenrong Xu
Pages: 857-867 Published online on: 07 July 2016
Article
Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors
Makoto Nakakido, Kenji Tamura, Suyoun Chung, Koji Ueda, Risa Fujii, Kazuma Kiyotani, Yusuke Nakamura
Pages: 868-876 Published online on: 06 July 2016
Article
Actin bundling by dynamin 2 and cortactin is implicated in cell migration by stabilizing filopodia in human non-small cell lung carcinoma cells
Hiroshi Yamada, Tetsuya Takeda, Hiroyuki Michiue, Tadashi Abe, Kohji Takei
Pages: 877-886 Published online on: 30 June 2016
Article
Enhanced expression of semaphorin 3E is involved in the gastric cancer development
Ryuhei Maejima, Keiichi Tamai, Takeharu Shiroki, Misa Yokoyama, Rie Shibuya, Mao Nakamura, Kazunori Yamaguchi, Makoto Abue, Tomoyuki Oikawa, Tetsuya Noguchi, Koh Miura, Tsuneaki Fujiya, Ikuro Sato, Katsunori Iijima, Tooru Shimosegawa, Nobuyuki Tanaka, Kennichi Satoh
Pages: 887-894 Published online on: 30 June 2016
Article
Lipoprotein(a) and vitamin C impair development of breast cancer tumors in Lp(a)+; Gulo-/- mice
John Cha, M. Waheed Roomi, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 895-902 Published online on: 01 July 2016
Article
Overexpression of KH-type splicing regulatory protein regulates proliferation, migration, and implantation ability of osteosarcoma
Dumnoensun Pruksakorn, Pimpisa Teeyakasem, Jeerawan Klangjorhor, Parunya Chaiyawat, Jongkolnee Settakorn, Penchatr Diskul-Na-Ayudthaya, Daranee Chokchaichamnankit, Peraphan Pothacharoen, Chantragan Srisomsap
Pages: 903-912 Published online on: 04 July 2016
Article
Protein signatures as potential surrogate biomarkers for stratification and prediction of treatment response in chronic myeloid leukemia patients
Ayodele A. Alaiya, Mahmoud Aljurf, Zakia Shinwari, Fahad Almohareb, Hafiz Malhan, Hazzaa Alzahrani, Tarek Owaidah, Jonathan Fox, Fahad Alsharif, Said Y. Mohamed, Walid Rasheed, Ghuzayel Aldawsari, Amr Hanbali, Syed Osman Ahmed, Naeem Chaudhri
Pages: 913-933 Published online on: 07 July 2016
Article
Neuromedin B receptor antagonism inhibits migration, invasion, and epithelial-mesenchymal transition of breast cancer cells
Hyun-Joo Park, Mi-Kyoung Kim, Kyu-Sil Choi, Joo-Won Jeong, Soo-Kyung Bae, Hyung Joon Kim, Moon-Kyoung Bae
Pages: 934-942 Published online on: 30 June 2016
Article
Long non-coding RNA HOTAIR modulates HLA-G expression by absorbing miR-148a in human cervical cancer
Jinbao Sun, Haipeng Chu, Jianghai Ji, Gaoxiang Huo, Qinglei Song, Xue Zhang
Pages: 943-952 Published online on: 30 June 2016
Article
GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax
Kateřina Vlčková, Jiri Réda, Lubica Ondrušová, Mohammad Krayem, Ghanem Ghanem, Jiri Vachtenheim
Pages: 953-960 Published online on: 01 July 2016
Article
SPECT imaging of neuropilin receptor type-1 expression with 131I-labeled monoclonal antibody
Xiaofeng Dou, Jianghua Yan, Yafei Zhang, Peng Liu, Yizhen Jiang, Sha Lv, Fanwei Zeng, Xiaoli Chen, Shengyu Wang, Haipeng Zhang, Hua Wu, Hong Zhang, Lin Ouyang, Xinhui Su
Pages: 961-970 Published online on: 16 June 2016
Article
Sustainable inflammation transforms hepatic cells by causing oxidative stress injury and potential epithelial-mesenchymal transition
Kun Lu, Guoyan Liu, Ling Yang, Fan Liu, Libin Gao, Jingxian Shi, Xiaoling Deng, Qifu Li, Donghui Xu, Songlin Shi
Pages: 971-980 Published online on: 16 June 2016
Article
Lentivirus-mediated downregulation of MAT2B inhibits cell proliferation and induces apoptosis in melanoma
Yu Lei, Bo Zhang, Yaohua Zhang, Yuan Zhao, Jingying Sun, Xuejun Zhang, Sen Yang
Pages: 981-990 Published online on: 05 July 2016
Article
Association between cancer stem cell-like properties and epithelial-to-mesenchymal transition in primary and secondary cancer cells
Wonbong Lim, Hye-Eun Kim, Young Kim, Risu Na, Xiaojie Li, Sangmi Jeon, Hongran Choi, Okjoon Kim
Pages: 991-1000 Published online on: 16 June 2016
Article
SPOP promotes tumor progression via activation of β-catenin/TCF4 complex in clear cell renal cell carcinoma
Wencai Zhao, Jiancheng Zhou, Zhuo Deng, Yang Gao, Yongyi Cheng
Pages: 1001-1008 Published online on: 06 July 2016
Article
Baicalein induces apoptosis via ROS-dependent activation of caspases in human bladder cancer 5637 cells
Eun-Ok Choi, Cheol Park, Hye-Jin Hwang, Su Hyun Hong, Gi-Young Kim, Eun-Ju Cho, Wun-Jae Kim, Yung Hyun Choi
Pages: 1009-1018 Published online on: 06 July 2016
Article
Curcumin inhibits invasive capabilities through epithelial mesenchymal transition in breast cancer cell lines
Marcela Gallardo, Gloria M. Calaf
Pages: 1019-1027 Published online on: 04 July 2016
Article
Silencing Aurora-A with siRNA inhibits cell proliferation in human lung adenocarcinoma cells
Ning Zhong, Shunbin Shi, Hongzhen Wang, Guangzhou Wu, Yunliang Wang, Qiang Ma, Hongwei Wang, Yuanhua Liu, Jinzhi Wang
Pages: 1028-1038 Published online on: 05 July 2016
Article
The novel mTORC1/2 dual inhibitor INK128 enhances radiosensitivity of breast cancer cell line MCF-7
Zhi-Gang Liu, Jiao Tang, Zhenghu Chen, Huiyuan Zhang, Hui Wang, Jianhua Yang, Hong Zhang
Pages: 1039-1045 Published online on: 05 July 2016
Article
TSC22D2 interacts with PKM2 and inhibits cell growth in colorectal cancer
Fang Liang, Qiao Li, Xiayu Li, Zheng Li, Zhaojian Gong, Hao Deng, Bo Xiang, Ming Zhou, Xiaoling Li, Guiyuan Li, Zhaoyang Zeng, Wei Xiong
Pages: 1046-1056 Published online on: 04 July 2016
Article
Heterogeneous expression of zinc-finger E-box-binding homeobox 1 plays a pivotal role in metastasis via regulation of miR-200c in epithelial-mesenchymal transition
Yuta Muto, Koichi Suzuki, Takaharu Kato, Shingo Tsujinaka, Kosuke Ichida, Yuji Takayama, Taro Fukui, Nao Kakizawa, Fumiaki Watanabe, Masaaki Saito, Kazushige Futsuhara, Hiroshi Noda, Yasuyuki Miyakura, Fumio Konishi, Toshiki Rikiyama
Pages: 1057-1067 Published online on: 17 June 2016
Article
MicroRNA-224 aggrevates tumor growth and progression by targeting mTOR in gastric cancer
Ying Zhang, Chang-Feng Li, Lian-Jun Ma, Meng Ding, Bin Zhang
Pages: 1068-1080 Published online on: 16 June 2016
Article
A 3-dimensional DTI MRI-based model of GBM growth and response to radiation therapy
Leith Hathout, Vishal Patel, Patrick Wen
Pages: 1081-1087 Published online on: 01 July 2016
Article
Torilis japonica extract-generated intracellular ROS induces apoptosis by reducing the mitochondrial membrane potential via regulation of the AMPK-p38 MAPK signaling pathway in HCT116 colon cancer
Guen Tae Kim, Se Hee Lee, Young Min Kim
Pages: 1088-1098 Published online on: 16 June 2016
Article
Immunological effects of the anti-programmed death-1 antibody on human peripheral blood mononuclear cells
Yasuto Akiyama, Chizu Nonomura, Ryota Kondou, Haruo Miyata, Tadashi Ashizawa, Chie Maeda, Koichi Mitsuya, Nakamasa Hayashi, Yoko Nakasu, Ken Yamaguchi
Pages: 1099-1107 Published online on: 29 June 2016
Article
Weighted gene co-expression network analysis of colorectal cancer liver metastasis genome sequencing data and screening of anti-metastasis drugs
Bo Gao, Qin Shao, Hani Choudhry, Victoria Marcus, Kung Dong, Jiannis Ragoussis, Zu-Hua Gao
Pages: 1108-1118 Published online on: 30 June 2016
Article
The tumor-suppressive microRNA-23b/27b cluster regulates the MET oncogene in oral squamous cell carcinoma
Ichiro Fukumoto, Keiichi Koshizuka, Toyoyuki Hanazawa, Naoko Kikkawa, Ryosuke Matsushita, Akira Kurozumi, Mayuko Kato, Atsushi Okato, Yoshitaka Okamoto, Naohiko Seki
Pages: 1119-1129 Published online on: 04 July 2016
Article
Anti-EGFR immunonanoparticles containing IL12 and salmosin genes for targeted cancer gene therapy
Jung Seok Kim, Seong Jae Kang, Hwa Yeon Jeong, Min Woo Kim, Sang Il Park, Yeon Kyung Lee, Hong Sung Kim, Keun Sik Kim, Yong Serk Park
Pages: 1130-1138 Published online on: 07 July 2016
Article
The inhibition of cell proliferation and induction of apoptosis in pancreatic ductal adenocarcinoma cells by verrucarin A, a macrocyclic trichothecene, is associated with the inhibition of Akt/NF-кB/mTOR prosurvival signaling
Dorrah Deeb, Xiaohua Gao, Yongbo Liu, Yiguan Zhang, Jiajiu Shaw, Frederick A. Valeriote, Subhash C. Gautam
Pages: 1139-1147 Published online on: 29 June 2016
Article
Eupatilin inhibits EGF-induced JB6 cell transformation by targeting PI3K
Feng Li, Ya Tao, Yan Qiao, Ke Li, Yanan Jiang, Chang Cao, Shuxin Ren, Xiaobin Chang, Xiaona Wang, Yanhong Wang, Yifei Xie, Ziming Dong, Jimin Zhao, Kangdong Liu
Pages: 1148-1154 Published online on: 04 July 2016
Article
MicroRNA-195 targets VEGFR2 and has a tumor suppressive role in ACHN cells via PI3K/Akt and Raf/MEK/ERK signaling pathways
Pengcheng Sun, Lu Wang, Yunhan Lu, Yuwei Liu, Lechen Li, Luyao Yin, Cheng Zhang, Weiming Zhao, Baozhong Shen, Wanhai Xu
Pages: 1155-1163 Published online on: 06 July 2016
Article
Targeting the PI3K/AKT/mTOR pathway overcomes the stimulating effect of dabrafenib on the invasive behavior of melanoma cells with acquired resistance to the BRAF inhibitor
Simona Caporali, Ester Alvino, Pedro Miguel Lacal, Lauretta Levati, Giorgio Giurato, Domenico Memoli, Elisabetta Caprini, Gian Carlo Antonini Cappellini, Stefania D'Atri
Pages: 1164-1174 Published online on: 30 June 2016
Article
FHIT promoter methylation status, low protein and high mRNA levels in patients with non-small cell lung cancer
Karolina H. Czarnecka, Monika Migdalska-Sęk, Daria Domańska, Dorota Pastuszak-Lewandoska, Agata Dutkowska, Jacek Kordiak, Ewa Nawrot, Justyna Kiszałkiewicz, Adam Antczak, Ewa Brzeziańska-Lasota
Pages: 1175-1184 Published online on: 06 July 2016
Article
Influence of molecular design on biodistribution and targeting properties of an Affibody-fused HER2-recognising anticancer toxin
Mohamed Altai, Hao Liu, Anna Orlova, Vladimir Tolmachev, Torbjörn Gräslund
Pages: 1185-1194 Published online on: 06 July 2016
Article
Protein arginine methyltransferase 5 is associated with malignant phenotype and peritoneal metastasis in gastric cancer
Mitsuro Kanda, Dai Shimizu, Tsutomu Fujii, Haruyoshi Tanaka, Masahiro Shibata, Naoki Iwata, Masamichi Hayashi, Daisuke Kobayashi, Chie Tanaka, Suguru Yamada, Goro Nakayama, Hiroyuki Sugimoto, Masahiko Koike, Michitaka Fujiwara, Yasuhiro Kodera
Pages: 1195-1202 Published online on: 17 June 2016
Article
Genistein targets the cancerous inhibitor of PP2A to induce growth inhibition and apoptosis in breast cancer cells
Qingxia Zhao, Ming Zhao, Amanda B. Parris, Ying Xing, Xiaohe Yang
Pages: 1203-1210 Published online on: 30 June 2016
Article
Inhibition of pregnane X receptor pathway contributes to the cell growth inhibition and apoptosis of anticancer agents in ovarian cancer cells
Hisashi Masuyama, Keiichiro Nakamura, Etsuko Nobumoto, Yuji Hiramatsu
Pages: 1211-1220 Published online on: 06 July 2016
Article
An azaspirane derivative suppresses growth and induces apoptosis of ER-positive and ER-negative breast cancer cells through the modulation of JAK2/STAT3 signaling pathway
Nurfarhanah Bte Syed Sulaiman, Chakrabhavi Dhananjaya Mohan, Salundi Basappa, Vijay Pandey, Shobith Rangappa, Hanumantharayappa Bharathkumar, Alan Prem Kumar, Peter E. Lobie, Kanchugarakoppal S. Rangappa
Pages: 1221-1229 Published online on: 06 July 2016
Article
Suppression of MMP-9 and FAK expression by pomolic acid via blocking of NF-κB/ERK/mTOR signaling pathways in growth factor-stimulated human breast cancer cells
Ji-Hyun Park, Yoon Young Cho, Seong Woo Yoon, Byoungduck Park
Pages: 1230-1240 Published online on: 29 June 2016
Article
5-Azacytidine regulates matrix metalloproteinase-9 expression, and the migration and invasion of human fibrosarcoma HT1080 cells via PI3-kinase and ERK1/2 pathways
Seon-Mi Yu, Song Ja Kim
Pages: 1241-1247 Published online on: 06 July 2016
Article
Induction of TTF-1 or PAX-8 expression on proliferation and tumorigenicity in thyroid carcinomas
Célia Dupain, Hafiz M. Ali, Tarik Ait Mouhoub, Giorgia Urbinati, Liliane Massaad-Massade
Pages: 1248-1258 Published online on: 07 July 2016
Correction
[Corrigendum] Preventive effect of caffeine and curcumin on hepato-carcinogenesis in diethylnitrosamine-induced rats
Yuki Fujise, Jun-Ichi Okano, Takakazu Nagahara, Ryo Abe, Ryu Imamoto, Yoshikazu Murawaki
Pages: 1259-1259 Published online on: 15 June 2016
Correction