Open Access

Prevalence of ACA variations: A systematic review and meta‑analysis

  • Authors:
    • George Fotakopoulos
    • Alexandros G. Brotis
    • Ourania Fotakopoulou
    • Charalampos Gatos
    • Konstantinos Mantzarlis
    • Vasiliki Epameinondas Georgakopoulou
    • Pagona Sklapani
    • Nikolaos Trakas
    • Kostas N. Fountas
  • View Affiliations

  • Published online on: July 15, 2024     https://doi.org/10.3892/mi.2024.178
  • Article Number: 54
  • Copyright : © Fotakopoulos et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

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Abstract

The anterior cerebral artery (ACA) and its divisions enclose symptomatically critical and supplementary differentiations. Anatomical variations of the distal ACA that are irregularly detected can be separated into three major groups, namely, azygos, bihemispheric and median ACA variations. The present study performed a systematic review and meta‑analysis. The PICOS criteria and electronic databases, namely the Cochrane Library, PubMed (until December, 2023), Embase (until December, 2023) and MEDLINE (until December, 2023) were used to identify 48 articles to fulfill the eligible criteria. As a limited number of studies exist on the prevalence of ACA anatomical variations, the present meta‑analysis aimed to determine the precise incidence of these variants. In addition, with the comparative description between cadaveric (autopsy) and imaging cases, more accurate results were extract from the prevalence presentation of the distal ACA variants. On the whole, no statistically significant differences were found between autopsy and imaging studies. 
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September-October 2024
Volume 4 Issue 5

Print ISSN: 2754-3242
Online ISSN:2754-1304

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Spandidos Publications style
Fotakopoulos G, Brotis AG, Fotakopoulou O, Gatos C, Mantzarlis K, Georgakopoulou VE, Sklapani P, Trakas N and Fountas KN: Prevalence of ACA variations: A systematic review and meta‑analysis. Med Int 4: 54, 2024.
APA
Fotakopoulos, G., Brotis, A.G., Fotakopoulou, O., Gatos, C., Mantzarlis, K., Georgakopoulou, V.E. ... Fountas, K.N. (2024). Prevalence of ACA variations: A systematic review and meta‑analysis. Medicine International, 4, 54. https://doi.org/10.3892/mi.2024.178
MLA
Fotakopoulos, G., Brotis, A. G., Fotakopoulou, O., Gatos, C., Mantzarlis, K., Georgakopoulou, V. E., Sklapani, P., Trakas, N., Fountas, K. N."Prevalence of ACA variations: A systematic review and meta‑analysis". Medicine International 4.5 (2024): 54.
Chicago
Fotakopoulos, G., Brotis, A. G., Fotakopoulou, O., Gatos, C., Mantzarlis, K., Georgakopoulou, V. E., Sklapani, P., Trakas, N., Fountas, K. N."Prevalence of ACA variations: A systematic review and meta‑analysis". Medicine International 4, no. 5 (2024): 54. https://doi.org/10.3892/mi.2024.178