Management of perivascular epithelioid cell tumor of the liver: A case report and review of the literature

  • Authors:
    • Daren Liu
    • Dike Shi
    • Yuanliang Xu
    • Liping Cao
  • View Affiliations

  • Published online on: November 19, 2013     https://doi.org/10.3892/ol.2013.1689
  • Pages: 148-152
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Perivascular epithelioid cell tumor (PEComa) is a rare tumor that originates from mesenchymal tissues. Cases of PEComa in the liver are extremely rare. The present study aimed to analyze the clinical features of PEComa in the liver and discuss its management. Here we report a 25-year-old female with multiple lesions of low density with poorly defined borders in the liver, as shown by a computed tomography (CT) scan. A partial hepatectomy was proceeded and PEComa was diagnosed by immunohistochemistry. No evidence of recurrence was observed during the one year follow-up. A total of 20 patients with hepatic PEComa, including one case from the present study and 19 cases that were reported in literature between June 2001 and December 2012, were reviewed and analyzed. The mean patient age was 43.4 years (range, 25‑67 years) and the cases consisted of 18 female and two male patients. The tumor size ranged between 2.0x1.6 and 15.0x12.0 cm. Of the 20 patients, nine were asymptomatic and 11 had mild to significant complaints. Immunohistochemistry plays a key role in the diagnosis of PEComa. All the cases in this study were strongly positive for human melanoma black‑45. A surgical resection is the gold standard for curative intent. All the patients underwent a surgical resection and none were administered perioperative chemotherapy or radiotherapy. In total, 13 of the 14 patients with follow‑up information survived during the 8‑36‑month follow‑up period and one patient succumbed due to recurrence two years after the surgery.
View Figures
View References

Related Articles

Journal Cover

2014-January
Volume 7 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Liu D, Shi D, Xu Y and Cao L: Management of perivascular epithelioid cell tumor of the liver: A case report and review of the literature. Oncol Lett 7: 148-152, 2014.
APA
Liu, D., Shi, D., Xu, Y., & Cao, L. (2014). Management of perivascular epithelioid cell tumor of the liver: A case report and review of the literature. Oncology Letters, 7, 148-152. https://doi.org/10.3892/ol.2013.1689
MLA
Liu, D., Shi, D., Xu, Y., Cao, L."Management of perivascular epithelioid cell tumor of the liver: A case report and review of the literature". Oncology Letters 7.1 (2014): 148-152.
Chicago
Liu, D., Shi, D., Xu, Y., Cao, L."Management of perivascular epithelioid cell tumor of the liver: A case report and review of the literature". Oncology Letters 7, no. 1 (2014): 148-152. https://doi.org/10.3892/ol.2013.1689