Open Access

Role of four and a half LIM domain protein 1 in tumors (Review)

  • Authors:
    • Yun Tao
    • Yaxun Wu
    • Rong Shen
    • Song He
    • Xiaobing Miao
  • View Affiliations

  • Published online on: October 29, 2024     https://doi.org/10.3892/ol.2024.14783
  • Article Number: 37
  • Copyright: © Tao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

As a cytoskeletal protein, the four and a half LIM domain protein 1 (FHL1) is widely expressed in various cells, particularly skeletal and cardiac muscle cells. FHL1 is involved in the development of the skeletal muscle and myocardium, regulations of gene transcription and thyroid function, and other physiological processes. Its expression is closely related to numerous diseases, such as skeletal muscle disease and viral infections. With the advances in research, the role of FHL1 in the development of tumors is also being revealed. The mechanism of FHL1 in the regulation of tumor growth is complex and is becoming a research focus. It is also expected to become a potential target for tumor therapy. Therefore, the present article reviewed the progress in research on the role of FHL1 in cancer.
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January-2025
Volume 29 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Tao Y, Wu Y, Shen R, He S and Miao X: Role of four and a half LIM domain protein 1 in tumors (Review). Oncol Lett 29: 37, 2025.
APA
Tao, Y., Wu, Y., Shen, R., He, S., & Miao, X. (2025). Role of four and a half LIM domain protein 1 in tumors (Review). Oncology Letters, 29, 37. https://doi.org/10.3892/ol.2024.14783
MLA
Tao, Y., Wu, Y., Shen, R., He, S., Miao, X."Role of four and a half LIM domain protein 1 in tumors (Review)". Oncology Letters 29.1 (2025): 37.
Chicago
Tao, Y., Wu, Y., Shen, R., He, S., Miao, X."Role of four and a half LIM domain protein 1 in tumors (Review)". Oncology Letters 29, no. 1 (2025): 37. https://doi.org/10.3892/ol.2024.14783