1
|
Frye M and Watt FM: The RNA
methyltransferase Misu (NSun2) mediates Myc-induced proliferation
and is upregulated in tumors. Curr Biol. 16:971–981. 2006.
View Article : Google Scholar : PubMed/NCBI
|
2
|
Yi J, Gao R, Chen Y, Yang Z, Han P, Zhang
H, Dou Y, Liu W, Wang W, Du G, et al: Overexpression of NSUN2 by
DNA hypomethylation is associated with metastatic progression in
human breast cancer. Oncotarget. 8:20751–20765. 2017. View Article : Google Scholar : PubMed/NCBI
|
3
|
Hussain S, Tuorto F, Menon S, Blanco S,
Cox C, Flores JV, Watt S, Kudo NR, Lyko F, Frye M, et al: The mouse
cytosine-5 RNA Methyltransferase NSun2 Is a component of the
chromatoid body and required for testis differentiation. Mol Cell
Biol. 33:15612013. View Article : Google Scholar : PubMed/NCBI
|
4
|
Khan MA, Rafiq MA, Noor A, Hussain S,
Flores JV, Rupp V, Vincent AK, Malli R, Ali G, Khan FS, et al:
Mutation in NSUN2, which encodes an RNA methyltransferase, causes
autosomal-recessive intellectual disability. Am J Hum Genet.
90:856–863. 2012. View Article : Google Scholar : PubMed/NCBI
|
5
|
Okamoto M, Hirata S, Sato S, Koga S, Fujii
M, Qi G, Ogawa I, Takata T, Shimamoto F and Tatsuka M: Frequent
increased gene copy number and high protein expression of tRNA
(cytosine-5-)-methyltransferase (NSUN2) in human cancers. DNA Cell
Biol. 31:660–671. 2012. View Article : Google Scholar : PubMed/NCBI
|
6
|
Zhang X, Liu Z, Yi J, Tang H, Xing J, Yu
M, Tong T, Shang Y, Gorospe M and Wang W: The tRNA
methyltransferase NSun2 stabilizes p16INK(4) mRNA by methylating
the 3′-untranslated region of p16. Nat Commun. 3:7122012.
View Article : Google Scholar : PubMed/NCBI
|
7
|
Xing J, Yi J, Cai X, Tang H, Liu Z, Zhang
X, Martindale JL, Yang X, Jiang B, Gorospe M and Wang W: NSun2
promotes cell growth via elevating cyclin-dependent kinase 1
translation. Mol Cell Biol. 35:4043–4052. 2015. View Article : Google Scholar : PubMed/NCBI
|
8
|
Li Q, Li X, Tang H, Jiang B, Dou Y,
Gorospe M and Wang W: NSUN2-mediated m5C methylation and
METTL3/METTL14-mediated m6A methylation cooperatively enhance p21
Translation. J Cell Biochem. 118:2587–2598. 2017. View Article : Google Scholar : PubMed/NCBI
|
9
|
Hussain S, Sajini AA, Blanco S, Dietmann
S, Lombard P, Sugimoto Y, Paramor M, Gleeson JG, Odom DT, Ule J and
Frye M: NSun2-mediated cytosine-5 methylation of vault noncoding
RNA determines its processing into regulatory small RNAs. Cell Rep.
4:255–261. 2013. View Article : Google Scholar : PubMed/NCBI
|
10
|
Yuan S, Tang H, Xing J, Fan X, Cai X, Li
Q, Han P, Luo Y, Zhang Z, Jiang B, et al: Methylation by NSun2
represses the levels and function of microRNA 125b. Mol Cell Biol.
34:3630–3641. 2014. View Article : Google Scholar : PubMed/NCBI
|
11
|
Li L and Chang HY: Physiological roles of
long noncoding RNAs: Insight from knockout mice. Trends Cell Biol.
24:594–602. 2014. View Article : Google Scholar : PubMed/NCBI
|
12
|
Deng K, Guo X, Wang H and Xia J: The
lncRNA-MYC regulatory network in cancer. Tumour Biol. 35:9497–9503.
2014. View Article : Google Scholar : PubMed/NCBI
|
13
|
Ma C, Nong K, Zhu H, Wang W, Huang X, Yuan
Z and Ai K: H19 promotes pancreatic cancer metastasis by
derepressing let-7's suppression on its target HMGA2-mediated EMT.
Tumour Biol. 35:9163–9169. 2014. View Article : Google Scholar : PubMed/NCBI
|
14
|
Liu Y, Han X, Yuan J, Geng T, Chen S, Hu
X, Cui IH and Cui H: Biallelic insertion of a transcriptional
terminator via the CRISPR/Cas9 system efficiently silences
expression of protein-coding and non-coding RNA genes. J Biol Chem.
292:5624–5633. 2017. View Article : Google Scholar : PubMed/NCBI
|
15
|
Bolger AM, Lohse M and Usadel B:
Trimmomatic: A flexible trimmer for Illumina sequence data.
Bioinformatics. 30:2114–2120. 2014. View Article : Google Scholar : PubMed/NCBI
|
16
|
Kim D, Langmead B and Salzberg SL: HISAT:
A fast spliced aligner with low memory requirements. Nat Methods.
12:357–360. 2015. View Article : Google Scholar : PubMed/NCBI
|
17
|
Pertea M, Pertea GM, Antonescu CM, Chang
TC, Mendell JT and Salzberg SL: StringTie enables improved
reconstruction of a transcriptome from RNA-seq reads. Nat
Biotechnol. 33:290–295. 2015. View
Article : Google Scholar : PubMed/NCBI
|
18
|
Sahraeian SME, Mohiyuddin M, Sebra R,
Tilgner H, Afshar PT, Au KF, Bani Asadi N, Gerstein MB, Wong WH,
Snyder MP, et al: Gaining comprehensive biological insight into the
transcriptome by performing a broad-spectrum RNA-seq analysis. Nat
Commun. 8:592017. View Article : Google Scholar : PubMed/NCBI
|
19
|
Benjamini Y and Hochberg Y: Controlling
the false discovery rate: A practical and powerful approach to
multiple testing. J Royal Statistical Soc. 57:289–300. 1995.
|
20
|
Lobo I: Basic local alignment search tool
(BLAST). J Mol Biol. 215:403–410. 2012.
|
21
|
Tafer H and Hofacker IL: RNAplex: A fast
tool for RNA-RNA interaction search. Bioinformatics. 24:2657–2663.
2008. View Article : Google Scholar : PubMed/NCBI
|
22
|
Boyle EI, Weng S, Gollub J, Jin H,
Botstein D, Cherry JM and Sherlock G: GO: TermFinder-open source
software for accessing Gene Ontology information and finding
significantly enriched gene ontology terms associated with a list
of genes. Bioinformatics. 20:3710–3715. 2004. View Article : Google Scholar : PubMed/NCBI
|
23
|
Kanehisa M: The KEGG database. Novartis
Found Symp. 247:101–103, 119–128, 244–252.. 2002.
|
24
|
Kohl M, Wiese S and Warscheid B:
Cytoscape: Software for visualization and analysis of biological
networks. Met Mol Biol. 696:291–303. 2011. View Article : Google Scholar
|
25
|
Schmittgen TD: Analysis of relative gene
expression data using real-time quantitative PCR and the 2(-Delta
Delta C(T)) method. Methods. 25:402–408. 2001. View Article : Google Scholar : PubMed/NCBI
|
26
|
Wang P, Fu H, Cui J and Chen X:
Differential lncRNA-mRNA co-expression network analysis revealing
the potential regulatory roles of lncRNAs in myocardial infarction.
Mol Med Rep. 13:11952016. View Article : Google Scholar : PubMed/NCBI
|
27
|
Zhang Y, Yang H, Han L, Li F, Zhang T,
Pang J, Feng X, Ren C, Mao S and Wang F: Long noncoding RNA
expression profile changes associated with dietary energy in the
sheep testis during sexual maturation. Sci Rep. 7:51802017.
View Article : Google Scholar : PubMed/NCBI
|
28
|
Tuorto F, Liebers R, Musch T, Schaefer M,
Hofmann S, Kellner S, Frye M, Helm M, Stoecklin G and Lyko F: RNA
cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and
protein synthesis. Nat Struct Mol Biol. 19:900–905. 2012.
View Article : Google Scholar : PubMed/NCBI
|
29
|
Yang X, Yang Y, Sun BF, Chen YS, Xu JW,
Lai WY, Li A, Wang X, Bhattarai DP, Xiao W, et al: 5-methylcytosine
promotes mRNA export-NSUN2 as the methyltransferase and ALYREF as
an m5C reader. Cell Res. 27:606–625. 2017. View Article : Google Scholar : PubMed/NCBI
|
30
|
Vance KW and Ponting CP: Transcriptional
regulatory functions of nuclear long noncoding RNAs. Trends Genet.
30:348–355. 2014. View Article : Google Scholar : PubMed/NCBI
|
31
|
Nguyenngoc KV, Cheung KJ, Brenot A, Shamir
ER, Gray RS, Hines WC, Yaswen P, Werb Z and Ewald AJ: ECM
microenvironment regulates collective migration and local
dissemination in normal and malignant mammary epithelium. Proc Natl
Acad Sci USA. 109:2595–2604. 2012. View Article : Google Scholar : PubMed/NCBI
|
32
|
Armstrong SJ, Wiberg M, Terenghi G and
Kingham PJ: ECM molecules mediate both Schwann cell proliferation
and activation to enhance neurite outgrowth. Tissue Eng.
13:2863–2870. 2007. View Article : Google Scholar : PubMed/NCBI
|
33
|
Cheresh DA and Stupack DG: Regulation of
angiogenesis: Apoptotic cues from the ECM. Oncogene. 27:6285–6298.
2008. View Article : Google Scholar : PubMed/NCBI
|
34
|
Steelman LS, Chappell WH, Abrams SL, Kempf
RC, Long J, Laidler P, Mijatovic S, Maksimovic-Ivanic D, Stivala F,
Mazzarino MC, et al: Roles of the Raf/MEK/ERK and
PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity
to therapy-implications for cancer and aging. Aging (Albany NY).
3:1922011. View Article : Google Scholar : PubMed/NCBI
|
35
|
Peltier J, O'Neill A and Schaffer DV:
PI3K/Akt and CREB regulate adult neural hippocampal progenitor
proliferation and differentiation. Dev Neurobiol. 67:1348–1361.
2007. View Article : Google Scholar : PubMed/NCBI
|
36
|
Zheng H, Fu G, Dai T and Huang H:
Migration of endothelial progenitor cells mediated by stromal
cell-derived factor-1alpha/CXCR4 via PI3K/Akt/eNOS signal
transduction pathway. J Cardiovasc Pharmacol. 50:2742007.
View Article : Google Scholar : PubMed/NCBI
|
37
|
Brunet A, Datta SR and Greenberg ME:
Transcription-dependent and -independent control of neuronal
survival by the PI3K-Akt signaling pathway. Curr Opin Neurobiol.
11:297–305. 2001. View Article : Google Scholar : PubMed/NCBI
|
38
|
Fang J, Ding M, Yang L, Liu L and Jiang B:
PI3K/PTEN/AKT signalling regulates prostate tumor angiogenesis.
Cell Signall. 19:2487–2497. 2007. View Article : Google Scholar
|
39
|
Karar J and Maity A: PI3K/AKT/mTOR Pathway
in Angiogenesis. Front Mol Neurosci. 4:512011. View Article : Google Scholar : PubMed/NCBI
|
40
|
Shayesteh L, Lu Y, Kuo WL, Baldocchi R,
Godfrey T, Collins C, Pinkel D, Powell B, Mills GB and Gray JW:
PIK3CA is implicated as an oncogene in ovarian cancer. Nat Genet.
21:99–102. 1999. View
Article : Google Scholar : PubMed/NCBI
|
41
|
Bellacosa A, De Feo D, Godwin AK, Bell DW,
Cheng JQ, Altomare DA, Wan M, Dubeau L, Scambia G, Masciullo V, et
al: Molecular alterations of the AKT2 oncogene in ovarian and
breast carcinomas. Int J Cancer. 64:280–285. 1995. View Article : Google Scholar : PubMed/NCBI
|
42
|
Roy HK, Olusola BF, Clemens DL, Karolski
WJ, Ratashak A, Lynch HT and Smyrk TC: AKT proto-oncogene
overexpression is an early event during sporadic colon
carcinogenesis. Carcinogenesis. 23:2012002. View Article : Google Scholar : PubMed/NCBI
|
43
|
Lee KB, Byun HJ, Park SH, Park CY, Lee SH
and Rho SB: CYR61 controls p53 and NF-κB expression through
PI3K/Akt/mTOR pathways in carboplatin-induced ovarian cancer cells.
Cancer Lett. 315:86–95. 2012. View Article : Google Scholar : PubMed/NCBI
|
44
|
Wang T, Yuan J, Feng N, Li Y, Lin Z, Jiang
Z and Gui Y: Hsa-miR-1 downregulates long non-coding RNA urothelial
cancer associated 1 in bladder cancer. Tumour Biol. 35:10075–10084.
2014. View Article : Google Scholar : PubMed/NCBI
|
45
|
Zheng Q, Wu F, Dai WY, Zheng DC, Zheng C,
Ye H, Zhou B, Chen JJ and Chen P: Aberrant expression of UCA1 in
gastric cancer and its clinical significance. Clin Transl Onco.
17:640–646. 2015. View Article : Google Scholar
|
46
|
Han Y, Yang YN, Yuan HH, Zhang TT, Sui H,
Wei XL, Liu L, Huang P, Zhang WJ and Bai YX: UCA1, a long
non-coding RNA up-regulated in colorectal cancer influences cell
proliferation, apoptosis and cell cycle distribution. Pathology.
46:396–401. 2014. View Article : Google Scholar : PubMed/NCBI
|
47
|
Wang F, Ying HQ, He BS, Pan YQ, Deng QW,
Sun HL, Chen J, Liu X and Wang SK: Upregulated lncRNA-UCA1
contributes to progression of hepatocellular carcinoma through
inhibition of miR-216b and activation of FGFR1/ERK signaling
pathway. Oncotarget. 6:78992015.PubMed/NCBI
|
48
|
Yang C, Li X, Wang Y, Zhao L and Chen W:
Long non-coding RNA UCA1 regulated cell cycle distribution via CREB
through PI3-K dependent pathway in bladder carcinoma cells. Gene.
496:82012. View Article : Google Scholar : PubMed/NCBI
|
49
|
Wang W: mRNA methylation by NSUN2 in cell
proliferation. Wiley Interdiscip Rev RNA. 7:838–842. 2016.
View Article : Google Scholar : PubMed/NCBI
|
50
|
Venkatraman A, He XC, Thorvaldsen JL,
Sugimura R, Perry JM, Tao F, Zhao M, Christenson MK, Sanchez R, Yu
JY, et al: Maternal imprinting at the H19-Igf2 locus maintains
adult haematopoietic stem cell quiescence. Nature. 500:345–349.
2013. View Article : Google Scholar : PubMed/NCBI
|
51
|
Gabory A, Ripoche MA, Le Digarcher A,
Watrin F, Ziyyat A, Forné T, Jammes H, Ainscough JF, Surani MA,
Journot L and Dandolo L: H19 acts as a trans regulator of the
imprinted gene networkcontrolling growth in mice. Development.
136:3413–3421. 2009. View Article : Google Scholar : PubMed/NCBI
|
52
|
Debaun MR, Niemitz EL and Feinberg AP:
Association of in vitro fertilization with Beckwith-Wiedemann
syndrome and epigenetic alterations of LIT1 and H19. Am J Hum
Genet. 72:156–160. 2003. View
Article : Google Scholar : PubMed/NCBI
|
53
|
Steenman MJ, Rainier S, Dobry CJ, Grundy
P, Horon IL and Feinberg AP: Loss of imprinting of IGF2 is linked
to reduced expression and abnormal methylation of H19 in Wilms'
tumour. Nat Genet. 7:433–439. 1994. View Article : Google Scholar : PubMed/NCBI
|
54
|
Hibi K, Nakamura H, Hirai A, Fujikake Y,
Kasai Y, Akiyama S, Ito K and Takagi H: Loss of H19 imprinting in
esophageal cancer. Cancer Res. 56:4801996.PubMed/NCBI
|
55
|
Barsytelovejoy D, Lau SK, Boutros PC,
Khosravi F, Jurisica I, Andrulis IL, Tsao MS and Penn LZ: The c-Myc
oncogene directly induces the H19 noncoding RNA by allele-specific
binding to potentiate tumorigenesis. Cancer Res. 66:53302006.
View Article : Google Scholar : PubMed/NCBI
|
56
|
Yang Z, Lu Y, Xu Q, Tang B, Park CK and
Chen X: HULC and H19 played different roles in overall and
disease-free survival from hepatocellular carcinoma after curative
hepatectomy: A preliminary analysis from gene expression omnibus.
Dis Markers. 2015:1910292015. View Article : Google Scholar : PubMed/NCBI
|
57
|
Xu J, Xia Y, Zhang H, Guo H, Feng K and
Zhang C: Overexpression of long non-coding RNA H19 promotes
invasion and autophagy via the PI3K/AKT/mTOR pathways in
trophoblast cells. Biomed Pharmacother. 101:691–697. 2018.
View Article : Google Scholar : PubMed/NCBI
|