Open Access

Magnetic resonance imaging - ultrasound fusion targeted biopsy outperforms standard approaches in detecting prostate cancer: A meta-analysis

  • Authors:
    • Xuping Jiang
    • Jiayi Zhang
    • Jingyuan Tang
    • Zhen Xu
    • Wei Zhang
    • Qing Zhang
    • Hongqian Guo
    • Weimin Zhou
  • View Affiliations

  • Published online on: May 20, 2016     https://doi.org/10.3892/mco.2016.906
  • Pages: 301-309
  • Copyright: © Jiang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The aim of the present study was to determine whether magnetic resonance imaging ‑ ultrasound (MRI‑US) fusion prostate biopsy is superior to systematic biopsy for making a definitive diagnosis of prostate cancer. The two strategies were also compared regarding their ability to detect clinically significant and insignificant prostate cancer. A literature search was conducted through the PubMed, EMBASE and China National Knowledge Infrastructure databases using appropriate search terms. A total of 3,415 cases from 21 studies were included in the present meta‑analysis. Data were expressed as relative risk (RR) and 95% confidence interval. The results revealed that MRI‑US fusion biopsy achieved a higher rate of overall prostate cancer detection compared with systematic biopsy (RR=1.09; P=0.047). Moreover, MRI‑US fusion biopsy detected more clinically significant cancers compared with systematic biopsy (RR=1.22; P<0.01). It is therefore recommended that multi-parametric MRI-US is performed in men suspected of having prostate cancer to optimize the detection of clinically significant disease, while reducing the burden of biopsies.
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August-2016
Volume 5 Issue 2

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Spandidos Publications style
Jiang X, Zhang J, Tang J, Xu Z, Zhang W, Zhang Q, Guo H and Zhou W: Magnetic resonance imaging - ultrasound fusion targeted biopsy outperforms standard approaches in detecting prostate cancer: A meta-analysis. Mol Clin Oncol 5: 301-309, 2016.
APA
Jiang, X., Zhang, J., Tang, J., Xu, Z., Zhang, W., Zhang, Q. ... Zhou, W. (2016). Magnetic resonance imaging - ultrasound fusion targeted biopsy outperforms standard approaches in detecting prostate cancer: A meta-analysis. Molecular and Clinical Oncology, 5, 301-309. https://doi.org/10.3892/mco.2016.906
MLA
Jiang, X., Zhang, J., Tang, J., Xu, Z., Zhang, W., Zhang, Q., Guo, H., Zhou, W."Magnetic resonance imaging - ultrasound fusion targeted biopsy outperforms standard approaches in detecting prostate cancer: A meta-analysis". Molecular and Clinical Oncology 5.2 (2016): 301-309.
Chicago
Jiang, X., Zhang, J., Tang, J., Xu, Z., Zhang, W., Zhang, Q., Guo, H., Zhou, W."Magnetic resonance imaging - ultrasound fusion targeted biopsy outperforms standard approaches in detecting prostate cancer: A meta-analysis". Molecular and Clinical Oncology 5, no. 2 (2016): 301-309. https://doi.org/10.3892/mco.2016.906