1
|
Sekido Y, Fong KM and Minna JD: Progress
in understanding the molecular pathogenesis of human lung cancer.
Biochim Biophys Acta. 1378:F21–F59. 1998.PubMed/NCBI
|
2
|
Smith W and Khuri FR: The care of the lung
cancer patient in the 21st century: a new age. Semin Oncol. 31(2
Suppl 4): S11–S15. 2004. View Article : Google Scholar : PubMed/NCBI
|
3
|
Klaus A and Birchmeier W: Wnt signalling
and its impact on development and cancer. Nat Rev Cancer.
8:387–398. 2008. View
Article : Google Scholar : PubMed/NCBI
|
4
|
Ohgaki H, Kros JM, Okamoto Y, Gaspert A,
Huang H and Kurrer MO: APC mutations are infrequent but present in
human lung cancer. Cancer Lett. 207:197–203. 2004. View Article : Google Scholar
|
5
|
Sunaga N, Kohno T, Kolligs FT, Fearon ER,
Saito R and Yokota J: Constitutive activation of the Wnt signaling
pathway by CTNNB1 (beta-catenin) mutations in a subset of human
lung adenocarcinoma. Genes Chromosomes Cancer. 30:316–321. 2001.
View Article : Google Scholar : PubMed/NCBI
|
6
|
He B, You L, Uematsu K, et al: A
monoclonal antibody against Wnt-1 induces apoptosis in human cancer
cells. Neoplasia. 6:7–14. 2004. View Article : Google Scholar : PubMed/NCBI
|
7
|
You L, He B, Xu Z, et al: Inhibition of
Wnt-2-mediated signaling induces programmed cell death in
non-small-cell lung cancer cells. Oncogene. 23:6170–6174. 2004.
View Article : Google Scholar : PubMed/NCBI
|
8
|
Winn RA, Marek L, Han SY, et al:
Restoration of Wnt-7a expression reverses non-small cell lung
cancer cellular transformation through frizzled-9-mediated growth
inhibition and promotion of cell differentiation. J Biol Chem.
280:19625–19634. 2005. View Article : Google Scholar
|
9
|
Uematsu K, He B, You L, Xu Z, McCormick F
and Jablons DM: Activation of the Wnt pathway in non small cell
lung cancer: evidence of dishevelled overexpression. Oncogene.
22:7218–7221. 2003. View Article : Google Scholar : PubMed/NCBI
|
10
|
Fukui T, Kondo M, Ito G, et al:
Transcriptional silencing of secreted frizzled related protein 1
(SFRP 1) by promoter hypermethylation in non-small-cell lung
cancer. Oncogene. 24:6323–6327. 2005. View Article : Google Scholar : PubMed/NCBI
|
11
|
Wissmann C, Wild PJ, Kaiser S, et al:
WIF1, a component of the Wnt pathway, is down-regulated in
prostate, breast, lung, and bladder cancer. J Pathol. 201:204–212.
2003. View Article : Google Scholar : PubMed/NCBI
|
12
|
Mazieres J, He B, You L, et al: Wnt
inhibitory factor-1 is silenced by promoter hypermethylation in
human lung cancer. Cancer Res. 64:4717–4720. 2004. View Article : Google Scholar : PubMed/NCBI
|
13
|
Ueda M, Gemmill RM, West J, et al:
Mutations of the beta- and gamma-catenin genes are uncommon in
human lung, breast, kidney, cervical and ovarian carcinomas. Br J
Cancer. 85:64–68. 2001. View Article : Google Scholar : PubMed/NCBI
|
14
|
You L, He B, Xu Z, et al: An anti-Wnt-2
monoclonal antibody induces apoptosis in malignant melanoma cells
and inhibits tumor growth. Cancer Res. 64:5385–5389. 2004.
View Article : Google Scholar : PubMed/NCBI
|
15
|
Jackson AL, Bartz SR, Schelter J, et al:
Expression profiling reveals off-target gene regulation by RNAi.
Nat Biotechnol. 21:635–637. 2003. View
Article : Google Scholar : PubMed/NCBI
|
16
|
Pongracz JE and Stockley RA: Wnt
signalling in lung development and diseases. Respir Res. 7:152006.
View Article : Google Scholar : PubMed/NCBI
|
17
|
Fukukawa C, Nagayama S, Tsunoda T,
Toguchida J, Nakamura Y and Katagiri T: Activation of the
non-canonical Dvl-Rac1-JNK pathway by Frizzled homologue 10 in
human synovial sarcoma. Oncogene. 28:1110–1120. 2009. View Article : Google Scholar : PubMed/NCBI
|
18
|
Jin X, Jeon HY, Joo KM, et al: Frizzled 4
regulates stemness and invasiveness of migrating glioma cells
established by serial intracranial transplantation. Cancer Res.
71:3066–3075. 2011. View Article : Google Scholar
|
19
|
Rhee CS, Sen M, Lu D, et al: Wnt and
frizzled receptors as potential targets for immunotherapy in head
and neck squamous cell carcinomas. Oncogene. 21:6598–6605. 2002.
View Article : Google Scholar : PubMed/NCBI
|
20
|
Tanaka S, Akiyoshi T, Mori M, Wands JR and
Sugimachi K: A novel frizzled gene identified in human esophageal
carcinoma mediates APC/beta-catenin signals. Proc Natl Acad Sci
USA. 95:10164–10169. 1998. View Article : Google Scholar : PubMed/NCBI
|
21
|
To KF, Chan MW, Leung WK, et al:
Alterations of frizzled (FzE3) and secreted frizzled related
protein (hsFRP) expression in gastric cancer. Life Sci. 70:483–489.
2001. View Article : Google Scholar : PubMed/NCBI
|
22
|
Ueno K, Hazama S, Mitomori S, et al:
Down-regulation of frizzled-7 expression decreases survival,
invasion and metastatic capabilities of colon cancer cells. Br J
Cancer. 101:1374–1381. 2009. View Article : Google Scholar : PubMed/NCBI
|
23
|
Zeng G, Germinaro M, Micsenyi A, et al:
Aberrant Wnt/beta-catenin signaling in pancreatic adenocarcinoma.
Neoplasia. 8:279–289. 2006. View Article : Google Scholar : PubMed/NCBI
|
24
|
DeAlmeida VI, Miao L, Ernst JA, Koeppen H,
Polakis P and Rubinfeld B: The soluble wnt receptor
Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo.
Cancer Res. 67:5371–5379. 2007. View Article : Google Scholar : PubMed/NCBI
|
25
|
de la Roche M, Rutherford TJ, Gupta D, et
al: An intrinsically labile alpha-helix abutting the BCL9-binding
site of beta-catenin is required for its inhibition by carnosic
acid. Nat Commun. 3:6802012.PubMed/NCBI
|
26
|
Takada K, Zhu D, Bird GH, et al: Targeted
disruption of the BCL9/beta-catenin complex inhibits oncogenic Wnt
signaling. Sci Transl Med. 4:148ra1172012. View Article : Google Scholar : PubMed/NCBI
|